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This gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full-length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full-length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell-cell junctions in an E-cadherin-dependent manner, and is selectively localized at the basolateral membrane in polarized epithelial cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2009]
[中文简述(自动翻译):]  这个基因编码的周膜蛋白,并位于包含一个片段复制染色体10q的区域。该基因的这个副本是全长和在端粒重复区域。该基因的其他两个以上centromerically近副本是局部的,可能代表假。这个全长基因出现在建立和小区极化的维护工作。该蛋白被募集至细胞 - 细胞连接在E-钙粘蛋白依赖性,并且在极化上皮细胞基底外侧膜选择性地定位。选择性剪接结果在多个抄本变形。 [由RefSeq的,2009年12月提供]
FRMPD2基因(以及对应的蛋白质)的细胞分布位置:
FRMPD2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
| synovial sarcoma | 0.000271442 | 1 | 0 | BeFree |
| Sicca Syndrome | 0.000271442 | 1 | 0 | BeFree |
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