CYP3A4基因详情-基因数据库-基因云馆

CYP3A4(cytochrome P450, family 3, subfamily A, polypeptide 4) 转至新版数据库

基因简称(symbol)

CYP3A4 [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

基因家族代码(gene_family_id)

862 [HGNC] [GenScript]

omim代码

124010

entrez码

1576 [Vega]

vega基因码

OTTHUMG00000156651

ensembl基因码

ENSG00000160868 [Ensembl]

基因家族(gene family)

Cytochrome P450s

refseq数据库代号

NM_001202855

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

07q21.1

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1990-02-24T00:00:00Z

基因简称更名时间(date_symbol_changed)

基因名称更名时间(date_name_changed)

2003-01-14T00:00:00Z

更新时间(date_modified)

2014-11-19T00:00:00Z

ucsc码

uc003urv.2

ena

AF280107

ccds数据码

CCDS5674

uniprot数据码

P08684

pubmed代码

8269949|1391968

mgd码

rgd码

RGD:708379

生命科学数据库(lsdb)

Human Cytochrome P450 (CYP) Allele Nomenclature Committee|http://www.cypalleles.ki.se/

更新时间(date modified)

2014-11-19T00:00:00Z

cosmic

CYP3A4

mirbase

基因曾用简称(prev symbol)

CYP3A3

基因曾用名称(prev name)

cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4

homeodb

cosmic

CYP3A4

snornabase

bioparadigms slc

orphanet

假基因信息(pseudogeneorg)

horde id

merops

imgt

iuphar

objectId:1337

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

1.1.1.161

中间纤维数据库

收起

7q21.1

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]

[中文简述(自动翻译):] 该基??因编码的酶的细胞色素P450超家族的成员。细胞色素P450蛋白是催化涉及药物代谢和胆固醇，类固醇和其他脂类的合成许多反应单加氧酶。此蛋白质定位于内质网和它的表达是由糖皮质激素和某些药理学药剂诱导的。这种酶是参与的大约一半在目前使用的药物，包括对乙酰氨基酚，可待因，环孢菌素A，地西泮和红霉素的代谢。酶还代谢一些类固醇和致癌物质。这种基因是细胞色素P450基因在染色体7q21.1群集的一部分。此前另一CYP3A基因??CYP3A3，被认为存在;然而，它现在认为这个序列表示CYP3A4的转录变异体。编码不同同种型的可变剪接转录物变体也已确定。 [由RefSeq的，2011年2月提供]

OMIM数据库中对CYP3A4基因的介绍 Wikipedia数据库中对CYP3A4基因的介绍

CYP3A4基因的碱基序列：[NCBI]

CYP3A4基因的碱基突变：显示全部snp

rs1041966 rs1041988 rs1800713 rs1851426 rs2242480 rs2246709 rs2253493 rs2404767 rs2405181 rs2405184 rs2687105 rs2687107 rs2687110 rs2687112 rs2687114 rs2687115 rs2687116 rs2687117 rs2687118 rs2687119 rs2687120 rs2687121 rs2687122 rs2687123 rs2687124 rs2687125 rs2687126 rs2738258 rs2738259 rs2738260 rs2738261 rs2738262 rs2740573 rs2740574 rs2740578 rs2740579 rs2740580

rs3091339 rs3091340 rs3208360 rs3208361 rs3208363 rs3735451 rs3800957 rs3914984 rs4281055 rs4602816 rs4646437 rs4646438 rs4646440 rs4986907 rs4986908 rs4986909 rs4986910 rs4986911 rs4986912 rs4986913 rs4986914 rs4987159 rs4987160 rs4987161 rs6956344 rs6957392 rs6975773 rs7801671 rs10250778 rs10264769 rs10267228 rs10270146 rs11432957 rs11773597 rs12114000 rs12333983 rs12670850 rs12721617 rs12721618 rs12721619 rs12721620 rs12721621 rs12721622 rs12721623 rs12721624 rs12721625 rs12721626 rs12721627 rs12721628 rs12721629 rs12721631 rs12721632 rs12721633 rs12721634 rs12721635 rs12721636 rs12721637 rs17161857 rs17161886 rs17161888 rs17161890 rs28371753 rs28371756 rs28371757 rs28371758 rs28371759 rs28371762 rs28371763 rs28907268 rs28907269 rs28908768 rs28908769 rs28969391 rs28988568 rs28988569 rs28988570 rs28988571 rs28988572 rs28988573 rs28988574 rs28988575 rs28988576 rs28988577 rs28988578 rs28988579 rs28988580 rs28988581 rs28988582 rs28988583 rs28988584 rs28988585 rs28988586 rs28988587 rs28988588 rs28988589 rs28988590 rs28988591 rs28988592 rs28988593 rs28988594 rs28988595 rs28988596 rs28988597 rs28988598 rs28988599 rs28988600 rs28988601 rs28988602 rs28988603 rs28988604 rs28988606 rs28988607 rs28988608 rs28988609 rs33972239 rs34047379 rs34088317 rs34141638 rs34166832 rs34186330 rs34248747 rs34309648 rs34314536 rs34363031 rs34382314 rs34469568 rs34642455 rs34703484 rs34738177 rs34784390 rs34823876 rs34853336 rs34898870 rs34932363 rs35030507 rs35073169 rs35172000 rs35173968 rs35211223 rs35223458 rs35379756 rs35384793 rs35389889 rs35494189 rs35564277 rs35587942 rs35596970 rs35599367 rs35723517 rs35864213 rs35937779 rs36010809 rs36082424 rs36231115 rs36231117 rs41280947 rs55671128 rs55785340 rs55808838 rs55901263 rs55913187 rs55951658 rs56153749 rs56187094 rs56324128 rs56357996 rs56997749 rs57409622 rs58256382 rs59038895 rs59418896 rs59503174 rs59537101 rs59715127 rs59759247 rs60535349 rs67206348 rs67784355 rs68106838 rs71528515 rs71534263 rs71581992 rs71581996 rs71581997 rs71582001 rs71582002 rs72258732 rs72494460 rs72552794 rs72552798 rs72552799 rs72552800 rs72556516 rs73156631 rs74345875 rs74471458 rs75187416 rs75261948 rs77669275 rs77826444 rs78294420 rs78585068 rs78764657 rs79432356 rs79824544 rs79954049 rs111768354 rs112007317 rs112161700 rs112179364 rs112449204 rs112634781 rs112645197 rs112953250 rs113039019 rs113554736 rs113655375 rs113667357 rs113716682 rs113817708 rs113903010 rs114469209 rs115106387 rs115236342 rs115451246 rs115456018 rs115486928 rs115746334 rs116222309 rs117070162 rs117726480 rs137933683 rs138105638 rs138340413 rs138550343 rs138596459 rs138675831 rs138687357 rs138782122 rs139109027 rs139200691 rs139452662 rs139541290 rs139676930 rs139714695 rs139730401 rs139921976 rs139943057 rs140161212 rs140193355 rs140355261 rs140422742 rs140581061 rs140728632 rs140752217 rs141108057 rs141333855 rs141585467 rs141607155 rs141699118 rs141749477 rs141850243 rs142296281 rs142375892 rs142425279 rs142439561 rs142966308 rs143071998 rs143158202 rs143510426 rs143682015 rs143822252 rs143966082 rs143997373 rs144203939 rs144469126 rs144627456 rs144712904 rs144721069 rs145202723 rs145330037 rs145390637 rs145416523 rs145582851 rs145664747 rs145669559 rs145748078 rs145779318 rs145788228 rs145961716 rs146230959 rs146568511 rs146754704 rs147020143 rs147111602 rs147125009 rs147712707 rs147729006 rs147736753 rs147752776 rs147901238 rs147937926 rs147972695 rs148274077 rs148316437 rs148317879 rs148446343 rs148633152 rs148711647 rs148743981 rs148793140 rs149185126 rs149271930 rs149507710 rs149827186 rs149870259 rs149879487 rs149950096 rs150187589 rs150198293 rs150588318 rs150639557 rs150881804 rs151203800 rs180700764 rs180773853 rs181210913 rs181414078 rs181425789 rs181447725 rs181454120 rs181465022 rs181468119 rs181586830 rs181612501 rs182026134 rs182034624 rs182039530 rs182068625 rs182246672 rs182271636 rs182312419 rs182399898 rs182623400 rs182639078 rs182800331 rs183089029 rs183096525 rs183506711 rs183536313 rs183755082 rs183763368 rs183768333 rs183787538 rs183793961 rs184002465 rs184095474 rs184241128 rs184309684 rs184327161 rs184335390 rs184341023 rs184469758 rs184563753 rs184904757 rs184987607 rs185000662 rs185224941 rs185242252 rs185266593 rs185694936 rs185813636 rs185997841 rs186002076 rs186012831 rs186088314 rs186138863 rs186252113 rs186388475 rs186737047 rs186829537 rs186836342 rs186996541 rs187066853 rs187071828 rs187260898 rs187531057 rs187766137 rs187785238 rs187795883 rs188303854 rs188389063 rs188472382 rs188525538 rs188546489 rs188591675 rs188640163 rs188878645 rs189039981 rs189177615 rs189283382 rs189292414 rs189401139 rs189559712 rs189924704 rs190105372 rs190120606 rs190219713 rs190354371 rs190359159 rs190639507 rs190704454 rs190760449 rs190778695 rs191136137 rs191165034 rs191209988 rs191391976 rs191706338 rs191732511 rs191940804 rs191958191 rs191967752 rs191973999 rs192213980 rs192272617 rs192313684 rs192555051 rs192783263 rs192837248 rs192867887 rs193234186 rs193263350 rs199908125 rs200901089 rs200968823 rs201027089 rs201286895 rs201431447 rs201450467 rs201645614 rs201699689 rs201821708 rs201860106 rs202074877 rs202138940 rs367576049 rs367582027 rs367590518 rs367939639 rs368005287 rs368296206 rs368465788 rs368676034 rs368725329 rs368782096 rs369031755 rs369797181 rs370065470 rs370199610 rs370438919 rs370486502 rs370486634 rs370772300 rs371018131 rs371184172 rs371360704 rs371395555 rs371565910 rs371732540 rs371893855 rs372231982 rs372351170 rs372534674 rs372741732 rs372755437 rs373014415 rs373216669 rs373326352 rs373482461 rs374028591 rs374089649 rs374218556 rs374508547 rs374584541 rs374799825 rs374814627 rs374907639 rs374926260 rs375059964 rs375932085 rs376112268 rs376124415 rs376135947 rs376204639 rs377322915 rs377530978 rs377626940 rs527485648 rs527491061 rs527555461 rs527675775 rs527748142 rs527812773 rs527906267 rs527960082 rs528029485 rs528092131 rs528464429 rs528674838 rs528678230 rs528988199 rs529015840 rs529270080 rs529470652 rs529489815 rs529586906 rs529652638 rs529714154 rs529935139 rs530166880 rs530262073 rs530422651 rs530446511 rs531000451 rs531014557 rs531117407 rs531316821 rs531380190 rs531405613 rs531531216 rs531542527 rs531543714 rs531607406 rs531665100 rs531681677 rs531943382 rs531962651 rs532159855 rs532195938 rs532272382 rs532359373 rs532474212 rs532495768 rs532499758 rs532734310 rs532975171 rs533316116 rs533356479 rs533376029 rs533521728 rs533613235 rs533745721 rs533768494 rs533818700 rs534020143 rs534192751 rs534257628 rs534538084 rs534563222 rs534748214 rs534793306 rs534892498 rs534951796 rs535078648 rs535277508 rs535289719 rs535312109 rs535322773 rs535337830 rs535620606 rs535650826 rs535900562 rs535909446 rs535936234 rs535972563 rs536122125 rs536191585 rs536498095 rs536769786 rs536774034 rs536794358 rs536845259 rs536891781 rs537091483 rs537223911 rs537314842 rs537510126 rs537653230 rs537720387 rs537722783 rs537833409 rs537886450 rs538311402 rs538420367 rs538621146 rs538632608 rs538643046 rs538669589 rs538832739 rs539023550 rs539255202 rs539260453 rs539262076 rs539322144 rs539886768 rs540337468 rs540702483 rs541087394 rs541107556 rs541189343 rs541210963 rs541281128 rs541284456 rs541438347 rs541462345 rs541742894 rs541808238 rs541869263 rs542055976 rs542068028 rs542257327 rs542545421 rs542714708 rs542840575 rs542876372 rs542971637 rs543040483 rs543230642 rs543244209 rs543351515 rs543523580 rs543623202 rs543655309 rs543774692 rs543795202 rs544057978 rs544259545 rs544276401 rs544521130 rs544682409 rs544771427 rs545223578 rs545374010 rs545432563 rs545444588 rs545508577 rs545656707 rs545670630 rs545671939 rs545698083 rs545945562 rs546107817 rs546251174 rs546282579 rs546338197 rs546403337 rs546648936 rs546768602 rs546827178 rs546986147 rs547170066 rs547184133 rs547267439 rs547406332 rs547453529 rs547487290 rs547508778 rs547656470 rs547928880 rs547996524 rs548237104 rs548405186 rs548405730 rs548684407 rs548751463 rs548838073 rs549029426 rs549142837 rs549206322 rs549276264 rs549315528 rs549452402 rs549464338 rs549721422 rs549824970 rs549828590 rs549883169 rs549892313 rs550066305 rs550113811 rs550191166 rs550236723 rs550448257 rs550740702 rs550871158 rs551122540 rs551192894 rs551314425 rs551519444 rs551808118 rs551809042 rs551832930 rs551856062 rs551903005 rs551940321 rs551995950 rs552044215 rs552062394 rs552190805 rs552450033 rs552726976 rs552863996 rs553159667 rs553188382 rs553223012 rs553262210 rs553302587 rs553415211 rs553839427 rs553915973 rs555098623 rs555194493 rs555257481 rs555258087 rs555432678 rs555446666 rs555588944 rs556220310 rs556283758 rs556503694 rs556650624 rs556767318 rs556902791 rs557149665 rs557305684 rs557563188 rs557642969 rs557652278 rs557815314 rs558124508 rs558228574 rs558278668 rs558444773 rs558501646 rs558567511 rs558760604 rs558770164 rs558834688 rs558919375 rs559163856 rs559225463 rs559268729 rs559293669 rs559377690 rs559392619 rs559410716 rs559630438 rs559686715 rs560000825 rs560057350 rs560165541 rs560192623 rs560480555 rs560750129 rs560751937 rs560812824 rs560865526 rs561002658 rs561029775 rs561084110 rs561371985 rs561436362 rs561560796 rs562109979 rs562115782 rs562271323 rs562303895 rs562382837 rs562438914 rs562452936 rs563022613 rs563044269 rs563070279 rs563160913 rs563261216 rs563425706 rs563434875 rs563493089 rs563501158 rs563563897 rs563567018 rs563604238 rs563825430 rs564051341 rs564611663 rs564724759 rs564746136 rs565026207 rs565087119 rs565087173 rs565104633 rs565165731 rs565223141 rs565580106 rs565756662 rs565838103 rs566091901 rs566294995 rs566406473 rs566801960 rs566836500 rs566838370 rs566893086 rs567089575 rs567111697 rs567222881 rs567480480 rs567495535 rs567591221 rs567630881 rs567693452 rs567974113 rs568260757 rs568282467 rs568393849 rs568478034 rs568641557 rs568667413 rs568697072 rs568731150 rs568731249 rs568779023 rs568844003 rs569046261 rs569081546 rs569189889 rs569236285 rs569494722 rs569556452 rs569634260 rs569777841 rs569818309 rs569860720 rs569875514 rs569936866 rs570051168 rs570196080 rs570573801 rs570820310 rs570844092 rs571284543 rs571353211 rs571505142 rs571616925 rs571635876 rs571744608 rs572148458 rs572201419 rs572460717 rs572627492 rs572677434 rs572876659 rs572955730 rs573030625 rs573413334 rs573576203 rs573581708 rs573604531 rs573644867 rs573691243 rs573822601 rs574227896 rs574297010 rs574371205 rs574445727 rs574567896 rs574640171 rs574892588 rs574903802 rs575189962 rs575306131 rs575372884 rs575516082 rs575568074 rs575618014 rs576026364 rs576040332 rs576358568 rs576697878 rs576779576 rs576843362 rs576981923 rs577064877 rs577094041 rs577157270 rs577296944 rs577590322 rs577699651 rs578223298 rs578257308 rs745489865 rs745626198 rs745786117 rs745797922 rs745814405 rs745882851 rs746094226 rs746102925 rs746262049 rs746394187 rs746479314 rs746635809 rs746675088 rs746684076 rs746845845 rs746880896 rs746971934 rs747101758 rs747540614 rs747800894 rs747817354 rs747859229 rs748016897 rs748023655 rs748058776 rs748217851 rs748236460 rs748261208 rs748422560 rs748566178 rs748640574 rs748703460 rs748850354 rs748873073 rs748900265 rs749095316 rs749172345 rs749380087 rs749459749 rs749476253 rs749512155 rs749611572 rs749794177 rs749810355 rs750032222 rs750108651 rs750301316 rs750376422 rs750470018 rs750555967 rs750673543 rs750735864 rs750918249 rs750958612 rs751119887 rs751246524 rs751254421 rs751370192 rs751520614 rs751763653 rs751832143 rs751951868 rs752020625 rs752037775 rs752108433 rs752211414 rs752303588 rs752394944 rs752473076 rs752756881 rs752813465 rs752986599 rs753161473 rs753163577 rs753292003 rs753325328 rs753534506 rs753799040 rs753982121 rs754123285 rs754283332 rs754284573 rs754335127 rs754353680 rs754473590 rs754645520 rs754735403 rs754735752 rs754879270 rs754927937 rs754968125 rs755118922 rs755204879 rs755222173 rs755248651 rs755288063 rs755337198 rs755577760 rs755797375 rs755800998 rs755966203 rs756077272 rs756091902 rs756109868 rs756248948 rs756357832 rs756433405 rs756662615 rs756730062 rs756795061 rs756833413 rs756998114 rs757230559 rs757281570 rs757473117 rs757821409 rs758226196 rs758385819 rs758403107 rs758665522 rs758723616 rs758735253 rs758743715 rs758999970 rs759136152 rs759214314 rs759645651 rs759938073 rs760060230 rs760083898 rs760188743 rs760254800 rs760299734 rs760635660 rs760671125 rs760686651 rs760951972 rs761096029 rs761240600 rs761247761 rs761268009 rs761291784 rs761320161 rs761435716 rs761652923 rs761828438 rs761848822 rs762004846 rs762194827 rs762258894 rs762572678 rs762660414 rs762990935 rs763047916 rs763248134 rs763345646 rs763532571 rs763590207 rs763633388 rs763680303 rs763972158 rs763982181 rs764091773 rs764141268 rs764149294 rs764161631 rs764267490 rs764384027 rs764639770 rs764711024 rs764742769 rs764869395 rs765103065 rs765248633 rs765292949 rs765293295 rs765313245 rs765569223 rs765598920 rs765739949 rs766060602 rs766272736 rs766366164 rs766473447 rs766477881 rs766618281 rs766677128 rs766836872 rs766855441 rs767052020 rs767064297 rs767125303 rs767315897 rs767370767 rs767732018 rs767736847 rs767927619 rs767982031 rs767983016 rs768000139 rs768110986 rs768306900 rs768323664 rs768380166 rs768470122 rs768478884 rs768885055 rs768910026 rs769063899 rs769363328 rs769456534 rs769473048 rs769509779 rs769629221 rs770077656 rs770129614 rs770292659 rs770509855 rs770609053 rs770705280 rs770725289 rs770953467 rs771039384 rs771106108 rs771222055 rs771235578 rs771304072 rs771309969 rs771463827 rs771694686 rs771870440 rs772100275 rs772207069 rs772296942 rs772460209 rs772477178 rs772748996 rs773108172 rs773224444 rs773227916 rs773314209 rs773371203 rs773397024 rs773434059 rs773580659 rs773595509 rs773624444 rs773703530 rs773797937 rs773937044 rs773989431 rs774082727 rs774109750 rs774168721 rs774185984 rs774262240 rs774265040 rs774586724 rs774632545 rs774680066 rs774686251 rs774766119 rs774953246 rs775020810 rs775030304 rs775072566 rs775220785 rs775328500 rs775419254 rs775619056 rs775833385 rs776078249 rs776174530 rs776345362 rs776413992 rs776743510 rs776827032 rs776921395 rs777024826 rs777127885 rs777145382 rs777211814 rs777436556 rs777614318 rs777836175 rs777964975 rs778013004 rs778202770 rs778205180 rs778270963 rs778287319 rs778368968 rs778487895 rs778536184 rs778644522 rs778973808 rs779091708 rs779102038 rs779129199 rs779224668 rs779231582 rs779398469 rs779666359 rs779683816 rs779800036 rs779806677 rs779928400 rs780010841 rs780254790 rs780449767 rs780747370 rs780816937 rs780915352 rs780943065 rs780943514 rs780995079 rs781017870 rs781318043 rs781336542 rs781398947 rs781504891 rs781624633 rs869047124

CYP3A4基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TTTGTCCTACCATAAGGGCT

59

GGATCTGTGATAGCCAGCA

59

TTTGTCCTACCATAAGGGCT

59

GATCTGTGATAGCCAGCAC

58

TTTACCCAATAAGGCACCAC

58

CTGAGCGTTTCATTCACCA

59

TTGTCCTACCATAAGGGCT

58

GATCTGTGATAGCCAGCAC

58

TACCCAATAAGGCACCACC

59

ATCTGAGCGTTTCATTCACC

59

TTACCCAATAAGGCACCAC

57

TCTGAGCGTTTCATTCACC

58

尚未收录相关数据

CYP3A4基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

CYP3A4基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0005506

C9JBD2(UniProtKB)

IEA

GO:0016705

C9JBD2(UniProtKB)

IEA

GO:0020037

C9JBD2(UniProtKB)

IEA

GO:0055114

C9JBD2(UniProtKB)

IEA

GO:0004497

E7EVM8(UniProtKB)

IEA

GO:0005506

E7EVM8(UniProtKB)

IEA

GO:0016021

E7EVM8(UniProtKB)

IEA

GO:0016705

E7EVM8(UniProtKB)

IEA

GO:0020037

E7EVM8(UniProtKB)

IEA

GO:0055114

E7EVM8(UniProtKB)

IEA

GO:0004497

P08684(UniProtKB)

ISS

GO:0004497

P08684(UniProtKB)

IDA

GO:0005496

P08684(UniProtKB)

IDA

GO:0005506

P08684(UniProtKB)

IDA

GO:0005737

P08684(UniProtKB)

IDA

GO:0005789

P08684(UniProtKB)

TAS

GO:0005789

P08684(UniProtKB)

TAS

GO:0005789

P08684(UniProtKB)

TAS

GO:0005789

P08684(UniProtKB)

TAS

GO:0006629

P08684(UniProtKB)

TAS

GO:0006706

P08684(UniProtKB)

IMP

GO:0006805

P08684(UniProtKB)

TAS

GO:0006805

P08684(UniProtKB)

TAS

GO:0008202

P08684(UniProtKB)

IMP

GO:0008209

P08684(UniProtKB)

TAS

GO:0008395

P08684(UniProtKB)

IMP

GO:0009822

P08684(UniProtKB)

IDA

GO:0016021

P08684(UniProtKB)

IEA

GO:0016098

P08684(UniProtKB)

IDA

GO:0016491

P08684(UniProtKB)

IDA

GO:0016491

P08684(UniProtKB)

IDA

GO:0016491

P08684(UniProtKB)

IDA

GO:0017144

P08684(UniProtKB)

IDA

GO:0017144

P08684(UniProtKB)

IDA

GO:0019825

P08684(UniProtKB)

TAS

GO:0019825

P08684(UniProtKB)

TAS

GO:0019825

P08684(UniProtKB)

TAS

GO:0019825

P08684(UniProtKB)

TAS

GO:0019899

P08684(UniProtKB)

IPI

GO:0020037

P08684(UniProtKB)

IEA

GO:0030343

P08684(UniProtKB)

IDA

GO:0033780

P08684(UniProtKB)

IEA

GO:0034875

P08684(UniProtKB)

IDA

GO:0036378

P08684(UniProtKB)

IEA

GO:0042359

P08684(UniProtKB)

IC

GO:0042737

P08684(UniProtKB)

IDA

GO:0042737

P08684(UniProtKB)

IMP

GO:0042738

P08684(UniProtKB)

IDA

GO:0043231

P08684(UniProtKB)

TAS

GO:0046483

P08684(UniProtKB)

IDA

GO:0047638

P08684(UniProtKB)

IEA

GO:0050591

P08684(UniProtKB)

IEA

GO:0050649

P08684(UniProtKB)

IMP

GO:0055114

P08684(UniProtKB)

IDA

GO:0055114

P08684(UniProtKB)

IDA

GO:0070330

P08684(UniProtKB)

IEA

GO:0070576

P08684(UniProtKB)

IDA

GO:0070989

P08684(UniProtKB)

IDA

GO:0070989

P08684(UniProtKB)

IDA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控CYP3A4基因的相关microRNA：

hsa-miR-27b hsa-miR-27b*

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Mammary Neoplasms	0.133635564	10	0	BeFree_CTD_human_GAD_LHGDN
Prostatic Neoplasms	0.122995792	3	0	BeFree_CTD_human_LHGDN
Osteosarcoma	0.12272435	1	0	CTD_human_LHGDN
Hepatitis C	0.120542884	3	0	BeFree_CTD_human
Torsades de Pointes	0.12	1	0	CTD_human
Diabetes Mellitus, Non-Insulin-Dependent	0.093006804	7	0	BeFree_CTD_rat_GAD_LHGDN
Kidney Failure, Chronic	0.080542884	3	0	BeFree_RGD
Anxiety Disorders	0.08	1	0	RGD
Inflammation	0.08	1	0	CTD_rat
Malignant neoplasm of prostate	0.050749832	39	0	BeFree_GAD
Malignant neoplasm of breast	0.049588119	33	2	BeFree_GAD
HIV Infections	0.029023212	21	1	BeFree_GAD
Malignant neoplasm of lung	0.015559401	10	0	BeFree_GAD
leukemia	0.010282454	7	0	BeFree_GAD
Liver diseases	0.010096888	4	0	BeFree_GAD_LHGDN
ovarian neoplasm	0.009825446	4	0	GAD_LHGDN
Acute Coronary Syndrome	0.00973957	4	0	BeFree_GAD
Hypertensive disease	0.008458305	6	5	BeFree_GAD
Hypercholesterolemia	0.008186863	7	2	BeFree_GAD
Colorectal Cancer	0.007915422	6	0	BeFree_GAD
Prostate carcinoma	0.007600372	28	0	BeFree
Malignant neoplasm of urinary bladder	0.007372538	4	0	BeFree_GAD
Neutropenia	0.007372538	4	0	BeFree_GAD
Malignant neoplasm of ovary	0.007372538	3	1	BeFree_GAD
Liver carcinoma	0.007338862	18	0	BeFree_LHGDN
Head and Neck Neoplasms	0.007101096	3	0	GAD
Laryngeal neoplasm	0.007101096	3	0	GAD
Malignant neoplasm of testis	0.007101096	3	0	GAD
Coronary Artery Disease	0.007101096	3	0	GAD
Osteoporosis	0.005634266	2	0	BeFree_GAD_LHGDN
Diabetes Mellitus	0.00554839	5	0	BeFree_GAD
Schizophrenia	0.00554839	3	0	BeFree_GAD
Lung Neoplasms	0.005362824	3	0	BeFree_GAD_LHGDN
Hyperlipidemia	0.005005506	3	0	BeFree_GAD
Colorectal Neoplasms	0.004734064	2	0	GAD
Esophageal Neoplasms	0.004734064	2	0	GAD
Mouth Neoplasms	0.004734064	2	0	GAD
Neoplasms, Germ Cell and Embryonal	0.004734064	2	0	GAD
Pharyngeal Neoplasms	0.004734064	2	0	GAD
Malignant neoplasm of liver	0.004734064	2	0	GAD
Liver Cirrhosis	0.004353001	6	0	BeFree_LHGDN
Breast Carcinoma	0.00434307	16	2	BeFree
Myopathy	0.003724241	6	0	BeFree_GAD
Precursor Cell Lymphoblastic Leukemia Lymphoma	0.003724241	5	3	BeFree_GAD
Epilepsy	0.003181358	4	0	BeFree_GAD
Carcinogenesis	0.002985861	11	1	BeFree
Diarrhea	0.002909916	3	0	BeFree_GAD
Kidney Failure, Acute	0.002909916	3	0	BeFree_GAD
Hot flushes	0.002909916	2	0	BeFree_GAD
beta Thalassemia	0.00272435	1	0	LHGDN
Endometrial Neoplasms	0.00272435	1	0	LHGDN
Thalassemia	0.00272435	1	0	LHGDN
Asthma	0.002638474	2	0	BeFree_GAD
Ulcerative Colitis	0.002638474	2	0	BeFree_GAD
Leukopenia	0.002638474	2	0	BeFree_GAD
Myocardial Infarction	0.002638474	2	0	BeFree_GAD
Neoplasm Metastasis	0.002638474	2	0	BeFree_GAD
Peripheral T-Cell Lymphoma	0.002638474	2	0	BeFree_GAD
Lingual-Facial-Buccal Dyskinesia	0.002638474	1	0	BeFree_GAD
Liver Failure, Acute	0.002638474	2	0	BeFree_GAD
Gastrointestinal Stromal Tumors	0.002638474	2	0	BeFree_GAD
Metabolic Syndrome X	0.002638474	1	0	BeFree_GAD
Tardive Dyskinesia	0.002638474	1	0	BeFree_GAD
Treatment related leukaemia	0.002638474	2	0	BeFree_GAD
Liver neoplasms	0.002442977	9	0	BeFree
Acquired Immunodeficiency Syndrome	0.002367032	1	0	GAD
Non-Small Cell Lung Carcinoma	0.002367032	1	0	GAD
Renal Cell Carcinoma	0.002367032	1	0	GAD
Squamous cell carcinoma	0.002367032	1	0	GAD
Neoplastic Cell Transformation	0.002367032	1	0	GAD
Drug Allergy	0.002367032	1	0	GAD
Exanthema	0.002367032	1	0	GAD
Femur Head Necrosis	0.002367032	1	0	GAD
Heroin Dependence	0.002367032	1	0	GAD
Hypopharyngeal Neoplasms	0.002367032	1	0	GAD
Kidney Diseases	0.002367032	1	0	GAD
Kidney Neoplasm	0.002367032	1	0	GAD
Lymphoid leukemia	0.002367032	1	0	GAD
Lupus Nephritis	0.002367032	1	0	GAD
Malaria	0.002367032	1	0	GAD
Animal Mammary Neoplasms	0.002367032	1	0	GAD
Bone necrosis	0.002367032	1	0	GAD
Skin Neoplasms	0.002367032	1	0	GAD
Testicular Neoplasms	0.002367032	1	0	GAD
Genitourinary Neoplasms	0.002367032	1	0	GAD
Lymphoma, T-Cell, Cutaneous	0.002367032	1	0	GAD
Ovarian Failure, Premature	0.002367032	1	0	GAD
Migraine Disorders	0.002367032	1	0	GAD
Malignant neoplasm of mouth	0.002367032	1	0	GAD
Squamous Cell Neoplasms	0.002367032	1	0	GAD
Dyslipidemias	0.002367032	1	0	GAD
Cervix carcinoma	0.002367032	1	0	GAD
Malignant neoplasm of esophagus	0.002367032	1	0	GAD
Thyroid carcinoma	0.002367032	1	0	GAD
Epithelial ovarian cancer	0.002367032	1	0	GAD
Helicobacter pylori infection	0.002367032	1	0	GAD
Renal Insufficiency	0.002367032	1	0	GAD
Delayed Graft Function	0.002367032	1	0	GAD
Prostatic Hyperplasia	0.002367032	1	0	GAD
MYELODYSPLASTIC SYNDROME	0.002367032	1	0	GAD
Acute lymphocytic leukemia	0.001628651	6	3	BeFree
Hyperlipoproteinemia Type III	0.001357209	5	0	BeFree
Leukemia, Myelocytic, Acute	0.001357209	5	1	BeFree
Carcinoma of lung	0.001357209	5	0	BeFree
Colon Carcinoma	0.001357209	5	0	BeFree
Benign Prostatic Hyperplasia	0.001357209	5	0	BeFree
Coronary Arteriosclerosis	0.001085767	4	0	BeFree
Coronary heart disease	0.001085767	4	0	BeFree
Cirrhosis	0.001085767	4	0	BeFree
Cholestasis	0.000814326	3	0	BeFree
Colorectal Carcinoma	0.000814326	3	0	BeFree
Myeloid Leukemia, Chronic	0.000814326	3	0	BeFree
Small cell carcinoma of lung	0.000814326	3	0	BeFree
Hepatoblastoma	0.000814326	3	0	BeFree
Absence of pain sensation	0.000814326	3	1	BeFree
Adenocarcinoma	0.000542884	2	0	BeFree
Arteriosclerosis	0.000542884	2	0	BeFree
Atherosclerosis	0.000542884	2	0	BeFree
Malignant tumor of colon	0.000542884	2	0	BeFree
Malignant neoplasm of endometrium	0.000542884	2	0	BeFree
Primary biliary cirrhosis	0.000542884	2	0	BeFree
Diabetes	0.000542884	2	0	BeFree
Nephrotic Syndrome	0.000542884	2	0	BeFree
Obesity	0.000542884	2	0	BeFree
Tuberculosis	0.000542884	2	0	BeFree
Chronic liver disease	0.000542884	2	0	BeFree
Primary hypercholesterolemia	0.000542884	2	0	BeFree
Non-alcoholic Fatty Liver Disease	0.000542884	2	0	BeFree
Endometrial Carcinoma	0.000542884	2	0	BeFree
Hepatitis C, Chronic	0.000542884	2	0	BeFree
Adenocarcinoma of large intestine	0.000542884	2	0	BeFree
Uterine Corpus Cancer	0.000542884	2	0	BeFree
LIPOPROTEIN GLOMERULOPATHY	0.000542884	2	0	BeFree
Aplastic Anemia	0.000271442	1	0	BeFree
Cooley's anemia	0.000271442	1	0	BeFree
Azoospermia	0.000271442	1	0	BeFree
Cerebral Infarction	0.000271442	1	6	BeFree
Crohn Disease	0.000271442	1	0	BeFree
Cystic Fibrosis	0.000271442	1	0	BeFree
Delirium	0.000271442	1	0	BeFree
Fatty Liver	0.000271442	1	0	BeFree
Gastroesophageal reflux disease	0.000271442	1	0	BeFree
Hepatitis B	0.000271442	1	0	BeFree
Inflammatory Bowel Diseases	0.000271442	1	0	BeFree
Leukemia, Lymphocytic, Acute, L1	0.000271442	1	0	BeFree
Lymphoma	0.000271442	1	0	BeFree
Primary malignant neoplasm of liver	0.000271442	1	0	BeFree
Mesothelioma	0.000271442	1	0	BeFree
Metabolic Diseases	0.000271442	1	2	BeFree
Neuroblastoma	0.000271442	1	0	BeFree
Ovarian Carcinoma	0.000271442	1	1	BeFree
Pain, Postoperative	0.000271442	1	0	BeFree
Peripheral Neuropathy	0.000271442	1	0	BeFree
Cerebrovascular accident	0.000271442	1	6	BeFree
Subarachnoid Hemorrhage	0.000271442	1	0	BeFree
Thromboembolism	0.000271442	1	0	BeFree
Viremia	0.000271442	1	0	BeFree
Alcohol abuse	0.000271442	1	0	BeFree
Depressive Symptoms	0.000271442	1	0	BeFree
Myocardial Ischemia	0.000271442	1	0	BeFree
Hepatic necrosis	0.000271442	1	0	BeFree
Aortic Aneurysm, Thoracic	0.000271442	1	10	BeFree
gliosarcoma	0.000271442	1	0	BeFree
Chronic schizophrenia	0.000271442	1	0	BeFree
Xanthomatosis, Cerebrotendinous	0.000271442	1	0	BeFree
Hepatitis, Autoimmune	0.000271442	1	0	BeFree
Somatotropin deficiency	0.000271442	1	0	BeFree
Adenocarcinoma of colon	0.000271442	1	0	BeFree
Osteomalacia secondary to drug	0.000271442	1	0	BeFree
Neuropathy	0.000271442	1	0	BeFree
Lower Urinary Tract Symptoms	0.000271442	1	0	BeFree
Leukemogenesis	0.000271442	1	0	BeFree
Malignant neoplasm of gastrointestinal tract	0.000271442	1	0	BeFree
Secondary malignant neoplasm of lymph node	0.000271442	1	0	BeFree
Carcinoma of bladder	0.000271442	1	0	BeFree
Central neuroblastoma	0.000271442	1	0	BeFree
21-hydroxylase deficiency	0.000271442	1	0	BeFree
Enzyme inhibition disorder	0.000271442	1	0	BeFree
Advanced cancer	0.000271442	1	0	BeFree
Diffuse panbronchiolitis	0.000271442	1	0	BeFree
Colorectal cancer metastatic	0.000271442	1	0	BeFree
Infusion related reaction	0.000271442	1	2	BeFree
Congenital long QT syndrome	0.000271442	1	0	BeFree
Sarcoma	0.000271442	1	0	BeFree
Advanced cirrhosis	0.000271442	1	0	BeFree
Hepatocarcinogenesis	0.000271442	1	0	BeFree
Transformed migraine	0.000271442	1	0	BeFree
Steatohepatitis	0.000271442	1	0	BeFree
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency	0.000271442	1	0	BeFree