FMR1(fragile X mental retardation 1) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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Xq27.3
基因染色体位置图

The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene. [provided by RefSeq, May 2010]

[中文简述(自动翻译):]  由该基因编码的蛋白质结合的RNA,并与多聚核糖体相关联。所编码的蛋白质可在mRNA的贩卖从细胞核至细胞质的参与。 5‘UTR一个三核苷酸重复序列(CGG)通常在6-53份发现,而是扩大到55-230重复是脆性X综合征的原因。的三核苷酸重复的扩张也可能会导致过早的卵巢功能衰竭(POF1)的一种形式。编码不同蛋白同种型和存在于不同的细胞位置的多个可变剪接转录物变体已被用于这个基因说明。 [由RefSeq的,2010年5月提供]

FMR1基因的碱基序列:[NCBI]
FMR1基因的碱基突变:           显示全部snp
rs782817388       rs782810868       rs782809564       rs782809028       rs782803443       rs782802789       rs782802784       rs782798947       rs782792994       rs782794431       rs782791888       rs782789984       rs782791326       rs782789255       rs782786997       rs782788468       rs782785405       rs782782102       rs782783430       rs782781073       rs782780784       rs782777770       rs782778170       rs782780329       rs782774672       rs782770998       rs782767543       rs782764271       rs782760083       rs782763509       rs782759579       rs782755722       rs782755446       rs782753583       rs782751337       rs782752230       rs782750259      
rs782748949       rs782748743       rs782747591       rs782746869       rs782743301       rs782738200       rs782740291       rs782729986       rs782729710       rs782729102       rs782728224       rs782727464       rs782725766       rs782721527       rs782720659       rs782719335       rs782720052       rs782717020       rs782715138       rs782716936       rs782711774       rs782710801       rs782705051       rs782710584       rs782701739       rs782696616       rs782699102       rs782696345       rs782694379       rs782688993       rs782690208       rs782694168       rs782684689       rs782682355       rs782683523       rs782679835       rs782676548       rs782678826       rs782679317       rs782676064       rs782674880       rs782671116       rs782673182       rs782669890       rs782667205       rs782665407       rs782666443       rs782664432       rs782665287       rs782663449       rs782660799       rs782659708       rs782656674       rs782652730       rs782651077       rs782651740       rs782650991       rs782649681       rs782646685       rs782644279       rs782641378       rs782641601       rs782639149       rs782637451       rs782632872       rs782637135       rs782630605       rs782632430       rs782625391       rs782630082       rs782630349       rs782622799       rs782621753       rs782618040       rs782617656       rs782612824       rs782612460       rs782603869       rs782608069       rs782601389       rs782602321       rs782600159       rs782599029       rs782597880       rs782594449       rs782596604       rs782591214       rs782591089       rs782591190       rs782590543       rs782590788       rs782589532       rs782586040       rs782586108       rs782586675       rs782585383       rs782582874       rs782580797       rs782570671       rs782569052       rs782569247       rs782565896       rs782563625       rs782564832       rs782562897       rs782560187       rs782556646       rs782555354       rs782550780       rs782551523       rs782547889       rs782544542       rs782544831       rs782540168       rs782539364       rs782532137       rs782531620       rs782530601       rs782529607       rs782530140       rs782525026       rs782522813       rs782522885       rs782519634       rs782522203       rs782518319       rs782516655       rs782515465       rs782514882       rs782514950       rs782514586       rs782513693       rs782508117       rs782506417       rs782503252       rs782505258       rs782501975       rs782496769       rs782496029       rs782494714       rs782494548       rs782494131       rs782492689       rs782485814       rs782491106       rs782482776       rs782483148       rs782484339       rs782479098       rs782479597       rs782476418       rs782477710       rs782474954       rs782472011       rs782474021       rs782470399       rs782469507       rs782467819       rs782468641       rs782464113       rs782462064       rs782461262       rs782456938       rs782449484       rs782453023       rs782455986       rs782448298       rs782440586       rs782446757       rs782436926       rs782438699       rs782439456       rs782434875       rs782434905       rs782435424       rs782433104       rs782426996       rs782428161       rs782429224       rs782430494       rs782430559       rs782430658       rs782426165       rs782426475       rs782421098       rs782421246       rs782422077       rs782422703       rs782425569       rs782425852       rs782419598       rs782419872       rs782415147       rs782413283       rs782412295       rs782412945       rs782402980       rs782407009       rs782410961       rs782402226       rs782393400       rs782394506       rs782399259       rs782390207       rs782390448       rs782392454       rs782386339       rs782388446       rs782390188       rs782386085       rs782383203       rs782377065       rs782382560       rs782382658       rs782375663       rs782367211       rs782373736       rs782366653       rs782362046       rs782363864       rs782361785       rs782358545       rs782356861       rs782355694       rs782355760       rs782356635       rs782353782       rs782347983       rs782343048       rs782340472       rs782340568       rs782339890       rs782338857       rs782338899       rs782338221       rs782334963       rs782332494       rs782333371       rs782326789       rs782331869       rs782325167       rs782325234       rs782322977       rs782321459       rs782322890       rs782320232       rs782316492       rs782313985       rs782302981       rs782308259       rs782298459       rs782302816       rs782296772       rs782293900       rs782296411       rs782293684       rs782293202       rs782290754       rs782292811       rs782289520       rs782287500       rs782284934       rs782287372       rs782284837       rs782283431       rs782280999       rs782283130       rs782278808       rs782271433       rs782275919       rs782277375       rs782270889       rs782265090       rs782265632       rs782265911       rs782263277       rs782261775       rs782260387       rs782260774       rs782261270       rs782259520       rs782258926       rs782258757       rs782257841       rs782257390       rs782255859       rs782255100       rs782249227       rs782253006       rs782244397       rs782244363       rs782243759       rs782233272       rs782239059       rs782241056       rs782232512       rs782232311       rs782232249       rs782232058       rs782231315       rs782230255       rs782222992       rs782229219       rs782222851       rs782222368       rs782219926       rs782217705       rs782218574       rs782211175       rs782214283       rs782215947       rs782208740       rs782208456       rs782202548       rs782203628       rs782205810       rs782200660       rs782197007       rs782191544       rs782194402       rs782195120       rs782188241       rs782187286       rs782185078       rs782179825       rs782183190       rs782184615       rs782179147       rs782171369       rs782174937       rs782170936       rs782168621       rs782169223       rs782168275       rs782165786       rs782166122       rs782163405       rs782160649       rs782162376       rs782163090       rs782157694       rs782158375       rs782155167       rs782156891       rs782154957       rs782147939       rs782150817       rs782151729       rs782142242       rs782142501       rs782140032       rs782137332       rs782137100       rs782133807       rs782133154       rs782133722       rs782133103       rs782130500       rs782132151       rs782128808       rs782127209       rs782124550       rs782125659       rs782122048       rs782115827       rs782116567       rs782118510       rs782112975       rs782112185       rs782111442       rs782108938       rs782101918       rs782101551       rs782099660       rs782100174       rs782098551       rs782097137       rs782092632       rs782091753       rs782090869       rs782089493       rs782089884       rs782090500       rs782082298       rs782081553       rs782077714       rs782080368       rs782077566       rs782076400       rs782071756       rs782073569       rs782070342       rs782070708       rs782068207       rs782063900       rs782064948       rs782063588       rs782059448       rs782059731       rs782060324       rs782058946       rs782049946       rs782047438       rs782046055       rs782042786       rs782043948       rs782039470       rs782041975       rs782037681       rs782035908       rs782033216       rs782033057       rs782031356       rs782032807       rs782026256       rs782027594       rs782023090       rs782022387       rs782016744       rs782016069       rs782014930       rs782013865       rs782014719       rs782013598       rs782009484       rs782012600       rs782009400       rs782008600       rs782005008       rs782005079       rs782004538       rs782003519       rs782004372       rs781999118       rs781999013       rs781994603       rs781998340       rs781990963       rs781980854       rs781983693       rs781988521       rs781977593       rs781977383       rs781974685       rs781972179       rs781968725       rs781971022       rs781964867       rs781967289       rs781963400       rs781962462       rs781962133       rs781961988       rs781960795       rs781953113       rs781936295       rs781941669       rs781942813       rs781935462       rs781935092       rs781934194       rs781933453       rs781929666       rs781931767       rs781924538       rs781925917       rs781923784       rs781923644       rs781919982       rs781921361       rs781918121       rs781919601       rs781917851       rs781917691       rs781916978       rs781914097       rs781910579       rs781908764       rs781905700       rs781904156       rs781903736       rs781903920       rs781903112       rs781901925       rs781902319       rs781897232       rs781896910       rs781893340       rs781895870       rs781892436       rs781892909       rs781888657       rs781888782       rs781889839       rs781883559       rs781877617       rs781877186       rs781877158       rs781876746       rs781873697       rs781868887       rs781867453       rs781868575       rs781866021       rs781862122       rs781865762       rs781862015       rs781860089       rs781858239       rs781858260       rs781859782       rs781857570       rs781853998       rs781855563       rs781849302       rs781846007       rs781849284       rs781845856       rs781838130       rs781835336       rs781833500       rs781832136       rs781832896       rs781830664       rs781829403       rs781828790       rs781828844       rs781827326       rs781827082       rs781824814       rs781823392       rs781819933       rs781820595       rs781817515       rs781818343       rs781816128       rs781812692       rs781809057       rs781810881       rs781805235       rs781806502       rs781804817       rs781804533       rs781804261       rs781801964       rs781797563       rs781801306       rs781792903       rs781795108       rs781790587       rs781788952       rs781788937       rs781784498       rs781784951       rs781784284       rs572488461       rs587780338       rs571818405       rs568651143       rs567662098       rs557233085       rs549441216       rs548035697       rs547257947       rs545483132       rs539811597       rs539224955       rs539036839       rs377682030       rs530989099       rs376856715       rs376725656       rs376794313       rs376406395       rs375991236       rs376113075       rs375873377       rs375982343       rs375742707       rs375814197       rs374651279       rs375014322       rs375330839       rs374008687       rs374108589       rs373823576       rs372981558       rs373400476       rs373555716       rs372916945       rs372396040       rs372019441       rs372138591       rs372394999       rs371495007       rs371420910       rs371477528       rs371379297       rs370873100       rs370079718       rs370267607       rs370567479       rs369902962       rs369585221       rs368783198       rs369023505       rs368702689       rs368432261       rs368413161       rs367795320       rs201939954       rs202080813       rs201937090       rs201515036       rs201041299       rs200930415       rs200725985       rs200602925       rs200572157       rs200465514       rs200458654       rs200163413       rs200381008       rs200138498       rs199745848       rs199845941       rs199683411       rs199566090       rs193100475       rs193074070       rs193052026       rs192680036       rs192653907       rs192629288       rs192460880       rs192425259       rs192361542       rs191941795       rs191928768       rs191374378       rs191290706       rs191232926       rs191137527       rs191072863       rs190754519       rs190483443       rs190383146       rs190203528       rs190129148       rs189834092       rs189643239       rs189624181       rs189599737       rs189536386       rs189377879       rs189064748       rs188815693       rs188525015       rs188423334       rs188414110       rs188285746       rs188136224       rs187838421       rs187675969       rs187565603       rs187559657       rs187535595       rs187302252       rs187242457       rs187016127       rs186984505       rs186789410       rs186344906       rs186264152       rs186038867       rs185968594       rs185886633       rs185868799       rs185807396       rs185366584       rs185310740       rs185206946       rs185026643       rs184987604       rs184830498       rs184797477       rs184776596       rs184437820       rs184420507       rs184275787       rs183831845       rs183771821       rs183745963       rs183627084       rs183534765       rs183433512       rs183415878       rs183130936       rs183087450       rs182865644       rs182830086       rs182803885       rs182251747       rs182245390       rs182056341       rs181863081       rs181856740       rs181643710       rs181587058       rs181503214       rs181459128       rs181431219       rs181320662       rs181127333       rs181106620       rs180714563       rs151285811       rs150912656       rs150884427       rs150724379       rs150405928       rs149678734       rs149606936       rs148872586       rs149435742       rs148602524       rs148216485       rs147864235       rs147478734       rs147405152       rs147296761       rs146297962       rs145953697       rs145936124       rs145793653       rs145670599       rs144660432       rs144476467       rs144392181       rs144100889       rs143889976       rs143655724       rs143611778       rs143161663       rs143515118       rs142857682       rs142847092       rs142399840       rs142391209       rs142052787       rs141552174       rs141464173       rs140188147       rs140178350       rs139801134       rs140123351       rs139271518       rs139029212       rs138279248       rs138792184       rs138084570       rs137958767       rs113925155       rs113641909       rs113627441       rs113637030       rs113550657       rs113327806       rs112763380       rs112787441       rs111870942       rs111659920       rs111507087       rs111504232       rs80358324       rs76581450       rs79298659       rs73606790       rs73606788       rs73606781       rs73606778       rs73247516       rs60352434       rs45540244       rs36122297       rs41311668       rs12837623       rs12156753       rs12012926       rs11798323       rs11390934       rs11361700       rs11342854       rs11293471       rs7885132       rs7878418       rs7054612       rs7052022       rs5951855       rs5904816       rs5904815       rs5904814       rs5904651       rs5904650       rs4824233       rs4824232       rs2187601       rs3737554       rs1805425       rs1805424       rs1051719       rs1051722       rs29300       rs29299       rs29292       rs29291       rs29290       rs29289       rs29288       rs29287       rs29286       rs29285       rs29284       rs29283       rs29282       rs29281       rs29280       rs29279       rs29278       rs29277       rs25731       rs25729       rs25730       rs25728       rs25724       rs25723       rs25722       rs25721       rs25720       rs25719       rs25718       rs25717       rs25715       rs25714       rs25713       rs25712       rs25710       rs25709       rs25708       rs25707       rs25706       rs25704       rs25703       rs25702       rs25701       rs25700       rs25699       rs25698       rs782816797       rs782810936       rs782802994       rs782797402       rs782792155       rs782771578       rs782768949       rs782764826       rs782763703       rs782756347       rs782756294       rs782755140       rs782751758       rs782745762       rs782736451       rs782728214       rs782732707       rs782726338       rs782726193       rs782725702       rs782721471       rs782711960       rs782686026       rs782680563       rs782679255       rs782667590       rs782661589       rs782653574       rs782652335       rs782642646       rs782641960       rs782639729       rs782618434       rs782618062       rs782614202       rs782612227       rs782607774       rs782607479       rs782606034       rs782604181       rs782593700       rs782575157       rs782569511       rs782567477       rs782561489       rs782559858       rs782559452       rs782552655       rs782539753       rs782537223       rs782534489       rs782533226       rs782530523       rs782529101       rs782519571       rs782515227       rs782499922       rs782496652       rs782499537       rs782496416       rs782493322       rs782462298       rs782460384       rs782455518       rs782455000       rs782446756       rs782446137       rs782431742       rs782431519       rs782425528       rs782427673       rs782414544       rs782415153       rs782395504       rs782412079       rs782386709       rs782381373       rs782377522       rs782368032       rs782376980       rs782364335       rs782360231       rs782362446       rs782350419       rs782350674       rs782349211       rs782349078       rs782343393       rs782342173       rs782329325       rs782341743       rs782327970       rs782316864       rs782320349       rs782307232       rs782303727       rs782294981       rs782299535       rs782275916       rs782277768       rs782273914       rs782269108       rs782267566       rs782264973       rs782246598       rs782233715       rs782229478       rs782216982       rs782214447       rs782193161       rs782201022       rs782202125       rs782192411       rs782184011       rs782189603       rs782173345       rs782155519       rs782149363       rs782146520       rs782145489       rs782124990       rs782128772       rs782123158       rs782119834       rs782108065       rs782116443       rs782100319       rs782088881       rs782084110       rs782082473       rs782081139       rs782080490       rs782071349       rs782070544       rs782061895       rs782055597       rs782054175       rs782053473       rs782052128       rs782048023       rs782046961       rs782042669       rs782039611       rs782035139       rs782022364       rs782018260       rs782016669       rs782013130       rs782008399       rs782004243       rs781993938       rs781989839       rs781976701       rs781971380       rs781957880       rs781955610       rs781949670       rs781949021       rs781942661       rs781942540       rs781939792       rs781939219       rs781934113       rs781928912       rs781924236       rs781907443       rs781902864       rs781890195       rs781887597       rs781872305       rs781872049       rs781870205       rs781868385       rs781863877       rs781840329       rs781848103       rs781833234       rs781831431       rs781826593       rs781820762       rs781818537       rs781818630       rs781810680       rs781795787       rs781794455       rs781793583       rs781792641       rs781783361       rs570020094       rs568604430       rs563165971       rs540853502       rs537466419       rs376696232       rs376503974       rs371928026       rs373183831       rs202221941       rs202144557       rs200904100       rs200122099       rs193237598       rs192512502       rs192292142       rs192215222       rs192032354       rs191789133       rs191463645       rs191283058       rs191064825       rs191019272       rs190926259       rs190746061       rs190441718       rs190203242       rs189411555       rs189334459       rs189103352       rs188751686       rs188564603       rs188371014       rs187847594       rs187777866       rs187671210       rs187571664       rs187031422       rs187005180       rs186929198       rs186087580       rs186059683       rs186030977       rs185976434       rs185908006       rs185667977       rs185356050       rs184627591       rs184538508       rs184329349       rs184455659       rs184269569       rs184073960       rs183760491       rs183138505       rs182929833       rs182854568       rs182363306       rs182322678       rs182074719       rs182047172       rs181422922       rs181357710       rs181247203       rs181114623       rs180708595       rs150973688       rs150243717       rs149524570       rs148989821       rs148338484       rs147806096       rs147776324       rs147756929       rs147401708       rs146924565       rs146302130       rs145821103       rs144395944       rs144062911       rs143346252       rs141796490       rs141479979       rs141277647       rs141166202       rs141098913       rs139484594       rs138362974       rs113401321       rs138302803       rs113237999       rs113111897       rs113083520       rs111921256       rs111485627       rs80358323       rs76469853       rs73606774       rs73606770       rs73606765       rs61454069       rs57870272       rs35739145       rs12388933       rs12013181       rs10521868       rs6626955       rs5951751       rs4824257       rs1805423       rs1805422       rs1805421       rs1805420       rs1270096       rs1270095       rs1270094       rs1270093       rs1270092       rs1270091       rs971000       rs29297       rs29296       rs29295       rs29294       rs28902       rs28901       rs28900       rs25727       rs25726       rs25725       rs4949      

FMR1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GATCTAGATGAAGATACCTGCAC
58
TCTTCAACCCTACTAAGTTCCT
58
TGTCCATCAATGAAGTCACC
58
CAAGCTGCCTTGAACTCTC
59
AATGGGTCGAGGTAGTAGAC
58
GTCTCTGTGGTCAGATTCTG
58
CAAGAATTGACCACCTCGTG
59
GGAATACACCTCAACTTCATCAC
60
TGTCCATCAATGAAGTCACCT
60
CAAGCTGCCTTGAACTCTC
59
TGGATCCCTTCAGATCAGAG
58
CCTTCACTGGAGGTATTCTG
57
GATCTAGATGAAGATACCTGCA
57
ATCTTCAACCCTACTAAGTTCC
57
TTGTGGGAACAAAGGACAG
58
CAATCTGTCGCAACTGCTC
60
GCTTTCTACAAGCATTGGGA
59
ATTGTGATTTGGTGCCGAC
59
CAAGGGTTGGACCTAATGC
59
CCACTAACACCCTCTGGAC
59
      尚未收录相关数据

FMR1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

FMR1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0003723
A0A087WWR6(UniProtKB)
IEA
GO:0003723
A0A087WXC0(UniProtKB)
IEA
GO:0003723
A0A087WXI3(UniProtKB)
IEA
GO:0003723
A0A087WY29(UniProtKB)
IEA
GO:0003723
A8MQB8(UniProtKB)
IEA
GO:0005737
A8MQB8(UniProtKB)
IDA
GO:0003723
G3V0J0(UniProtKB)
IEA
GO:0005737
G3V0J0(UniProtKB)
IDA
GO:0003723
G8JLE9(UniProtKB)
IEA
GO:0000381
Q06787(UniProtKB)
IDA
GO:0002092
Q06787(UniProtKB)
IDA
GO:0002151
Q06787(UniProtKB)
IDA
GO:0002151
Q06787(UniProtKB)
IDA
GO:0003682
Q06787(UniProtKB)
ISS
GO:0003723
Q06787(UniProtKB)
IDA
GO:0003729
Q06787(UniProtKB)
IDA
GO:0003729
Q06787(UniProtKB)
IDA
GO:0003729
Q06787(UniProtKB)
IDA
GO:0003730
Q06787(UniProtKB)
IDA
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005515
Q06787(UniProtKB)
IPI
GO:0005634
Q06787(UniProtKB)
ISS
GO:0005634
Q06787(UniProtKB)
IDA
GO:0005634
Q06787(UniProtKB)
IDA
GO:0005634
Q06787(UniProtKB)
IDA
GO:0005654
Q06787(UniProtKB)
IDA
GO:0005694
Q06787(UniProtKB)
ISS
GO:0005730
Q06787(UniProtKB)
TAS
GO:0005730
Q06787(UniProtKB)
IDA
GO:0005730
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
TAS
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005737
Q06787(UniProtKB)
IDA
GO:0005844
Q06787(UniProtKB)
ISS
GO:0005844
Q06787(UniProtKB)
ISS
GO:0005844
Q06787(UniProtKB)
IDA
GO:0005844
Q06787(UniProtKB)
IDA
GO:0005844
Q06787(UniProtKB)
IDA
GO:0005844
Q06787(UniProtKB)
IDA
GO:0005845
Q06787(UniProtKB)
ISS
GO:0006974
Q06787(UniProtKB)
IDA
GO:0007215
Q06787(UniProtKB)
ISS
GO:0007215
Q06787(UniProtKB)
ISS
GO:0008017
Q06787(UniProtKB)
ISS
GO:0008266
Q06787(UniProtKB)
IDA
GO:0008266
Q06787(UniProtKB)
IDA
GO:0008266
Q06787(UniProtKB)
IDA
GO:0008266
Q06787(UniProtKB)
IDA
GO:0010369
Q06787(UniProtKB)
ISS
GO:0014069
Q06787(UniProtKB)
ISS
GO:0015030
Q06787(UniProtKB)
IDA
GO:0015030
Q06787(UniProtKB)
IDA
GO:0016020
Q06787(UniProtKB)
IDA
GO:0017148
Q06787(UniProtKB)
IBA
GO:0019034
Q06787(UniProtKB)
IDA
GO:0019897
Q06787(UniProtKB)
ISS
GO:0030371
Q06787(UniProtKB)
IDA
GO:0030424
Q06787(UniProtKB)
ISS
GO:0030425
Q06787(UniProtKB)
ISS
GO:0030425
Q06787(UniProtKB)
ISS
GO:0030426
Q06787(UniProtKB)
IDA
GO:0030529
Q06787(UniProtKB)
IDA
GO:0031369
Q06787(UniProtKB)
IPI
GO:0032433
Q06787(UniProtKB)
ISS
GO:0033129
Q06787(UniProtKB)
IDA
GO:0033592
Q06787(UniProtKB)
IDA
GO:0034046
Q06787(UniProtKB)
IDA
GO:0034046
Q06787(UniProtKB)
IDA
GO:0034046
Q06787(UniProtKB)
IDA
GO:0034644
Q06787(UniProtKB)
ISS
GO:0035064
Q06787(UniProtKB)
IDA
GO:0035197
Q06787(UniProtKB)
IDA
GO:0035198
Q06787(UniProtKB)
IDA
GO:0035613
Q06787(UniProtKB)
IDA
GO:0035613
Q06787(UniProtKB)
IDA
GO:0036464
Q06787(UniProtKB)
IDA
GO:0036464
Q06787(UniProtKB)
IDA
GO:0036464
Q06787(UniProtKB)
IDA
GO:0042802
Q06787(UniProtKB)
IDA
GO:0042803
Q06787(UniProtKB)
IDA
GO:0042995
Q06787(UniProtKB)
IDA
GO:0043005
Q06787(UniProtKB)
IDA
GO:0043022
Q06787(UniProtKB)
IPI
GO:0043197
Q06787(UniProtKB)
ISS
GO:0043197
Q06787(UniProtKB)
ISS
GO:0043198
Q06787(UniProtKB)
IEA
GO:0043204
Q06787(UniProtKB)
ISS
GO:0043204
Q06787(UniProtKB)
IDA
GO:0043204
Q06787(UniProtKB)
IDA
GO:0043488
Q06787(UniProtKB)
ISS
GO:0043679
Q06787(UniProtKB)
ISS
GO:0044325
Q06787(UniProtKB)
IPI
GO:0044822
Q06787(UniProtKB)
IDA
GO:0044822
Q06787(UniProtKB)
IDA
GO:0044830
Q06787(UniProtKB)
IMP
GO:0045202
Q06787(UniProtKB)
ISS
GO:0045502
Q06787(UniProtKB)
ISS
GO:0045727
Q06787(UniProtKB)
IDA
GO:0045727
Q06787(UniProtKB)
IDA
GO:0045947
Q06787(UniProtKB)
ISS
GO:0046928
Q06787(UniProtKB)
ISS
GO:0046982
Q06787(UniProtKB)
IDA
GO:0048027
Q06787(UniProtKB)
IDA
GO:0048471
Q06787(UniProtKB)
IDA
GO:0051028
Q06787(UniProtKB)
ISS
GO:0051489
Q06787(UniProtKB)
IDA
GO:0051491
Q06787(UniProtKB)
ISS
GO:0060964
Q06787(UniProtKB)
IMP
GO:0060998
Q06787(UniProtKB)
IDA
GO:0060999
Q06787(UniProtKB)
ISS
GO:0071598
Q06787(UniProtKB)
ISS
GO:0072711
Q06787(UniProtKB)
ISS
GO:0097386
Q06787(UniProtKB)
ISS
GO:0098586
Q06787(UniProtKB)
IDA
GO:0098793
Q06787(UniProtKB)
ISS
GO:0098794
Q06787(UniProtKB)
ISS
GO:0098908
Q06787(UniProtKB)
IDA
GO:1900453
Q06787(UniProtKB)
ISS
GO:1901254
Q06787(UniProtKB)
IMP
GO:1901386
Q06787(UniProtKB)
ISS
GO:1901800
Q06787(UniProtKB)
ISS
GO:1902416
Q06787(UniProtKB)
IDA
GO:1902737
Q06787(UniProtKB)
ISS
GO:1902737
Q06787(UniProtKB)
ISS
GO:1990812
Q06787(UniProtKB)
ISS
GO:1990825
Q06787(UniProtKB)
IDA
GO:1990825
Q06787(UniProtKB)
IDA
GO:1990904
Q06787(UniProtKB)
IDA
GO:2000301
Q06787(UniProtKB)
ISS
GO:2000637
Q06787(UniProtKB)
IDA
GO:2000766
Q06787(UniProtKB)
ISS
GO:2001022
Q06787(UniProtKB)
IDA
GO:0032797
Q06787(UniProtKB)
IDA
GO:0042788
Q06787(UniProtKB)
TAS
GO:0003723
Q8IXW7(UniProtKB)
IEA
GO:0003723
R9WNI0(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控FMR1基因的相关microRNA:      显示全部miRNA


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Fragile X Syndrome 0.747499467 557 2 BeFree_CLINVAR_CTD_human_GAD_LHGDN_MGD_ORPHANET_UNIPROT
FRAGILE X TREMOR/ATAXIA SYNDROME 0.360292949 131 0 BeFree_CLINVAR_CTD_human_GAD_MGD
Autistic Disorder 0.21695888 36 0 BeFree_CTD_human_GAD_LHGDN_MGD
Ovarian Failure, Premature 0.187313836 77 0 BeFree_CTD_human_GAD_LHGDN
Intellectual Disability 0.14340359 33 0 BeFree_CTD_human_LHGDN
FRAXA Syndrome 0.122442977 9 0 BeFree_ORPHANET
Congenital Abnormality 0.121085767 5 0 BeFree_CTD_human
Cognition Disorders 0.120814326 4 0 BeFree_CTD_human
Primary Ovarian Insufficiency, Fragile X-Associated 0.120271442 2 0 BeFree_CTD_human
Gonadal Dysgenesis 0.12 1 0 CTD_human
Facies 0.12 1 0 CTD_human
Craniofacial Abnormalities 0.12 2 0 CTD_human
CHROMOSOME Xq27.3-q28 DUPLICATION SYNDROME 0.12 0 0 ORPHANET
Mental Retardation 0.042659981 133 1 BeFree_GAD
Tremor 0.024165715 21 0 BeFree_GAD_LHGDN
Ataxia 0.023698776 24 0 BeFree_GAD_LHGDN
Parkinson Disease 0.021279544 9 0 BeFree_GAD_LHGDN
Premature Menopause 0.012681823 38 0 BeFree_GAD
Neurodegenerative Disorders 0.010857675 40 0 BeFree
Parkinsonian Disorders 0.010606096 19 0 BeFree_LHGDN
Ataxia, Spinocerebellar 0.008458305 7 0 BeFree_GAD
Female infertility 0.007101096 3 0 GAD
Disorder of endocrine ovary 0.006905599 9 0 BeFree_GAD
Dementia 0.00680591 7 0 BeFree_LHGDN
Impaired cognition 0.004885954 18 0 BeFree
Movement Disorders 0.004267125 8 0 BeFree_GAD
Turner Syndrome 0.004071628 15 0 BeFree
Mental disorders 0.003724241 6 0 BeFree_GAD
Cerebellar Diseases 0.003267234 2 0 BeFree_LHGDN
Atrial Septal Defects 0.003257302 12 2 BeFree
Mental handicap 0.003257302 12 0 BeFree
Autism Spectrum Disorders 0.002985861 11 0 BeFree
Essential Tremor 0.002909916 2 0 BeFree_GAD
Asthma 0.00272435 1 0 LHGDN
Abnormal mental state 0.002714419 10 0 BeFree
Ovarian failure 0.002714419 10 0 BeFree
Mental Retardation, X-Linked 0.002714419 10 0 BeFree
Anxiety Disorders 0.002442977 9 0 BeFree
Epilepsy 0.002442977 9 0 BeFree
Action Tremor 0.002442977 9 0 BeFree
Hypergonadotropic Ovarian Failure, X-Linked 0.002442977 9 0 BeFree
Diminished ovarian reserve 0.002442977 9 0 BeFree
Ataxia Telangiectasia 0.002367032 1 0 GAD
Huntington Disease 0.002367032 1 0 GAD
Ovarian Diseases 0.002367032 1 0 GAD
Spinocerebellar Degeneration 0.002367032 1 0 GAD
Genomic Instability 0.002367032 1 0 GAD
Seizures 0.001900093 7 0 BeFree
Developmental delay (disorder) 0.001900093 7 0 BeFree
Ovarian Insufficiency 0.001900093 7 0 BeFree
Developmental Disabilities 0.001628651 6 0 BeFree
Exanthema 0.001628651 6 0 BeFree
Mild Mental Retardation 0.001628651 6 0 BeFree
Learning Disabilities 0.001628651 6 0 BeFree
Spots on skin 0.001628651 6 0 BeFree
Macroorchidism 0.001628651 6 0 BeFree
Presenile dementia 0.001357209 5 0 BeFree
nervous system disorder 0.001357209 5 0 BeFree
Schizophrenia 0.001357209 5 0 BeFree
Neurologic Symptoms 0.001357209 5 0 BeFree
Neurodevelopmental Disorders 0.001357209 5 0 BeFree
Autoimmune Diseases 0.001085767 4 0 BeFree
Malignant neoplasm of breast 0.001085767 4 0 BeFree
Mental Depression 0.001085767 4 0 BeFree
Depressive disorder 0.001085767 4 0 BeFree
HIV Infections 0.001085767 4 0 BeFree
Prader-Willi Syndrome 0.001085767 4 0 BeFree
Memory impairment 0.001085767 4 0 BeFree
Fragile X chromosome 0.001085767 4 0 BeFree
Breast Carcinoma 0.001085767 4 0 BeFree
Attention deficit hyperactivity disorder 0.001085767 4 0 BeFree
Fibromyalgia 0.000814326 3 0 BeFree
Myotonic Dystrophy 0.000814326 3 0 BeFree
Shy-Drager Syndrome 0.000814326 3 0 BeFree
Unipolar Depression 0.000814326 3 0 BeFree
Psychological symptom 0.000814326 3 0 BeFree
Multiple System Atrophy 0.000814326 3 0 BeFree
Congenital Myotonic Dystrophy 0.000814326 3 0 BeFree
Social fear 0.000814326 3 0 BeFree
Autistic behavior 0.000814326 3 0 BeFree
Major Depressive Disorder 0.000814326 3 0 BeFree
Executive dysfunction 0.000814326 3 0 BeFree
Learning disabled 0.000814326 3 0 BeFree
Amenorrhea 0.000542884 2 0 BeFree
Cerebellar Ataxia 0.000542884 2 0 BeFree
Congenital chromosomal disease 0.000542884 2 0 BeFree
Metabolic Diseases 0.000542884 2 0 BeFree
Moderate mental retardation (I.Q. 35-49) 0.000542884 2 0 BeFree
Mucopolysaccharidosis II 0.000542884 2 0 BeFree
Cerebral atrophy 0.000542884 2 0 BeFree
brain dysfunction 0.000542884 2 0 BeFree
Congenital anomaly of face 0.000542884 2 0 BeFree
Spastic syndrome 0.000542884 2 0 BeFree
Motor symptoms 0.000542884 2 0 BeFree
audiogenic seizure 0.000542884 2 0 BeFree
FRAXE Syndrome 0.000542884 2 0 BeFree
Dentatorubral-Pallidoluysian Atrophy 0.000542884 2 0 BeFree
Gait Ataxia 0.000542884 2 0 BeFree
Dysmorphism 0.000542884 2 0 BeFree
COGNITIVE FUNCTION 1, SOCIAL 0.000542884 2 0 BeFree
Alzheimer's Disease 0.000271442 1 0 BeFree
Amyotrophic Lateral Sclerosis 0.000271442 1 0 BeFree
Ataxias, Hereditary 0.000271442 1 0 BeFree
Avoidant Personality Disorder 0.000271442 1 0 BeFree
Behavior Disorders 0.000271442 1 0 BeFree
Bipolar Disorder 0.000271442 1 0 BeFree
Down Syndrome 0.000271442 1 0 BeFree
Friedreich Ataxia 0.000271442 1 0 BeFree
Hypothyroidism 0.000271442 1 0 BeFree
Ichthyoses 0.000271442 1 0 BeFree
Congenital ichthyosis 0.000271442 1 0 BeFree
Klinefelter Syndrome 0.000271442 1 0 BeFree
Language Delay 0.000271442 1 0 BeFree
Liver diseases 0.000271442 1 1 BeFree
Lung Neoplasms 0.000271442 1 0 BeFree
Machado-Joseph Disease 0.000271442 1 0 BeFree
Multiple Sclerosis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Pain 0.000271442 1 0 BeFree
Phobia, Social 0.000271442 1 0 BeFree
Polycystic Ovary Syndrome 0.000271442 1 0 BeFree
Sleep disturbances 0.000271442 1 0 BeFree
Stress, Psychological 0.000271442 1 0 BeFree
Cerebrovascular accident 0.000271442 1 0 BeFree
Thyroid Diseases 0.000271442 1 0 BeFree
Tuberous Sclerosis 0.000271442 1 0 BeFree
Ichthyosis, X-Linked 0.000271442 1 0 BeFree
Migraine Disorders 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Secondary physiologic amenorrhea 0.000271442 1 0 BeFree
Psychiatric symptom 0.000271442 1 0 BeFree
Bradykinesia 0.000271442 1 0 BeFree
Pick Disease of the Brain 0.000271442 1 0 BeFree
Frontotemporal dementia 0.000271442 1 0 BeFree
Mixed anxiety and depressive disorder 0.000271442 1 0 BeFree
Deficiency of testosterone biosynthesis 0.000271442 1 0 BeFree
Hematologic Neoplasms 0.000271442 1 0 BeFree
Cerebellar Ataxia, Late Onset 0.000271442 1 0 BeFree
Inattention 0.000271442 1 0 BeFree
Klinefelter's syndrome - male with more than two X chromosomes 0.000271442 1 0 BeFree
Developmental symptoms 0.000271442 1 0 BeFree
Dyslexia 0.000271442 1 0 BeFree
Mood Disorders 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Leukemogenesis 0.000271442 1 0 BeFree
Mental impairment 0.000271442 1 0 BeFree
Psychoticism 0.000271442 1 0 BeFree
Dyssomnias 0.000271442 1 0 BeFree
Spinocerebellar Ataxia Type 1 0.000271442 1 0 BeFree
Smith-Magenis syndrome 0.000271442 1 0 BeFree
AICARDI-GOUTIERES SYNDROME 1 0.000271442 1 0 BeFree
Sleep Disorders 0.000271442 1 0 BeFree
Becker Muscular Dystrophy 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Degenerative disorder 0.000271442 1 0 BeFree
Takotsubo Cardiomyopathy 0.000271442 1 0 BeFree
Opitz-G syndrome, type 2 0.000271442 1 0 BeFree
Bulbo-Spinal Atrophy, X-Linked 0.000271442 1 0 BeFree
Placental Steroid Sulfatase Deficiency 0.000271442 1 0 BeFree
Mental Retardation, X-Linked 1 0.000271442 1 0 BeFree
Triple Negative Breast Neoplasms 0.000271442 1 0 BeFree
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