FOSL1(FOS-like antigen 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

11q13
基因染色体位置图

基因简述

基因简述

The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

[中文简述(自动翻译):]  果寡糖基因家族由4名成员：FOS，FOSB，FOSL1和FOSL2。这些基因编码亮氨酸拉链蛋白可与君家的蛋白质二聚化，由此形成的转录因子复合的AP-1。因此，FOS蛋白质有牵连的细胞增殖，分化和转型的监管。已发现该基因编码不同亚型的几个抄本变形。 [由RefSeq的，2014年7月提供]

OMIM数据库中对FOSL1基因的介绍     Wikipedia数据库中对FOSL1基因的介绍

基因序列

基因序列

FOSL1基因的碱基序列：[NCBI]

基因突变

基因突变

FOSL1基因的碱基突变：           显示全部snp
rs35831421       rs57225106       rs76584642       rs191208167       rs374781493       rs530520870       rs535329555       rs537552203       rs541465585       rs550219051       rs552718046       rs555047894       rs557143072       rs568417604       rs570244449       rs507062       rs536383       rs538268       rs585557       rs588114       rs608616       rs614520       rs618544       rs622614       rs634534       rs637571       rs689274       rs1058068       rs1143711       rs1151520       rs1151523       rs4013977       rs7128298       rs7950010       rs7950277       rs7951094       rs9326357      
rs9919533       rs10160792       rs10791830       rs11227334       rs11227335       rs11227337       rs11227338       rs11227339       rs11227341       rs11550914       rs11825070       rs12576224       rs17174108       rs34668017       rs35205552       rs58568715       rs67489955       rs71036251       rs71036252       rs72924800       rs73494420       rs73494422       rs73494424       rs73494440       rs74369199       rs75003447       rs75863223       rs76308156       rs76804386       rs77537829       rs77544146       rs77648808       rs77920938       rs78163657       rs79728957       rs79944279       rs80254363       rs111301320       rs111750242       rs112017120       rs112201369       rs112365281       rs112755115       rs112865376       rs112993601       rs113743498       rs113768073       rs113876695       rs114219957       rs114698900       rs114787843       rs114984248       rs115363285       rs116227393       rs116320355       rs138397091       rs139093911       rs139306103       rs139675472       rs139714029       rs140186830       rs140249485       rs140832940       rs141568548       rs141976219       rs142119979       rs142205529       rs142924409       rs143002896       rs143903781       rs144674872       rs144760068       rs144980043       rs145058249       rs145194278       rs145226916       rs145375154       rs145383050       rs145451938       rs146406795       rs146443004       rs146452451       rs147820516       rs148163955       rs148361943       rs148517764       rs149112693       rs149114448       rs149444153       rs150491205       rs150615201       rs151147129       rs151155428       rs180875695       rs181413227       rs181499092       rs181614817       rs181979051       rs182954794       rs183477428       rs184050084       rs184286583       rs184378730       rs184519609       rs185346703       rs186058454       rs186328149       rs186615869       rs186781489       rs187981011       rs187995985       rs188814278       rs189350371       rs189750759       rs190453047       rs190628862       rs190968425       rs191333882       rs192220727       rs192559198       rs192800608       rs199739330       rs199745694       rs199932238       rs200164844       rs200326243       rs201410689       rs201418296       rs367622442       rs367718925       rs367968126       rs368289347       rs368437358       rs368497099       rs368840880       rs369289692       rs370021821       rs370157567       rs370607362       rs370714745       rs371316315       rs371886513       rs372288292       rs373357753       rs373389443       rs373488028       rs373742155       rs374499277       rs374811980       rs374936975       rs375012989       rs375933462       rs376236890       rs376301362       rs377361358       rs377377471       rs527532473       rs528165998       rs528663296       rs528788060       rs528798272       rs529217789       rs529353344       rs530020801       rs530256533       rs530389290       rs530619349       rs530962033       rs531114435       rs531698076       rs531986458       rs532423712       rs532711513       rs532973186       rs533033363       rs533248744       rs533259252       rs533444546       rs533801989       rs533840514       rs534964747       rs535047087       rs535139920       rs535297242       rs535316650       rs535377602       rs536280577       rs536964598       rs537162271       rs537470040       rs537551443       rs537748936       rs537882530       rs538142752       rs538552042       rs538691075       rs538737006       rs539280584       rs539314501       rs539368572       rs539918153       rs539968194       rs540212750       rs540285077       rs541266164       rs541351441       rs541400469       rs541463918       rs541673511       rs542034435       rs542471693       rs542647953       rs542737554       rs543290366       rs543717149       rs543925907       rs543996894       rs544255506       rs544537567       rs544598629       rs545147421       rs545712910       rs546653913       rs546654738       rs547035485       rs547586118       rs547591812       rs548389258       rs548589247       rs549025964       rs549767213       rs550153243       rs550333238       rs550681592       rs550744610       rs551023982       rs551212950       rs551598160       rs552140776       rs552539918       rs552626300       rs552740241       rs552874012       rs553616226       rs553792931       rs554018580       rs554738036       rs554814992       rs555138231       rs555734771       rs555935692       rs556002374       rs556265430       rs557111251       rs557306815       rs557461987       rs557472138       rs557997837       rs558060967       rs558878871       rs558938218       rs558949257       rs558982223       rs558996602       rs559903574       rs559987733       rs560123565       rs560125985       rs561061219       rs561480190       rs561959251       rs562401706       rs562436264       rs562498676       rs563312328       rs563747379       rs564056645       rs564101721       rs564153809       rs564828470       rs565473723       rs566040137       rs566101535       rs566261294       rs566353279       rs567477761       rs568398057       rs568483244       rs569036060       rs570150007       rs570307156       rs570756562       rs570896738       rs571223546       rs571532302       rs571542564       rs572617473       rs572658659       rs572844950       rs572848732       rs573826810       rs573975610       rs574575051       rs575142940       rs575175881       rs575661735       rs575756910       rs575896629       rs576033010       rs576321480       rs576931475       rs577525233       rs577586672       rs577798180       rs577861959       rs577901934       rs745369622       rs745518234       rs745825650       rs746291005       rs747120128       rs747333480       rs747527827       rs748182697       rs748274482       rs748610244       rs748853345       rs749251321       rs749528902       rs749672069       rs749967518       rs750124164       rs750176184       rs750196473       rs750484930       rs750962628       rs751184760       rs751483705       rs751711445       rs751940389       rs752121425       rs752420600       rs753130318       rs753232286       rs753502901       rs753702419       rs754196763       rs754319918       rs755145060       rs755168615       rs755750490       rs755943235       rs756162978       rs756181696       rs756869534       rs757016523       rs757126452       rs757135930       rs757312993       rs758400684       rs758410472       rs759043572       rs759198105       rs759636377       rs759839379       rs759845101       rs760036384       rs760600411       rs760977276       rs761174414       rs762124566       rs762190704       rs763350763       rs763900378       rs764005099       rs764049274       rs764454207       rs765242580       rs765459286       rs765594162       rs765698295       rs766168314       rs766770123       rs766841945       rs766867745       rs767082299       rs767141115       rs767326258       rs767546804       rs767788388       rs768098467       rs768177807       rs768594766       rs768932313       rs769128748       rs769224863       rs769751521       rs769884705       rs770119342       rs770591535       rs770821487       rs771352442       rs771440586       rs771678720       rs771929100       rs772440247       rs772706418       rs772755652       rs772768855       rs773068029       rs773439368       rs774090243       rs774398775       rs774942711       rs775345295       rs775417583       rs775917015       rs776577128       rs777020164       rs777051783       rs777911101       rs778285117       rs778388133       rs778680030       rs778837901       rs778946520       rs779055210       rs779084682       rs779143676       rs779633764       rs779730458       rs780080576       rs780287493       rs780461891       rs780851991       rs780967313       rs781327080       rs781685367       rs781777272      

基因表达

基因表达

FOSL1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGACCTACCCTCAGTACAG
57
TTTGTCAGTCTCCTGTTCAC
58
CTTGTGAACAGATCAGCCC
59
AAGTCGGTCAGTTCCTTCC
59
CGGAGACTGACAAACTGGA
59
GAAAGGAGTTAGGGAGGGT
58
AGGAGACTGACAAACTGGA
58
TCTGCAGCTCCTCAATCTC
59
TGACCTACCCTCAGTACAG
57
TTGTCAGTCTCCTGTTCAC
57
CCTTGTGAACAGATCAGCC
59
AAGTCGGTCAGTTCCTTCC
59
GACCTACCCTCAGTACAGC
59
AAGTCGGTCAGTTCCTTCC
59
CAGGAGACTGACAAACTGGA
59
TCTGCAGCTCCTCAATCTC
59
GACCTACCCTCAGTACAGC
59
GTTTGTCAGTCTCCTGTTCAC
59
GCCTTGTGAACAGATCAGC
59
GTCGGTCAGTTCCTTCCTC
60

转录因子

转录因子

转录因子
影响类型
PubMed链接
CLU
Unknown
10406964
EZH2
Unknown
23116973
GCLC
Unknown
16054171
ITGAV
Repression
23319049
ITGB3
Repression
23319049
IVL
Unknown
10816578     15790882    
MMP1
Unknown
18802113
PLAUR
Unknown
10471035     11234878    
SFTPD
Unknown
10915785

基因本体信息

FOSL1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

FOSL1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003677
E9PKL5(UniProtKB)
IEA
GO:0003700
E9PKL5(UniProtKB)
IEA
GO:0005634
E9PKL5(UniProtKB)
IDA
GO:0006357
E9PKL5(UniProtKB)
IEA
GO:0003677
E9PPX2(UniProtKB)
IEA
GO:0003700
E9PPX2(UniProtKB)
IEA
GO:0005634
E9PPX2(UniProtKB)
IDA
GO:0006357
E9PPX2(UniProtKB)
IEA
GO:0000978
P15407(UniProtKB)
IBA
GO:0000978
P15407(UniProtKB)
IDA
GO:0000982
P15407(UniProtKB)
IBA
GO:0001077
P15407(UniProtKB)
IEA
GO:0001701
P15407(UniProtKB)
IEA
GO:0003700
P15407(UniProtKB)
TAS
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005515
P15407(UniProtKB)
IPI
GO:0005634
P15407(UniProtKB)
IDA
GO:0005829
P15407(UniProtKB)
IEA
GO:0006357
P15407(UniProtKB)
TAS
GO:0006366
P15407(UniProtKB)
TAS
GO:0006935
P15407(UniProtKB)
TAS
GO:0006968
P15407(UniProtKB)
TAS
GO:0007296
P15407(UniProtKB)
IEA
GO:0007565
P15407(UniProtKB)
IEA
GO:0007612
P15407(UniProtKB)
IEA
GO:0008284
P15407(UniProtKB)
TAS
GO:0008285
P15407(UniProtKB)
IEA
GO:0009612
P15407(UniProtKB)
IEA
GO:0009615
P15407(UniProtKB)
TAS
GO:0009629
P15407(UniProtKB)
IEA
GO:0031668
P15407(UniProtKB)
IEA
GO:0032570
P15407(UniProtKB)
IEA
GO:0034097
P15407(UniProtKB)
IEA
GO:0042493
P15407(UniProtKB)
IEA
GO:0042542
P15407(UniProtKB)
IEA
GO:0042734
P15407(UniProtKB)
IEA
GO:0043005
P15407(UniProtKB)
IEA
GO:0043065
P15407(UniProtKB)
IEA
GO:0045787
P15407(UniProtKB)
IEA
GO:0045944
P15407(UniProtKB)
IEA
GO:0051091
P15407(UniProtKB)
IEA
GO:0051412
P15407(UniProtKB)
IEA
GO:0051591
P15407(UniProtKB)
IEA
GO:0060674
P15407(UniProtKB)
IEA
GO:0061614
P15407(UniProtKB)
IDA
GO:2000144
P15407(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控FOSL1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
IGA Glomerulonephritis 0.120271442 2 0 BeFree_CTD_human
Heart failure 0.08 1 0 RGD
Kidney Neoplasm 0.08 1 0 RGD
Reperfusion Injury 0.08 1 0 RGD
Seizures 0.08 1 0 RGD
Mammary Neoplasms 0.00408156 6 0 BeFree_LHGDN
Malignant neoplasm of breast 0.003800186 14 0 BeFree
Breast Carcinoma 0.003800186 14 0 BeFree
Glioma 0.003267234 2 0 BeFree_LHGDN
Lung Neoplasms 0.003267234 2 0 BeFree_LHGDN
Adenocarcinoma 0.002995792 1 0 BeFree_LHGDN
Astrocytoma 0.00272435 1 0 LHGDN
Carcinogenesis 0.001900093 7 0 BeFree
Neoplasm Metastasis 0.001628651 6 0 BeFree
Malignant tumor of cervix 0.000814326 3 0 BeFree
Tumor Progression 0.000814326 3 0 BeFree
Carcinoma breast stage IV 0.000814326 3 0 BeFree
Colorectal Cancer 0.000814326 3 0 BeFree
Malignant neoplasm of urinary bladder 0.000542884 2 0 BeFree
Breast Diseases 0.000542884 2 0 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 0 BeFree
Squamous cell carcinoma 0.000542884 2 0 BeFree
Colorectal Carcinoma 0.000542884 2 0 BeFree
Fragile X Syndrome 0.000542884 2 0 BeFree
Glioblastoma 0.000542884 2 0 BeFree
Psoriasis 0.000542884 2 0 BeFree
Chagas Disease 0.000542884 2 0 BeFree
Squamous cell carcinoma of esophagus 0.000542884 2 0 BeFree
Cervix carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Carcinoma of bladder 0.000542884 2 0 BeFree
Glioblastoma Multiforme 0.000542884 2 0 BeFree
Triple Negative Breast Neoplasms 0.000542884 2 0 BeFree
Adenoma 0.000271442 1 0 BeFree
Asthma 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Renal Cell Carcinoma 0.000271442 1 0 BeFree
Primary biliary cirrhosis 0.000271442 1 0 BeFree
Colonic Neoplasms 0.000271442 1 0 BeFree
Fibromatosis 0.000271442 1 0 BeFree
Goiter 0.000271442 1 0 BeFree
Chronic Obstructive Airway Disease 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Mental Retardation 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Pneumonia 0.000271442 1 0 BeFree
Adenomatous Polyposis Coli 0.000271442 1 0 BeFree
Pulmonary Emphysema 0.000271442 1 0 BeFree
Pulmonary Fibrosis 0.000271442 1 0 BeFree
Thyroid Diseases 0.000271442 1 0 BeFree
Thyroid Neoplasm 0.000271442 1 0 BeFree
Thyroid Nodule 0.000271442 1 0 BeFree
Fibromatosis, Aggressive 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Anaplastic carcinoma 0.000271442 1 0 BeFree
Undifferentiated carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Breast cancer stage II 0.000271442 1 0 BeFree
Non-alcoholic Fatty Liver Disease 0.000271442 1 0 BeFree
Secondary malignant neoplasm of liver 0.000271442 1 0 BeFree
Thyroid carcinoma 0.000271442 1 0 BeFree
Malignant Glioma 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
precancerous lesions 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Desmoplastic fibroblastoma 0.000271442 1 0 BeFree
Carcinoma of urinary bladder, superficial 0.000271442 1 0 BeFree
Renal carcinoma 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Gardner fibroma 0.000271442 1 0 BeFree
Nasopharyngeal carcinoma 0.000271442 1 0 BeFree
Deficiency of glucose-6-phosphate dehydrogenase 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

没有相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2