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This gene encodes a zinc finger domain-containing protein that functions as a regulator of transcription. The encoded proteins binds to its own promoter as well as to that of several target genes. Activity of this protein is important in the regulation of embryonic development. Mutations in this gene have been found in individuals with autosomal dominant mental retardation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
[中文简述(自动翻译):]  这个基因编码锌指结构域的蛋白,其功能是作为转录的调节器。编码的蛋白质结合到其自身的启动子,以及该多个靶基因。该蛋白质的活性是在胚胎发育的调节很重要的。这个基因的突变与常染色体?个人被发现ominant智力低下。选择性剪接结果在多个抄本变形。 [由RefSeq的,2014年6月提供]
DEAF1基因(以及对应的蛋白质)的细胞分布位置:
DEAF1基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Intellectual Disability | 0.120542884 | 3 | 0 | BeFree_CTD_human |
| MENTAL RETARDATION, AUTOSOMAL DOMINANT 24 | 0.12 | 2 | 0 | UNIPROT |
| Diabetes Mellitus, Insulin-Dependent | 0.000542884 | 2 | 0 | BeFree |
| Unipolar Depression | 0.000542884 | 2 | 0 | BeFree |
| Speech impairment | 0.000542884 | 2 | 0 | BeFree |
| Major Depressive Disorder | 0.000542884 | 2 | 0 | BeFree |
| Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
| Mental disorders | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Diabetes | 0.000271442 | 1 | 0 | BeFree |
| Diabetes Mellitus | 0.000271442 | 1 | 0 | BeFree |
| Hyperglycemia | 0.000271442 | 1 | 0 | BeFree |
| Panic Disorder | 0.000271442 | 1 | 0 | BeFree |
| Tuberculosis | 0.000271442 | 1 | 0 | BeFree |
| Mood Disorders | 0.000271442 | 1 | 0 | BeFree |
| Attention deficit hyperactivity disorder | 0.000271442 | 1 | 0 | BeFree |
| Adenocarcinoma of large intestine | 0.000271442 | 1 | 0 | BeFree |
| Depression and Suicide | 0.000271442 | 1 | 0 | BeFree |
| PANIC DISORDER 1 | 0.000271442 | 1 | 0 | BeFree |
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