FMOD(fibromodulin) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

1q32
基因染色体位置图

基因简述

基因简述

Fibromodulin belongs to the family of small interstitial proteoglycans. The encoded protein possesses a central region containing leucine-rich repeats with 4 keratan sulfate chains, flanked by terminal domains containing disulphide bonds. Owing to the interaction with type I and type II collagen fibrils and in vitro inhibition of fibrillogenesis, the encoded protein may play a role in the assembly of extracellular matrix. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix. Sequence variations in this gene may be associated with the pathogenesis of high myopia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]

[中文简述(自动翻译):]  纤维调节属于家庭小间质蛋白多糖。所编码的蛋白质具有含有与硫酸角质素4链，通过含有二硫键末端结构域侧翼富含亮氨酸的重复序列的中央区域。由于与I型和II型胶原纤维和原纤维的体外抑制的相互作用，所编码蛋白可以起到细胞外基质的装配中起作用。它也可以通过隔离的TGF-β到细胞外基质调节TGF-β的活性。该基因序列变异可能与高度近视眼的发病有关。选择性剪接结果在多个抄本变形。 [由RefSeq的，2013年6月提供]

OMIM数据库中对FMOD基因的介绍     Wikipedia数据库中对FMOD基因的介绍

基因序列

基因序列

FMOD基因的碱基序列：[NCBI]

基因突变

基因突变

FMOD基因的碱基突变：           显示全部snp
rs4605       rs7208       rs883151       rs1126423       rs1891180       rs2105309       rs2886220       rs3051538       rs3738019       rs3738020       rs3738021       rs3738022       rs3766912       rs3766913       rs3766914       rs3766915       rs3820224       rs4246549       rs4971252       rs4971253       rs5780162       rs6428001       rs6428002       rs6428003       rs6658726       rs6658996       rs6661575       rs6661590       rs6671650       rs6672757       rs6672961       rs6682996       rs6684540       rs6697081       rs6697630       rs7543148       rs10128007      
rs10753939       rs10800912       rs10800913       rs10800914       rs10920615       rs10920616       rs10920617       rs11586935       rs12072017       rs12076420       rs12077300       rs12092451       rs12093676       rs16830263       rs16851349       rs16851364       rs16851388       rs17177486       rs17476264       rs28384397       rs28583560       rs35374993       rs35748853       rs36037256       rs36084653       rs57063050       rs58711618       rs58789157       rs58876285       rs59198840       rs59571468       rs59583954       rs59821503       rs60287688       rs61267456       rs61363542       rs61821277       rs74137620       rs74419933       rs74695496       rs74779206       rs75174511       rs75675978       rs75815232       rs75860259       rs76085480       rs76532691       rs76819192       rs76922959       rs77108653       rs77194840       rs77243796       rs77856193       rs77926499       rs78098463       rs79267632       rs79536246       rs111253573       rs111255010       rs111300721       rs111457702       rs111492732       rs111679604       rs111898627       rs111944373       rs112180969       rs112185002       rs112427219       rs112609349       rs112848354       rs112986235       rs112990462       rs113378403       rs113444349       rs113460347       rs113540063       rs113752933       rs113800166       rs114185541       rs114312865       rs114427727       rs115084802       rs115196187       rs115249326       rs115273750       rs115487737       rs115707922       rs115902891       rs115908597       rs116327143       rs116532903       rs116862163       rs116879447       rs117210368       rs137909169       rs137950007       rs138154984       rs138277496       rs138489292       rs138642838       rs138705652       rs138712293       rs138918636       rs139031901       rs139299015       rs139487477       rs139558095       rs139595480       rs139728195       rs139730140       rs139855707       rs140013273       rs140058345       rs140370642       rs140508278       rs140696046       rs140729800       rs141062511       rs141261757       rs141274927       rs141336017       rs141374551       rs141381973       rs141499373       rs141634546       rs141690882       rs142016007       rs142181369       rs142383714       rs142384055       rs142683129       rs142758428       rs142874129       rs142981560       rs143099671       rs143390804       rs143745268       rs143883652       rs144187736       rs144280314       rs144506167       rs144519375       rs144703371       rs145155618       rs145189135       rs145204405       rs145279616       rs145322178       rs145422243       rs145901742       rs145919497       rs146110343       rs146226389       rs146249859       rs146564523       rs146651749       rs146792441       rs147357402       rs147361294       rs147822966       rs147826492       rs147932290       rs148000218       rs148158641       rs148311417       rs148415837       rs148613876       rs148667187       rs148681759       rs148943869       rs149223620       rs149359233       rs149482844       rs149495524       rs149536264       rs149886220       rs150007990       rs150108365       rs150392896       rs150446898       rs150497071       rs150991415       rs151019521       rs151259181       rs180778082       rs181038989       rs181054150       rs181055483       rs181266813       rs181548819       rs181653657       rs181938022       rs182342550       rs182719469       rs183197075       rs183283575       rs183307011       rs183689215       rs183943815       rs184128785       rs184234679       rs184455107       rs184598037       rs185518440       rs185788983       rs186213787       rs187075337       rs187165853       rs187322794       rs187597004       rs187649901       rs187905211       rs187951072       rs188306969       rs188405927       rs189501779       rs189503633       rs189578886       rs189678593       rs189739500       rs190020382       rs190070481       rs190600742       rs190828021       rs191063924       rs191562847       rs191841937       rs191877049       rs192071928       rs192304543       rs192405730       rs192633587       rs192878925       rs192959862       rs193007327       rs193213987       rs193267995       rs199610583       rs199661779       rs199917381       rs199945576       rs200014281       rs200111599       rs200131296       rs200147359       rs200157198       rs200199509       rs200315118       rs200392600       rs200474119       rs200677188       rs200696594       rs200924838       rs201142494       rs201152036       rs201313469       rs201449311       rs201969614       rs202067923       rs202160348       rs202176996       rs367649884       rs368364663       rs369136071       rs369286937       rs369386758       rs369526958       rs369549642       rs370270022       rs370475053       rs370700379       rs371237431       rs372055897       rs372909728       rs373114828       rs373120646       rs373344896       rs373594801       rs374060031       rs374392393       rs374518065       rs374647360       rs374700313       rs374847025       rs376310218       rs376381456       rs376575413       rs376930920       rs377172235       rs377283001       rs377479219       rs377579436       rs397736099       rs397786852       rs527605302       rs527742118       rs528080465       rs528197958       rs528471781       rs528618873       rs528707535       rs529434044       rs529693924       rs529901197       rs529964228       rs530180627       rs530241332       rs530509017       rs530585006       rs530649565       rs531303834       rs531475249       rs531651719       rs531780210       rs531785745       rs531801284       rs531821658       rs532125089       rs532168636       rs532916505       rs533732798       rs533924890       rs534033513       rs534181950       rs534244255       rs534370866       rs534492615       rs534596779       rs535202641       rs535433589       rs535700282       rs535823132       rs535895574       rs535956856       rs536292079       rs536977170       rs537034679       rs537266188       rs537621102       rs537632568       rs537758246       rs537829972       rs537903543       rs537965570       rs537967902       rs538157842       rs538228466       rs538304008       rs539376539       rs539963775       rs540315108       rs540484510       rs540930170       rs541072232       rs541242346       rs541252433       rs541538843       rs541652416       rs541722567       rs541834338       rs541895766       rs542085259       rs542193902       rs542243510       rs542256565       rs542256898       rs542728037       rs542917686       rs543571369       rs543592864       rs543807251       rs543940491       rs544180803       rs544331466       rs544649368       rs545159622       rs545616207       rs545788555       rs546056800       rs546069321       rs546315765       rs546403011       rs546466318       rs546678651       rs546976129       rs547240258       rs547271929       rs547272179       rs547672037       rs548007098       rs548236044       rs548237596       rs548568669       rs548602984       rs549467635       rs549534498       rs549595919       rs549671286       rs550228561       rs550406876       rs550566086       rs551111786       rs551247229       rs551384312       rs551531012       rs551551740       rs551650633       rs551909483       rs552900171       rs552982540       rs553083983       rs553254537       rs553305285       rs553315889       rs553368321       rs553442279       rs553577813       rs553906886       rs554069965       rs554234537       rs554820872       rs555218176       rs555294159       rs555558909       rs555558950       rs555762330       rs555824712       rs555890433       rs556007632       rs556247243       rs556500304       rs557292381       rs557553803       rs557683506       rs557690221       rs557827047       rs557946872       rs557956798       rs558008434       rs558230108       rs558975725       rs559192908       rs559377510       rs559441563       rs559516215       rs559534138       rs559911268       rs560394184       rs560754638       rs561331687       rs561348237       rs561405280       rs561413013       rs561549204       rs561654703       rs561750048       rs561810876       rs561890589       rs562133596       rs562166372       rs562422190       rs562644954       rs562752187       rs562892602       rs562943126       rs563229140       rs563369791       rs563680200       rs564158292       rs564163741       rs564696812       rs565162609       rs565212741       rs565351593       rs565427839       rs565488214       rs565674927       rs565683446       rs566162902       rs566742341       rs566959536       rs567132546       rs567135132       rs567221629       rs567409508       rs567431683       rs567560312       rs568057738       rs568217201       rs569031980       rs569118604       rs569147686       rs569168258       rs569288242       rs569388712       rs569450770       rs569527061       rs569664810       rs569689950       rs570016807       rs570076252       rs570499013       rs570888934       rs570957944       rs571066777       rs571102029       rs571423190       rs571429797       rs571559603       rs571655240       rs571752324       rs571965938       rs572135709       rs572335539       rs572618627       rs572805618       rs572898010       rs573018416       rs573715091       rs573843866       rs573955320       rs574636598       rs574669786       rs575085197       rs575155267       rs575232998       rs575244887       rs575370269       rs575437360       rs575511941       rs575593023       rs575595256       rs575648925       rs576413155       rs576693645       rs577033061       rs577272275       rs577370652       rs577558232       rs745405873       rs745682104       rs746125671       rs746249888       rs746533057       rs747009358       rs747233041       rs747268376       rs747385609       rs747434529       rs747881241       rs747950849       rs747966893       rs748237704       rs748238121       rs748852635       rs749385572       rs749870909       rs750101833       rs750163069       rs750237487       rs750413007       rs750414592       rs750548233       rs750816904       rs750986449       rs750987880       rs751315701       rs751333729       rs751593122       rs751877296       rs751956477       rs752112437       rs752198789       rs752288531       rs752290430       rs752444177       rs752609674       rs752638614       rs752935066       rs752937396       rs753022474       rs753125407       rs753219251       rs753306989       rs753661433       rs753872532       rs754423384       rs754620580       rs754858881       rs755718510       rs755822195       rs755928134       rs755984199       rs756327835       rs756356819       rs756564558       rs756980560       rs757070471       rs757143665       rs757341985       rs757350202       rs757658881       rs757712941       rs758077408       rs758238654       rs758437090       rs758464605       rs758862040       rs758998234       rs759093515       rs759183381       rs759333337       rs759516364       rs759624889       rs759671087       rs760201545       rs760496564       rs760595111       rs760952445       rs761233065       rs761488097       rs761649531       rs761680300       rs761801836       rs762063968       rs762152396       rs762154455       rs762498280       rs762821018       rs763050638       rs763208184       rs763303009       rs763746687       rs763802825       rs763935937       rs763944124       rs764115774       rs764401923       rs764486572       rs764995093       rs765371047       rs765453522       rs765506639       rs765687714       rs766198188       rs766605045       rs766694592       rs766812573       rs767088977       rs767174888       rs767351118       rs767534708       rs767747763       rs767934884       rs768009921       rs768134221       rs768385270       rs768412407       rs768544358       rs768589807       rs768838898       rs768840329       rs769217928       rs769274620       rs769517548       rs770272900       rs770344633       rs770358969       rs770447264       rs770939371       rs772045623       rs772064053       rs772134963       rs772197154       rs772265764       rs772464229       rs772544245       rs772886348       rs773346947       rs773478079       rs773489520       rs773564439       rs773951782       rs774416390       rs774439814       rs774485644       rs774625135       rs774641258       rs774670463       rs775100009       rs775111384       rs775467919       rs775546532       rs775590878       rs776209600       rs776335168       rs776350105       rs776639176       rs776970434       rs777008306       rs777062182       rs777163434       rs777586224       rs777618689       rs777787246       rs777833449       rs777946743       rs778345234       rs778711602       rs778832543       rs779073728       rs779102960       rs779452688       rs779498869       rs779763875       rs780528401       rs780592241       rs780803961       rs780978710       rs780999394       rs781083284       rs781277783       rs781663545       rs781674354      

基因表达

基因表达

FMOD基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
AACTTGAGAGTTCTCCATCAG
58
CTCAGATCTCGATGAGGCT
58
CAACTTGAGAGTTCTCCATCAG
59
CAGATCTCGATGAGGCTGG
60
CAACTTGAGAGTTCTCCATCAG
59
TCAGATCTCGATGAGGCTG
59
CCTCTCCTACAACCAGCTG
60
TGATGGAGAACTCATTGATCCT
59
CCTCTCCTACAACCAGCTG
60
CTGATGGAGAACTCATTGATCC
59
CAACTTGAGAGTTCTCCATCAG
59
CAGATCTCGATGAGGCTGG
60
AGACCTCTCCTACAACCAG
58
GATGGAGAACTCATTGATCCT
57
CAACTTGAGAGTTCTCCATCAG
59
TCAGATCTCGATGAGGCTG
59
AACTTGAGAGTTCTCCATCAG
58
CTCAGATCTCGATGAGGCT
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

FMOD基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

FMOD基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005576
Q06828(UniProtKB)
TAS
GO:0005576
Q06828(UniProtKB)
TAS
GO:0005576
Q06828(UniProtKB)
TAS
GO:0005578
Q06828(UniProtKB)
IEA
GO:0005615
Q06828(UniProtKB)
IDA
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0005796
Q06828(UniProtKB)
TAS
GO:0007181
Q06828(UniProtKB)
TAS
GO:0007409
Q06828(UniProtKB)
IBA
GO:0008201
Q06828(UniProtKB)
IBA
GO:0018146
Q06828(UniProtKB)
TAS
GO:0030199
Q06828(UniProtKB)
IEA
GO:0042340
Q06828(UniProtKB)
TAS
GO:0043202
Q06828(UniProtKB)
TAS
GO:0043202
Q06828(UniProtKB)
TAS
GO:0035385
Q06828(UniProtKB)
IBA
GO:0048495
Q06828(UniProtKB)
IBA
GO:0048846
Q06828(UniProtKB)
IBA
GO:0050770
Q06828(UniProtKB)
IBA
GO:0031012
Q06828(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控FMOD基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Tendinopathy 0.08 1 0 RGD
Chronic Lymphocytic Leukemia 0.00680591 6 0 BeFree_LHGDN
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 0.00272435 1 0 LHGDN
Hypertensive disease 0.002367032 1 0 GAD
Myopia 0.002367032 1 0 GAD
Severe myopia 0.000814326 3 0 BeFree
Arteriosclerosis 0.000271442 1 0 BeFree
Atherosclerosis 0.000271442 1 0 BeFree
Kidney Diseases 0.000271442 1 0 BeFree
Liver Cirrhosis 0.000271442 1 0 BeFree
Urinary Stress Incontinence 0.000271442 1 0 BeFree
Fibrosis, Liver 0.000271442 1 0 BeFree
Age related macular degeneration 0.000271442 1 0 BeFree
Cirrhosis 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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