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This gene encodes a member of the apyrase protein family. Apyrases are enzymes that catalyze the hydrolysis of nucleotide diphosphates and triphosphates in a calcium or magnesium-dependent manner. The encoded protein is an endo-apyrase and may play a role in salvaging nucleotides from lysosomes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and these isoforms may differ in divalent cation dependence and substrate specificity. [provided by RefSeq, Sep 2011]
[中文简述(自动翻译):]  该基因编码的apyrase蛋白家族的一个成员。 Apyrases是催化核苷酸二磷酸和三磷酸水解以钙或镁依赖性酶。所编码的蛋白质是一个内切apyrase并在从溶酶体打捞核苷酸可以发挥作用。可变剪接转录物变体编码的多个同种型已被用于这个基因观察到,并且这些异构体可以在二价阳离子依赖性和底物特异性不同。 [由RefSeq的,2011年9月提供]
ENTPD4基因(以及对应的蛋白质)的细胞分布位置:
ENTPD4基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Schizophrenia | 0.002638474 | 1 | 0 | BeFree_GAD |
| Alcoholic Intoxication, Chronic | 0.002367032 | 1 | 0 | GAD |
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