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The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the soluble A and B antigen synthesis pathway. This gene is one of two encoding the galactoside 2-L-fucosyltransferase enzyme. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  由该基因编码的蛋白质是参与创建H抗原,这是需要的可溶性A中的最后一个步骤和B抗原合成途径的前体的一个高尔基叠层膜蛋白。该基因是编码半乳糖苷-2-L-岩藻糖转移酶的两个一。已发现了该基因编码的蛋白质相同的两个转录变异体。 [由RefSeq的,2008年7月提供]
FUT2基因(以及对应的蛋白质)的细胞分布位置:
FUT2基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Crohn Disease | 0.247177041 | 11 | 2 | BeFree_CTD_human_GAD_GWASCAT |
Psoriasis | 0.12 | 1 | 1 | GWASCAT |
Caliciviridae Infections | 0.12 | 1 | 0 | CTD_human |
VITAMIN B12 PLASMA LEVEL QUANTITATIVE TRAIT LOCUS 1 | 0.12 | 0 | 0 | CTD_human |
Helicobacter pylori infection | 0.014745076 | 8 | 0 | BeFree_GAD |
Enteritis due to Norovirus | 0.007101096 | 3 | 0 | GAD |
Malignant neoplasm of urinary bladder | 0.004734064 | 2 | 0 | GAD |
HIV Infections | 0.003181358 | 3 | 0 | BeFree_GAD |
Infection | 0.00272435 | 1 | 0 | LHGDN |
Malignant neoplasm of breast | 0.002638474 | 2 | 0 | BeFree_GAD |
Asthma | 0.002367032 | 1 | 0 | GAD |
Cystic Fibrosis | 0.002367032 | 1 | 0 | GAD |
Chronic Obstructive Airway Disease | 0.002367032 | 1 | 0 | GAD |
Parkinson Disease | 0.002367032 | 1 | 0 | GAD |
Prostatic Neoplasms | 0.002367032 | 1 | 0 | GAD |
Pseudomonas Infections | 0.002367032 | 1 | 0 | GAD |
Rheumatoid Arthritis | 0.001628651 | 6 | 0 | BeFree |
Ovarian Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Primary sclerosing cholangitis | 0.001085767 | 4 | 0 | BeFree |
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site | 0.000814326 | 3 | 0 | BeFree |
Staphylococcal toxic shock syndrome | 0.000814326 | 3 | 0 | BeFree |
Cholangitis, Sclerosing | 0.000542884 | 2 | 1 | BeFree |
Inflammatory Bowel Diseases | 0.000542884 | 2 | 1 | BeFree |
Malignant neoplasm of stomach | 0.000542884 | 2 | 0 | BeFree |
Staphylococcal Food Poisoning | 0.000542884 | 2 | 0 | BeFree |
Pancreatic carcinoma | 0.000542884 | 2 | 0 | BeFree |
MRSA - Methicillin resistant Staphylococcus aureus infection | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of pancreas | 0.000542884 | 2 | 0 | BeFree |
Toxic Shock Syndrome | 0.000542884 | 2 | 0 | BeFree |
Epithelial ovarian cancer | 0.000542884 | 2 | 0 | BeFree |
Stomach Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of ovary | 0.000542884 | 2 | 0 | BeFree |
Acute pancreatitis | 0.000271442 | 1 | 0 | BeFree |
Anemia | 0.000271442 | 1 | 0 | BeFree |
Autoimmune Diseases | 0.000271442 | 1 | 0 | BeFree |
Behcet Syndrome | 0.000271442 | 1 | 0 | BeFree |
Candidiasis | 0.000271442 | 1 | 0 | BeFree |
Malignant tumor of colon | 0.000271442 | 1 | 0 | BeFree |
Cholangitis | 0.000271442 | 1 | 1 | BeFree |
Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Mental Depression | 0.000271442 | 1 | 0 | BeFree |
Depressive disorder | 0.000271442 | 1 | 0 | BeFree |
Diabetes Mellitus, Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
Gastritis | 0.000271442 | 1 | 0 | BeFree |
Gastroenteritis | 0.000271442 | 1 | 0 | BeFree |
Graves Disease | 0.000271442 | 1 | 0 | BeFree |
Hemochromatosis | 0.000271442 | 1 | 5 | BeFree |
Ileitis | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 2 | BeFree |
Pancreatic Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Sudden infant death syndrome | 0.000271442 | 1 | 0 | BeFree |
Virus Diseases | 0.000271442 | 1 | 0 | BeFree |
Vitamin B 12 Deficiency | 0.000271442 | 1 | 0 | BeFree |
Pancreatitis, Chronic | 0.000271442 | 1 | 0 | BeFree |
Cholangiocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Colon Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
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