CPA1(carboxypeptidase A1 (pancreatic))

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

基因染色体位置

基因染色体位置

7q32

基因简述

基因简述

This gene encodes a member of the carboxypeptidase A family of zinc metalloproteases. This enzyme is produced in the pancreas and preferentially cleaves C-terminal branched-chain and aromatic amino acids from dietary proteins. This gene and several family members are present in a gene cluster on chromosome 7. Mutations in this gene may be linked to chronic pancreatitis, while elevated protein levels may be associated with pancreatic cancer. [provided by RefSeq, Jan 2015]

[中文简述(自动翻译):]  该基因编码的羧成员锌金属蛋白酶家族。这种酶在胰腺产生和优先切割C-末端支链和从膳食蛋白质芳香族氨基酸。该基因和几个M组余烬存在于染色体上的7突变该基因可能与慢性胰腺炎的基因簇，而升高的蛋白水平可以与胰腺癌相关联。 [由RefSeq的，2015年1月提供]

OMIM数据库中对CPA1基因的介绍     Wikipedia数据库中对CPA1基因的介绍

基因序列

基因序列

CPA1基因的碱基序列：[NCBI]

基因突变

基因突变

CPA1基因的碱基突变：           显示全部snp
rs741486       rs741487       rs968404       rs1126899       rs2239604       rs2239606       rs2268381       rs2268382       rs2284682       rs3043750       rs3757405       rs3807136       rs6972781       rs7779201       rs7789785       rs7790688       rs7811409       rs10215193       rs10263705       rs10954269       rs11560388       rs12706927       rs13226219       rs17169627       rs17330508       rs17849959       rs28741972       rs34457825       rs34469752       rs34474469       rs34843162       rs34875501       rs34925618       rs35325022       rs41274173       rs41274176       rs55782920      
rs60012860       rs61735156       rs61735158       rs61735962       rs71527959       rs73484529       rs74467115       rs74637576       rs74972479       rs75426882       rs76090993       rs77652728       rs77792157       rs78978361       rs111326506       rs111332545       rs111500524       rs111525993       rs111728119       rs112860644       rs113061008       rs113487769       rs113805190       rs113897136       rs113898380       rs114294426       rs114327169       rs114365673       rs114488732       rs114749558       rs115663631       rs115987393       rs116210766       rs116214014       rs117121471       rs117732443       rs138021189       rs138408893       rs138409610       rs139022834       rs139588855       rs139594743       rs139627220       rs139667336       rs139718836       rs140135840       rs140633988       rs141209213       rs141400125       rs141886698       rs142025330       rs142112054       rs142127319       rs143162896       rs144331247       rs144546424       rs144988958       rs145592551       rs145916805       rs145988366       rs146310023       rs146357579       rs146503075       rs147515901       rs147570641       rs147790644       rs148329227       rs148908145       rs149107854       rs149265772       rs149470727       rs149639051       rs149743283       rs149774597       rs149795627       rs150092860       rs150333128       rs150556703       rs150608753       rs150653308       rs151142635       rs180749875       rs181260302       rs181409889       rs181859202       rs181927927       rs182456659       rs183165867       rs183206711       rs183326271       rs183429188       rs184981267       rs185091162       rs185345253       rs186183069       rs186407335       rs186470325       rs186642528       rs186720065       rs187843251       rs190000445       rs190269715       rs190270374       rs190688301       rs190956070       rs191494303       rs192484041       rs192954083       rs199693974       rs199744828       rs199761591       rs199883384       rs200036285       rs200161199       rs200317425       rs200645380       rs200717942       rs200825455       rs201117743       rs201165629       rs201257089       rs201291043       rs201332778       rs201705049       rs201750163       rs201893877       rs201936657       rs202029176       rs202068577       rs368106753       rs368139803       rs368581566       rs368689434       rs369058363       rs369211972       rs369392256       rs369479305       rs369618200       rs369665148       rs370049711       rs370058970       rs370268037       rs370302338       rs371243612       rs371545225       rs372056259       rs372131401       rs372247084       rs373095658       rs373471930       rs373588913       rs373943982       rs374031429       rs374265355       rs374288271       rs374313337       rs374411015       rs374458437       rs375136235       rs375166731       rs375614906       rs375620015       rs375929600       rs376018006       rs376189548       rs376580671       rs376743118       rs377042960       rs377138792       rs377290476       rs377654542       rs377691213       rs527680628       rs527681708       rs527945334       rs528090655       rs528129809       rs528349371       rs528877594       rs529373594       rs530351738       rs530486681       rs530634533       rs531448106       rs531877566       rs531915568       rs531960313       rs531999330       rs532593661       rs532604094       rs532631461       rs532987707       rs533352347       rs533389472       rs534148807       rs534330209       rs534719305       rs534753328       rs534875581       rs535284895       rs535512083       rs535669701       rs535833395       rs535853798       rs535901465       rs536304644       rs536501882       rs536632789       rs537076438       rs537101237       rs537519042       rs538046845       rs538086831       rs538269503       rs539608557       rs540063110       rs540251433       rs541011805       rs541369703       rs541547126       rs541913287       rs541961514       rs542036318       rs542422982       rs542467265       rs542634499       rs542840518       rs542963638       rs543024432       rs543060184       rs543061149       rs543227329       rs543439612       rs544170970       rs544590173       rs545428935       rs545564691       rs545564740       rs545968608       rs546019879       rs546599518       rs546958766       rs546994995       rs547132929       rs547494481       rs547564304       rs548306438       rs548784367       rs549691143       rs549935568       rs549974337       rs550597171       rs550639215       rs550709882       rs550805841       rs551133281       rs551169951       rs551715341       rs551808400       rs552533046       rs552859879       rs552887737       rs553171094       rs553278687       rs553356067       rs553493401       rs553679491       rs555045616       rs555082859       rs555894669       rs555963199       rs555996312       rs556021185       rs556851538       rs557631781       rs558349941       rs558570962       rs558657491       rs558744508       rs558842378       rs558847194       rs558885976       rs559471767       rs559606727       rs559663385       rs560006528       rs561099232       rs561296460       rs561407725       rs561649749       rs562662361       rs562783283       rs563356226       rs563357809       rs563418702       rs563692176       rs565092660       rs565231748       rs565451182       rs565602249       rs565719625       rs566822250       rs567145944       rs567186097       rs567258648       rs567887156       rs567931799       rs568410303       rs569001638       rs569326955       rs569595458       rs569677916       rs570416376       rs570466241       rs570700026       rs570738737       rs570775909       rs570988287       rs571026892       rs571755839       rs571768668       rs571982111       rs572018932       rs572262817       rs572986187       rs573587509       rs573651667       rs573718134       rs574196558       rs574607678       rs574733701       rs575004010       rs575540876       rs576217595       rs576227957       rs576257252       rs576425975       rs576863853       rs577008275       rs577085129       rs577187219       rs577517505       rs578146182       rs769989860       rs781784722       rs781788622       rs781790378       rs781791429       rs781794643       rs781796250       rs781799150       rs781799934       rs781803608       rs781805242       rs781805250       rs781815975       rs781816095       rs781818978       rs781820716       rs781827322       rs781840776       rs781846291       rs781849153       rs781853343       rs781859541       rs781860509       rs781864524       rs781867465       rs781868944       rs781880086       rs781880789       rs781887664       rs781892154       rs781892742       rs781893232       rs781895665       rs781904231       rs781906228       rs781910756       rs781912694       rs781915353       rs781918506       rs781922796       rs781928491       rs781929748       rs781931789       rs781932152       rs781941757       rs781943992       rs781953020       rs781953465       rs781953847       rs781963872       rs781965999       rs781967301       rs781968100       rs781968137       rs781975111       rs781977220       rs781980982       rs781983524       rs781986613       rs781990114       rs781993813       rs781996113       rs781998185       rs782000958       rs782001383       rs782003179       rs782005182       rs782006972       rs782007014       rs782014845       rs782018414       rs782024110       rs782029402       rs782032191       rs782040833       rs782046244       rs782047513       rs782049899       rs782052277       rs782053370       rs782055370       rs782056759       rs782063905       rs782067396       rs782070188       rs782076397       rs782077492       rs782083054       rs782085292       rs782092067       rs782095540       rs782104190       rs782112003       rs782125540       rs782133193       rs782136930       rs782139600       rs782140727       rs782142627       rs782150811       rs782152472       rs782152893       rs782157168       rs782157662       rs782158803       rs782164183       rs782164835       rs782165075       rs782168130       rs782170635       rs782178812       rs782180693       rs782186717       rs782190459       rs782198689       rs782211245       rs782213902       rs782218163       rs782223283       rs782224469       rs782224736       rs782225489       rs782225736       rs782231788       rs782234205       rs782239359       rs782248092       rs782248213       rs782250540       rs782255121       rs782257247       rs782257701       rs782263314       rs782268495       rs782276487       rs782278873       rs782284762       rs782284797       rs782286310       rs782290231       rs782290810       rs782291899       rs782301578       rs782303879       rs782305414       rs782311895       rs782313134       rs782313960       rs782314999       rs782320620       rs782325155       rs782329011       rs782329019       rs782329501       rs782331075       rs782335525       rs782338563       rs782343548       rs782346209       rs782356356       rs782356623       rs782366383       rs782369775       rs782373395       rs782384499       rs782391064       rs782393347       rs782397100       rs782403815       rs782404811       rs782408096       rs782410892       rs782412885       rs782417364       rs782419645       rs782420276       rs782422328       rs782426515       rs782426641       rs782427594       rs782430111       rs782430212       rs782434753       rs782438860       rs782440998       rs782444285       rs782449244       rs782457793       rs782458397       rs782465366       rs782466930       rs782468456       rs782468799       rs782472394       rs782478399       rs782486022       rs782487656       rs782487942       rs782489102       rs782491120       rs782496407       rs782496881       rs782503482       rs782503491       rs782510117       rs782511286       rs782525714       rs782530526       rs782530612       rs782535118       rs782539361       rs782539718       rs782550086       rs782555907       rs782556361       rs782561684       rs782570276       rs782571072       rs782573440       rs782574271       rs782577921       rs782581515       rs782582120       rs782588903       rs782589138       rs782591977       rs782595396       rs782597959       rs782603249       rs782603710       rs782607463       rs782611876       rs782614316       rs782619015       rs782627401       rs782637549       rs782637898       rs782638392       rs782645228       rs782645631       rs782647848       rs782651513       rs782658284       rs782663466       rs782667009       rs782668240       rs782671976       rs782674619       rs782675997       rs782679257       rs782686230       rs782686292       rs782689314       rs782689631       rs782693199       rs782702163       rs782706719       rs782710719       rs782716199       rs782717195       rs782718248       rs782718443       rs782718650       rs782721615       rs782722989       rs782736982       rs782740097       rs782740610       rs782742005       rs782745402       rs782746371       rs782749933       rs782752399       rs782755333       rs782758233       rs782766382       rs782770874       rs782776885       rs782783475       rs782788484       rs782790782       rs782790983       rs782791075       rs782797786       rs782805275       rs782805731       rs782809513       rs782810878       rs782816634       rs782817808      

基因表达

基因表达

CPA1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CAAAGAAGATCACTCAAGACTACG
60
CGATCTCCAGGAAGATGTCC
60
TACAGAAGATCACTCAAGACTACG
60
CGATCTCCAGGAAGATGTCC
60
CCCAGGTACAGAAGATCACTC
60
CCAGGAAGATGTCCAAGGT
59
GATCAGCTTTCCAAGGCTG
59
CACTGGCTTGATAAATTGCCT
59
CTGGAGGAGATCTATGACTTCC
59
TAGGTGTTGCCAATCTGGA
59
TGCAAAGAAGATCACTCAAGAC
59
GATCTCCAGGAAGATGTCCA
59
TCTTCCTGGAGATCGTCAC
59
CCAATACAGAGGGAGCCTG
60
TCAAGGCAATTTATCAAGCCAG
60
GAGCTCGAAGGTGAAGGAG
60
GGTACAGAAGATCACTCAAGAC
58
ATCTCCAGGAAGATGTCCA
57
CTGGAGGAGATCTATGACTTCC
59
TAGGTGTTGCCAATCTGGA
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CPA1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CPA1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004181
C9JQ63(UniProtKB)
IEA
GO:0006508
C9JQ63(UniProtKB)
IEA
GO:0008270
C9JQ63(UniProtKB)
IEA
GO:0004181
C9JUF9(UniProtKB)
IEA
GO:0006508
C9JUF9(UniProtKB)
IEA
GO:0008270
C9JUF9(UniProtKB)
IEA
GO:0004181
C9JUZ4(UniProtKB)
IEA
GO:0006508
C9JUZ4(UniProtKB)
IEA
GO:0008270
C9JUZ4(UniProtKB)
IEA
GO:0004181
P15085(UniProtKB)
IEA
GO:0005615
P15085(UniProtKB)
IDA
GO:0006508
P15085(UniProtKB)
IEA
GO:0008270
P15085(UniProtKB)
IEA
GO:0004181
S4R433(UniProtKB)
IEA
GO:0006508
S4R433(UniProtKB)
IEA
GO:0008270
S4R433(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CPA1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Pancreatitis, Chronic 0.120542884 2 0 BeFree_CTD_human
Adenoma 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000542884 2 0 BeFree
Pancreatitis 0.000542884 2 0 BeFree
Non-Neoplastic Disorder 0.000542884 2 0 BeFree
Adrenal Gland Hyperfunction 0.000271442 1 0 BeFree
Cushing Syndrome 0.000271442 1 0 BeFree
Mixed Salivary Gland Tumor 0.000271442 1 0 BeFree
Adrenocortical carcinoma 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Conn Syndrome 0.000271442 1 0 BeFree
TROPICAL CALCIFIC PANCREATITIS 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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