EPPIN(epididymal peptidase inhibitor)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

20q13.12
基因染色体位置图

基因简述

基因简述

This gene encodes an epididymal protease inhibitor, which contains both kunitz-type and WAP-type four-disulfide core (WFDC) protease inhibitor consensus sequences. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene is a member of the WFDC gene family and belongs to the telomeric cluster. The protein can inhibit human sperm motility and exhibits antimicrobial activity against E. coli, and polymorphisms in this gene are associated with male infertility. Read-through transcription also exists between this gene and the downstream WFDC6 (WAP four-disulfide core domain 6) gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

[中文简述(自动翻译):]  这个基因编码的附睾蛋白酶抑制剂，它包含Kunitz型和WAP型四二硫化物核心（WFDC）蛋白酶抑制剂的共有序列。大多数WFDC基因定位于染色体20q12-Q13在两个集群：着丝粒和端粒。此基因是WFDC基因家族的成员，属于端粒群集。该蛋白质能抑制人精子运动并显示出抗大肠杆菌的抗菌活性，并且在该基因多态性与男性不育相关联。通读转录还此基因和下游WFDC6（WAP四二硫化物核心域6）基因之间存在。已发现该基因编码不同亚型的两个转录变异体。 [由RefSeq的，2014年11月提供]

OMIM数据库中对EPPIN基因的介绍     Wikipedia数据库中对EPPIN基因的介绍

基因序列

基因序列

EPPIN基因的碱基序列：[NCBI]

基因突变

基因突变

EPPIN基因的碱基突变：           显示全部snp
rs11594       rs765156       rs2064273       rs2064274       rs2227290       rs2231829       rs2231830       rs2231831       rs2231832       rs2231833       rs2231834       rs2231835       rs2231836       rs2231837       rs2231838       rs2231839       rs2231840       rs2231841       rs2231842       rs2231843       rs2231844       rs2235584       rs2868303       rs4278989       rs6017602       rs6017603       rs6017604       rs6017605       rs6017606       rs6017607       rs6017608       rs6032280       rs6032281       rs6032285       rs6032287       rs6032288       rs6032289      
rs6032291       rs6032292       rs6032293       rs6032294       rs6094162       rs6094163       rs6094164       rs6094165       rs6104200       rs6104201       rs6104202       rs6104203       rs6104204       rs6104205       rs6104206       rs6104207       rs6104208       rs6104209       rs6104211       rs6124713       rs6124715       rs7361329       rs11473268       rs11481728       rs12480626       rs45446094       rs45452198       rs45470793       rs57015374       rs57154593       rs57263161       rs59190933       rs59279561       rs60996959       rs73288221       rs73910209       rs73910221       rs73910225       rs73910226       rs74486585       rs75487503       rs75653982       rs75681320       rs76043630       rs76305031       rs77206428       rs77847898       rs78370344       rs78680601       rs78834875       rs78898485       rs79324074       rs111530139       rs111544339       rs112337092       rs112693327       rs112699354       rs112713275       rs112762127       rs113007031       rs113029215       rs113413521       rs113693341       rs114346403       rs114712465       rs115336187       rs115479208       rs117231492       rs137891979       rs138058709       rs138351567       rs138674988       rs139297104       rs139564349       rs139633666       rs139660452       rs139673568       rs140030357       rs140203194       rs140667143       rs141111300       rs141315389       rs142674986       rs142763330       rs143398187       rs143540594       rs143681828       rs143785210       rs143891238       rs144075251       rs145043352       rs145047130       rs145186344       rs145305060       rs146039239       rs146262917       rs146783830       rs146805112       rs146941859       rs147369513       rs147379045       rs148135555       rs148657280       rs148929549       rs149481727       rs149637606       rs150003146       rs150263053       rs150486053       rs180758228       rs180915889       rs181741444       rs181807045       rs181879305       rs182310363       rs182669278       rs182779034       rs182887407       rs183542384       rs183664369       rs184082842       rs184341971       rs184882621       rs185156322       rs186492701       rs186637249       rs186780190       rs187227481       rs187328275       rs188051876       rs188330376       rs188765946       rs188835906       rs188961971       rs189767346       rs189987309       rs190154691       rs190586225       rs191285714       rs191396319       rs191626223       rs191697174       rs192431176       rs192455585       rs192862954       rs192976045       rs193086651       rs199533646       rs199878924       rs199909423       rs200282357       rs200975605       rs202204072       rs368578112       rs368584765       rs369195525       rs369542899       rs370174917       rs370473242       rs371675521       rs371776087       rs373013553       rs373594557       rs373850475       rs374185808       rs374476441       rs374792773       rs374858005       rs375029512       rs376765772       rs376857550       rs377370959       rs377706528       rs527669087       rs528266679       rs528873733       rs529481247       rs529492406       rs531232823       rs531776435       rs532420155       rs532459635       rs532896340       rs533208295       rs533215012       rs533525430       rs533675228       rs534042725       rs534439957       rs535014254       rs535135884       rs535322106       rs535473089       rs535682884       rs535764356       rs536165212       rs536976026       rs538044406       rs538074319       rs538459839       rs539072209       rs539372625       rs540134803       rs540259288       rs541101302       rs542246761       rs543491628       rs544298055       rs544460673       rs544592695       rs545198569       rs545531701       rs545534491       rs545832263       rs546102307       rs547126952       rs547635430       rs548053770       rs548378208       rs548562423       rs548650236       rs549828537       rs549931402       rs551127177       rs552166727       rs552367257       rs552579936       rs553093097       rs553421164       rs553687137       rs554023083       rs555085590       rs555117490       rs556365582       rs556383784       rs556422609       rs556422754       rs556507626       rs557533370       rs557661451       rs558026539       rs558361328       rs558714067       rs558975866       rs559912550       rs560175710       rs560213040       rs560216407       rs560424218       rs560550446       rs560563732       rs560638322       rs561566898       rs561755783       rs561844031       rs562075443       rs562331860       rs562529954       rs562681520       rs562766476       rs562953821       rs563141468       rs564235886       rs564255153       rs565600382       rs566286094       rs566405912       rs566442732       rs566923955       rs566994753       rs567488094       rs568340768       rs568375272       rs569210858       rs569296736       rs569537093       rs570396454       rs570448304       rs570730459       rs570768683       rs570851814       rs570956628       rs571476040       rs572186617       rs572203549       rs572386062       rs572819266       rs573415611       rs573450682       rs573675706       rs573763671       rs574678140       rs574754366       rs574956833       rs575894665       rs576823460       rs577060906       rs577097902       rs578070185       rs745838186       rs746119354       rs746265586       rs746956323       rs747118674       rs747743218       rs747875278       rs748888888       rs749696714       rs750263483       rs750482019       rs751229092       rs751377077       rs751892351       rs751896217       rs752038013       rs752127310       rs752179668       rs752875629       rs753017282       rs753086028       rs753368998       rs753843555       rs753995824       rs754889576       rs755220549       rs755310294       rs755570633       rs756122913       rs756228608       rs756510151       rs756936989       rs757011496       rs757772604       rs758090000       rs759407126       rs759530211       rs760304044       rs760373674       rs760395694       rs760474176       rs761392117       rs761896300       rs762018967       rs762072398       rs762368469       rs763532286       rs763637870       rs764259127       rs764287317       rs764596402       rs764722304       rs764988226       rs764993651       rs765342353       rs765580262       rs765586795       rs766440090       rs766823753       rs766974861       rs767156713       rs767409491       rs767738115       rs767810300       rs768112471       rs768402242       rs768444278       rs768790667       rs769413341       rs769719273       rs770024030       rs770311343       rs771216018       rs771338913       rs771546199       rs771928109       rs772318702       rs774389367       rs774775135       rs775112653       rs775133667       rs775460084       rs775808265       rs776110456       rs776136593       rs776361026       rs776380931       rs776896589       rs777291711       rs777697579       rs777717270       rs778345231       rs778558072       rs778768147       rs779348076       rs779401161       rs779612419       rs780362044       rs780430316       rs780515330       rs781059536       rs781468902       rs781677565      

基因表达

基因表达

EPPIN基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CATGTTTGTCTATGGTGGCTG
60
AGGGAAAGCGTTTATTCTTGC
60
GATCTCAAACAAGATGTATGCG
58
ACCATAGACAAACATGGAGC
58
CCATGTTTGTCTATGGTGGC
59
AGGGAAAGCGTTTATTCTTGC
60
GATCTCAAACAAGATGTATGCG
58
CCACCATAGACAAACATGGA
58
TGATTGGTTATTTCCCAGGAG
58
CATTGTCTGTCCTTTGTACAC
57
GATCTCAAACAAGATGTATGCG
58
CCATAGACAAACATGGAGCA
58
GGTTATTTCCCAGGAGATGTC
58
CATTGTCTGTCCTTTGTACAC
57
GATCTCAAACAAGATGTATGCG
58
CCACCATAGACAAACATGGA
58
GATCTCAAACAAGATGTATGCG
58
CCATAGACAAACATGGAGCA
58
GGTTATTTCCCAGGAGATGTC
58
CATTGTCTGTCCTTTGTACAC
57

转录因子

转录因子

      尚未收录相关数据

基因本体信息

EPPIN基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

EPPIN基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005576
B7ZBA9(UniProtKB)
IEA
GO:0010466
B7ZBA9(UniProtKB)
IEA
GO:0030414
B7ZBA9(UniProtKB)
IEA
GO:0004867
O95925(UniProtKB)
IEA
GO:0005515
O95925(UniProtKB)
IPI
GO:0005515
O95925(UniProtKB)
IPI
GO:0005515
O95925(UniProtKB)
IPI
GO:0005515
O95925(UniProtKB)
IPI
GO:0005615
O95925(UniProtKB)
IDA
GO:0009986
O95925(UniProtKB)
IDA
GO:0010466
O95925(UniProtKB)
IDA
GO:0010951
O95925(UniProtKB)
IEA
GO:0042742
O95925(UniProtKB)
IDA
GO:0043234
O95925(UniProtKB)
IDA
GO:0051259
O95925(UniProtKB)
IDA
GO:0090281
O95925(UniProtKB)
IMP
GO:1901318
O95925(UniProtKB)
IMP

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控EPPIN基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Male infertility 0.005005506 2 0 BeFree_GAD

基因相关文献

基因相关文献

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基因相关服务

基因相关服务

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