COX4I1(cytochrome c oxidase subunit IV isoform 1) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

16q24.1
基因染色体位置图

基因简述

基因简述

Cytochrome c oxidase (COX) is the terminal enzyme of the mitochondrial respiratory chain. It is a multi-subunit enzyme complex that couples the transfer of electrons from cytochrome c to molecular oxygen and contributes to a proton electrochemical gradient across the inner mitochondrial membrane. The complex consists of 13 mitochondrial- and nuclear-encoded subunits. The mitochondrially-encoded subunits perform the electron transfer and proton pumping activities. The functions of the nuclear-encoded subunits are unknown but they may play a role in the regulation and assembly of the complex. This gene encodes the nuclear-encoded subunit IV isoform 1 of the human mitochondrial respiratory chain enzyme. It is located at the 3' of the NOC4 (neighbor of COX4) gene in a head-to-head orientation, and shares a promoter with it. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  细胞色素C氧化酶（COX）是线粒体呼吸链的终端酶。它是一种多亚基酶复合物耦合电子从色素c转移到分子氧并有助于跨线粒体内膜的质子电化学梯度。该建筑群包括13个mitochondrial-和核编码亚基。线粒体的编码亚基进行电子传递和质子泵活动。核编码的亚基的功能是未知的，但它们可能在复杂的调节和组装的作用。该基因编码的人类线粒体呼吸链酶的核编码亚基IV亚型1。它位于NOC4（COX4的邻居）基因在一个头 - 头方向的3‘，和共享的启动子与它。 [由RefSeq的，2008年7月提供]

OMIM数据库中对COX4I1基因的介绍     Wikipedia数据库中对COX4I1基因的介绍

基因序列

基因序列

COX4I1基因的碱基序列：[NCBI]

基因突变

基因突变

COX4I1基因的碱基突变：           显示全部snp
rs4885       rs1800647       rs1803312       rs2072627       rs2075531       rs2075532       rs2075553       rs2233444       rs2233445       rs2233446       rs2233447       rs2233448       rs2233449       rs2233450       rs2233451       rs2599078       rs2599079       rs2599080       rs2599081       rs2599082       rs2599083       rs2599084       rs2599085       rs2599086       rs2599087       rs2599088       rs2599089       rs2599090       rs2599091       rs2599092       rs2599093       rs2599094       rs2599095       rs2641795       rs2641796       rs2641797       rs2641798      
rs2733955       rs2733956       rs2733957       rs2733958       rs2733959       rs2733960       rs2733961       rs2733962       rs2733963       rs2733964       rs2733965       rs2733966       rs2923563       rs2923564       rs5818557       rs7193393       rs7193554       rs7198313       rs8053730       rs9673638       rs9673646       rs9673792       rs10563131       rs11117402       rs11419687       rs11454415       rs11557185       rs11557187       rs11648858       rs13338794       rs61093966       rs71389145       rs73259065       rs74361728       rs74895046       rs75642777       rs76805068       rs77026588       rs77545028       rs77799470       rs79337262       rs79385561       rs79525318       rs111410079       rs111669022       rs112656021       rs112870681       rs113018222       rs113039680       rs113202317       rs113919456       rs114063976       rs114418268       rs115047678       rs115621621       rs116463753       rs116972724       rs116991031       rs117123269       rs118049090       rs137975688       rs138030816       rs138746510       rs138825412       rs139386023       rs139472465       rs139489638       rs139635993       rs139930428       rs140124307       rs140191888       rs141156381       rs141274846       rs141710669       rs141857699       rs142011518       rs142070470       rs142071938       rs142400268       rs142411703       rs142639416       rs142776923       rs143495191       rs144243506       rs144300062       rs144333119       rs144648869       rs144923867       rs145039479       rs145532035       rs145554841       rs145614952       rs145883032       rs146302679       rs146571924       rs146582440       rs146862566       rs146927270       rs146936146       rs147334152       rs147346083       rs147512107       rs147549369       rs147742137       rs147922224       rs148066312       rs148220134       rs148561189       rs148739411       rs148793654       rs148841925       rs148899206       rs149294473       rs149364130       rs149461099       rs149561742       rs149661499       rs149819018       rs150142001       rs150142897       rs150346368       rs150605730       rs151060694       rs180681071       rs180699095       rs181159405       rs182645016       rs182896227       rs183118839       rs183794256       rs183976364       rs184323956       rs184344520       rs184745241       rs184841709       rs185111136       rs185321108       rs185614230       rs185731000       rs186003355       rs186065307       rs186481746       rs187001915       rs187235165       rs187263860       rs187847097       rs188383202       rs188856638       rs188868080       rs188914684       rs189397864       rs189671285       rs190147687       rs190230276       rs190440768       rs190972212       rs191325341       rs191698212       rs191821030       rs191969936       rs191982845       rs192240462       rs192425962       rs192535345       rs199796380       rs199880666       rs199978628       rs200457742       rs200479248       rs200718347       rs201058411       rs201147506       rs201313443       rs201630555       rs201890635       rs202146194       rs367714586       rs367882670       rs368133545       rs368729667       rs368976078       rs369581485       rs370265790       rs370588990       rs370929782       rs371038829       rs371402997       rs371404018       rs371429884       rs371758115       rs371834112       rs372008173       rs372971283       rs373295518       rs373552102       rs373734689       rs373925837       rs374099023       rs374125919       rs374390111       rs374921510       rs375272236       rs375329322       rs375895416       rs375950381       rs376218422       rs376530285       rs376741490       rs376741917       rs377521175       rs377678815       rs377718678       rs527887199       rs527955515       rs528082280       rs529195851       rs529511327       rs529843056       rs530309436       rs530620803       rs530680366       rs530680772       rs530989379       rs532083654       rs532217840       rs532281801       rs532350189       rs532686261       rs532985207       rs533050615       rs533437456       rs533486232       rs533559131       rs533657464       rs533788527       rs533933908       rs534126257       rs534290309       rs534642187       rs534887011       rs535020975       rs535022468       rs535163763       rs535219987       rs535381279       rs536256121       rs536334272       rs537458885       rs537533562       rs537598289       rs537791176       rs537923346       rs538409401       rs539044545       rs539207920       rs539727402       rs539978958       rs540170877       rs540381526       rs540453934       rs540563272       rs540763473       rs540872431       rs541375905       rs541500480       rs541658960       rs542331735       rs543763355       rs543993682       rs544052410       rs544148414       rs544309971       rs545020654       rs545031596       rs545147795       rs545561413       rs545622736       rs545802040       rs545865288       rs546432216       rs546886544       rs546967678       rs547412007       rs547688719       rs547825423       rs548019640       rs548068402       rs548463575       rs548628187       rs549263294       rs549773715       rs550784564       rs550964101       rs550997883       rs551025732       rs552381537       rs552438151       rs552741620       rs553125199       rs553470190       rs553574132       rs553726862       rs553859737       rs554046841       rs554109238       rs554724117       rs555048051       rs555312255       rs556127141       rs556167682       rs556182929       rs556246394       rs556625714       rs556706914       rs557562393       rs557764128       rs558241415       rs558684277       rs558883489       rs558999182       rs559205038       rs560075289       rs560162218       rs560344539       rs560428992       rs560985710       rs561331286       rs561392387       rs561451264       rs561517226       rs562155866       rs562438109       rs562572761       rs562654800       rs562984993       rs563082965       rs563250127       rs563376246       rs563402299       rs563838844       rs563891758       rs564043341       rs564104109       rs564352962       rs564372819       rs564491905       rs564544220       rs565246656       rs565440696       rs565796244       rs565858274       rs566076942       rs566138523       rs566188741       rs566332243       rs566714865       rs566843546       rs566845938       rs566896331       rs567265710       rs567270876       rs567311575       rs567326688       rs567595889       rs567908829       rs567972214       rs568033425       rs568446272       rs568511286       rs568893833       rs569089672       rs569156205       rs569708992       rs569830870       rs570226938       rs570290692       rs570733331       rs571087818       rs571211362       rs571279401       rs571313813       rs571494171       rs571596451       rs571849755       rs572146090       rs572265084       rs572683948       rs572925077       rs573874022       rs573938612       rs573952529       rs574555020       rs574946540       rs575076952       rs575139893       rs576079415       rs576141348       rs576373586       rs576420230       rs577366722       rs577564525       rs577618111       rs577681704       rs578062416       rs578220606       rs745400280       rs745444271       rs745565759       rs745678886       rs745840387       rs746016496       rs746164704       rs746541450       rs746881682       rs746963034       rs747140383       rs747411276       rs747556114       rs747683244       rs747800437       rs748294695       rs748419646       rs748632617       rs748913859       rs748935054       rs748959830       rs749233847       rs749391143       rs749552922       rs749744523       rs750140438       rs750425972       rs750534183       rs750829937       rs750887449       rs750975329       rs751095989       rs751199603       rs751359351       rs751718635       rs751735685       rs751773705       rs751801715       rs751877897       rs751992713       rs752205006       rs752915473       rs752916404       rs752962325       rs753062638       rs753408068       rs753608262       rs753867498       rs754208296       rs754210286       rs754611348       rs754772407       rs754932066       rs755156430       rs755317854       rs755549888       rs755854485       rs755921814       rs756080790       rs756131951       rs756239305       rs756438050       rs756699286       rs756860726       rs756915909       rs757210652       rs757263492       rs757327852       rs757478293       rs757556403       rs757994903       rs758224726       rs758706913       rs758936363       rs759097832       rs759196736       rs759454863       rs759508701       rs759822214       rs759981105       rs760105835       rs760105911       rs760182902       rs761022513       rs761045604       rs761105401       rs761228315       rs761408632       rs761492668       rs761951269       rs762025888       rs762159019       rs762185757       rs762503301       rs762525610       rs762635117       rs762932616       rs762994090       rs763202122       rs763552061       rs764048670       rs764241094       rs764402410       rs764779280       rs764904216       rs765012514       rs765105753       rs765521065       rs765564558       rs765575648       rs765761702       rs766482547       rs766674752       rs766903896       rs766941591       rs767152742       rs767646220       rs767648238       rs767772859       rs768090930       rs768199307       rs768199794       rs768360785       rs768719849       rs768771110       rs768853744       rs769057810       rs769102627       rs769159647       rs769600744       rs769707012       rs769759027       rs769761034       rs770133953       rs770231214       rs770277920       rs770419022       rs770474032       rs770721766       rs770833137       rs770901016       rs770904356       rs771065408       rs771139213       rs771611429       rs771751860       rs772109393       rs772561167       rs772666331       rs773695111       rs773747888       rs773766728       rs774033649       rs774243085       rs774710244       rs774735860       rs774812052       rs774898740       rs775177240       rs775251888       rs775398027       rs776030186       rs776497546       rs776735855       rs776935149       rs777065486       rs777096470       rs777325740       rs777378862       rs777644605       rs777747061       rs777769340       rs777833430       rs777977232       rs778220898       rs778356222       rs778449832       rs778714969       rs779133332       rs779219247       rs779293114       rs779831701       rs780067773       rs780164636       rs780684895       rs781163506       rs781343693       rs781487417       rs781661744       rs576079415      

基因表达

基因表达

COX4I1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GGCTACCAGGGTATTTAGC
57
TTCACAACACTTTCATGAGC
57
GGCTACCAGGGTATTTAGC
57
TTCACAACACTTTCATGAGC
57
GAAGCACTATGTGTACGGC
58
CTTCATGTCCAGCATCCTC
58
AAGGCATTGAAGGAGAAGG
57
GAACTTAATGCGATACAACTCG
58
AAGGCATTGAAGGAGAAGG
57
GAACTTAATGCGATACAACTCG
58
TCCATGGATGAGAAAGTCGAG
60
AGGAAACACAGAGGCTTCC
60
GCTACCAGGGTATTTAGCCT
59
CTTCACAACACTTTCATGAGC
58
GCTTTGCTGAGATGAACAGG
60
CCAAGGTGACCATAGTGCT
59
AGAATGTTGGCTACCAGGG
59
CAACACTTTCATGAGCTCGT
59
GAAAGTGTTGTGAAGAGCG
57
CTTCAATGCCTTCTGGCTG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

COX4I1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

COX4I1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004129
H3BN72(UniProtKB)
IEA
GO:0005634
H3BN72(UniProtKB)
IDA
GO:0005739
H3BN72(UniProtKB)
IDA
GO:0016021
H3BN72(UniProtKB)
IEA
GO:1902600
H3BN72(UniProtKB)
IEA
GO:0004129
H3BNI5(UniProtKB)
IEA
GO:1902600
H3BNI5(UniProtKB)
IEA
GO:0004129
H3BNV9(UniProtKB)
IEA
GO:0005634
H3BNV9(UniProtKB)
IDA
GO:0005739
H3BNV9(UniProtKB)
IDA
GO:0016021
H3BNV9(UniProtKB)
IEA
GO:1902600
H3BNV9(UniProtKB)
IEA
GO:0004129
H3BPG0(UniProtKB)
IEA
GO:0016021
H3BPG0(UniProtKB)
IEA
GO:1902600
H3BPG0(UniProtKB)
IEA
GO:0004129
P13073(UniProtKB)
IEA
GO:0005515
P13073(UniProtKB)
IPI
GO:0005515
P13073(UniProtKB)
IPI
GO:0005634
P13073(UniProtKB)
IDA
GO:0005739
P13073(UniProtKB)
IDA
GO:0005739
P13073(UniProtKB)
IDA
GO:0005743
P13073(UniProtKB)
TAS
GO:0005751
P13073(UniProtKB)
IBA
GO:0006091
P13073(UniProtKB)
TAS
GO:0006123
P13073(UniProtKB)
IBA
GO:0006123
P13073(UniProtKB)
TAS
GO:0007584
P13073(UniProtKB)
IEA
GO:0016020
P13073(UniProtKB)
IDA
GO:0070062
P13073(UniProtKB)
IDA
GO:1902600
P13073(UniProtKB)
IEA
GO:0004129
Q86WV2(UniProtKB)
IEA
GO:0005515
Q86WV2(UniProtKB)
IPI
GO:1902600
Q86WV2(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控COX4I1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Leprosy 0.12 1 1 GWASCAT
Protein-Energy Malnutrition 0.08 1 0 RGD
Obesity 0.000814326 3 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Myopathy 0.000271442 1 0 BeFree
Cytochrome-c Oxidase Deficiency 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree

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基因相关文献

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