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This gene is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to function as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  此基因是由五个编码小的分泌蛋白质高度同源的基因的TAFA家族的一个成员。这些蛋白质包含在固定位置保守的半胱氨酸残基,并且远亲MIP-1α,则CC趋化因子家族的一个成员。的TAFA蛋白质在大脑的特定区域主要表达,并且被假定作为脑特异性趋化因子或neurokines,充当免疫和神经细胞的调节剂。 [由RefSeq的,2008年7月提供]
FAM19A2基因(以及对应的蛋白质)的细胞分布位置:
FAM19A2基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Chronic Obstructive Airway Disease | 0.12 | 1 | 1 | GWASCAT |
Obesity | 0.12 | 1 | 1 | GWASCAT |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Mental impairment | 0.000271442 | 1 | 0 | BeFree |
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