DLX5(distal-less homeobox 5)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

7q21.3
基因染色体位置图

基因简述

基因简述

This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  这个基因编码同源框转录因子基因家族类同果蝇远侧少基因的一个成员。所编码的蛋白质可能在骨发育和骨折愈合的作用。这个基因，它位于一个尾对尾配置与家族的另一成员7号染色体长臂，突变可能与拆分手/拆分脚畸形有关。 [由RefSeq的，2008年7月提供]

OMIM数据库中对DLX5基因的介绍     Wikipedia数据库中对DLX5基因的介绍

基因序列

基因序列

DLX5基因的碱基序列：[NCBI]

基因突变

基因突变

DLX5基因的碱基突变：           显示全部snp
rs982346       rs1207731       rs1207732       rs1207733       rs1207734       rs1207735       rs3214218       rs3779213       rs3823753       rs6975750       rs7807332       rs9769385       rs10525881       rs10716251       rs12533469       rs28448553       rs35273378       rs61753628       rs73404541       rs73404545       rs73404547       rs73708842       rs73708843       rs75290158       rs75624442       rs76038366       rs79039650       rs79157781       rs79183163       rs79464991       rs111564934       rs112151546       rs112700442       rs115203738       rs115839710       rs116853924       rs117901163      
rs138650319       rs138911344       rs138986105       rs139553906       rs140462412       rs140706964       rs141521941       rs141713003       rs142492086       rs142581555       rs143231017       rs143377569       rs143457052       rs144772458       rs145643861       rs145966633       rs146762155       rs147255037       rs147363957       rs147529516       rs147904307       rs148111274       rs148422652       rs148894146       rs149635296       rs150240386       rs150540108       rs150866607       rs181026109       rs182525654       rs182671220       rs183375261       rs183501074       rs183831745       rs184168986       rs184335150       rs185135803       rs185246840       rs185529928       rs185939358       rs186251255       rs186612887       rs186955887       rs187102355       rs187254808       rs188114093       rs188575547       rs188830014       rs188916679       rs190257586       rs190382717       rs191665602       rs192168935       rs192266084       rs192864378       rs193211794       rs193302639       rs199567160       rs199678276       rs199725569       rs199916526       rs199945918       rs200209992       rs200468189       rs200799043       rs200820594       rs201233212       rs201376176       rs201666211       rs201841970       rs202152755       rs202245455       rs367692677       rs368239558       rs368292584       rs369530818       rs369562870       rs369817897       rs370171925       rs370400721       rs370973096       rs371127948       rs371372992       rs371922223       rs372558150       rs372846518       rs373248990       rs375295363       rs376161860       rs376279000       rs376488297       rs376636935       rs376879283       rs377762040       rs397692728       rs397812430       rs527362857       rs527440729       rs527706539       rs527963896       rs529621642       rs529675199       rs530280507       rs530677424       rs530738339       rs531221889       rs531938480       rs531950690       rs532092789       rs532345156       rs532759180       rs532843722       rs532868162       rs533107446       rs533167731       rs533894373       rs534021810       rs534291396       rs534933012       rs535229961       rs536691038       rs536947954       rs537005933       rs537065787       rs537210604       rs537332299       rs537812194       rs538340733       rs538807541       rs539535381       rs540083620       rs540632482       rs541052054       rs541098729       rs541457727       rs542407706       rs542685471       rs543448500       rs543540153       rs543706542       rs545429729       rs545645231       rs546456083       rs546551494       rs546855114       rs547131001       rs547453114       rs547809410       rs548274864       rs548902851       rs549202762       rs550934705       rs551728987       rs551868083       rs552911497       rs553342494       rs553535957       rs553730476       rs554250076       rs554720587       rs554983217       rs555064493       rs555118359       rs555252153       rs555922212       rs555985257       rs557248401       rs557455735       rs557696283       rs557917155       rs557978628       rs558974277       rs559321216       rs559759060       rs559930218       rs560150894       rs560281563       rs561473932       rs561594492       rs562135346       rs562271626       rs562464172       rs563327416       rs563336097       rs563471661       rs563982917       rs564458389       rs565338441       rs565547132       rs566002800       rs566477608       rs566490435       rs567202500       rs568436823       rs568621102       rs569280303       rs569516533       rs570754128       rs570956834       rs571532941       rs571601964       rs571835755       rs572013953       rs572221754       rs573302536       rs573756955       rs573820813       rs574247382       rs574692109       rs574872037       rs574961091       rs575908695       rs576705640       rs576971046       rs577459960       rs577855653       rs577959981       rs745325620       rs745330405       rs745523370       rs746277945       rs746404550       rs746833971       rs747048605       rs747164965       rs747497977       rs747524363       rs747888005       rs748080388       rs748192072       rs748382132       rs749209979       rs749333020       rs749467954       rs749709560       rs750016914       rs750148914       rs750391934       rs750674456       rs750677902       rs750933114       rs751038558       rs751182245       rs751332130       rs751513849       rs751602574       rs751606335       rs751835694       rs752314719       rs752650484       rs752961858       rs753085889       rs753398910       rs753621536       rs753795231       rs753811703       rs754104569       rs754218066       rs754410533       rs754590576       rs755399640       rs755697591       rs755969884       rs756242277       rs756300991       rs756330186       rs756666191       rs757262628       rs757335910       rs757374779       rs757774529       rs758348857       rs758485182       rs758672181       rs758818059       rs759221585       rs759444253       rs759489203       rs760216169       rs760475226       rs760699921       rs760840290       rs760894595       rs760947489       rs761160497       rs761431045       rs761561778       rs761722696       rs762108751       rs762312737       rs762435580       rs762498461       rs762671104       rs762883258       rs763009516       rs763057428       rs763398794       rs763425377       rs763609484       rs763893111       rs763909664       rs764265120       rs764373529       rs764653412       rs764890966       rs765089599       rs765696769       rs765735593       rs765748732       rs765808270       rs765898430       rs766080014       rs766476023       rs766857960       rs767009962       rs767020052       rs767417447       rs767630536       rs768147070       rs768389833       rs768462780       rs768590287       rs768877569       rs768983389       rs769322943       rs769554704       rs769677369       rs770097670       rs770665967       rs771384847       rs772392826       rs772537977       rs772549093       rs772980357       rs772981631       rs773641315       rs774125322       rs774345618       rs774697416       rs775382082       rs775574349       rs775634016       rs775776434       rs775940925       rs775952037       rs776056313       rs776137912       rs776399251       rs776425847       rs776445505       rs777486759       rs777701882       rs778003408       rs778509260       rs778599249       rs778847173       rs778952255       rs779237377       rs779599860       rs779616943       rs780335780       rs780431973       rs780601695       rs780878673       rs781358596       rs781456431      

基因表达

基因表达

DLX5基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTACGCTAGCTCCTACCAC
59
GGTCACTTCTTTCTCTGGC
58
GAAGACTCAGTACCTCGCC
59
ACCTGTGTTTGTGTCAATCC
58
CTACGCTAGCTCCTACCAC
59
GTCACTTCTTTCTCTGGCTG
58
AGAAGACTCAGTACCTCGC
58
ACCTGTGTTTGTGTCAATCC
58
TCAGAAGACTCAGTACCTCG
58
ACCTGTGTTTGTGTCAATCC
58
CTACGCTAGCTCCTACCAC
59
GGTCACTTCTTTCTCTGGCT
59

转录因子

转录因子

转录因子
影响类型
PubMed链接
IBSP
Activation
16000302
IBSP
Unknown
23485603
IGFBP3
Unknown
17278996
IRS2
Activation
21045156
MYC
Activation
19497851

基因本体信息

DLX5基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

DLX5基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000790
P56178(UniProtKB)
ISS
GO:0000978
P56178(UniProtKB)
ISS
GO:0001077
P56178(UniProtKB)
ISS
GO:0001501
P56178(UniProtKB)
TAS
GO:0001649
P56178(UniProtKB)
ISS
GO:0001958
P56178(UniProtKB)
ISS
GO:0005737
P56178(UniProtKB)
IEA
GO:0006366
P56178(UniProtKB)
IEA
GO:0007399
P56178(UniProtKB)
TAS
GO:0007411
P56178(UniProtKB)
IEA
GO:0008283
P56178(UniProtKB)
IDA
GO:0030326
P56178(UniProtKB)
IEA
GO:0030509
P56178(UniProtKB)
ISS
GO:0030855
P56178(UniProtKB)
IEA
GO:0042472
P56178(UniProtKB)
IEA
GO:0044212
P56178(UniProtKB)
IDA
GO:0045669
P56178(UniProtKB)
IEA
GO:0045893
P56178(UniProtKB)
IDA
GO:0048646
P56178(UniProtKB)
IEA
GO:0050679
P56178(UniProtKB)
IEA
GO:0060021
P56178(UniProtKB)
IEA
GO:0060166
P56178(UniProtKB)
IEA
GO:0060325
P56178(UniProtKB)
IEA
GO:0071773
P56178(UniProtKB)
ISS
GO:0071837
P56178(UniProtKB)
IEA
GO:0090263
P56178(UniProtKB)
IEA
GO:1901522
P56178(UniProtKB)
ISS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控DLX5基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Split-Hand/Foot Malformation With Sensorineural Hearing Loss 0.36 1 1 CLINVAR_ORPHANET_UNIPROT
Split hand foot deformity 1 0.201085767 4 2 BeFree_CLINVAR_MGD
Ectrodactyly 0.120814326 3 0 BeFree_ORPHANET
Craniofacial Abnormalities 0.120271442 4 0 BeFree_CTD_human
Bone Diseases, Developmental 0.12 1 0 CTD_human
Rett Syndrome 0.00408156 5 0 BeFree_LHGDN
Lung Neoplasms 0.00272435 1 0 LHGDN
Split-Hand/Foot Malformation 0.001357209 5 0 BeFree
Congenital Foot Deformity 0.000814326 3 0 BeFree
Autistic Disorder 0.000542884 2 0 BeFree
Cleft Palate 0.000542884 2 0 BeFree
T-Cell Lymphoma 0.000542884 2 0 BeFree
Malignant neoplasm of lung 0.000542884 2 0 BeFree
Leukemogenesis 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Congenital chromosomal disease 0.000271442 1 0 BeFree
Craniosynostosis 0.000271442 1 0 BeFree
Sensorineural Hearing Loss (disorder) 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Pierre Robin Syndrome 0.000271442 1 0 BeFree
Turner Syndrome 0.000271442 1 0 BeFree
Ovarian Failure, Premature 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Hearing Loss, Mixed Conductive-Sensorineural 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Limb defects 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Cancer Cell Growth 0.000271442 1 0 BeFree
Auriculo-condylar syndrome 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

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