DIO2(deiodinase, iodothyronine, type II) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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14q24.2-q24.3
基因染色体位置图

The protein encoded by this gene belongs to the iodothyronine deiodinase family. It activates thyroid hormone by converting the prohormone thyroxine (T4) by outer ring deiodination (ORD) to bioactive 3,3',5-triiodothyronine (T3). It is highly expressed in the thyroid, and may contribute significantly to the relative increase in thyroidal T3 production in patients with Graves disease and thyroid adenomas. This protein contains selenocysteine (Sec) residues encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于脱碘碘酶家族。它由外环脱碘(ORD)生物活性的3,3‘,5-三碘甲状腺氨酸(T3)转换激素原甲状腺素(T4)激活的甲状腺激素。它是在甲状腺中高表达,并可能在Graves病患者和甲状腺腺瘤甲状腺T3产量相对增加显著贡献。这种蛋白质包含由UGA密码子,通常信号翻译终止编码的硒代半胱氨酸(SEC)的残留物。含仲基因的3‘非编码区有一个共同的茎环结构,所述秒插入序列(SECIS),这是必要的识别UGA作为二段密码子,而不是作为一个停止信号。在多个转录剪接变异体导致编码不同亚型。 [由RefSeq的,2008年7月提供]

DIO2基因的碱基序列:[NCBI]
DIO2基因的碱基突变:           显示全部snp
rs190119       rs224995       rs225008       rs379237       rs1491505       rs1491506       rs1907526       rs4899766       rs4903905       rs7145153       rs7145584       rs7146189       rs7154177       rs7154898       rs7159642       rs7160310       rs7350729       rs8010760       rs8015989       rs9972105       rs9972275       rs10133463       rs10136505       rs10142136       rs10144099       rs10150064       rs10553303       rs10589235       rs11345521       rs11847987       rs12589204       rs12885300       rs12886364       rs17110449       rs17110461       rs17176545       rs17176580      
rs28491844       rs34382327       rs56356707       rs61989395       rs67721072       rs71103851       rs71416828       rs73335221       rs74064461       rs74064462       rs74958408       rs75009151       rs75449041       rs75505054       rs75647261       rs75649046       rs76212052       rs76507704       rs76624161       rs76844168       rs76880204       rs77041728       rs77247811       rs78000215       rs78457170       rs78670124       rs79951064       rs80075917       rs80191763       rs111753590       rs111959608       rs112126952       rs112594188       rs112911546       rs113344856       rs113942472       rs114144820       rs114146658       rs114339253       rs114478474       rs114483990       rs114947328       rs115261103       rs115481802       rs115748779       rs115906974       rs115920106       rs116178577       rs116267583       rs116322626       rs116405919       rs116574888       rs116718532       rs117043662       rs117085347       rs117159269       rs117192515       rs117327866       rs117496584       rs117708983       rs118079983       rs137973850       rs138025570       rs138246208       rs138303018       rs138634895       rs138722008       rs138823454       rs138955911       rs139136833       rs139388239       rs139395860       rs139520196       rs139532857       rs139628438       rs139992932       rs140124641       rs140363660       rs140827318       rs141062659       rs141144534       rs141280131       rs141300126       rs141641501       rs141737290       rs141747612       rs141777460       rs141820253       rs141859549       rs142396637       rs142411929       rs142607784       rs142693560       rs142775233       rs143119179       rs143134365       rs143244467       rs143437139       rs143744934       rs143829326       rs143873843       rs143981308       rs144306036       rs144961880       rs145311923       rs145421760       rs145510353       rs145536356       rs145575928       rs145862415       rs146272451       rs146283738       rs146534904       rs146583943       rs147288969       rs147344227       rs147742289       rs147752010       rs147913011       rs148277935       rs148623873       rs148630588       rs148781807       rs148938273       rs149094137       rs149251866       rs149367036       rs149525841       rs149864798       rs150177415       rs150186652       rs150239624       rs150500443       rs150554032       rs150912635       rs150955267       rs151236591       rs151289518       rs181112773       rs181363619       rs181367110       rs181369623       rs181417523       rs181639226       rs181843191       rs181961696       rs182088628       rs182245101       rs182379757       rs182396398       rs182671801       rs182810471       rs182926549       rs183214892       rs183398425       rs183545102       rs183683448       rs183707832       rs184017434       rs184031928       rs184037515       rs184419510       rs184578432       rs184583629       rs184728198       rs185012124       rs185068033       rs185186885       rs185345161       rs185413101       rs185707383       rs185749149       rs186030816       rs186043870       rs186251654       rs186334207       rs186463528       rs186692464       rs186779754       rs186930239       rs187074264       rs187218995       rs187404762       rs187612190       rs187681519       rs187998637       rs188372043       rs188751781       rs188764247       rs188901693       rs188997423       rs189064366       rs189129935       rs189264674       rs189399450       rs189411453       rs189555139       rs189802176       rs189905903       rs190013770       rs190146403       rs190645446       rs190957902       rs190976974       rs191317041       rs191338317       rs191437113       rs191455789       rs191477357       rs191743086       rs191893719       rs191972790       rs192197838       rs192350929       rs192841980       rs192877994       rs193246610       rs200390046       rs200506351       rs200630859       rs200978509       rs201987565       rs367557390       rs367669584       rs368089479       rs368405273       rs368727480       rs369293653       rs369342438       rs369348820       rs370759186       rs371205072       rs371569399       rs372468373       rs372927096       rs373299346       rs373582488       rs373939390       rs374224407       rs374814085       rs376291377       rs376318713       rs376732148       rs377469634       rs377568661       rs527687147       rs527691779       rs528296338       rs528344368       rs528367596       rs528727854       rs528790875       rs529027453       rs529037327       rs529097558       rs529150980       rs529162255       rs529209148       rs529583282       rs529726859       rs529827916       rs530201640       rs530299654       rs530392277       rs530488249       rs530529738       rs530586982       rs530649472       rs531012351       rs531021446       rs531072248       rs531082328       rs531195605       rs531545689       rs531743498       rs531794113       rs531814376       rs531868319       rs531929505       rs531973500       rs532622396       rs532682640       rs532797050       rs533024451       rs533696554       rs533729315       rs533767167       rs533768086       rs534075225       rs534141087       rs534464588       rs534477443       rs534629130       rs534682374       rs534719386       rs534776847       rs534832769       rs534953798       rs535060851       rs535127774       rs535221639       rs535224740       rs535278348       rs535314444       rs535446905       rs535517928       rs535545070       rs535607597       rs535818341       rs536068521       rs536130379       rs536333155       rs536543263       rs537137471       rs537248898       rs537477709       rs537668797       rs538130351       rs538478635       rs538974187       rs539085991       rs539251276       rs539251314       rs539505883       rs539731427       rs539801238       rs539920648       rs540174584       rs540365239       rs540486144       rs540677126       rs540849236       rs540908176       rs540962070       rs541050418       rs541104235       rs541445180       rs541492653       rs541539367       rs541768032       rs541826144       rs542365723       rs542613924       rs542800452       rs542825960       rs542874079       rs542887445       rs542909521       rs543341487       rs543436283       rs543449855       rs543599446       rs543699399       rs544160772       rs544381742       rs544440503       rs544512733       rs545149964       rs545239035       rs545302144       rs545309109       rs545345134       rs545468797       rs545557489       rs546031455       rs546231976       rs546267060       rs546382456       rs546443850       rs546591946       rs546927622       rs547105883       rs547125652       rs547189022       rs547488606       rs547506050       rs547740385       rs548519686       rs548695620       rs548924599       rs549031709       rs549055638       rs549117121       rs549138190       rs549199707       rs549582811       rs549599800       rs549663022       rs549675911       rs550212385       rs550392405       rs550599606       rs550803613       rs551037940       rs551124172       rs551371351       rs551596634       rs551914138       rs552153460       rs552517987       rs553191654       rs553359888       rs553367182       rs553401233       rs553771001       rs554190056       rs554371799       rs554444702       rs554505967       rs554559737       rs554716237       rs554779972       rs554957175       rs555160304       rs555309608       rs555310472       rs555370978       rs555389118       rs555645300       rs555833334       rs555850256       rs555911638       rs555927180       rs556017415       rs556103930       rs556142978       rs556461404       rs556524932       rs556823789       rs556902304       rs556915403       rs556966300       rs557041488       rs557370072       rs557504950       rs557709616       rs557760999       rs557841175       rs557902811       rs558108731       rs558587200       rs558836705       rs558934645       rs559323668       rs559515680       rs559563994       rs559599553       rs559623901       rs559704075       rs560053621       rs560530767       rs560531271       rs560582530       rs560635197       rs560654455       rs560699523       rs560785669       rs560886603       rs561043075       rs561247931       rs561311196       rs561513639       rs561568132       rs561733116       rs562044404       rs562090693       rs562163446       rs562882823       rs563080002       rs563090624       rs563322144       rs563378889       rs563738946       rs564179720       rs564250321       rs564848503       rs565057973       rs565121425       rs565257800       rs565458939       rs565662148       rs565864794       rs565923921       rs565931600       rs566385644       rs566727324       rs566875184       rs566929923       rs566939045       rs566993499       rs567249054       rs567603831       rs567664049       rs567668764       rs567762318       rs568306890       rs568597358       rs569074926       rs569087094       rs569256286       rs569667357       rs569929485       rs570147858       rs570206055       rs570243526       rs570685629       rs571025592       rs571153581       rs571197056       rs571319982       rs571383490       rs571551760       rs571730058       rs571731761       rs571944276       rs572005675       rs572066498       rs572241114       rs573082264       rs573144951       rs573151253       rs573745096       rs573880262       rs573958593       rs574002475       rs574448181       rs574698897       rs574814888       rs574839051       rs575150110       rs575271219       rs575278142       rs575336984       rs575626392       rs575938007       rs575987361       rs576433579       rs576484812       rs576517577       rs576561284       rs576760162       rs576904641       rs576960794       rs577002242       rs577298750       rs577506082       rs577569417       rs577629729       rs577669411       rs577733497       rs577743008       rs745698739       rs748352145       rs748438251       rs749389382       rs749477268       rs750827588       rs750873030       rs751916610       rs753845745       rs755048207       rs755131907       rs756525368       rs756684593       rs758690610       rs759579808       rs760453325       rs760473799       rs762568192       rs762655591       rs767741367       rs769802439       rs770622026       rs772940975       rs774131479       rs775092695       rs775453125       rs776430937       rs776541312       rs779024875       rs779114709       rs779952827       rs780810869       rs172801       rs184416       rs225010       rs225011       rs225012       rs225013       rs225014       rs225015       rs225016       rs225017       rs225018       rs225019       rs225020       rs1056811       rs1056813       rs1056817       rs1388378       rs1491496       rs2267872       rs2267873       rs2839858       rs2839859       rs5809988       rs6574549       rs6574550       rs6574551       rs7140952       rs8009555       rs10136454       rs12437279       rs17110436       rs28465207       rs34013456       rs34406136       rs56033314       rs73333393       rs73335219       rs74064459       rs74471473       rs75196191       rs76492270       rs76977648       rs77075531       rs77388857       rs77699897       rs78436270       rs78527313       rs78666376       rs112366601       rs112495571       rs112683136       rs113550815       rs115038813       rs116148669       rs116231852       rs116239203       rs116508894       rs117227895       rs117519293       rs138247181       rs138405185       rs138488543       rs138580646       rs138823454       rs139953847       rs140271372       rs140291641       rs140743723       rs142177250       rs143144220       rs143186712       rs143415177       rs144069565       rs144177237       rs144435120       rs144696064       rs144718494       rs144870997       rs145808483       rs146653501       rs146702334       rs147405255       rs147449827       rs147492488       rs147814825       rs148372750       rs148684063       rs149059509       rs149191033       rs149348198       rs149927989       rs150616232       rs151008680       rs180882142       rs181277125       rs181554842       rs181652125       rs182375159       rs182674111       rs182952416       rs183228668       rs184180480       rs184218920       rs184257454       rs184541438       rs184719105       rs184864306       rs185723825       rs185882272       rs186063648       rs186794219       rs187037837       rs187265220       rs187354335       rs188047180       rs188765140       rs188922024       rs189066374       rs189260678       rs189625988       rs190440469       rs190834952       rs191213207       rs191264131       rs191898733       rs191935124       rs192106208       rs192334437       rs192607302       rs193055167       rs193087116       rs200301817       rs200899107       rs200970887       rs201270426       rs201964819       rs367784864       rs368731809       rs368821590       rs369318589       rs369888390       rs370868595       rs371030555       rs372137765       rs372664056       rs372827198       rs373497754       rs374310345       rs374704917       rs374883683       rs376013664       rs376459152       rs377081861       rs377114990       rs377366119       rs527290614       rs527819289       rs528357819       rs529361804       rs529851449       rs529912499       rs529977758       rs530777541       rs531136120       rs531259167       rs531326069       rs531995896       rs532066207       rs532124990       rs532331331       rs532649606       rs532855611       rs533167008       rs533344208       rs534525612       rs534745582       rs535035402       rs535293913       rs535338629       rs536143209       rs536199418       rs536260409       rs536327523       rs536327674       rs536390334       rs536454639       rs536518654       rs536772267       rs536842584       rs536859842       rs537176855       rs537529579       rs538193125       rs538315879       rs538377370       rs538630562       rs538726172       rs538788468       rs539747234       rs539994350       rs540499072       rs540578912       rs540630734       rs540818555       rs541270497       rs541408350       rs541553448       rs541713349       rs542523855       rs542633360       rs542651371       rs542696540       rs542696691       rs543151349       rs543495692       rs544227945       rs544442455       rs545013528       rs545073562       rs545447069       rs546297221       rs546516296       rs546653452       rs546830577       rs546870219       rs547319156       rs547550228       rs548697490       rs548757807       rs548845517       rs548907384       rs548968884       rs549993336       rs550520855       rs550752379       rs551239943       rs551302522       rs551628128       rs551848718       rs551909343       rs552164270       rs552580606       rs552954648       rs552960531       rs553119839       rs553164065       rs553741474       rs553834317       rs554894918       rs554957237       rs555018260       rs556084006       rs556178710       rs556355831       rs557076103       rs557166658       rs557227983       rs557304889       rs557547315       rs557565836       rs557886631       rs558103740       rs558165352       rs558425722       rs558488767       rs558748467       rs559007527       rs559030191       rs559410606       rs559665337       rs559716542       rs560204463       rs560361906       rs561043503       rs561096677       rs561376120       rs562044404       rs562226403       rs562293900       rs562514166       rs563183322       rs563622669       rs563859298       rs563899570       rs564677383       rs564738665       rs564976614       rs565192099       rs565252774       rs565330426       rs565523223       rs565586477       rs566200790       rs566522172       rs567041776       rs567250218       rs567436898       rs567557446       rs567680756       rs568496239       rs568571134       rs568806377       rs568819927       rs568962031       rs569320200       rs569339110       rs569667357       rs570739191       rs570970034       rs571403465       rs571628510       rs571770229       rs572660498       rs572801391       rs573184903       rs573213420       rs573654276       rs573873545       rs573935457       rs574746067       rs574871351       rs575575218       rs575690031       rs575875057       rs577022210       rs577049731       rs577327640       rs577545815       rs578047160       rs578107495       rs745385180       rs745403963       rs745611080       rs745958711       rs746354453       rs746448402       rs746452755       rs746553364       rs747185919       rs747400822       rs747497023       rs747589137       rs748161148       rs748252559       rs748260528       rs748487658       rs748654165       rs748944597       rs748959744       rs749129384       rs749319264       rs749347283       rs749866953       rs750345923       rs750567166       rs750658923       rs750718171       rs750739679       rs750847023       rs751154248       rs751533921       rs751691317       rs752004746       rs752191150       rs752203998       rs752282810       rs752484940       rs752574854       rs753041722       rs753199797       rs753317257       rs754283070       rs754607013       rs754624456       rs754813109       rs755440499       rs755561746       rs756437198       rs756450538       rs757180288       rs757370182       rs757538664       rs758221146       rs758224695       rs758722588       rs758833101       rs758926851       rs758976363       rs759273588       rs759489633       rs759909930       rs760217727       rs760429612       rs760563686       rs760853066       rs761515483       rs761956184       rs762084709       rs762384152       rs762767888       rs763014892       rs763218486       rs763409434       rs763675188       rs763735653       rs764684757       rs764872574       rs765121680       rs765667555       rs765759364       rs766090858       rs766634398       rs766645776       rs766733737       rs767210617       rs767367484       rs767607931       rs767611570       rs768610342       rs768655783       rs768743801       rs768863212       rs768885744       rs768976300       rs769049241       rs769341239       rs769378214       rs769471246       rs769748179       rs769990672       rs770068262       rs770130685       rs770472829       rs771121731       rs771606004       rs771690009       rs771829080       rs772180266       rs772236033       rs772484692       rs772652756       rs772714324       rs772732016       rs773223512       rs773379888       rs773864193       rs773948064       rs774136099       rs774557427       rs774913806       rs775294933       rs775597093       rs775882497       rs775939448       rs776352519       rs776372674       rs776462953       rs776624320       rs776814585       rs776993197       rs777313943       rs777896039       rs778251642       rs778343483       rs778446653       rs778815842       rs779026727       rs779294368       rs779464951       rs779674400       rs780435147       rs780531480       rs780627135       rs780650637       rs780740869       rs781293606       rs781489540       rs781553936       rs781661426       rs781728244      

DIO2基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GCAAATTCTGCCACCTTCC
60
AGCCTCATCAATGTAGACCAG
60
AAAGAAAGGGTAGCCTGGA
58
TGGGAGGTATGAGCATTCTC
59
CTACAAACAGGTGAAATTGGGT
59
ACTGTTGTCACCTCCTTCTG
60
GCAAATTCTGCCACCTTCC
60
GAGCCTCATCAATGTAGACCA
60
GCAGATGTGAGGACTTTGG
59
TCACAGTGTCCGTAGTTGG
59
GATTTATGGATGACTGACAGTG
57
CAGCTGCAGAATTCTTTCC
57
ACAAACAGCTAAATTGTCCTCC
59
TGTGAGTAGACCAGTAGTCTG
58
CTAAATTGTCCTCCATCAGGT
58
ACAACACTGTCAGTCATCC
57
CTACAAACAGGTGAAATTGGGT
59
ACTGTTGTCACCTCCTTCTG
60
TTGCTCAAGAGGGTGAAGG
60
AAGTCTACGCTGAGGATGC
60
      尚未收录相关数据

DIO2基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

DIO2基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004800
A0A0A0MTQ2(UniProtKB)
IEA
GO:0042404
A0A0A0MTQ2(UniProtKB)
IEA
GO:0042446
A0A0A0MTQ2(UniProtKB)
IEA
GO:0055114
A0A0A0MTQ2(UniProtKB)
IEA
GO:0004800
G3V3A8(UniProtKB)
IEA
GO:0016021
G3V3A8(UniProtKB)
IEA
GO:0042446
G3V3A8(UniProtKB)
IEA
GO:0055114
G3V3A8(UniProtKB)
IEA
GO:0004800
J3KQY5(UniProtKB)
IEA
GO:0042446
J3KQY5(UniProtKB)
IEA
GO:0055114
J3KQY5(UniProtKB)
IEA
GO:0001514
Q92813(UniProtKB)
NAS
GO:0004800
Q92813(UniProtKB)
IDA
GO:0004800
Q92813(UniProtKB)
TAS
GO:0004800
Q92813(UniProtKB)
TAS
GO:0005886
Q92813(UniProtKB)
TAS
GO:0006590
Q92813(UniProtKB)
TAS
GO:0006590
Q92813(UniProtKB)
TAS
GO:0008430
Q92813(UniProtKB)
IC
GO:0016020
Q92813(UniProtKB)
IC
GO:0016021
Q92813(UniProtKB)
IEA
GO:0031625
Q92813(UniProtKB)
IPI
GO:0042403
Q92813(UniProtKB)
IDA
GO:0042446
Q92813(UniProtKB)
IEA
GO:0055114
Q92813(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控DIO2基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Child Development Disorders, Pervasive 0.12 1 0 CTD_human
Endometriosis 0.12 1 0 CTD_human
Mesothelioma 0.12 1 0 CTD_human
Thyroid Diseases 0.12 1 0 CTD_human
Hypertensive disease 0.010096888 3 0 BeFree_GAD_LHGDN
Degenerative polyarthritis 0.009087065 7 1 BeFree_GAD_LHGDN
Diabetes Mellitus, Non-Insulin-Dependent 0.008544182 5 1 BeFree_GAD_LHGDN
Insulin Resistance 0.004734064 2 0 GAD
Graves Disease 0.003452799 4 1 BeFree_GAD
Hypothyroidism 0.003452799 4 1 BeFree_GAD
Thyroid Neoplasm 0.002995792 2 0 BeFree_LHGDN
Mental Retardation 0.002909916 2 0 BeFree_GAD
Obesity 0.002909916 3 1 BeFree_GAD
Choriocarcinoma 0.00272435 1 0 LHGDN
Euthyroid Sick Syndromes 0.00272435 1 0 LHGDN
Polyostotic fibrous dysplasia 0.00272435 1 0 LHGDN
Pituitary Neoplasms 0.00272435 1 0 LHGDN
Intellectual Disability 0.00272435 1 0 LHGDN
Bipolar Disorder 0.002638474 1 0 BeFree_GAD
Metabolic Syndrome X 0.002638474 1 1 BeFree_GAD
Endocrine System Diseases 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Major Depressive Disorder 0.002367032 1 0 GAD
Osteoarthritis of hip 0.000542884 2 2 BeFree
Kashin-Beck Disease 0.000542884 2 5 BeFree
Goiter 0.000271442 1 0 BeFree
Lipodystrophy 0.000271442 1 0 BeFree
Thyroid Gland Follicular Adenoma 0.000271442 1 0 BeFree
Follicular thyroid carcinoma 0.000271442 1 0 BeFree
Papillary thyroid carcinoma 0.000271442 1 0 BeFree
Osteoarthritis of the hand 0.000271442 1 0 BeFree
Osteoarthritis of distal interphalangeal joint 0.000271442 1 0 BeFree
Thyroid carcinoma 0.000271442 1 0 BeFree
Cardiomyopathies 0.000271442 1 0 BeFree
Lipoatrophy 0.000271442 1 0 BeFree
Differentiated Thyroid Gland Carcinoma 0.000271442 1 0 BeFree
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