更多...
收起
This gene encodes a single-pass membrane protein which functions as a glycosyltransferase. The encoded protein catalyzes the transfer of N-acetylglucosamine to glycosaminoglycan chains. This reaction is important in heparin and heparan sulfate synthesis. Alternative splicing results in the multiple transcript variants. [provided by RefSeq, Nov 2012]
[中文简述(自动翻译):]  这个基因编码一单通膜蛋白,其功能是作为糖基转移酶。所编码的蛋白质催化N-乙酰葡糖胺转移到糖胺聚糖链。此反应是在肝素和硫酸乙酰肝素合成重要。选择性剪接的结果在多个转录变体。 [通过的RefSeq,2012十一月提供]
EXTL3基因(以及对应的蛋白质)的细胞分布位置:
EXTL3基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Colorectal Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
| Cessation of life | 0.00272435 | 1 | 0 | LHGDN |
| Malignant neoplasm of breast | 0.000814326 | 3 | 0 | BeFree |
| Breast Carcinoma | 0.000814326 | 3 | 0 | BeFree |
| Carcinoma of lung | 0.000814326 | 3 | 0 | BeFree |
| Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Glioblastoma | 0.000542884 | 2 | 0 | BeFree |
| Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
| Coronary Arteriosclerosis | 0.000271442 | 1 | 0 | BeFree |
| Coronary heart disease | 0.000271442 | 1 | 0 | BeFree |
| External exotoses | 0.000271442 | 1 | 0 | BeFree |
| Hereditary Multiple Exostoses | 0.000271442 | 1 | 0 | BeFree |
| Mucopolysaccharidoses | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Carcinoma, Lewis Lung | 0.000271442 | 1 | 0 | BeFree |
| Cancer of Head and Neck | 0.000271442 | 1 | 0 | BeFree |
| Endothelial dysfunction | 0.000271442 | 1 | 0 | BeFree |
| Coronary Artery Disease | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。