CTLA4(cytotoxic T-lymphocyte-associated protein 4) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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2q33
基因染色体位置图

This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因是免疫球蛋白超家族的成员,并编码一种发送抑制性信号到T细胞的蛋白质。该蛋白质包含V结构域,跨膜结构域和胞质尾。备用转录剪接变体,编码不同同种型,已经表征。膜结合同种型用作通过二硫键相互连接的同型二聚体,而可溶性同种型用作单体。在这种基因突变已与胰岛素依赖型糖尿病,格雷夫斯病,桥本甲状腺炎,腹腔疾病,系统性红斑狼疮,甲状腺相关眼病,以及其他自身免疫性疾病相关联。 [由RefSeq的,2008年7月提供]

CTLA4基因的碱基序列:[NCBI]
CTLA4基因的碱基突变:           显示全部snp
rs231721       rs231771       rs231772       rs231773       rs231774       rs231775       rs231776       rs231777       rs231778       rs231779       rs231780       rs231781       rs733618       rs733619       rs1065442       rs3087241       rs3087242       rs3087243       rs4553808       rs5742909       rs11571315       rs11571316       rs11571317       rs11571318       rs11571319       rs11571324       rs13384548       rs13410149       rs16840252       rs16840275       rs34031880       rs34162447       rs35219727       rs35411154       rs35482731       rs35832561       rs36021810      
rs41265961       rs55657178       rs55696217       rs55806747       rs56083753       rs56102377       rs56217811       rs56387603       rs59665421       rs62182595       rs67181450       rs73993040       rs74808460       rs75339524       rs79971295       rs111771307       rs111860407       rs112472527       rs112506375       rs112640013       rs113318671       rs113505692       rs113528941       rs114352937       rs115395872       rs115552468       rs115832527       rs117492436       rs138029887       rs138160778       rs138279736       rs139105990       rs139154557       rs139354616       rs140298725       rs140690384       rs140842959       rs142975926       rs143179855       rs144795106       rs144988077       rs145606860       rs145746390       rs145950656       rs146200342       rs146541851       rs146571801       rs147267715       rs147514192       rs147679342       rs148281316       rs148575091       rs149674062       rs151127713       rs181481382       rs181723616       rs182356877       rs182533364       rs182554438       rs183868708       rs184294545       rs185654189       rs187201888       rs188456452       rs188607442       rs188823513       rs188862082       rs190067755       rs190211458       rs190363127       rs190364914       rs190838764       rs192924632       rs199912925       rs199943943       rs200180357       rs200271600       rs200657280       rs201778935       rs202187877       rs368427057       rs369073139       rs369257616       rs369567630       rs369580033       rs369757839       rs370443546       rs370681295       rs372230996       rs372830774       rs372929906       rs373219319       rs373750013       rs375949600       rs376038796       rs376126248       rs376571886       rs376591332       rs376860736       rs527537465       rs527623445       rs527697475       rs527732902       rs528140387       rs529248735       rs529921444       rs530261738       rs531208959       rs531476564       rs531518397       rs531591640       rs531665140       rs531963406       rs532076705       rs532544606       rs533622266       rs534771273       rs535151674       rs536149078       rs536508085       rs536663242       rs536709292       rs537074397       rs537388069       rs538117059       rs538455913       rs538504190       rs539459028       rs540795560       rs540826181       rs541812855       rs543350052       rs543539553       rs543604256       rs543764443       rs544593928       rs544825169       rs545750553       rs545928317       rs546153605       rs546197304       rs546283952       rs547842934       rs547979414       rs548257403       rs548781922       rs549521683       rs550124970       rs550150412       rs550168522       rs550184057       rs551032043       rs552163643       rs552409272       rs552521913       rs552832674       rs553452906       rs553848574       rs553888670       rs554636682       rs555018383       rs555383247       rs556239453       rs556435155       rs556813027       rs557116456       rs557736617       rs557863021       rs558774927       rs558812504       rs560113547       rs560235746       rs560471361       rs560892426       rs561368432       rs562266075       rs562375170       rs563844436       rs564384358       rs564531739       rs566301635       rs566707756       rs567290455       rs568556838       rs568671903       rs569353247       rs570256053       rs570935355       rs571023374       rs571127332       rs571210456       rs571773670       rs573076880       rs573163834       rs573554201       rs574061803       rs574485746       rs576174849       rs576489374       rs576571682       rs577004588       rs577641121       rs578120003       rs745731400       rs745734610       rs746318969       rs746900785       rs746944635       rs747065771       rs747155841       rs748599835       rs748802696       rs749059847       rs749973402       rs750382377       rs750841862       rs751112749       rs751528406       rs751702546       rs752037577       rs752339954       rs752433569       rs752811424       rs752988825       rs753236524       rs753717111       rs754716487       rs754725143       rs754809262       rs755030089       rs755080468       rs755615887       rs755931042       rs756092565       rs756706504       rs756791610       rs757566658       rs757773669       rs757989570       rs758079392       rs758212988       rs758465752       rs758600786       rs759232662       rs759344822       rs759766975       rs759955092       rs760167734       rs760191875       rs760446668       rs760488847       rs761135466       rs761227535       rs761319270       rs761713812       rs763030646       rs763121200       rs763343304       rs763548012       rs764001287       rs764089901       rs764639840       rs765202021       rs765325921       rs765449743       rs766143912       rs766577200       rs766875859       rs766893214       rs767100685       rs767174634       rs767352102       rs767441580       rs767995794       rs768081040       rs768137942       rs768744604       rs768961499       rs769368847       rs769380431       rs770065318       rs770198835       rs770666846       rs771072678       rs771610076       rs771695723       rs771778306       rs771987351       rs772226669       rs772433747       rs773192899       rs773279316       rs773775010       rs774080960       rs774434261       rs774909973       rs776440178       rs776726776       rs777271094       rs777277372       rs777300741       rs778114608       rs778534474       rs778678737       rs779582328       rs779775271       rs779934500       rs781579729       rs781764712      

CTLA4基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATTTCTCACAATGCACGTGG
60
TGCCTGGAGATGCATACTC
59
GGCTTGCCTTGGATTTCAG
60
TTAGCTTTGCAGAAGACAGG
58
CTTGCCTTGGATTTCAGCG
60
TTTAGCTTTGCAGAAGACAGG
59
CTTGCCTTGGATTTCAGCG
60
TTAGCTTTGCAGAAGACAGG
58
TCTTCTGCAAAGCAATGCA
59
CTGGAGATGCATACTCACAC
58
CTTCTGCAAAGCAATGCAC
59
CTGGAGATGCATACTCACAC
58
TCTTCATCCCTGTCTTCTGC
60
TTTCTTTAGACACAAAGCTGGC
60
CTATTTCTCACAATGCACGTG
58
CCTGGAGATGCATACTCAC
57
CTTCATCCCTGTCTTCTGCA
60
CACATTCTGGCTCTGTTGG
59
TTCATCCCTGTCTTCTGCA
59
CACATTCTGGCTCTGTTGG
59
      尚未收录相关数据

CTLA4基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CTLA4基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0006955
A0A0C4DH58(UniProtKB)
IEA
GO:0016020
A0A0C4DH58(UniProtKB)
IEA
GO:0002250
P16410(UniProtKB)
IEA
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005515
P16410(UniProtKB)
IPI
GO:0005794
P16410(UniProtKB)
IDA
GO:0005886
P16410(UniProtKB)
TAS
GO:0005886
P16410(UniProtKB)
TAS
GO:0005886
P16410(UniProtKB)
TAS
GO:0005886
P16410(UniProtKB)
TAS
GO:0005887
P16410(UniProtKB)
TAS
GO:0006955
P16410(UniProtKB)
TAS
GO:0006974
P16410(UniProtKB)
IMP
GO:0009897
P16410(UniProtKB)
IDA
GO:0030889
P16410(UniProtKB)
IMP
GO:0031295
P16410(UniProtKB)
TAS
GO:0043065
P16410(UniProtKB)
IMP
GO:0045334
P16410(UniProtKB)
IDA
GO:0045590
P16410(UniProtKB)
IDA
GO:0048471
P16410(UniProtKB)
IDA
GO:0050853
P16410(UniProtKB)
IMP
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控CTLA4基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Rheumatoid Arthritis 0.345272224 82 9 BeFree_CTD_human_GAD_GWASCAT_LHGDN
Diabetes Mellitus, Insulin-Dependent 0.247813496 157 6 BeFree_GAD_GWASCAT_LHGDN
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME, TYPE V 0.24 1 0 ORPHANET_UNIPROT
Graves Disease 0.228259749 85 5 BeFree_CTD_human_GAD_LHGDN
Celiac Disease 0.174546137 34 0 BeFree_CTD_human_GAD_LHGDN
Hashimoto Disease 0.149181152 11 2 BeFree_CTD_human_GAD_LHGDN
melanoma 0.136892866 19 0 BeFree_CTD_human_GAD_LHGDN
Graft-vs-Host Disease 0.130553895 9 0 BeFree_CTD_human_GAD
Juvenile arthritis 0.12554839 5 0 BeFree_CTD_human_GAD
Oral Submucous Fibrosis 0.122638474 2 0 BeFree_CTD_human_GAD
Alopecia Areata 0.122367032 1 0 CTD_human_GAD
Lymphoma, T-Cell, Cutaneous 0.120542884 3 0 BeFree_CTD_human
Peripheral Neuropathy 0.120271442 1 0 BeFree_CTD_human
Adult T-Cell Lymphoma/Leukemia 0.12 1 0 CTD_human
DIABETES MELLITUS, INSULIN-DEPENDENT, 12 0.12 0 0 CTD_human
CELIAC DISEASE, SUSCEPTIBILITY TO, 3 (finding) 0.12 0 1 CLINVAR
Myocarditis 0.082995792 2 0 BeFree_LHGDN_RGD
Arthritis, Experimental 0.080271442 1 0 BeFree_RGD
Lupus Erythematosus, Systemic 0.067790707 59 4 BeFree_GAD_LHGDN
Autoimmune Diseases 0.063853648 143 7 BeFree_GAD_LHGDN
Multiple Sclerosis 0.063633202 43 0 BeFree_GAD_LHGDN
Asthma 0.038196154 25 9 BeFree_GAD_LHGDN
Ulcerative Colitis 0.031204679 16 1 BeFree_GAD_LHGDN
Myasthenia Gravis 0.028542461 17 0 BeFree_GAD_LHGDN
Systemic Scleroderma 0.024989972 8 3 BeFree_GAD_LHGDN
Lupus Erythematosus 0.023474823 16 0 BeFree_GAD
Thyroid associated opthalmopathies 0.022007993 13 1 BeFree_GAD_LHGDN
Diabetes Mellitus, Non-Insulin-Dependent 0.020836349 12 0 BeFree_GAD
Thyroid Diseases 0.020255908 13 0 BeFree_GAD_LHGDN
Biliary cirrhosis 0.019293574 7 0 GAD_LHGDN
Behcet Syndrome 0.019012201 11 1 BeFree_GAD
HIV Infections 0.018316089 42 0 BeFree_GAD_LHGDN
Autoimmune thyroiditis 0.017197984 7 0 BeFree_GAD_LHGDN
Inflammation 0.016569224 7 0 GAD
Autoimmune thyroid disease 0.01633012 34 5 BeFree_GAD
Vitiligo 0.015373836 6 0 BeFree_GAD_LHGDN
Crohn Disease 0.014635455 12 1 BeFree_GAD_LHGDN
Infection 0.012907115 5 0 GAD_LHGDN
Hepatitis C 0.012649486 7 0 BeFree_GAD
Granulomatosis with polyangiitis 0.012192478 4 0 GAD_LHGDN
Hepatitis, Autoimmune 0.011911105 11 0 BeFree_GAD
Hypothyroidism 0.010725648 5 1 BeFree_GAD_LHGDN
Psoriasis 0.010639772 4 0 BeFree_GAD_LHGDN
Lymphoma 0.010358398 14 0 BeFree_GAD
Cervix carcinoma 0.010358398 12 1 BeFree_GAD
Hemophilia A 0.010011012 5 0 BeFree_GAD
Hepatitis B 0.009815515 13 0 BeFree_GAD
Malignant neoplasm of breast 0.009001189 7 1 BeFree_GAD
Inflammatory Bowel Diseases 0.009001189 7 1 BeFree_GAD
Neoplasm Metastasis 0.008815624 8 0 BeFree_GAD_LHGDN
Colorectal Cancer 0.008729747 7 0 BeFree_GAD
Hepatitis B, Chronic 0.008458305 6 0 BeFree_GAD
Diabetes Mellitus 0.008338753 22 0 BeFree_GAD
Squamous cell carcinoma 0.008001298 4 0 BeFree_GAD_LHGDN
Lymphoma, Non-Hodgkin 0.008001298 4 0 BeFree_GAD_LHGDN
Liver Cirrhosis, Alcoholic 0.007458414 2 0 GAD_LHGDN
Multiple Myeloma 0.007448483 11 0 BeFree_GAD
Addison Disease 0.007101096 3 0 GAD
Pancreatitis, Chronic 0.007101096 3 0 GAD
Chronic ulcerative colitis 0.007101096 3 0 GAD
Lupus Erythematosus, Discoid 0.006905599 10 0 BeFree_GAD
Dermatitis, Atopic 0.006720033 7 0 BeFree_GAD_LHGDN
Lupus Vulgaris 0.006634157 9 0 BeFree_GAD
Hypothyroidism, Autoimmune 0.006362715 7 0 BeFree_GAD
Common Variable Immunodeficiency 0.006167218 14 0 BeFree_GAD
Hepatitis C, Chronic 0.005905708 4 0 BeFree_GAD_LHGDN
Schizophrenia 0.005819831 4 0 BeFree_GAD
Ankylosing spondylitis 0.005819831 4 0 BeFree_GAD
Autoimmune hemolytic anemia 0.005720142 2 0 BeFree_LHGDN
Arthritis 0.00554839 5 0 BeFree_GAD
Uveomeningoencephalitic Syndrome 0.005362824 1 0 BeFree_GAD_LHGDN
Mammary Neoplasms 0.005362824 3 0 BeFree_GAD_LHGDN
Bronchial Hyperreactivity 0.005276948 3 1 BeFree_GAD
Malignant neoplasm of lung 0.005276948 3 0 BeFree_GAD
Colonic Neoplasms 0.005091382 1 0 GAD_LHGDN
Alcoholic Liver Diseases 0.005091382 2 0 GAD_LHGDN
Renal Cell Carcinoma 0.005005506 2 0 BeFree_GAD
Pemphigus 0.005005506 3 0 BeFree_GAD
Immune thrombocytopenic purpura 0.005005506 2 0 BeFree_GAD
Liver carcinoma 0.005005506 3 0 BeFree_GAD
Primary biliary cirrhosis 0.004885954 18 0 BeFree
Diabetes 0.004885954 18 0 BeFree
Uterine Cervical Neoplasm 0.004734064 2 0 GAD
Hay fever 0.004734064 2 0 GAD
Immediate hypersensitivity 0.004734064 2 0 GAD
Kidney Neoplasm 0.004734064 2 0 GAD
Liver diseases 0.004734064 2 0 GAD
Liver neoplasms 0.004734064 2 0 GAD
Pre-Eclampsia 0.004734064 2 0 GAD
Sarcoidosis 0.004734064 2 0 GAD
Premature Birth 0.004734064 2 0 GAD
Sjogren's Syndrome 0.004734064 2 0 GAD
Thymoma 0.004624443 7 3 BeFree_LHGDN
Chronic Lymphocytic Leukemia 0.003995683 6 0 BeFree_GAD
Periodontitis 0.003810118 4 0 BeFree_LHGDN
Endocrine System Diseases 0.003452799 4 0 BeFree_GAD
Chronic Obstructive Airway Disease 0.003452799 5 0 BeFree_GAD
Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis 0.003452799 4 0 BeFree_GAD
Bipolar Disorder 0.003267234 2 0 BeFree_LHGDN
Mycosis Fungoides 0.003267234 2 0 BeFree_LHGDN
Malignant tumor of cervix 0.003257302 12 1 BeFree
Malignant neoplasm of stomach 0.003181358 3 0 BeFree_GAD
Vasculitis 0.003181358 4 0 BeFree_GAD
Adenocarcinoma 0.002995792 2 0 BeFree_LHGDN
Glomerulonephritis 0.002995792 2 0 BeFree_LHGDN
Thyroiditis 0.002985861 11 1 BeFree
Metastatic melanoma 0.002985861 11 0 BeFree
Lymphoproliferative Disorders 0.002909916 3 0 BeFree_GAD
Myocardial Infarction 0.002909916 3 0 BeFree_GAD
Henoch-Schoenlein Purpura 0.002909916 2 0 BeFree_GAD
Tuberculosis, Pulmonary 0.002909916 2 0 BeFree_GAD
Postpartum Thyroiditis 0.002909916 2 0 BeFree_GAD
Cervical Squamous Cell Carcinoma 0.002909916 2 0 BeFree_GAD
Spondylarthropathies 0.002909916 3 0 BeFree_GAD
Precursor Cell Lymphoblastic Leukemia Lymphoma 0.002909916 3 0 BeFree_GAD
Bronchiolitis 0.00272435 1 0 LHGDN
Colorectal Neoplasms 0.00272435 1 0 LHGDN
pathologic fistula 0.00272435 1 0 LHGDN
Iridocyclitis 0.00272435 1 0 LHGDN
Lymphoid leukemia 0.00272435 1 0 LHGDN
Pancreatitis 0.00272435 1 0 LHGDN
Prostatic Neoplasms 0.00272435 1 0 LHGDN
Purpura 0.00272435 1 0 LHGDN
Mucosa-Associated Lymphoid Tissue Lymphoma 0.00272435 1 0 LHGDN
Multiple Sclerosis, Chronic Progressive 0.00272435 1 0 LHGDN
Thrombocytopenic purpura 0.00272435 1 0 LHGDN
Anemia 0.002638474 2 0 BeFree_GAD
Malignant neoplasm of urinary bladder 0.002638474 2 0 BeFree_GAD
Cardiomyopathy, Dilated 0.002638474 1 0 BeFree_GAD
Chlamydia Infections 0.002638474 2 0 BeFree_GAD
Cholangitis, Sclerosing 0.002638474 2 0 BeFree_GAD
Bronchitis, Chronic 0.002638474 1 0 BeFree_GAD
Dengue Fever 0.002638474 2 0 BeFree_GAD
Erythema Nodosum 0.002638474 2 0 BeFree_GAD
Severe Dengue 0.002638474 1 0 BeFree_GAD
Lymphohistiocytosis, Hemophagocytic 0.002638474 1 0 BeFree_GAD
Pretibial myxedema 0.002638474 1 0 BeFree_GAD
Dermatologic disorders 0.002638474 2 0 BeFree_GAD
Cerebrovascular accident 0.002638474 2 0 BeFree_GAD
Chagas Disease 0.002638474 2 0 BeFree_GAD
Uveitis, Intermediate 0.002638474 1 0 BeFree_GAD
Immunoglobulin A deficiency (disorder) 0.002638474 1 0 BeFree_GAD
Prediabetes syndrome 0.002638474 2 0 BeFree_GAD
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating 0.002638474 2 0 BeFree_GAD
Coronary Artery Disease 0.002638474 2 0 BeFree_GAD
Non-Small Cell Lung Carcinoma 0.002442977 9 0 BeFree
Virus Diseases 0.002442977 9 0 BeFree
Spontaneous abortion 0.002367032 1 0 GAD
Abruptio Placentae 0.002367032 1 0 GAD
Arthritis, Psoriatic 0.002367032 1 0 GAD
Autoimmune Response 0.002367032 1 0 GAD
Bronchiolitis, Viral 0.002367032 1 0 GAD
Calcinosis 0.002367032 1 0 GAD
Basal cell carcinoma 0.002367032 1 0 GAD
Brain Ischemia 0.002367032 1 0 GAD
Choriocarcinoma 0.002367032 1 0 GAD
Connective Tissue Diseases 0.002367032 1 0 GAD
Eosinophilia 0.002367032 1 0 GAD
Fatty Liver 0.002367032 1 0 GAD
Fetal Diseases 0.002367032 1 0 GAD
Heart Diseases 0.002367032 1 0 GAD
Hepatitis, Chronic 0.002367032 1 0 GAD
Hydatidiform Mole 0.002367032 1 0 GAD
Hypoparathyroidism 0.002367032 1 0 GAD
Leishmaniasis, Cutaneous 0.002367032 1 0 GAD
Myeloid Leukemia 0.002367032 1 0 GAD
Lymphocytosis 0.002367032 1 0 GAD
Animal Mammary Neoplasms 0.002367032 1 0 GAD
Meniere Disease 0.002367032 1 0 GAD
Musculoskeletal Diseases 0.002367032 1 0 GAD
Pregnancy Complications, Hematologic 0.002367032 1 0 GAD
Proteinuria 0.002367032 1 0 GAD
Respiratory Syncytial Virus Infections 0.002367032 1 0 GAD
Rhinitis 0.002367032 1 0 GAD
Rhinitis, Allergic, Perennial 0.002367032 1 0 GAD
Skin Neoplasms 0.002367032 1 0 GAD
Aphthous Stomatitis 0.002367032 1 0 GAD
Subacute Sclerosing Panencephalitis 0.002367032 1 0 GAD
Sunburn 0.002367032 1 0 GAD
Trachoma 0.002367032 1 0 GAD
Anterior uveitis 0.002367032 1 0 GAD
Diffuse Large B-Cell Lymphoma 0.002367032 1 0 GAD
Polyendocrinopathies, Autoimmune 0.002367032 1 0 GAD
Atopy 0.002367032 1 0 GAD
Dermatitis and eczema 0.002367032 1 0 GAD
Cardiomyopathies 0.002367032 1 0 GAD
Cardiomyopathy, Familial Idiopathic 0.002367032 1 0 GAD
Venous Thromboembolism 0.002367032 1 0 GAD
Proteinuria Adverse Event 0.002367032 1 0 GAD
Solar Erythema 0.002367032 1 0 GAD
Thyroid associated orbitopathy 0.002367032 1 0 GAD
Disorder of eye 0.002171535 8 1 BeFree
Tumor Immunity 0.002171535 8 0 BeFree
Diabetes, Autoimmune 0.001900093 7 0 BeFree
Breast Carcinoma 0.001900093 7 1 BeFree
Acute GVH disease 0.001900093 7 1 BeFree
Eczema 0.001628651 6 0 BeFree
Osteosarcoma 0.001628651 6 4 BeFree
Allergic asthma 0.001628651 6 0 BeFree
Colorectal Carcinoma 0.001357209 5 0 BeFree
Immune System Diseases 0.001357209 5 0 BeFree
Influenza 0.001357209 5 0 BeFree
Osteosarcoma of bone 0.001357209 5 4 BeFree
Allergic disposition 0.001357209 5 1 BeFree
Leukemia, Myelocytic, Acute 0.001085767 4 0 BeFree
Tumor Progression 0.001085767 4 0 BeFree
Granulomatosis 0.001085767 4 0 BeFree
Sporadic Breast Carcinoma 0.001085767 4 0 BeFree
Arteriosclerosis 0.000814326 3 0 BeFree
Atherosclerosis 0.000814326 3 0 BeFree
Kidney Failure, Chronic 0.000814326 3 0 BeFree
leukemia 0.000814326 3 0 BeFree
Acute lymphocytic leukemia 0.000814326 3 0 BeFree
Lung Neoplasms 0.000814326 3 0 BeFree
Wiskott-Aldrich Syndrome 0.000814326 3 0 BeFree
Severe Combined Immunodeficiency 0.000814326 3 0 BeFree
Polymyositis 0.000814326 3 0 BeFree
Stable angina 0.000814326 3 0 BeFree
Stomach Carcinoma 0.000814326 3 0 BeFree
cancer regression 0.000814326 3 0 BeFree
Generalized vitiligo 0.000814326 3 7 BeFree
IMMUNE SUPPRESSION 0.000814326 3 0 BeFree
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) 0.000814326 3 0 BeFree
Juvenile rheumatoid arthritis 0.000814326 3 0 BeFree
Colitis 0.000542884 2 0 BeFree
Coronary Arteriosclerosis 0.000542884 2 0 BeFree
Coronary heart disease 0.000542884 2 0 BeFree
Cytomegalovirus Infections 0.000542884 2 1 BeFree
Gingival Diseases 0.000542884 2 0 BeFree
Hyperthyroidism 0.000542884 2 0 BeFree
Immunologic Deficiency Syndromes 0.000542884 2 0 BeFree
Leprosy 0.000542884 2 0 BeFree
Lupus Erythematosus, Subacute Cutaneous 0.000542884 2 0 BeFree
Lymphopenia 0.000542884 2 0 BeFree
Mitral Valve Stenosis 0.000542884 2 0 BeFree
Monoclonal Gammopathy of Undetermined Significance 0.000542884 2 0 BeFree
Paracoccidioidomycosis 0.000542884 2 0 BeFree
Periodontal Diseases 0.000542884 2 0 BeFree
Periodontitis, Juvenile 0.000542884 2 2 BeFree
Post-kala-azar dermal leishmaniasis 0.000542884 2 0 BeFree
Tetanus 0.000542884 2 0 BeFree
Thalassemia 0.000542884 2 0 BeFree
Wheezing 0.000542884 2 6 BeFree
B-Cell Lymphomas 0.000542884 2 0 BeFree
Lymphoma, Large-Cell, Follicular 0.000542884 2 0 BeFree
Secondary malignant neoplasm of lung 0.000542884 2 0 BeFree
Pancreatic carcinoma 0.000542884 2 0 BeFree
Neoplasm, Residual 0.000542884 2 0 BeFree
Pemphigus Foliaceus 0.000542884 2 0 BeFree
Psoriasis vulgaris 0.000542884 2 0 BeFree
Chronic Periodontitis 0.000542884 2 0 BeFree
Severe hereditary factor VIII deficiency disease 0.000542884 2 0 BeFree
Malignant neoplasm of pancreas 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Primary sclerosing cholangitis 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Carcinoma of lung 0.000542884 2 0 BeFree
Carcinoma of bladder 0.000542884 2 0 BeFree
Hyperlipoproteinemia Type IIa 0.000542884 2 0 BeFree
Chronic graft-versus-host disease 0.000542884 2 0 BeFree
Acute Coronary Syndrome 0.000542884 2 0 BeFree
Arthritis, Collagen-Induced 0.000542884 2 0 BeFree
Diffuse Scleroderma 0.000542884 2 0 BeFree
Chronic kidney disease stage 5 0.000542884 2 0 BeFree
Affective Symptoms 0.000271442 1 0 BeFree
Angina, Unstable 0.000271442 1 0 BeFree
Antibody Deficiency Syndrome 0.000271442 1 0 BeFree
Arthritis, Adjuvant-Induced 0.000271442 1 0 BeFree
Melanoma, B16 0.000271442 1 0 BeFree
Bacterial Infections 0.000271442 1 0 BeFree
Mental disorders 0.000271442 1 0 BeFree
Bone neoplasms 0.000271442 1 0 BeFree
Malignant neoplasm of skin 0.000271442 1 0 BeFree
Noninfiltrating Intraductal Carcinoma 0.000271442 1 0 BeFree
Chediak-Higashi Syndrome 0.000271442 1 0 BeFree
Cholestasis 0.000271442 1 0 BeFree
Common Cold 0.000271442 1 0 BeFree
Exfoliative dermatitis 0.000271442 1 0 BeFree
Dermatomyositis 0.000271442 1 0 BeFree
Scleroderma 0.000271442 1 0 BeFree
Diabetic Ketoacidosis 0.000271442 1 0 BeFree
Experimental Autoimmune Encephalomyelitis 0.000271442 1 0 BeFree
Endometriosis 0.000271442 1 0 BeFree
Fuchs' heterochromic cyclitis 0.000271442 1 0 BeFree
Membranous glomerulonephritis 0.000271442 1 0 BeFree
Hematological Disease 0.000271442 1 0 BeFree
Hepatitis 0.000271442 1 0 BeFree
Hepatitis A 0.000271442 1 0 BeFree
Histiocytosis, Langerhans-Cell 0.000271442 1 0 BeFree
Hyperglycemia 0.000271442 1 0 BeFree
Arthropathy 0.000271442 1 0 BeFree
Kidney Diseases 0.000271442 1 0 BeFree
Leprosy, Lepromatous 0.000271442 1 0 BeFree
Leukemia, Myelomonocytic, Chronic 0.000271442 1 0 BeFree
Liver Cirrhosis 0.000271442 1 0 BeFree
Lown-Ganong-Levine Syndrome 0.000271442 1 0 BeFree
Lyme Disease 0.000271442 1 0 BeFree
Lymphocytic Choriomeningitis 0.000271442 1 0 BeFree
Lymphoma, Follicular 0.000271442 1 0 BeFree
Mucocutaneous Lymph Node Syndrome 0.000271442 1 1 BeFree
Mycoses 0.000271442 1 0 BeFree
Nephritis 0.000271442 1 0 BeFree
Lipoid nephrosis 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Papilloma 0.000271442 1 0 BeFree
Pneumonia 0.000271442 1 0 BeFree
Pulmonary Fibrosis 0.000271442 1 0 BeFree
Kidney Failure 0.000271442 1 0 BeFree
Sialadenitis 0.000271442 1 0 BeFree
Urticaria 0.000271442 1 0 BeFree
T-Cell Lymphoma 0.000271442 1 0 BeFree
Polyglandular Type I Autoimmune Syndrome 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 0 BeFree
Primary Sj�gren's syndrome 0.000271442 1 0 BeFree
Non-arthropod borne lymphocytic choriomeningitis 0.000271442 1 0 BeFree
Acute myocardial infarction 0.000271442 1 0 BeFree
Acute intermittent porphyria 0.000271442 1 0 BeFree
Aortic Aneurysm, Abdominal 0.000271442 1 0 BeFree
Malignant ascites 0.000271442 1 0 BeFree
Adult type dermatomyositis 0.000271442 1 0 BeFree
Lesion of brain 0.000271442 1 0 BeFree
Rheumatoid Vasculitis 0.000271442 1 0 BeFree
Erectile dysfunction 0.000271442 1 0 BeFree
Lyme Arthritis 0.000271442 1 0 BeFree
Age related macular degeneration 0.000271442 1 0 BeFree
Chronic urticaria 0.000271442 1 0 BeFree
Childhood asthma 0.000271442 1 0 BeFree
Axonal neuropathy 0.000271442 1 0 BeFree
Inflammatory neuropathy 0.000271442 1 0 BeFree
Pulmonary paracoccidioidomycosis 0.000271442 1 0 BeFree
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 0.000271442 1 0 BeFree
Ulcerative jejunitis 0.000271442 1 0 BeFree
Microscopic Polyangiitis 0.000271442 1 0 BeFree
Asymptomatic human immunodeficiency virus infection 0.000271442 1 0 BeFree
Chronic Chagas' disease 0.000271442 1 0 BeFree
Hereditary hemochromatosis 0.000271442 1 0 BeFree
Primary immune deficiency disorder 0.000271442 1 0 BeFree
Idiopathic crescentic glomerulonephritis 0.000271442 1 0 BeFree
Chronic rejection of renal transplant 0.000271442 1 0 BeFree
Aortic valve calcification 0.000271442 1 0 BeFree
Neuropathy 0.000271442 1 0 BeFree
Nephrotic range proteinuria 0.000271442 1 0 BeFree
Chlamydia trachomatis infection 0.000271442 1 0 BeFree
Metabolic Syndrome X 0.000271442 1 4 BeFree
Aqueous Humor Disorders 0.000271442 1 0 BeFree
Inherited neuropathies 0.000271442 1 0 BeFree
Leukemogenesis 0.000271442 1 0 BeFree
multiple pathologies 0.000271442 1 0 BeFree
Skin carcinoma 0.000271442 1 0 BeFree
early pregnancy 0.000271442 1 0 BeFree
Blood autoimmune disorders 0.000271442 1 0 BeFree
Progressive multiple sclerosis 0.000271442 1 0 BeFree
Invasive Ductal Breast Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Deficiency of vitamin D3 0.000271442 1 0 BeFree
Inflammatory disorder 0.000271442 1 0 BeFree
Precursor B-cell lymphoblastic leukemia 0.000271442 1 0 BeFree
Adenoma of large intestine 0.000271442 1 0 BeFree
Stage IV Skin Melanoma 0.000271442 1 0 BeFree
Autoimmune Lymphoproliferative Syndrome 0.000271442 1 0 BeFree
Gastric Mucosa-Associated Lymphoid Tissue Lymphoma 0.000271442 1 0 BeFree
Pancreatic Ductal Adenocarcinoma 0.000271442 1 0 BeFree
Human T-cell lymphotropic virus 1 infection 0.000271442 1 0 BeFree
Salivary Gland Pleomorphic Adenoma 0.000271442 1 0 BeFree
Glomerulonephritis, Minimal Change 0.000271442 1 0 BeFree
Bone Sarcoma 0.000271442 1 0 BeFree
Non-Neoplastic Disorder 0.000271442 1 0 BeFree
MULTICYSTIC RENAL DYSPLASIA, BILATERAL 0.000271442 1 0 BeFree
Latent autoimmune diabetes mellitus in adult 0.000271442 1 0 BeFree
Vasculitic neuropathy 0.000271442 1 0 BeFree
CD40 Ligand Deficiency 0.000271442 1 0 BeFree
Allergic rhinitis (disorder) 0.000271442 1 0 BeFree
Autoimmune pancreatitis 0.000271442 1 0 BeFree
Allergic sensitization 0.000271442 1 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000271442 1 0 BeFree
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