GADD45G(growth arrest and DNA-damage-inducible, gamma) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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9q22.1-q22.2
基因染色体位置图

This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The protein encoded by this gene responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The GADD45G is highly expressed in placenta. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  此基因是一组基因,其转录水平增加以下压力的生长停滞条件和与DNA损伤剂治疗中的一员。由该基因编码的蛋白质通过介导通过MTK1 / MEKK4激酶的p38 / JNK途径的活化来响应环境压力。该GADD45G在胎盘中高度表达。 [由RefSeq的,2008年7月提供]

GADD45G基因的碱基序列:[NCBI]
GADD45G基因的碱基突变:           显示全部snp
rs8252       rs1329732       rs2031968       rs2031969       rs2183297       rs3138482       rs3138483       rs3138484       rs3138485       rs3138486       rs3138487       rs3138488       rs3138489       rs3138490       rs3138491       rs3138492       rs3138493       rs3138494       rs3138495       rs3138496       rs3138497       rs3138498       rs3138499       rs3138500       rs3138501       rs3138502       rs3138503       rs3138504       rs3138505       rs3138506       rs3138507       rs3138508       rs3138509       rs3138510       rs5031028       rs5031029       rs11265837      
rs34954994       rs56370514       rs62559576       rs62559577       rs71512212       rs73492189       rs75573381       rs77788192       rs80063572       rs112350085       rs112620591       rs112757285       rs113485528       rs113577228       rs116045568       rs116507170       rs138340972       rs138848476       rs139199769       rs139830638       rs141169302       rs141546792       rs143347350       rs144775138       rs144997883       rs145026737       rs145962111       rs148149951       rs148348813       rs149629105       rs149946162       rs150711527       rs180716901       rs182701147       rs187821449       rs188420872       rs189463663       rs189468471       rs192194938       rs192792125       rs199566315       rs200114148       rs200515719       rs201461933       rs201824646       rs202172169       rs367604612       rs368136463       rs371625737       rs371764432       rs372539162       rs374588217       rs375022979       rs375895752       rs376168420       rs376998051       rs377237154       rs527819772       rs528098244       rs530248505       rs531182995       rs531333805       rs532244037       rs533175423       rs533501852       rs535732211       rs537995653       rs539695299       rs539782458       rs540413349       rs540480486       rs541501949       rs541605673       rs541842336       rs541866124       rs542555969       rs543245547       rs545793398       rs545878741       rs546961221       rs548404467       rs548633721       rs548701191       rs549270126       rs549977578       rs550963372       rs550988377       rs552184064       rs552785403       rs553901999       rs554123628       rs554746650       rs555194842       rs556189999       rs556750242       rs558325987       rs560143555       rs560394261       rs561360202       rs561482920       rs561884370       rs562153532       rs562861030       rs563060536       rs563549010       rs564551830       rs565339805       rs567923915       rs568211849       rs569606778       rs570704051       rs570992555       rs572135542       rs574666176       rs575071107       rs575108849       rs576076089       rs576653923       rs576878962       rs577033897       rs745513682       rs745673173       rs746135313       rs746237447       rs746669814       rs746693195       rs747100436       rs747635391       rs747971986       rs748093899       rs748525971       rs749129840       rs749453672       rs749808520       rs749859633       rs750023036       rs750403030       rs750661212       rs750824488       rs751083768       rs751325466       rs751783234       rs752571534       rs752722256       rs753177392       rs753797196       rs754245950       rs754612950       rs755053870       rs755419905       rs756178368       rs756436120       rs757126101       rs757203626       rs758170913       rs758352700       rs758400370       rs758531493       rs758761212       rs759075859       rs759232998       rs759732445       rs759734692       rs760266006       rs760626272       rs761016687       rs761892023       rs762285868       rs762447357       rs763211787       rs763440749       rs764687256       rs765165632       rs765749796       rs766068213       rs766131826       rs766729414       rs766888067       rs767050931       rs767578713       rs767626463       rs767645032       rs768095527       rs768678190       rs769464900       rs769776007       rs770383550       rs770448151       rs770736711       rs771247864       rs772824250       rs773959839       rs774186008       rs774543865       rs774642149       rs774715512       rs775043958       rs776071768       rs776163941       rs776521244       rs777177780       rs777483869       rs778609793       rs778804463       rs778856888       rs779652554       rs779774760       rs780217513       rs780697159       rs781177555       rs781458866       rs781467856       rs3138511       rs144758335       rs541424179       rs558225752      

GADD45G基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CCAAAGTCTTGAACGTGGAC
60
AGCAGAAAGCCTGGATCAG
60
CAAAGTCTTGAACGTGGACC
60
AGCAGAAAGCCTGGATCAG
60
TTGAACGTGCTTTCTGCTG
59
GAAATGAGGATGCAGTGCAG
60
CCAAAGTCTTGAACGTGGAC
60
AGCAGAAAGCCTGGATCAG
60
CAAAGTCTTGAACGTGGACC
60
AGCAGAAAGCCTGGATCAG
60
AAAGTCTTGAACGTGGACC
58
TATGTCGATGTCGTTCTCG
57
TTGAACGTGCTTTCTGCTG
59
AAATGAGGATGCAGTGCAG
59
CTTGAACGTGCTTTCTGCT
59
AAATGAGGATGCAGTGCAG
59
AAAGTCTTGAACGTGGACC
58
TATGTCGATGTCGTTCTCG
57
      尚未收录相关数据

GADD45G基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

GADD45G基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0000185
O95257(UniProtKB)
IDA
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005515
O95257(UniProtKB)
IPI
GO:0005634
O95257(UniProtKB)
IDA
GO:0005737
O95257(UniProtKB)
IDA
GO:0006915
O95257(UniProtKB)
IEA
GO:0006950
O95257(UniProtKB)
IEA
GO:0007275
O95257(UniProtKB)
IEA
GO:0030154
O95257(UniProtKB)
IEA
GO:0043065
O95257(UniProtKB)
IDA
GO:0046330
O95257(UniProtKB)
IDA
GO:0051726
O95257(UniProtKB)
IEA
GO:1900745
O95257(UniProtKB)
IDA
GO:0005634
Q5VZ88(UniProtKB)
IEA
GO:0006950
Q5VZ88(UniProtKB)
IEA
GO:0051726
Q5VZ88(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控GADD45G基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Carcinogenesis 0.003800186 14 0 BeFree
Pituitary Neoplasms 0.003538676 3 0 BeFree_LHGDN
Liver carcinoma 0.003267234 2 0 BeFree_LHGDN
Alcoholic Intoxication, Chronic 0.002367032 1 1 GAD
Epithelial ovarian cancer 0.002367032 1 0 GAD
Malignant neoplasm of lung 0.001900093 7 0 BeFree
Carcinoma of lung 0.001900093 7 0 BeFree
Pituitary Adenoma 0.000814326 3 0 BeFree
Carcinogenicity 0.000814326 3 0 BeFree
Adenoma 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Squamous cell carcinoma of esophagus 0.000542884 2 0 BeFree
Malignant neoplasm of pancreas 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Congenital chromosomal disease 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Esophageal Neoplasms 0.000271442 1 0 BeFree
Fanconi Anemia 0.000271442 1 0 BeFree
Kidney Diseases 0.000271442 1 0 BeFree
Lung diseases 0.000271442 1 0 BeFree
Lung Neoplasms 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Nephritis 0.000271442 1 0 BeFree
Pituitary Diseases 0.000271442 1 0 BeFree
Giant Cell Arteritis 0.000271442 1 0 BeFree
Teratoma 0.000271442 1 0 BeFree
Ureteral obstruction 0.000271442 1 0 BeFree
Esophageal carcinoma 0.000271442 1 0 BeFree
Chronic glomerulonephritis 0.000271442 1 0 BeFree
Macrocephaly 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Multiple tumors 0.000271442 1 0 BeFree
Non-Functioning Pituitary Gland Neoplasm 0.000271442 1 0 BeFree
Malignant neoplasm of esophagus 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Gastric Cardia Adenocarcinoma 0.000271442 1 0 BeFree
Tumor Angiogenesis 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Nasopharyngeal carcinoma 0.000271442 1 0 BeFree
FANCONI ANEMIA, COMPLEMENTATION GROUP A (disorder) 0.000271442 1 0 BeFree
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