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This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternative splicing of this gene generates at least 3 transcript variants diverging at the 5' terminus. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  该基因编码在F-box蛋白家族,其特征是一个约40个氨基酸基序,在F-盒的成员。在F-box蛋白组成四个亚基被叫泛素蛋白连接酶复合SCFS(SKP1-滞-F-箱)中的其中一个功能的磷酸化依赖泛素化。在F-box蛋白被分为3类:Fbws含WD-40结构域,含有Fbls富含亮氨酸的重复序列,以及含有任一不同的蛋白质 - 蛋白质相互作用的模块或没有可识别的图案Fbxs。由该基因编码的蛋白质属于Fbxs类。这个基因的可变剪接产生至少3转录变体在5‘末端发散。 [由RefSeq的,2008年7月提供]
FBXO9基因(以及对应的蛋白质)的细胞分布位置:
FBXO9基因的本体(GO)信息:
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