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Three distinct, but closely related classes of receptors that bind the Fc portion of IgG have been identified (Fcgamma RI, II and III). The FcgammaRI family consists of three closely related genes termed A, B, and C. This gene encodes the low affinity FcgammaRIB receptor that may play an important role in humoral immune response. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
[中文简述(自动翻译):]  三个不同,但密切相关的类结合IgG的Fc部分已经确定受体(Fcgamma RI,II和III)。的FcgammaRI家族由三个密切相关的基因,称为A,B和C该基因编码的低亲和力FcgammaRIB受体可在体液免疫应答中发挥重要作用。编码不同同种型的可变剪接转录物变体已被用于这个基因说明。 [由RefSeq的,2011年10月提供]
FCGR1B基因(以及对应的蛋白质)的细胞分布位置:
FCGR1B基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Alopecia Areata | 0.00272435 | 1 | 0 | LHGDN |
Malignant neoplasm of breast | 0.002638474 | 2 | 1 | BeFree_GAD |
Asthma | 0.002367032 | 1 | 0 | GAD |
Breast Carcinoma | 0.000271442 | 1 | 1 | BeFree |
Mammary Neoplasms | 0.000271442 | 1 | 1 | BeFree |
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