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This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 2) is expressed in brain, heart and skeletal muscle, and the other isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas. This gene may be critical in the development of ovarian cancer. [provided by RefSeq, Mar 2014]
[中文简述(自动翻译):]  该基因编码延伸因子-1复合物,它是负责酶输送氨的tRNA向核糖体的α亚基的同种型。这种同种型(α - 2)在脑,心脏和骨骼肌,以及其它同种型(阿尔法1)表示在脑,胎盘,肺,肝,肾和胰腺中表达。这个基因可以是在卵巢癌的发展是至关重要的。 [由RefSeq的,2014年3月提供]
EEF1A2基因(以及对应的蛋白质)的细胞分布位置:
EEF1A2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Stomach Neoplasms | 0.12 | 1 | 0 | CTD_human |
| Nerve Degeneration | 0.08 | 1 | 0 | RGD |
| Myopathy | 0.017100838 | 63 | 1 | BeFree |
| Hypercholesterolemia, Familial | 0.012757768 | 47 | 2 | BeFree |
| Coronary heart disease | 0.009771907 | 36 | 4 | BeFree |
| Coronary Arteriosclerosis | 0.006514605 | 24 | 2 | BeFree |
| Cardiovascular Diseases | 0.005971721 | 22 | 0 | BeFree |
| Coronary Artery Disease | 0.005971721 | 22 | 1 | BeFree |
| Hypercholesterolemia | 0.004071628 | 15 | 0 | BeFree |
| Diabetes | 0.003800186 | 14 | 0 | BeFree |
| Diabetes Mellitus | 0.003800186 | 14 | 0 | BeFree |
| ovarian neoplasm | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Mammary Neoplasms | 0.003267234 | 2 | 0 | BeFree_LHGDN |
| Adenocarcinoma | 0.00272435 | 1 | 0 | LHGDN |
| Liver carcinoma | 0.00272435 | 1 | 0 | LHGDN |
| Malignant neoplasm of breast | 0.002442977 | 9 | 0 | BeFree |
| Diabetes Mellitus, Non-Insulin-Dependent | 0.002442977 | 9 | 1 | BeFree |
| Myocardial Infarction | 0.002442977 | 9 | 0 | BeFree |
| Myalgia | 0.002442977 | 9 | 0 | BeFree |
| Dyslipidemias | 0.002442977 | 9 | 1 | BeFree |
| Breast Carcinoma | 0.002442977 | 9 | 0 | BeFree |
| Arteriosclerosis | 0.002171535 | 8 | 1 | BeFree |
| Ovarian Carcinoma | 0.002171535 | 8 | 0 | BeFree |
| Malignant neoplasm of ovary | 0.002171535 | 8 | 0 | BeFree |
| Atherosclerosis | 0.001900093 | 7 | 1 | BeFree |
| Neoplasm Metastasis | 0.001628651 | 6 | 0 | BeFree |
| Malignant neoplasm of prostate | 0.001628651 | 6 | 0 | BeFree |
| Colorectal Carcinoma | 0.001357209 | 5 | 1 | BeFree |
| Vascular Diseases | 0.001357209 | 5 | 0 | BeFree |
| Prostate carcinoma | 0.001357209 | 5 | 0 | BeFree |
| Colorectal Cancer | 0.001357209 | 5 | 1 | BeFree |
| Presenile dementia | 0.001085767 | 4 | 0 | BeFree |
| Hyperlipidemia | 0.001085767 | 4 | 0 | BeFree |
| Obesity | 0.001085767 | 4 | 0 | BeFree |
| Dementia | 0.001085767 | 4 | 0 | BeFree |
| Alzheimer's Disease | 0.000814326 | 3 | 0 | BeFree |
| Ischemia | 0.000814326 | 3 | 0 | BeFree |
| leukemia | 0.000814326 | 3 | 0 | BeFree |
| Cerebrovascular accident | 0.000814326 | 3 | 0 | BeFree |
| Wasting | 0.000814326 | 3 | 0 | BeFree |
| Parkinsonian Disorders | 0.000814326 | 3 | 1 | BeFree |
| Muscle damage | 0.000814326 | 3 | 0 | BeFree |
| Carcinogenesis | 0.000814326 | 3 | 0 | BeFree |
| Aortic Aneurysm | 0.000542884 | 2 | 0 | BeFree |
| Rheumatoid Arthritis | 0.000542884 | 2 | 0 | BeFree |
| Asthma | 0.000542884 | 2 | 0 | BeFree |
| Cystic Fibrosis | 0.000542884 | 2 | 0 | BeFree |
| Epilepsy | 0.000542884 | 2 | 0 | BeFree |
| Hyperlipidemia, Familial Combined | 0.000542884 | 2 | 0 | BeFree |
| Osteosarcoma | 0.000542884 | 2 | 0 | BeFree |
| Schizophrenia | 0.000542884 | 2 | 0 | BeFree |
| Myocardial Ischemia | 0.000542884 | 2 | 0 | BeFree |
| Tumor Progression | 0.000542884 | 2 | 0 | BeFree |
| Pancreatic carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000542884 | 2 | 0 | BeFree |
| Drug usage | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of pancreas | 0.000542884 | 2 | 0 | BeFree |
| Hepatitis C, Chronic | 0.000542884 | 2 | 0 | BeFree |
| Osteosarcoma of bone | 0.000542884 | 2 | 0 | BeFree |
| Carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
| Acute Coronary Syndrome | 0.000542884 | 2 | 0 | BeFree |
| Cardiovascular morbidity | 0.000542884 | 2 | 0 | BeFree |
| Chronic Kidney Diseases | 0.000542884 | 2 | 0 | BeFree |
| Adenoma | 0.000271442 | 1 | 0 | BeFree |
| Anemia, Sickle Cell | 0.000271442 | 1 | 0 | BeFree |
| Angina, Unstable | 0.000271442 | 1 | 0 | BeFree |
| Tooth Attrition | 0.000271442 | 1 | 0 | BeFree |
| Malignant tumor of colon | 0.000271442 | 1 | 0 | BeFree |
| Rectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Carotid Artery Diseases | 0.000271442 | 1 | 0 | BeFree |
| Diabetic Angiopathies | 0.000271442 | 1 | 0 | BeFree |
| Disseminated Intravascular Coagulation | 0.000271442 | 1 | 0 | BeFree |
| Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
| Graft-vs-Host Disease | 0.000271442 | 1 | 0 | BeFree |
| Hepatitis C | 0.000271442 | 1 | 0 | BeFree |
| Hodgkin Disease | 0.000271442 | 1 | 0 | BeFree |
| Huntington Disease | 0.000271442 | 1 | 0 | BeFree |
| Chronic Lymphocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Acute Promyelocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Chronic Obstructive Airway Disease | 0.000271442 | 1 | 0 | BeFree |
| Lupus Erythematosus, Systemic | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of stomach | 0.000271442 | 1 | 0 | BeFree |
| melanoma | 0.000271442 | 1 | 0 | BeFree |
| Multiple Myeloma | 0.000271442 | 1 | 0 | BeFree |
| Multiple Sclerosis | 0.000271442 | 1 | 0 | BeFree |
| Muscle Cramp | 0.000271442 | 1 | 0 | BeFree |
| Myotonic Dystrophy | 0.000271442 | 1 | 0 | BeFree |
| nervous system disorder | 0.000271442 | 1 | 0 | BeFree |
| Neuritis | 0.000271442 | 1 | 0 | BeFree |
| Osteoporosis | 0.000271442 | 1 | 1 | BeFree |
| Plasmacytoma | 0.000271442 | 1 | 0 | BeFree |
| Pseudoxanthoma Elasticum | 0.000271442 | 1 | 0 | BeFree |
| Psoriasis | 0.000271442 | 1 | 0 | BeFree |
| Torsades de Pointes | 0.000271442 | 1 | 0 | BeFree |
| Virus Diseases | 0.000271442 | 1 | 0 | BeFree |
| Werner Syndrome | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
| Acute myocardial infarction | 0.000271442 | 1 | 0 | BeFree |
| Porphyria Cutanea Tarda | 0.000271442 | 1 | 0 | BeFree |
| Diabetic Foot | 0.000271442 | 1 | 0 | BeFree |
| Age related macular degeneration | 0.000271442 | 1 | 0 | BeFree |
| Coronary artery atheroma | 0.000271442 | 1 | 0 | BeFree |
| Solid tumour | 0.000271442 | 1 | 0 | BeFree |
| Obesity, Abdominal | 0.000271442 | 1 | 0 | BeFree |
| Restenosis | 0.000271442 | 1 | 0 | BeFree |
| Senile Plaques | 0.000271442 | 1 | 0 | BeFree |
| Impaired cognition | 0.000271442 | 1 | 0 | BeFree |
| Malignant mesothelioma | 0.000271442 | 1 | 0 | BeFree |
| Congenital Myotonic Dystrophy | 0.000271442 | 1 | 0 | BeFree |
| Metabolic Syndrome X | 0.000271442 | 1 | 0 | BeFree |
| Chronic idiopathic urticaria | 0.000271442 | 1 | 0 | BeFree |
| Colon Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Stomach Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Idiopathic Inflammatory Myopathies | 0.000271442 | 1 | 0 | BeFree |
| Endothelial dysfunction | 0.000271442 | 1 | 0 | BeFree |
| cancer recurrence | 0.000271442 | 1 | 0 | BeFree |
| Ischemic stroke | 0.000271442 | 1 | 0 | BeFree |
| Mild cognitive disorder | 0.000271442 | 1 | 0 | BeFree |
| Postoperative confusion | 0.000271442 | 1 | 0 | BeFree |
| Pancreatic Ductal Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Peripheral Arterial Diseases | 0.000271442 | 1 | 0 | BeFree |
| Mixed hyperlipidemia (disorder) | 0.000271442 | 1 | 0 | BeFree |
| Early-Stage Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Ischemic Cerebrovascular Accident | 0.000271442 | 1 | 0 | BeFree |
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