ENSA(endosulfine alpha) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

1q21.3
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene belongs to a highly conserved cAMP-regulated phosphoprotein (ARPP) family. This protein was identified as an endogenous ligand for the sulfonylurea receptor, ABCC8/SUR1. ABCC8 is the regulatory subunit of the ATP-sensitive potassium (KATP) channel, which is located on the plasma membrane of pancreatic beta cells and plays a key role in the control of insulin release from pancreatic beta cells. This protein is thought to be an endogenous regulator of KATP channels. In vitro studies have demonstrated that this protein modulates insulin secretion through the interaction with KATP channel, and this gene has been proposed as a candidate gene for type 2 diabetes. At least eight alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于高度保守的cAMP调节的磷蛋白（ARPP）的家庭。该蛋白质被鉴定为内源性配体的磺酰脲受体，ABCC8 / SUR1。 ABCC8是ATP敏感性钾离子（KATP）信道，它位于胰腺β细胞的质膜的调节亚基和在胰岛素释放从胰腺β细胞的控制的关键作用。这种蛋白质被认为是KATP通道的内源性调节剂。体外研究已经证实，该蛋白通过与KATP通道的相互作用调节胰岛素的分泌，而这基因已经被提出作为候选基因的2型糖尿病。至少八个可变剪接转录物变体编码不同同种型已被观察到。 [由RefSeq的，2008年7月提供]

OMIM数据库中对ENSA基因的介绍     Wikipedia数据库中对ENSA基因的介绍

基因序列

基因序列

ENSA基因的碱基序列：[NCBI]

基因突变

基因突变

ENSA基因的碱基突变：           显示全部snp
rs882       rs884       rs886       rs7517       rs1053701       rs1053731       rs1053732       rs1058183       rs1962138       rs1971378       rs2055974       rs2280078       rs2867310       rs4970967       rs6682136       rs11204682       rs11550418       rs11579860       rs11581902       rs12023300       rs12032259       rs12061745       rs12743165       rs17847053       rs17847054       rs17847055       rs35048125       rs35118879       rs41266899       rs41266901       rs41266903       rs57705271       rs71580318       rs74124942       rs74124944       rs74348525       rs75075738      
rs75669298       rs75791350       rs76951202       rs77115129       rs78646592       rs78880417       rs79906755       rs79956336       rs80212492       rs111543978       rs111962711       rs112139865       rs112205357       rs112407752       rs112523257       rs112688380       rs113445589       rs113646349       rs113682116       rs113697732       rs113860862       rs115203304       rs115406107       rs115879718       rs116176998       rs116221964       rs116437946       rs117968841       rs118186764       rs138139567       rs138144477       rs138271290       rs138848644       rs138939023       rs140316301       rs140520803       rs140626441       rs141017549       rs141259566       rs141339813       rs141944696       rs142238932       rs142896422       rs143595921       rs144160322       rs144592658       rs145047562       rs145066710       rs145166763       rs145743127       rs145869882       rs146911121       rs147159932       rs147572956       rs148754482       rs149019663       rs149334531       rs150444624       rs150572364       rs150783729       rs151099744       rs151318123       rs181014128       rs181236187       rs181520646       rs181943088       rs182440078       rs183044697       rs183295064       rs183764261       rs183852691       rs184222578       rs184709906       rs184777356       rs184943355       rs185945600       rs186494882       rs186736317       rs186747174       rs186901807       rs187603477       rs188406929       rs189073616       rs189503757       rs189946993       rs190942315       rs190979109       rs191097653       rs191186947       rs191252530       rs191587632       rs192484433       rs192781884       rs199701865       rs199971299       rs200689397       rs200916561       rs201267816       rs201770029       rs201883426       rs367689257       rs367854238       rs368889778       rs369337537       rs369618778       rs369716092       rs369922289       rs370041094       rs370227773       rs370302073       rs370452601       rs371012312       rs372022946       rs372478434       rs372649778       rs372855492       rs372867833       rs373509426       rs373845676       rs374404692       rs374974585       rs375460829       rs375702583       rs376153418       rs376642323       rs376923966       rs377107762       rs377703420       rs377759785       rs587594676       rs587594909       rs587595685       rs587597416       rs587597954       rs587601263       rs587602856       rs587603457       rs587604903       rs587605016       rs587605662       rs587606221       rs587609067       rs587610444       rs587610668       rs587611627       rs587612251       rs587613552       rs587616642       rs587618879       rs587619112       rs587619591       rs587620271       rs587620299       rs587628378       rs587628485       rs587630064       rs587630875       rs587630968       rs587633139       rs587634147       rs587634411       rs587635010       rs587637921       rs587638267       rs587638398       rs587642584       rs587643884       rs587646347       rs587646921       rs587647594       rs587648133       rs587648697       rs587650788       rs587653351       rs587655461       rs587659003       rs587659878       rs587660137       rs587661869       rs587662361       rs587663074       rs587665353       rs587666687       rs587666833       rs587668355       rs587669662       rs587670673       rs587671513       rs587671618       rs587672876       rs587673036       rs587673684       rs587673973       rs587676276       rs587676325       rs587676980       rs587681347       rs587685079       rs587685553       rs587687665       rs587690748       rs587690910       rs587695752       rs587696237       rs587696248       rs587699905       rs587699921       rs587702062       rs587705660       rs587705814       rs587706056       rs587706257       rs587706412       rs587707017       rs587710033       rs587710181       rs587711000       rs587711961       rs587714097       rs587715685       rs587716873       rs587718282       rs587721559       rs587723103       rs587723436       rs587723497       rs587729435       rs587729545       rs587730927       rs587733172       rs587736036       rs587736327       rs587738131       rs587738658       rs587738791       rs587741475       rs587741996       rs587742468       rs587744963       rs587746858       rs587751580       rs587751720       rs587752249       rs587753935       rs587754457       rs587756891       rs587757890       rs587758800       rs587759689       rs587760972       rs587763053       rs587765238       rs587765362       rs587766377       rs587767063       rs587770057       rs587770168       rs587771129       rs587772367       rs587772584       rs587773304       rs745403609       rs745693911       rs745831590       rs746249586       rs746320151       rs746938934       rs747221558       rs747403259       rs747964785       rs748021169       rs748318830       rs749162884       rs749688538       rs749862359       rs750303030       rs750443063       rs750468165       rs750798198       rs750966911       rs750985863       rs751325976       rs751469856       rs752026890       rs752130840       rs752239839       rs752327518       rs752396164       rs753076730       rs753096741       rs753552630       rs753837481       rs754043338       rs754074553       rs754543263       rs754766537       rs754829427       rs755306258       rs755659410       rs755805529       rs756389368       rs756396397       rs756514812       rs757171377       rs757226308       rs757289095       rs757658447       rs757987232       rs758099926       rs758219128       rs758430613       rs758637615       rs758879314       rs759307017       rs759538315       rs759597636       rs759685925       rs760238315       rs760423212       rs760569083       rs761016976       rs761126935       rs761326360       rs761756205       rs762080928       rs762364316       rs762396214       rs762517717       rs763394268       rs763517061       rs763650351       rs763703590       rs763878282       rs764253231       rs764662431       rs764693193       rs764787362       rs765281094       rs765525047       rs765707789       rs766248651       rs766375677       rs766507233       rs766591643       rs766844905       rs767225802       rs767351675       rs767823281       rs768102856       rs768393663       rs768563248       rs768605869       rs768741308       rs768919993       rs768956843       rs769408580       rs769517075       rs769640441       rs769751729       rs770411929       rs770662033       rs770715460       rs771113917       rs771318784       rs771660957       rs771699112       rs772214484       rs772314823       rs772364871       rs772494336       rs772576991       rs773370931       rs773423871       rs773531510       rs773811012       rs773865958       rs773901826       rs774126662       rs774156801       rs774172805       rs774394701       rs774567483       rs775332541       rs775530234       rs775536016       rs776271735       rs776464335       rs776664904       rs776840279       rs777078545       rs777283764       rs777299672       rs777425265       rs778667498       rs778844671       rs779021515       rs779309902       rs779698023       rs779711387       rs779749276       rs780385109       rs780434035       rs780558465       rs780577412       rs780752300       rs781200378       rs781464885       rs781583204       rs869284024      

基因表达

基因表达

ENSA基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TTGAACAGAAGTAGAGGCG
57
CATGTTGTAGTCTCCTGAGTC
58
TTCGAATGAAGTCTGTAGAGC
58
GCTTTGGCCATGTTGTAGTC
60
CTTCGAATGAAGTCTGTAGAGC
59
CTTTGGCCATGTTGTAGTCTC
59
CAAATACCCAAGCCTAGGAC
58
TTGCCCTTTCTGGAGTCTC
59
AAGAGACTCCAGAAAGGGC
59
TCTTCATCTTGGCTTTGGC
59
TGAACAGAAGTAGAGGCGA
58
CATGTTGTAGTCTCCTGAGTC
58
CCCTTACACTCCACAGTCC
59
CTTCTTTCTCCTGCGTGTC
59
GAGCAACCCTAGTGACAGG
60
GAGCGAGGACTTTCTCTGG
60
CTCTGTGCGGATGAAATGC
60
CTTCATCTTGGCTTTGGCC
60
ATGAAGAGACTCCAGAAAGGG
59
GCATTTCATCCGCACAGAG
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

ENSA基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ENSA基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000086
O43768(UniProtKB)
ISS
GO:0004864
O43768(UniProtKB)
IEA
GO:0005102
O43768(UniProtKB)
IDA
GO:0005515
O43768(UniProtKB)
IPI
GO:0005654
O43768(UniProtKB)
TAS
GO:0005737
O43768(UniProtKB)
IEA
GO:0006810
O43768(UniProtKB)
TAS
GO:0007067
O43768(UniProtKB)
ISS
GO:0007584
O43768(UniProtKB)
TAS
GO:0008200
O43768(UniProtKB)
TAS
GO:0008601
O43768(UniProtKB)
ISS
GO:0009749
O43768(UniProtKB)
IEA
GO:0019212
O43768(UniProtKB)
ISS
GO:0019870
O43768(UniProtKB)
IDA
GO:0034047
O43768(UniProtKB)
IEA
GO:0043086
O43768(UniProtKB)
IEA
GO:0043086
O43768(UniProtKB)
IEA
GO:0050796
O43768(UniProtKB)
IDA
GO:0051301
O43768(UniProtKB)
IEA
GO:0051721
O43768(UniProtKB)
ISS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控ENSA基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Myocardial Ischemia 0.12 1 0 CTD_human
Down Syndrome 0.00272435 1 0 LHGDN
Diabetes Mellitus, Non-Insulin-Dependent 0.000814326 3 0 BeFree

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基因相关服务

基因相关服务

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