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This gene is a member of the type IV diacylglycerol kinase subfamily. Diacylglycerol kinases regulate the intracellular concentration of diacylglycerol through its phosphorylation, producing phosphatidic acid. The specific role of the enzyme encoded by this gene is undetermined, however, it may play a crucial role in the production of phosphatidic acid in the retina or in recessive forms of retinal degeneration. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  该基因是IV型二酰基甘油激酶亚家族的一个成员。二酰基甘油激酶调节二酰基甘油的胞内浓度通过其磷酸化,产生磷脂酸。由该基因编码的酶的具体作用是未确定的,但是,它可能在生产中的视网膜磷脂酸或在视网膜变性的隐性形式发挥至关重要的作用。 [由RefSeq的,2008年7月提供]
DGKI基因(以及对应的蛋白质)的细胞分布位置:
DGKI基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Acquired Immunodeficiency Syndrome | 0.122367032 | 1 | 1 | GAD_GWASCAT |
Schizophrenia | 0.122367032 | 2 | 1 | GAD_GWASCAT |
Bipolar Disorder | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Dyslexia | 0.000271442 | 1 | 0 | BeFree |
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