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The protein encoded by this gene is a member of the PAR bZIP transcription factor family and binds to specific sequences in the promoters of several genes, such as albumin, CYP2A4, and CYP2A5. The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014]
[中文简述(自动翻译):]  由该基因编码的蛋白质是PAR bZIP类转录因子家族的成员,并结合在多个基因,如白蛋白,CYP2A4和CYP2A5的启动子的特异性序列。所编码的蛋白质能结合DNA作为均聚物或异二聚体,并且涉及一些昼夜节律的基因的调节。 [由RefSeq的,2014年7月提供]
DBP基因(以及对应的蛋白质)的细胞分布位置:
DBP基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Diabetes Mellitus, Insulin-Dependent | 0.00764398 | 3 | 0 | BeFree_GAD |
Bipolar Disorder | 0.007101096 | 3 | 0 | GAD |
Obesity | 0.003724241 | 5 | 0 | BeFree_GAD |
Osteoporosis | 0.003452799 | 5 | 0 | BeFree_GAD |
Epilepsy, Temporal Lobe | 0.00272435 | 1 | 0 | LHGDN |
Chronic Obstructive Airway Disease | 0.002638474 | 2 | 0 | BeFree_GAD |
Multiple Sclerosis | 0.002638474 | 2 | 0 | BeFree_GAD |
Mental Depression | 0.002367032 | 1 | 0 | GAD |
Pathological fracture | 0.002367032 | 1 | 0 | GAD |
Kidney Failure, Chronic | 0.002367032 | 1 | 0 | GAD |
Osteoporosis, Postmenopausal | 0.002367032 | 1 | 0 | GAD |
Schizophrenia | 0.002367032 | 1 | 0 | GAD |
Sleep Disorders | 0.002367032 | 1 | 0 | GAD |
Hypertensive disease | 0.001357209 | 5 | 0 | BeFree |
Autoimmune Diseases | 0.000542884 | 2 | 0 | BeFree |
Diabetes Mellitus | 0.000542884 | 2 | 0 | BeFree |
Diabetes Mellitus, Non-Insulin-Dependent | 0.000542884 | 2 | 0 | BeFree |
Graves Disease | 0.000542884 | 2 | 0 | BeFree |
Overweight | 0.000542884 | 2 | 0 | BeFree |
Liver carcinoma | 0.000542884 | 2 | 0 | BeFree |
Anxiety Disorders | 0.000271442 | 1 | 0 | BeFree |
Arthritis | 0.000271442 | 1 | 0 | BeFree |
Rheumatoid Arthritis | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of urinary bladder | 0.000271442 | 1 | 0 | BeFree |
Hemophilia B | 0.000271442 | 1 | 0 | BeFree |
Diabetes | 0.000271442 | 1 | 0 | BeFree |
Diabetic Nephropathy | 0.000271442 | 1 | 0 | BeFree |
Glioma | 0.000271442 | 1 | 0 | BeFree |
Hepatitis B | 0.000271442 | 1 | 0 | BeFree |
Herpes Simplex Infections | 0.000271442 | 1 | 0 | BeFree |
Hyperglycemia | 0.000271442 | 1 | 0 | BeFree |
Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Degenerative polyarthritis | 0.000271442 | 1 | 0 | BeFree |
Ankylosing spondylitis | 0.000271442 | 1 | 0 | BeFree |
Stress, Psychological | 0.000271442 | 1 | 0 | BeFree |
Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
Uveitis | 0.000271442 | 1 | 0 | BeFree |
alpha 1-Antitrypsin Deficiency | 0.000271442 | 1 | 0 | BeFree |
Gitelman Syndrome | 0.000271442 | 1 | 0 | BeFree |
Intraocular pressure disorder | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
Cerebral Ischemia | 0.000271442 | 1 | 0 | BeFree |
Precursor B-cell lymphoblastic leukemia | 0.000271442 | 1 | 0 | BeFree |
Mammary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
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