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The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  半胱氨酸蛋白酶抑制剂家族包括含有多种蛋白酶抑制剂类序列的蛋白质。一些成员是活性半胱氨酸蛋白酶抑制剂,而另一些人已经失去或也许从未获得这种抑制活性。有三个抑制家庭的家族,包括1型半胱氨酸蛋白酶抑制剂(stefins),2型半胱氨酸蛋白酶抑制剂和激肽原。 2型胱抑素蛋白是一类在多种人类流体和分泌物中发现的半胱氨酸蛋白酶抑制剂。该基因编码具有免疫调节,通过抑制一个唯一的目标,在造血系统中的推定作用糖化半胱氨酸蛋白酶抑制剂。在恶性肿瘤设立了各种人癌细胞系已被观察到的蛋白质的表达。 [由RefSeq的,2008年7月提供]
CST7基因(以及对应的蛋白质)的细胞分布位置:
CST7基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Stomach Neoplasms | 0.12 | 1 | 0 | CTD_human |
Diabetes Mellitus | 0.000271442 | 1 | 0 | BeFree |
Myotonia Congenita | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
Slow channel syndrome | 0.000271442 | 1 | 0 | BeFree |
Secondary malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Generalized Myotonia of Thomsen | 0.000271442 | 1 | 0 | BeFree |
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