EEF1A1(eukaryotic translation elongation factor 1 alpha 1)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

6q14.1
基因染色体位置图

基因简述

基因简述

This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha 1) is expressed in brain, placenta, lung, liver, kidney, and pancreas, and the other isoform (alpha 2) is expressed in brain, heart and skeletal muscle. This isoform is identified as an autoantigen in 66% of patients with Felty syndrome. This gene has been found to have multiple copies on many chromosomes, some of which, if not all, represent different pseudogenes. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码延伸因子-1复合物，它是负责酶输送氨的tRNA向核糖体的α亚基的同种型。这种同种型（阿尔法1）在脑，胎盘，肺，肝，肾和胰腺和其它同种型（α - 2）在脑，心脏和骨骼肌中表达表达。此同种型被确定为在患有费尔蒂综合症66％的自身抗原。该基因已被发现具有许多染色体多个副本，其中的一些，如果不是全部，代表不同的假基因。 [由RefSeq的，2008年7月提供]

OMIM数据库中对EEF1A1基因的介绍     Wikipedia数据库中对EEF1A1基因的介绍

基因序列

基因序列

EEF1A1基因的碱基序列：[NCBI]

基因突变

基因突变

EEF1A1基因的碱基突变：           显示全部snp
rs1128073       rs1390082       rs1874229       rs1874230       rs2073465       rs2073466       rs2291719       rs2351123       rs2351124       rs2882585       rs3757113       rs3806980       rs3806981       rs3822960       rs4302642       rs4708060       rs7751342       rs9442917       rs11340128       rs11550831       rs11550843       rs11556677       rs11755449       rs12111143       rs13193159       rs16883805       rs28365878       rs41265521       rs41501347       rs66831937       rs72961972       rs73452548       rs74551705       rs75478357       rs75811042       rs77163422       rs77323475      
rs78631420       rs78993679       rs79096499       rs112118568       rs112358938       rs113013917       rs113414349       rs113657688       rs114175855       rs114331680       rs114377034       rs114626730       rs115224400       rs115452014       rs115756680       rs116252278       rs116764008       rs116914658       rs137968211       rs138320387       rs138533046       rs139111321       rs139388407       rs139439943       rs139475137       rs139487221       rs139835813       rs140448519       rs140840660       rs141277092       rs141416343       rs141528307       rs142620389       rs143297587       rs143442302       rs143861012       rs143955203       rs144134045       rs144143413       rs144609902       rs145449215       rs145908746       rs146031026       rs146476537       rs146910786       rs147034609       rs147103543       rs147292801       rs147875793       rs148339214       rs148964987       rs149215139       rs149733797       rs149785977       rs150889591       rs150922924       rs181076483       rs181225703       rs182025032       rs182062425       rs182862632       rs183102689       rs183169180       rs183965550       rs184320582       rs184461155       rs184611265       rs185406225       rs185519638       rs185622540       rs185923006       rs186024837       rs186201572       rs186446616       rs187330951       rs187523336       rs187745352       rs187942524       rs188135961       rs188709185       rs189179228       rs189227667       rs189907516       rs190673282       rs190893068       rs191013141       rs191527753       rs192118435       rs192369875       rs192446229       rs192457288       rs192629107       rs192668234       rs193039260       rs199585879       rs199756686       rs199819622       rs199860345       rs199977965       rs200161893       rs200265404       rs200344550       rs200371831       rs200565926       rs200704078       rs200760061       rs200820708       rs200920964       rs200958501       rs201057606       rs201105030       rs201275258       rs201363695       rs201583180       rs201611945       rs201838097       rs201900429       rs201959385       rs202142846       rs202207658       rs267601114       rs367732942       rs368012545       rs368386743       rs369184719       rs369660080       rs369881201       rs370108040       rs370295050       rs370546611       rs370628692       rs370980757       rs371324554       rs372237769       rs372342500       rs372579366       rs373124203       rs373139783       rs373647495       rs374374947       rs374376904       rs375321701       rs375571173       rs375905062       rs376135900       rs376145722       rs376585892       rs376596299       rs376668805       rs377044681       rs377086995       rs377342040       rs377756744       rs527351503       rs527391186       rs528399233       rs528534612       rs528878907       rs529563428       rs529749380       rs529881423       rs530090499       rs530302960       rs531007027       rs531196610       rs531309435       rs531321585       rs531845372       rs532322462       rs533556344       rs533601560       rs534691194       rs534959176       rs534989474       rs535377863       rs535782447       rs535841231       rs535875224       rs535972306       rs536043151       rs537488179       rs538255514       rs538433417       rs538738926       rs539362323       rs539658193       rs539952985       rs540064883       rs540380222       rs540904347       rs541067582       rs541578183       rs541580152       rs542201496       rs542324896       rs542802719       rs542808392       rs543399978       rs543486874       rs544515226       rs544715817       rs545025904       rs545545535       rs545604322       rs546138681       rs546172016       rs547860837       rs547975242       rs548244542       rs548977009       rs549190139       rs549277159       rs549557322       rs550316813       rs550459409       rs550547029       rs550631790       rs551370213       rs551567396       rs552820563       rs552878006       rs552998475       rs553525890       rs554409799       rs555540179       rs555698355       rs556032192       rs556068423       rs556611408       rs556653424       rs556723534       rs557561811       rs557676047       rs557903705       rs558153819       rs558179239       rs559126325       rs559401377       rs559812793       rs559888220       rs559927403       rs560008137       rs560084399       rs560260702       rs560493203       rs561166847       rs562319421       rs562555393       rs562555908       rs562666593       rs562869644       rs562872308       rs562918025       rs563821772       rs564201050       rs565065758       rs565175087       rs565179765       rs566086561       rs566138226       rs566222157       rs566266273       rs566385503       rs566409747       rs566780946       rs567492289       rs567537060       rs568695269       rs568809360       rs568811842       rs568812459       rs568898136       rs569046122       rs569414898       rs569803110       rs570129661       rs570141088       rs570171124       rs570172859       rs571081675       rs571210896       rs571327046       rs571601832       rs572051508       rs572128006       rs572453895       rs572617510       rs573082895       rs573142704       rs573295095       rs574439551       rs574692065       rs574799653       rs574947176       rs574999371       rs575205465       rs575498397       rs575942425       rs576088694       rs576134698       rs576361374       rs577032960       rs577065951       rs577161022       rs577348109       rs577598766       rs577638464       rs577690988       rs577855693       rs745442779       rs745529662       rs745637124       rs745690302       rs745812014       rs746148578       rs746231854       rs746231902       rs746520771       rs746641100       rs746911417       rs746984821       rs747375852       rs747389797       rs747428272       rs747496389       rs747649461       rs747956704       rs748086900       rs748584832       rs748622712       rs748786375       rs748970608       rs749088326       rs749141367       rs749231086       rs749290541       rs749364818       rs749408207       rs749598148       rs749605132       rs750064090       rs750221943       rs750497846       rs750645385       rs750948223       rs751180416       rs751181708       rs751287870       rs751338833       rs751463252       rs751514664       rs751726911       rs751803453       rs751808342       rs752107734       rs752244727       rs752822715       rs752926143       rs752988254       rs753093429       rs753254791       rs753723666       rs753793599       rs754013401       rs754096369       rs754304691       rs754350604       rs754388054       rs754439602       rs754552807       rs754832249       rs754883638       rs755049275       rs755173732       rs755319175       rs755336923       rs755440209       rs755464353       rs755529377       rs755582392       rs756034816       rs756047931       rs756372821       rs756564928       rs756589297       rs756699997       rs756736257       rs756830892       rs756893560       rs756953818       rs757080023       rs757279395       rs757423811       rs757532692       rs758095585       rs758258749       rs758357582       rs758574169       rs758696967       rs758764222       rs759141680       rs759149550       rs759265569       rs759266056       rs759390442       rs759800146       rs760025377       rs760149810       rs760444467       rs760489800       rs760743287       rs760900111       rs760920996       rs761013523       rs761031884       rs761290827       rs761391281       rs761478115       rs761688955       rs761751003       rs761879548       rs762020262       rs762048309       rs762299245       rs762339785       rs762469714       rs762490792       rs762534009       rs762680978       rs763013395       rs763157134       rs763192828       rs763430850       rs763482096       rs763543689       rs763778850       rs763809568       rs763922423       rs764090095       rs764113857       rs764218393       rs764250709       rs764273716       rs764464376       rs764567471       rs764885926       rs765308797       rs765490163       rs765550117       rs765652215       rs765660917       rs765946803       rs766005085       rs766059116       rs766074201       rs766187782       rs766506427       rs766531459       rs766627841       rs766779907       rs766787655       rs766986248       rs767047172       rs767179744       rs767236502       rs767419821       rs767528509       rs767727880       rs767779314       rs768108285       rs768126863       rs768161561       rs768163263       rs768178036       rs768410214       rs768537501       rs768583690       rs768629175       rs768745046       rs769047471       rs769186546       rs769368740       rs769470673       rs769663205       rs769720612       rs769792094       rs769822046       rs770394870       rs770526323       rs770807676       rs770938912       rs771000095       rs771159492       rs771217053       rs771381359       rs771434273       rs771443621       rs771624013       rs771645556       rs771971121       rs772165099       rs772569323       rs772678947       rs772694021       rs772746899       rs772979729       rs773230145       rs773271015       rs773353165       rs773424255       rs773547791       rs773846189       rs774116380       rs774411485       rs774490838       rs774576189       rs774621081       rs774949353       rs774951848       rs775098348       rs775457677       rs775774223       rs775930383       rs776068625       rs776207569       rs776212459       rs776212621       rs776665070       rs776686082       rs776743997       rs776774360       rs776867290       rs776970559       rs777068548       rs777353040       rs777353298       rs777373625       rs777425489       rs777552446       rs777619680       rs777791185       rs778184777       rs778191996       rs778266425       rs778657176       rs778988441       rs779313076       rs779390048       rs779526389       rs779793115       rs779906464       rs779925520       rs780432554       rs780555901       rs780567363       rs780695588       rs781036975       rs781046198       rs781090817       rs781437801       rs781620988      

基因表达

基因表达

EEF1A1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTACTGTTCCTGTTCCGAG
58
CTTCCGTTGTAACGTTGAC
57
GCCATCTGATCTATAAATGCGG
60
GAGCCCTTTCCCATCTCAG
60
CCGACACAGTAGCATTTGTG
60
TTGAACCAAGGCATGTTAGC
59
GTCAAGGATGTTCGTCGTG
59
AGGATAATCACCTGAGCAGTG
60
CTGTCAAGGATGTTCGTCG
59
GGATAATCACCTGAGCAGTG
58
GGACATCTCAGGCTGACTG
60
TGCCCATTCTTGGAGATACC
60
GTCAAGGATGTTCGTCGTG
59
GGATAATCACCTGAGCAGTG
58
GGACATCTCAGGCTGACTG
60
GCCCATTCTTGGAGATACCA
60
CCATCTGATCTATAAATGCGGTG
59
GAGCCCTTTCCCATCTCAG
59
TACTGTTCCTGTTCCGAGTG
60
ACTTCCGTTGTAACGTTGAC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

EEF1A1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

EEF1A1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0003746
A0A087WV01(UniProtKB)
IEA
GO:0003924
A0A087WV01(UniProtKB)
IEA
GO:0005525
A0A087WV01(UniProtKB)
IEA
GO:0005737
A0A087WV01(UniProtKB)
IEA
GO:0006414
A0A087WV01(UniProtKB)
IEA
GO:0003924
A0A087WVQ9(UniProtKB)
IEA
GO:0005525
A0A087WVQ9(UniProtKB)
IEA
GO:0003924
A6PW80(UniProtKB)
IEA
GO:0005525
A6PW80(UniProtKB)
IEA
GO:0000049
P68104(UniProtKB)
IDA
GO:0003746
P68104(UniProtKB)
TAS
GO:0003924
P68104(UniProtKB)
IBA
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005515
P68104(UniProtKB)
IPI
GO:0005525
P68104(UniProtKB)
TAS
GO:0005615
P68104(UniProtKB)
IDA
GO:0005634
P68104(UniProtKB)
IDA
GO:0005634
P68104(UniProtKB)
IDA
GO:0005634
P68104(UniProtKB)
IDA
GO:0005634
P68104(UniProtKB)
IDA
GO:0005730
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
ISS
GO:0005737
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
TAS
GO:0005737
P68104(UniProtKB)
IDA
GO:0005737
P68104(UniProtKB)
IDA
GO:0005829
P68104(UniProtKB)
IDA
GO:0005829
P68104(UniProtKB)
TAS
GO:0005853
P68104(UniProtKB)
TAS
GO:0006351
P68104(UniProtKB)
IEA
GO:0006355
P68104(UniProtKB)
IEA
GO:0006414
P68104(UniProtKB)
TAS
GO:0006414
P68104(UniProtKB)
TAS
GO:0016020
P68104(UniProtKB)
IDA
GO:0019901
P68104(UniProtKB)
IPI
GO:0019901
P68104(UniProtKB)
IPI
GO:0030864
P68104(UniProtKB)
IDA
GO:0032587
P68104(UniProtKB)
IDA
GO:0044822
P68104(UniProtKB)
IDA
GO:0044822
P68104(UniProtKB)
IDA
GO:0070062
P68104(UniProtKB)
IDA
GO:0070062
P68104(UniProtKB)
IDA
GO:0070062
P68104(UniProtKB)
IDA
GO:0070062
P68104(UniProtKB)
IDA
GO:0070062
P68104(UniProtKB)
IDA
GO:0071364
P68104(UniProtKB)
IDA
GO:0098574
P68104(UniProtKB)
NAS
GO:1904714
P68104(UniProtKB)
NAS
GO:0005634
P68104(UniProtKB)
IDA
GO:0005634
P68104(UniProtKB)
IDA
GO:0003924
Q5JR01(UniProtKB)
IEA
GO:0005525
Q5JR01(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控EEF1A1基因的相关microRNA：      显示全部miRNA

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Animal Mammary Neoplasms 0.12 1 0 CTD_human
Mammary Neoplasms, Experimental 0.12 1 0 CTD_human
Stomach Neoplasms 0.12 1 0 CTD_human
Mycoplasma Infections 0.003810118 4 0 BeFree_LHGDN
Liver carcinoma 0.002995792 2 0 BeFree_LHGDN
Malignant neoplasm of prostate 0.001357209 5 0 BeFree
Prostate carcinoma 0.001357209 5 0 BeFree
Prostatic Neoplasms 0.000814326 3 0 BeFree
Carcinogenesis 0.000814326 3 0 BeFree
Wasting 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Colorectal Cancer 0.000542884 2 0 BeFree
Prostatic Hypertrophy 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Colorectal Neoplasms 0.000271442 1 0 BeFree
Cryptorchidism 0.000271442 1 0 BeFree
Inflammatory Bowel Diseases 0.000271442 1 0 BeFree
Leukodystrophy 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Seminoma 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 0 BeFree
Germ cell tumor 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Polymicrogyria 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Metastatic Prostate Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

没有相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2