CST1(cystatin SN)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

20p11.2
基因染色体位置图

基因简述

基因简述

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a cysteine proteinase inhibitor found in saliva, tears, urine, and seminal fluid. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  半胱氨酸蛋白酶抑制剂家族包括含有多种蛋白酶抑制剂类序列的蛋白质。一些成员是活性半胱氨酸蛋白酶抑制剂，而另一些人已经失去或也许从未获得这种抑制活性。有三个抑制家庭的家族，包括1型半胱氨酸蛋白酶抑制剂（stefins），2型半胱氨酸蛋白酶抑制剂和激肽原。 2型胱抑素蛋白是一类在多种人类流体和分泌物，它们出现，以提供保护功能的发现半胱氨酸蛋白酶抑制剂。在20号染色体的基因胱包含了大多数2型半胱氨酸蛋白酶抑制剂基因和假的。该基因位于胱抑素基因，编码在唾液中的半胱氨酸蛋白酶抑制剂，泪液，尿液和精液。 [由RefSeq的，2008年7月提供]

OMIM数据库中对CST1基因的介绍     Wikipedia数据库中对CST1基因的介绍

基因序列

基因序列

CST1基因的碱基序列：[NCBI]

基因突变

基因突变

CST1基因的碱基突变：           显示全部snp
rs2982       rs1048314       rs2070855       rs2070856       rs3188296       rs3188297       rs3188301       rs3188303       rs3188305       rs3188307       rs3188313       rs3188314       rs3188319       rs3188320       rs3188322       rs3892306       rs4260306       rs4268993       rs4300905       rs4331584       rs4332996       rs4343536       rs4416286       rs4422222       rs4465840       rs4477985       rs4488738       rs4491793       rs4505598       rs4513357       rs4528835       rs4544516       rs4549181       rs4990306       rs5841003       rs6036516       rs6049067      
rs6049070       rs6049072       rs6076122       rs6076123       rs6083249       rs6083250       rs6114254       rs6114255       rs6114256       rs6114257       rs7265165       rs7273134       rs7354713       rs11471975       rs11699215       rs11905835       rs11907329       rs13036427       rs13036683       rs13045477       rs13045804       rs35871658       rs66752417       rs71267465       rs71267466       rs71333777       rs73328966       rs73902166       rs73902167       rs74344468       rs77070731       rs77188058       rs78565162       rs80263900       rs80326245       rs111288315       rs111291244       rs111447595       rs111801460       rs111818589       rs111970344       rs112075891       rs112232806       rs112974717       rs113409795       rs113478826       rs113569021       rs113896553       rs114338481       rs114494458       rs115664080       rs115674723       rs116626492       rs117082322       rs117238940       rs117567509       rs117743070       rs117791248       rs137869967       rs137889401       rs138086767       rs139240857       rs139572277       rs139812159       rs140613927       rs140676884       rs140717036       rs140899439       rs141195433       rs141453374       rs141614535       rs141813234       rs142226596       rs142304052       rs142422717       rs142475489       rs142792460       rs143142026       rs143744155       rs143815991       rs143819315       rs144543419       rs144671606       rs144729819       rs144894955       rs145145463       rs145278724       rs146007173       rs146482789       rs146601403       rs146690838       rs146842202       rs147207882       rs148178833       rs148656170       rs149310223       rs149367943       rs149738736       rs149946437       rs150526241       rs150586879       rs150764093       rs150779373       rs151261857       rs151291851       rs180717770       rs181188860       rs181343208       rs181452131       rs181906092       rs182210543       rs182614032       rs183181008       rs183195751       rs183935304       rs184019338       rs184501011       rs184509151       rs185576939       rs185589059       rs186093495       rs186237695       rs186636982       rs187247414       rs187337179       rs187452860       rs187564181       rs187680281       rs187839806       rs188356246       rs189016076       rs189239828       rs189644912       rs190417182       rs190538900       rs190808226       rs190915622       rs191048118       rs191935285       rs192103753       rs193042297       rs193132000       rs199700673       rs199755221       rs199758963       rs200230343       rs200297144       rs200307238       rs200524765       rs200996939       rs201315915       rs201376709       rs201505177       rs201801623       rs201877331       rs367602743       rs368058887       rs368203290       rs368289519       rs368544643       rs368695583       rs370189313       rs370560948       rs370802976       rs370907239       rs372089600       rs372192719       rs372305022       rs372538698       rs372641078       rs372905911       rs373048667       rs373118474       rs373497801       rs373670958       rs373733417       rs374004963       rs374449510       rs374507475       rs374536512       rs375466801       rs375784027       rs375902412       rs375967648       rs376106415       rs376276906       rs376304783       rs376453689       rs376913437       rs376987841       rs377096439       rs527239954       rs527954599       rs528412528       rs528575607       rs528650630       rs529213045       rs529641223       rs529847679       rs529861770       rs529993400       rs530054814       rs530782485       rs531019169       rs531182531       rs531291345       rs531311199       rs532326131       rs532722807       rs533428632       rs533490229       rs533911737       rs534033005       rs534085799       rs534095026       rs534368202       rs534420407       rs534480246       rs534585539       rs534985671       rs535554326       rs535956961       rs536004069       rs536823882       rs537648836       rs538131226       rs538154101       rs538468240       rs539336692       rs539742383       rs540320613       rs540351057       rs540376777       rs540466158       rs540715655       rs540721922       rs541127496       rs542225167       rs542677936       rs542879965       rs543050637       rs543111958       rs543309720       rs543969659       rs544167220       rs544382052       rs544443313       rs544683068       rs544865924       rs544999263       rs545539848       rs545540933       rs545652181       rs545828274       rs545939931       rs546054650       rs546129523       rs546397264       rs546662529       rs546676989       rs547705648       rs548489380       rs548555858       rs548823200       rs549107471       rs549278567       rs549404430       rs549584815       rs549876122       rs550061922       rs550064441       rs550375981       rs550528965       rs550605669       rs550842222       rs551859363       rs552250628       rs552916412       rs552987091       rs553672708       rs553723881       rs553989967       rs554082880       rs554602226       rs554843443       rs555186339       rs555199581       rs555331236       rs555458200       rs555598905       rs556178746       rs556450851       rs556512299       rs556558381       rs556580964       rs556724843       rs556734979       rs556897543       rs557036763       rs557370944       rs558168341       rs558180067       rs559245433       rs559767938       rs559999556       rs560111316       rs560184964       rs560253798       rs560400819       rs561073114       rs561205427       rs561328965       rs561513247       rs561600005       rs561732568       rs562080231       rs562336405       rs562509494       rs562522450       rs562569924       rs563713823       rs563788931       rs564402414       rs565154262       rs565455629       rs565470782       rs565518243       rs565527258       rs565562046       rs565745608       rs565872125       rs566103739       rs566201110       rs566215865       rs566466740       rs566476430       rs566476824       rs566536535       rs566857785       rs567174630       rs567450542       rs567548325       rs567659056       rs569372327       rs569886383       rs570090113       rs570164402       rs570637450       rs570713444       rs571113443       rs571670080       rs571672055       rs572086468       rs572133293       rs573490579       rs573517819       rs573542764       rs573604689       rs574300031       rs574638289       rs574639923       rs574699611       rs574702639       rs574884246       rs575538449       rs575752785       rs575930606       rs576317920       rs576326113       rs576378756       rs576781708       rs576912648       rs577238931       rs577350541       rs577584309       rs578063479       rs745769915       rs746147492       rs746347123       rs746450009       rs747039900       rs747204459       rs747294673       rs747825121       rs747901870       rs748048090       rs748119641       rs748198710       rs748247973       rs748756211       rs748917392       rs748978249       rs749007247       rs749605831       rs749699113       rs749815196       rs750079881       rs750191449       rs750450795       rs750622583       rs750944163       rs751028209       rs751149956       rs751198098       rs752215871       rs752593595       rs752907397       rs753225892       rs753546545       rs753832762       rs753833000       rs754461118       rs754507565       rs754531104       rs755016099       rs755233987       rs755348321       rs755882372       rs756141192       rs756160302       rs756454450       rs756498779       rs756782667       rs757630639       rs758030895       rs758187154       rs758205665       rs758870694       rs759295229       rs759443369       rs759636003       rs759933555       rs760095816       rs760151426       rs760263887       rs760570692       rs761064278       rs761661785       rs761798325       rs762143821       rs762286502       rs762459197       rs762833357       rs762843755       rs763163192       rs763214720       rs763625180       rs763666467       rs764777005       rs765370716       rs765902215       rs766256150       rs766339492       rs766346039       rs766771957       rs767097742       rs767388872       rs767728531       rs768059525       rs768078073       rs768296718       rs768428419       rs768501392       rs768554764       rs769110348       rs769573688       rs769607319       rs769846587       rs770146835       rs770299114       rs770829389       rs770919061       rs771187748       rs771242039       rs771421684       rs771551065       rs771957958       rs772050680       rs772181608       rs772372352       rs772749942       rs773480726       rs773666920       rs774172039       rs774332779       rs774372228       rs774529465       rs774617467       rs775498598       rs775986521       rs775986954       rs776240975       rs776620783       rs777000868       rs777019391       rs777121328       rs777429602       rs777437512       rs778138934       rs778379691       rs778452912       rs778539657       rs778623638       rs778643769       rs778730371       rs779205556       rs780073308       rs780083129       rs780441947       rs780592963       rs780921502       rs781009510       rs781114268       rs781468557       rs781501457       rs781590256      

基因表达

基因表达

CST1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ACCATATGTACCAAGTCCCA
58
GCACAACTGTTTCTTCTGC
58
TATGTACCAAGTCCCAGCC
59
AAGAGCACAACTGTTTCTTCTG
60
ATATGTACCAAGTCCCAGCC
59
AGAGCACAACTGTTTCTTCTG
59
ACCATATGTACCAAGTCCCA
58
GCACAACTGTTTCTTCTGC
58
ATATGTACCAAGTCCCAGCC
59
AGAGCACAACTGTTTCTTCTG
59
TATGTACCAAGTCCCAGCC
59
AAGAGCACAACTGTTTCTTCTG
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CST1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CST1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001580
P01037(UniProtKB)
IDA
GO:0004869
P01037(UniProtKB)
IEA
GO:0005515
P01037(UniProtKB)
IPI
GO:0005615
P01037(UniProtKB)
IDA
GO:0005615
P01037(UniProtKB)
IDA
GO:0005615
P01037(UniProtKB)
IDA
GO:0010951
P01037(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CST1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Hay fever 0.120271442 1 0 BeFree_CTD_human
Prostatic Neoplasms 0.12 1 0 CTD_human
Stomach Neoplasms 0.12 1 0 CTD_human
Diabetes Mellitus, Non-Insulin-Dependent 0.002367032 1 0 GAD
Colorectal Carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Carcinogenesis 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Colonic Neoplasms 0.000271442 1 0 BeFree
Cyst 0.000271442 1 0 BeFree
Bacterial Vaginosis 0.000271442 1 0 BeFree
brain cyst 0.000271442 1 0 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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