COMT(catechol-O-methyltransferase) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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22q11.21
基因染色体位置图

Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]

[中文简述(自动翻译):]  儿茶酚-O-甲基催化甲基从S-腺苷甲硫氨酸转移至儿茶酚胺,包括神经递质多巴胺,肾上腺素和去甲肾上腺素。此O-甲基化导致儿茶酚胺发射机的主要降解途径之一。除了其内源性物质的代谢作用,COMT是在高血压,哮喘,和帕金森病的治疗中使用儿茶酚药物的代谢重要。 COMT以两种形式在组织中,可溶形式的(S-COMT)和膜结合形式(MB-COMT)找到。的S-COMT和MB-COMT的区别驻留在N-末端内。几个转录变体通过使用替代翻译起始位点和启动子形成。 [由RefSeq的,2008年9月提供]

COMT基因的碱基序列:[NCBI]
COMT基因的碱基突变:           显示全部snp
rs9265       rs12814       rs14968       rs165599       rs165655       rs165728       rs165840       rs174697       rs174698       rs174699       rs362115       rs362204       rs1109436       rs4646318       rs5993889       rs9306235       rs9332369       rs9332370       rs9332371       rs9332372       rs9332373       rs9332374       rs9332375       rs9332376       rs9332377       rs9332378       rs9332380       rs9332381       rs9332382       rs9332383       rs9332384       rs12158230       rs13055002       rs35478083       rs35481270       rs35593000       rs36082074      
rs61143203       rs72547415       rs72547416       rs72552064       rs73387711       rs80244944       rs111361762       rs112696498       rs113499749       rs113895332       rs114509574       rs115408593       rs117222687       rs138327309       rs138918504       rs139449932       rs139471681       rs139797392       rs142164354       rs142741838       rs143378665       rs143759706       rs144463570       rs145166266       rs145308916       rs145653431       rs146143750       rs147296111       rs147371346       rs147632723       rs148230013       rs148667152       rs150537601       rs150590034       rs151284584       rs181836260       rs181896876       rs183643105       rs186490696       rs186490911       rs188300184       rs190149878       rs191017652       rs199743418       rs199744942       rs200150695       rs200322130       rs201407028       rs201476400       rs201656482       rs201893998       rs202017586       rs202111640       rs202238633       rs369589068       rs369908847       rs371134244       rs372521762       rs372535915       rs373882300       rs375546366       rs376273380       rs376880156       rs397758621       rs527388400       rs528932065       rs529860138       rs529947354       rs530009419       rs530394675       rs531216737       rs531276653       rs531307859       rs531680429       rs532505190       rs532621286       rs533573617       rs534433745       rs534487632       rs534926620       rs535868598       rs535897884       rs536538848       rs536753773       rs536946851       rs536959884       rs537415012       rs537552073       rs540916953       rs540964401       rs542725783       rs545120429       rs545652531       rs545766664       rs545915950       rs546072238       rs546104104       rs546326145       rs546597649       rs548235125       rs549431463       rs550339713       rs550545168       rs550972620       rs551201247       rs551937723       rs552180875       rs552765887       rs552918424       rs554056486       rs555126080       rs555457967       rs556404244       rs556544357       rs557457134       rs557593950       rs558181873       rs559196689       rs559691932       rs559908437       rs560296967       rs560471850       rs561135670       rs562125892       rs562485525       rs562927287       rs563015027       rs566389623       rs566414524       rs567278485       rs567483468       rs567660279       rs567830018       rs569006363       rs569734418       rs570129778       rs570666030       rs570852533       rs571064504       rs571126788       rs571240696       rs571624971       rs572098963       rs572344937       rs572425011       rs572894585       rs574555015       rs575986934       rs576178460       rs576328138       rs577100720       rs577237896       rs745628165       rs745909655       rs747375116       rs748900622       rs749349777       rs749437638       rs749980102       rs750159038       rs750361935       rs750888068       rs751384934       rs751479802       rs752035611       rs752040355       rs752185888       rs753368847       rs753519008       rs754031677       rs754435205       rs754523899       rs755787901       rs755852074       rs757163724       rs757230347       rs757585867       rs758703641       rs759530867       rs759745492       rs759852947       rs760438359       rs760480469       rs760630494       rs760963988       rs761439220       rs761850766       rs762225948       rs762414852       rs762482920       rs762949433       rs764098677       rs764190673       rs764628606       rs765203563       rs765416306       rs766005856       rs766025497       rs767422215       rs767437774       rs768034116       rs768425882       rs768651434       rs769605719       rs769932706       rs770652365       rs772260799       rs772665216       rs773064787       rs773258890       rs773725345       rs774375300       rs774464882       rs774694408       rs775072525       rs775094798       rs775160442       rs775712233       rs776763589       rs776764330       rs777714694       rs778615118       rs778861844       rs779351993       rs779620718       rs780473420       rs781141235       rs781417317       rs781428653       rs4633       rs4680       rs4818       rs6267       rs6268       rs6269       rs6270       rs165631       rs165656       rs165722       rs165737       rs165767       rs165774       rs165879       rs165895       rs174673       rs174674       rs174675       rs174677       rs174678       rs174680       rs174681       rs174682       rs174683       rs174684       rs174685       rs174686       rs174687       rs174688       rs174689       rs174690       rs174691       rs174692       rs174693       rs174694       rs174695       rs174696       rs361574       rs361699       rs737864       rs737865       rs737866       rs739368       rs740601       rs740602       rs740603       rs769223       rs769224       rs933269       rs933270       rs933271       rs1055503       rs1544325       rs1800706       rs2020917       rs2075507       rs2239393       rs3081740       rs3081741       rs3081743       rs3087869       rs3218737       rs3788319       rs3788321       rs3810595       rs3819619       rs3819621       rs3841769       rs4646310       rs4646311       rs4646312       rs4646313       rs4646315       rs4646316       rs4646317       rs4986871       rs5031015       rs5746849       rs5844401       rs5844402       rs5992496       rs5992497       rs5992499       rs5992500       rs5992501       rs5993879       rs5993881       rs5993882       rs5993883       rs5993884       rs5993886       rs5993887       rs5993888       rs6518593       rs7287550       rs7290221       rs7291003       rs8140835       rs8140865       rs8185002       rs8192488       rs9306231       rs9306232       rs9306233       rs9306234       rs9332307       rs9332310       rs9332311       rs9332312       rs9332313       rs9332314       rs9332315       rs9332316       rs9332317       rs9332318       rs9332319       rs9332321       rs9332322       rs9332323       rs9332325       rs9332327       rs9332328       rs9332331       rs9332332       rs9332333       rs9332334       rs9332336       rs9332337       rs9332338       rs9332339       rs9332340       rs9332342       rs9332343       rs9332344       rs9332346       rs9332347       rs9332348       rs9332349       rs9332350       rs9332351       rs9332352       rs9332353       rs9332354       rs9332355       rs9332356       rs9332357       rs9332358       rs9332359       rs9332360       rs9332361       rs9332362       rs9332363       rs9332364       rs9332365       rs9332366       rs9332367       rs9332368       rs9605040       rs9606193       rs9606194       rs9606196       rs9617852       rs9680656       rs11089323       rs11569715       rs11569716       rs11569717       rs11569718       rs11569719       rs11569720       rs11569721       rs11703339       rs11703431       rs11704299       rs11912354       rs11912495       rs11913025       rs12053782       rs13054814       rs13306278       rs13306279       rs13306280       rs13306281       rs16982842       rs16982844       rs28565095       rs28621910       rs28804429       rs34068292       rs34218527       rs34234839       rs34300220       rs34446512       rs34450201       rs34663805       rs34686565       rs34691071       rs34798238       rs34819182       rs34937293       rs34966851       rs35014456       rs35280052       rs35527466       rs35558779       rs35617967       rs35777291       rs35788262       rs35791904       rs35919169       rs35958727       rs45454096       rs45478499       rs45511293       rs45521239       rs45535931       rs45536341       rs45551837       rs45553733       rs45559342       rs45581136       rs45593642       rs45604238       rs45616631       rs55653258       rs56104268       rs56901835       rs57039617       rs57384068       rs57714936       rs58155206       rs60214071       rs60481381       rs61484427       rs61910731       rs66578812       rs67723095       rs71186636       rs71186638       rs71312726       rs71312727       rs71317164       rs71317165       rs72547447       rs72547471       rs72549225       rs72554680       rs72556506       rs72563160       rs73385647       rs73385665       rs73880029       rs74392531       rs74451762       rs74745580       rs75012854       rs75972414       rs76140898       rs76157168       rs76384862       rs76452330       rs76599029       rs77080003       rs77139602       rs77825904       rs77839981       rs78091679       rs78405422       rs78977979       rs79019435       rs79048885       rs111359353       rs111377305       rs111450487       rs111567310       rs111744769       rs111751566       rs112080665       rs112087456       rs112092169       rs112169796       rs112470783       rs112501772       rs112606844       rs112812954       rs112913620       rs112960523       rs113043756       rs113047423       rs113099378       rs113208254       rs113208324       rs113282059       rs113400134       rs113402076       rs113583335       rs113706839       rs113739446       rs113917591       rs114214004       rs114218105       rs114824566       rs115252241       rs115419248       rs115770940       rs115794150       rs115954975       rs115957127       rs116375524       rs116745811       rs116969180       rs116974546       rs117179536       rs117374421       rs117464292       rs117484100       rs118020797       rs118063473       rs137931806       rs138042343       rs138056183       rs138352667       rs138433986       rs138476598       rs138628382       rs138696259       rs138763393       rs138764374       rs138781316       rs138847990       rs139188851       rs139227383       rs139265950       rs139652330       rs140023942       rs140215652       rs140236363       rs140522525       rs140673818       rs140814567       rs140981094       rs141294168       rs141726378       rs141752291       rs141777138       rs141796830       rs141865801       rs142426081       rs142527579       rs142545956       rs142785527       rs142882318       rs142999195       rs143035823       rs143083716       rs143214934       rs143293183       rs143335157       rs143796112       rs144143786       rs144287189       rs144570896       rs144603820       rs144623972       rs144825098       rs145133053       rs145228139       rs145561434       rs145588370       rs146023292       rs146033898       rs146251468       rs146658977       rs146682920       rs146817634       rs146908456       rs147086874       rs147452686       rs147609321       rs147840245       rs147863086       rs147942364       rs147945742       rs148047711       rs148304737       rs148490074       rs148543216       rs148620887       rs148742700       rs148796968       rs149256659       rs149425443       rs149748867       rs149813069       rs149909767       rs150137510       rs150437940       rs150613172       rs150925099       rs151117263       rs151129195       rs151296620       rs180816309       rs180991698       rs181006572       rs181069484       rs181168584       rs181173562       rs181300814       rs181626135       rs181695834       rs181838253       rs181946052       rs182242505       rs182351671       rs182354502       rs182565499       rs182624526       rs182726735       rs182840794       rs183018521       rs183178712       rs183188011       rs183207785       rs183349916       rs183886400       rs183978931       rs184250096       rs184481435       rs184647412       rs184656757       rs184657615       rs184809611       rs184831631       rs184896320       rs184941140       rs185480260       rs185596714       rs185602537       rs185645252       rs185762643       rs186338951       rs186490805       rs186538805       rs186688131       rs186818577       rs187119821       rs187125475       rs187145712       rs187249422       rs187264383       rs187288737       rs187362455       rs187514304       rs187733375       rs187763550       rs187869716       rs187939759       rs188086045       rs188159376       rs188233565       rs188402271       rs188411027       rs188540887       rs188704143       rs188735187       rs188812064       rs188875826       rs188978567       rs189109050       rs189167881       rs189402585       rs189627712       rs189771527       rs189789021       rs190003301       rs190020863       rs190086870       rs190541104       rs190562616       rs190698138       rs190825765       rs190860590       rs191009469       rs191012542       rs191111453       rs191184800       rs191204865       rs191409258       rs191426199       rs191573906       rs191585909       rs191619546       rs192082627       rs192111334       rs192231081       rs192298672       rs192451910       rs192752809       rs192895597       rs192967680       rs193013612       rs193188709       rs199590736       rs199637204       rs199690157       rs199710929       rs199755426       rs200563082       rs200975228       rs201225516       rs201616499       rs201641100       rs201835143       rs201922528       rs367860001       rs368039030       rs368058751       rs368145153       rs368292747       rs368330320       rs368509495       rs368616155       rs368816663       rs368878365       rs369035502       rs370533166       rs370538621       rs370819229       rs371344497       rs371877511       rs372065112       rs372065401       rs372093597       rs372316262       rs372399766       rs372825934       rs372972951       rs373060826       rs373157485       rs373356202       rs373404261       rs373434142       rs373611092       rs373922169       rs374053855       rs374506541       rs374941634       rs374989482       rs375558228       rs376114841       rs376460351       rs376721753       rs377353154       rs377403244       rs377404687       rs377574270       rs397738638       rs397817767       rs397897505       rs527442523       rs527505005       rs527562945       rs527571449       rs527630674       rs527641157       rs527763112       rs528022840       rs528107433       rs528217188       rs528300515       rs528687382       rs528729634       rs528821561       rs528894713       rs528907708       rs528992419       rs529089350       rs529103394       rs529201063       rs529261258       rs529395933       rs529410576       rs529621431       rs529690481       rs529787200       rs529830149       rs529833366       rs530294648       rs530418038       rs530456300       rs530524098       rs530544509       rs530684989       rs531086875       rs531355343       rs531567269       rs531623890       rs531678754       rs531738788       rs532128234       rs532279581       rs532340383       rs532354880       rs532405664       rs532617540       rs532822625       rs532835699       rs532884670       rs532898989       rs532959612       rs533149515       rs533154385       rs533164761       rs533176918       rs533280808       rs533736433       rs534008077       rs534019058       rs534063507       rs534349323       rs534688471       rs534967866       rs535400135       rs535581609       rs535654975       rs535737562       rs535746710       rs535775707       rs536030833       rs536590760       rs536817064       rs536872834       rs536930374       rs536959927       rs537200428       rs537261216       rs537261441       rs537384198       rs537727187       rs537736631       rs537928670       rs537941380       rs538130592       rs538195344       rs538254855       rs538400392       rs538740622       rs538956501       rs538969067       rs538990524       rs538993898       rs539052047       rs539178517       rs539181989       rs539205383       rs539242513       rs539504120       rs539636463       rs539754664       rs540137352       rs540184073       rs540207628       rs540239927       rs540325644       rs540336198       rs540505908       rs540589103       rs540703508       rs540752141       rs540850792       rs540974954       rs540997481       rs541134681       rs541173058       rs541221832       rs541306902       rs541369456       rs541509295       rs541544546       rs541752907       rs541753227       rs541848833       rs542074956       rs542099468       rs542330631       rs542382033       rs542518988       rs542522271       rs542566874       rs542626343       rs543103885       rs543116174       rs543135196       rs543291656       rs543339834       rs543355419       rs543417113       rs543431264       rs543564022       rs543616885       rs543896821       rs543934306       rs543970278       rs544148153       rs544149826       rs544169194       rs544306540       rs544706516       rs544846648       rs544882417       rs544942987       rs545037414       rs545497036       rs545500043       rs545562362       rs545734814       rs545802763       rs545892924       rs545892956       rs546053814       rs546384463       rs546473665       rs546486072       rs546845133       rs546897967       rs547048962       rs547306810       rs547476716       rs547490767       rs547704901       rs547715475       rs548010844       rs548118368       rs548169009       rs548187718       rs548231559       rs548251685       rs548460607       rs548485215       rs548596792       rs548598033       rs548612578       rs548624239       rs548679849       rs548734423       rs548774062       rs549145852       rs549728841       rs549799790       rs550002408       rs550005778       rs550048121       rs550109761       rs550274150       rs550403035       rs550647879       rs550928551       rs551012440       rs551248812       rs551312068       rs551564927       rs551990363       rs552024017       rs552112055       rs552227322       rs552299736       rs552458800       rs552514363       rs552584428       rs552664785       rs552801657       rs552863620       rs552865451       rs552907432       rs552918424       rs552952129       rs552979711       rs553432501       rs553773000       rs553783557       rs553831782       rs553848659       rs553864473       rs553919769       rs553932083       rs554022938       rs554245932       rs554329943       rs554588029       rs554787880       rs554806142       rs555122417       rs555247050       rs555296170       rs555373780       rs555437903       rs555598433       rs555623141       rs555713096       rs555945529       rs556004212       rs556229309       rs556231205       rs556436120       rs556520712       rs556696903       rs556805221       rs556859704       rs557094660       rs557122575       rs557166004       rs557266432       rs557371831       rs557420962       rs557432323       rs557591012       rs557656191       rs557852768       rs557915474       rs557956002       rs557980709       rs558196334       rs558390204       rs558421487       rs558449052       rs558523036       rs558571441       rs558606072       rs558899650       rs558962880       rs558998170       rs559027962       rs559049307       rs559073578       rs559605765       rs559611471       rs559727077       rs559813983       rs559921342       rs560145776       rs560208339       rs560370814       rs560540203       rs560597340       rs560665179       rs560706836       rs560741879       rs560751478       rs560839535       rs561326070       rs561449386       rs561507843       rs561536243       rs561538819       rs561731053       rs561792361       rs561990876       rs562153643       rs562198269       rs562298402       rs562338081       rs562527420       rs562533906       rs562546579       rs562666916       rs562735138       rs562801159       rs563006210       rs563143124       rs563180100       rs563298832       rs563381182       rs563519604       rs563567650       rs563613884       rs563626716       rs563658418       rs563674397       rs563736535       rs563769624       rs564039846       rs564190137       rs564190153       rs564321052       rs564321527       rs564371185       rs564387363       rs564481538       rs564524561       rs564712075       rs564729137       rs564767946       rs565194464       rs565340849       rs565399181       rs565400969       rs565934440       rs565954323       rs566115500       rs566477390       rs566681525       rs566883548       rs566971487       rs566981159       rs567122533       rs567126595       rs567662145       rs567826469       rs567862500       rs567952010       rs568047540       rs568074400       rs568139952       rs568188792       rs568198742       rs568400800       rs568691813       rs568721838       rs568878213       rs568938820       rs569026073       rs569039957       rs569280596       rs569283361       rs569612849       rs569676165       rs569697628       rs569761105       rs569785221       rs569912093       rs569922415       rs569924177       rs570418008       rs570473033       rs570586498       rs570675548       rs570743767       rs570804799       rs570899319       rs570959487       rs570974363       rs570980173       rs571085983       rs571089153       rs571170199       rs571516258       rs571569262       rs571937652       rs572081071       rs572122011       rs572292807       rs572441115       rs572487155       rs572506637       rs572527411       rs572572864       rs572612611       rs572699131       rs572834659       rs572836479       rs572935327       rs572964763       rs572989425       rs573201671       rs573285888       rs573325551       rs573430886       rs573490163       rs573756533       rs573959326       rs573968094       rs573980323       rs574216987       rs574219932       rs574375445       rs574638835       rs574751476       rs575036605       rs575110498       rs575123756       rs575139484       rs575273220       rs575463147       rs575989737       rs576085240       rs576088937       rs576148241       rs576283005       rs576583314       rs576769259       rs576903692       rs577156320       rs577321209       rs577634786       rs577761616       rs577917008       rs577924280       rs577949606       rs578079831       rs578130452       rs578147196       rs745341289       rs745447925       rs745493295       rs745542046       rs745747865       rs745812806       rs746224273       rs746487090       rs746604009       rs746764639       rs746938556       rs747016982       rs747273077       rs748066830       rs748298389       rs748587418       rs748686023       rs749053677       rs749057584       rs749158838       rs749246793       rs749349703       rs749544037       rs750093544       rs750232064       rs750428117       rs750490382       rs750490411       rs750684179       rs751186737       rs751619226       rs751999652       rs752384128       rs752620960       rs752902717       rs753104108       rs753302283       rs753372657       rs753820115       rs753856814       rs754096654       rs754242441       rs754305862       rs754397556       rs754436726       rs754664014       rs754869536       rs755100597       rs755245483       rs755441377       rs755663926       rs755825980       rs756024508       rs756145905       rs756235784       rs756452923       rs756499908       rs756769871       rs756963573       rs757034165       rs757073571       rs757163626       rs757427295       rs757782035       rs757861911       rs757949902       rs758079572       rs758271838       rs758503929       rs759091417       rs759181324       rs759305975       rs759340648       rs759939161       rs759968047       rs760129457       rs760266742       rs760319342       rs760348397       rs760406990       rs760676485       rs760899191       rs761093019       rs761297531       rs761347230       rs761388323       rs761671459       rs761850855       rs762297267       rs762599605       rs762799183       rs762906080       rs763187081       rs763427055       rs763613355       rs764392202       rs764440706       rs764545114       rs764846399       rs765045592       rs765052408       rs765385973       rs765538067       rs765568181       rs765914859       rs766020740       rs766377984       rs766448975       rs766469681       rs766960420       rs767059516       rs767066477       rs767140410       rs767632109       rs767705110       rs767971588       rs768039922       rs768254194       rs768277844       rs768474006       rs768578574       rs768611995       rs768636039       rs768889221       rs769293375       rs769380356       rs769492487       rs769516943       rs769606095       rs769700444       rs769710063       rs770045596       rs770504262       rs770596060       rs770700364       rs771850671       rs772083227       rs772548253       rs772562103       rs772593398       rs772880300       rs772965142       rs773235901       rs773373201       rs773569271       rs773751730       rs773889872       rs773917910       rs774007307       rs774265748       rs774500122       rs774711987       rs775234361       rs775355238       rs775392322       rs775710293       rs776094728       rs776281173       rs776476521       rs776957402       rs777226221       rs777441922       rs777507390       rs777650793       rs777720939       rs777724220       rs778030113       rs778219405       rs778309114       rs778495598       rs778498490       rs778579471       rs778881400       rs779163594       rs779542396       rs779543331       rs781018433       rs781045779       rs781266226       rs781461677       rs552952129      

COMT基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TTCTCTTGGAGGTGCAGTG
60
TCAGGGATACAGAAGACGTC
59
CAAGAAAGGCAAGATCGTGG
60
CTGAGTAGCCACAGTAGGC
60
CAGAGGTGCTTTGAAGATGC
60
AGGATGAACTCGTTCCAGC
60
TTCTCTTGGAGGTGCAGTG
60
AGGGAATGCATGAGTGAGG
60
ATCACCATCGAGATCAACCC
60
GAAGACCATGTCCAGTGTG
58
AGAGGTGCTTTGAAGATGC
58
CAGGATGAACTCGTTCCAG
58
TTCTCTTGGAGGTGCAGTG
60
GACTCAGGAGCCCAATCTG
60
GAGGTGCTTTGAAGATGCC
59
AGGATGAACTCGTTCCAGC
60
ATCACCATCGAGATCAACC
57
GAAGACCATGTCCAGTGTG
58
TCACCATCGAGATCAACCC
59
GAAGACCATGTCCAGTGTG
58
      尚未收录相关数据

COMT基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

COMT基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0000287
E7EMS6(UniProtKB)
IEA
GO:0006584
E7EMS6(UniProtKB)
IEA
GO:0016206
E7EMS6(UniProtKB)
IEA
GO:0032259
E7EMS6(UniProtKB)
IEA
GO:0032259
E7EMS6(UniProtKB)
IEA
GO:0042135
E7EMS6(UniProtKB)
IEA
GO:0000287
E7EUU8(UniProtKB)
IEA
GO:0006584
E7EUU8(UniProtKB)
IEA
GO:0016206
E7EUU8(UniProtKB)
IEA
GO:0032259
E7EUU8(UniProtKB)
IEA
GO:0032259
E7EUU8(UniProtKB)
IEA
GO:0042135
E7EUU8(UniProtKB)
IEA
GO:0008171
F8WBW9(UniProtKB)
IEA
GO:0032259
F8WBW9(UniProtKB)
IEA
GO:0008171
H7BZ45(UniProtKB)
IEA
GO:0032259
H7BZ45(UniProtKB)
IEA
GO:0000287
P21964(UniProtKB)
IEA
GO:0005515
P21964(UniProtKB)
IPI
GO:0005515
P21964(UniProtKB)
IPI
GO:0005515
P21964(UniProtKB)
IPI
GO:0005515
P21964(UniProtKB)
IPI
GO:0005515
P21964(UniProtKB)
IPI
GO:0005515
P21964(UniProtKB)
IPI
GO:0005515
P21964(UniProtKB)
IPI
GO:0005739
P21964(UniProtKB)
IEA
GO:0005829
P21964(UniProtKB)
TAS
GO:0005886
P21964(UniProtKB)
TAS
GO:0005886
P21964(UniProtKB)
TAS
GO:0007565
P21964(UniProtKB)
IEA
GO:0007612
P21964(UniProtKB)
IEA
GO:0007614
P21964(UniProtKB)
IEA
GO:0008168
P21964(UniProtKB)
TAS
GO:0008168
P21964(UniProtKB)
TAS
GO:0008171
P21964(UniProtKB)
TAS
GO:0008210
P21964(UniProtKB)
IEA
GO:0014070
P21964(UniProtKB)
IEA
GO:0016020
P21964(UniProtKB)
IDA
GO:0016021
P21964(UniProtKB)
IEA
GO:0016036
P21964(UniProtKB)
IEA
GO:0016206
P21964(UniProtKB)
TAS
GO:0030424
P21964(UniProtKB)
IEA
GO:0032259
P21964(UniProtKB)
TAS
GO:0032496
P21964(UniProtKB)
IEA
GO:0032502
P21964(UniProtKB)
IEA
GO:0035814
P21964(UniProtKB)
IEA
GO:0042135
P21964(UniProtKB)
IEA
GO:0042420
P21964(UniProtKB)
IEA
GO:0042493
P21964(UniProtKB)
IEA
GO:0043197
P21964(UniProtKB)
IEA
GO:0044297
P21964(UniProtKB)
IEA
GO:0045211
P21964(UniProtKB)
IEA
GO:0045963
P21964(UniProtKB)
IEA
GO:0048265
P21964(UniProtKB)
IEA
GO:0048609
P21964(UniProtKB)
IEA
GO:0048662
P21964(UniProtKB)
IEA
GO:0050668
P21964(UniProtKB)
IEA
GO:0051930
P21964(UniProtKB)
IEA
GO:0070062
P21964(UniProtKB)
IDA
GO:0070062
P21964(UniProtKB)
IDA
GO:0070062
P21964(UniProtKB)
IDA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控COMT基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Schizophrenia 0.345417491 275 10 BeFree_CTD_human_GAD_LHGDN
DiGeorge Syndrome 0.279553364 26 3 BeFree_CTD_human_GAD_LHGDN_ORPHANET
HEARING LOSS, CISPLATIN-INDUCED, SUSCEPTIBILITY TO 0.24 1 0 CTD_human_ORPHANET
Pain 0.236471695 35 6 BeFree_CTD_human_GAD_RGD
Bipolar Disorder 0.180627479 50 2 BeFree_CTD_human_GAD_LHGDN
Attention deficit hyperactivity disorder 0.17780732 61 16 BeFree_CTD_human_GAD
Panic Disorder 0.162449467 22 3 BeFree_CTD_human_GAD_LHGDN
Alcoholic Intoxication, Chronic 0.157100455 27 3 BeFree_CTD_human_GAD_LHGDN
Mammary Neoplasms 0.144161834 11 0 CTD_human_GAD_LHGDN
Shprintzen syndrome 0.134581916 45 3 BeFree_GAD_ORPHANET
Mental disorders 0.132410381 39 1 BeFree_CTD_human_GAD
Autistic Disorder 0.125276948 5 1 BeFree_CTD_human_GAD
22q11 Deletion Syndrome 0.124267125 8 1 BeFree_GAD_ORPHANET
Fetal Growth Retardation 0.122367032 2 0 CTD_human_GAD
Animal Mammary Neoplasms 0.122367032 2 0 CTD_human_GAD
Amphetamine-Related Disorders 0.122367032 2 0 CTD_human_GAD
Cocaine-Related Disorders 0.122367032 1 0 CTD_human_GAD
Liver carcinoma 0.120542884 2 0 BeFree_CTD_human
Pheochromocytoma 0.120271442 1 0 BeFree_CTD_human
Cognition Disorders 0.12 1 0 CTD_human
Prostatic Neoplasms 0.12 1 0 CTD_human
CONOTRUNCAL ANOMALY FACE SYNDROME 0.12 0 0 ORPHANET
22q11 partial monosomy syndrome 0.12 0 0 ORPHANET
Malignant neoplasm of breast 0.101172466 99 10 BeFree_GAD
Hypertensive disease 0.093006804 10 1 BeFree_GAD_LHGDN_RGD
Dyskinesia, Drug-Induced 0.082367032 2 0 GAD_RGD
Pre-Eclampsia 0.082367032 1 0 GAD_MGD
Parkinsonian Disorders 0.080814326 4 0 BeFree_RGD
Catalepsy 0.08 1 0 RGD
Diabetes Mellitus, Experimental 0.08 1 0 RGD
Parkinson Disease 0.057685225 28 1 BeFree_GAD_LHGDN
Mental Depression 0.037633407 41 14 BeFree_GAD
Obsessive-Compulsive Disorder 0.034352361 30 1 BeFree_GAD_LHGDN
Psychotic Disorders 0.032051342 48 3 BeFree_GAD_LHGDN
Alzheimer's Disease 0.026285049 11 0 BeFree_GAD_LHGDN
Fibromyalgia 0.023451079 16 2 BeFree_GAD_LHGDN
Breast Carcinoma 0.021172466 78 10 BeFree
Malignant neoplasm of prostate 0.021107791 13 6 BeFree_GAD
Congenital diverticulum of pharynx 0.018936256 8 0 GAD
Anxiety Disorders 0.016948948 45 4 BeFree_GAD
Tobacco Use Disorder 0.016569224 7 0 GAD
Fibroid Tumor 0.015731154 6 0 BeFree_GAD_LHGDN
Major Depressive Disorder 0.01560167 30 6 BeFree_GAD_LHGDN
Endometrial Neoplasms 0.015274147 5 0 GAD_LHGDN
Mood Disorders 0.014168516 20 2 BeFree_GAD_LHGDN
Marijuana Abuse 0.01408264 20 10 BeFree_GAD
Endometrial Carcinoma 0.014006695 12 3 BeFree_GAD
Malignant neoplasm of lung 0.012649486 8 1 BeFree_GAD
Malignant neoplasm of ovary 0.012649486 8 1 BeFree_GAD
Anorexia Nervosa 0.012082858 7 1 BeFree_GAD_LHGDN
As If Personality 0.01183516 5 0 GAD
Uterine Neoplasms 0.01183516 5 0 GAD
Personality Traits 0.01183516 5 0 GAD
Substance-Related Disorders 0.01183516 5 0 GAD
Nonorganic psychosis 0.011672 43 3 BeFree
Obesity 0.010553895 6 0 BeFree_GAD
Pain, Postoperative 0.009272631 10 0 BeFree_GAD
Depressive disorder 0.009229024 34 14 BeFree
Unipolar Depression 0.008414698 31 6 BeFree
Malignant neoplasm of urinary bladder 0.007915422 4 0 BeFree_GAD
Heroin Dependence 0.007915422 6 1 BeFree_GAD
Mental Retardation 0.00764398 4 0 BeFree_GAD
Vitiligo 0.00764398 4 0 BeFree_GAD
Colorectal Cancer 0.00764398 5 0 BeFree_GAD
Malignant neoplasm of liver 0.007372538 3 0 BeFree_GAD
Sleep Deprivation 0.007101096 3 0 GAD
Endometriosis 0.006905599 9 0 BeFree_GAD
Hallucinations 0.006362715 7 4 BeFree_GAD
Temporomandibular Joint Disorders 0.006362715 7 0 BeFree_GAD
Mammographic Density 0.006362715 7 6 BeFree_GAD
Headache 0.006091273 6 1 BeFree_GAD
Eating Disorders 0.005819831 4 2 BeFree_GAD
Narcolepsy 0.005819831 4 0 BeFree_GAD
Dyspepsia 0.005362824 1 0 BeFree_GAD_LHGDN
NEUROTICISM 0.005352893 11 1 BeFree_GAD
Low Back Pain 0.005276948 4 1 BeFree_GAD
Shoulder Pain 0.005276948 2 0 BeFree_GAD
Alcohol abuse 0.005276948 4 0 BeFree_GAD
Osteochondritis Dissecans 0.005157396 19 1 BeFree
PANIC DISORDER 1 0.005157396 19 3 BeFree
Venous Thrombosis 0.005091382 1 0 GAD_LHGDN
Antisocial behavior 0.005081451 10 1 BeFree_GAD
Prostate carcinoma 0.005081451 10 6 BeFree_GAD
Lymphoma, Non-Hodgkin 0.005005506 2 0 BeFree_GAD
Chromosome Aberrations 0.004734064 2 0 GAD
Chromosome Deletion 0.004734064 2 0 GAD
Esophageal Neoplasms 0.004734064 2 0 GAD
Chronic Fatigue Syndrome 0.004734064 2 0 GAD
Head and Neck Neoplasms 0.004734064 2 0 GAD
Laryngeal neoplasm 0.004734064 2 0 GAD
Memory Disorders 0.004734064 2 0 GAD
Mouth Neoplasms 0.004734064 2 0 GAD
Pharyngeal Neoplasms 0.004734064 2 0 GAD
Prenatal Exposure Delayed Effects 0.004734064 2 0 GAD
Psychoses, Substance-Induced 0.004734064 2 0 GAD
Weight Gain 0.004734064 2 0 GAD
Helicobacter Infections 0.004734064 2 0 GAD
Menopause present (finding) 0.004734064 2 0 GAD
Weight Gain Adverse Event 0.004734064 2 0 GAD
Migraine Disorders 0.004267125 7 2 BeFree_GAD
Dementia 0.004267125 8 1 BeFree_GAD
Dyskinetic syndrome 0.00408156 6 1 BeFree_LHGDN
Lingual-Facial-Buccal Dyskinesia 0.003995683 6 1 BeFree_GAD
Carcinogenesis 0.003800186 14 1 BeFree
MAJOR AFFECTIVE DISORDER 2 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 1 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 4 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 5 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 6 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 7 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 8 0.003724241 5 1 BeFree_GAD
MAJOR AFFECTIVE DISORDER 9 0.003724241 5 1 BeFree_GAD
Cardiovascular Diseases 0.003452799 5 0 BeFree_GAD
Impaired cognition 0.003257302 12 2 BeFree
Bulimia 0.003181358 4 2 BeFree_GAD
Intervertebral Disc Degeneration 0.003181358 3 0 BeFree_GAD
Psychotic symptom 0.002985861 11 1 BeFree
Atherosclerosis 0.002909916 2 0 BeFree_GAD
Renal Cell Carcinoma 0.002909916 2 0 BeFree_GAD
Kidney Failure, Acute 0.002909916 2 1 BeFree_GAD
Multiple Sclerosis 0.002909916 3 1 BeFree_GAD
Myocardial Infarction 0.002909916 2 1 BeFree_GAD
Oppositional Defiant Disorder 0.002909916 3 1 BeFree_GAD
Gilles de la Tourette syndrome 0.002909916 3 0 BeFree_GAD
Methamphetamine abuse 0.002909916 2 0 BeFree_GAD
Bladder Neoplasm 0.00272435 1 0 LHGDN
Colonic Neoplasms 0.00272435 1 0 LHGDN
Hereditary Nonpolyposis Colorectal Neoplasms 0.00272435 1 0 LHGDN
Wolfram Syndrome 0.00272435 1 0 LHGDN
Polyneuropathy 0.00272435 1 0 LHGDN
Depressive Symptoms 0.002714419 10 1 BeFree
Adenocarcinoma 0.002638474 2 1 BeFree_GAD
Alexithymia 0.002638474 1 0 BeFree_GAD
Diabetes Mellitus 0.002638474 2 0 BeFree_GAD
Diabetes Mellitus, Non-Insulin-Dependent 0.002638474 1 0 BeFree_GAD
Diarrhea 0.002638474 2 0 BeFree_GAD
Gastritis 0.002638474 1 0 BeFree_GAD
Herpes Simplex Infections 0.002638474 2 1 BeFree_GAD
Kidney Failure, Chronic 0.002638474 2 0 BeFree_GAD
Lymphoma 0.002638474 1 0 BeFree_GAD
Mycetoma 0.002638474 1 0 BeFree_GAD
Osteoporosis 0.002638474 2 0 BeFree_GAD
Personality Disorders 0.002638474 2 0 BeFree_GAD
Subarachnoid Hemorrhage 0.002638474 1 0 BeFree_GAD
Substance Withdrawal Syndrome 0.002638474 2 1 BeFree_GAD
Vomiting 0.002638474 2 1 BeFree_GAD
Depression, Postpartum 0.002638474 2 1 BeFree_GAD
Common Migraine 0.002638474 2 0 BeFree_GAD
Phobic anxiety disorder 0.002638474 2 1 BeFree_GAD
Hepatitis C, Chronic 0.002638474 1 0 BeFree_GAD
Hot flushes 0.002638474 2 1 BeFree_GAD
Heroin Abuse 0.002638474 2 1 BeFree_GAD
Epithelial ovarian cancer 0.002638474 2 0 BeFree_GAD
Uterine Fibroids 0.002442977 9 7 BeFree
Anxiety 0.002367032 1 0 GAD
Arthralgia 0.002367032 1 0 GAD
Neoplastic Cell Transformation 0.002367032 1 0 GAD
Constipation 0.002367032 1 0 GAD
Crohn Disease 0.002367032 1 0 GAD
DNA Damage 0.002367032 1 0 GAD
Endocrine System Diseases 0.002367032 1 0 GAD
Gastrointestinal Diseases 0.002367032 1 0 GAD
Female Genital Diseases 0.002367032 1 0 GAD
Gout 0.002367032 1 0 GAD
Hyperalgesia 0.002367032 1 0 GAD
Kidney Neoplasm 0.002367032 1 0 GAD
Chronic Obstructive Airway Disease 0.002367032 1 0 GAD
Malignant Carcinoid Syndrome 0.002367032 1 0 GAD
Mesothelioma 0.002367032 1 0 GAD
Metaplasia 0.002367032 1 0 GAD
Movement Disorders 0.002367032 1 0 GAD
Musculoskeletal Diseases 0.002367032 1 0 GAD
Opioid-Related Disorders 0.002367032 1 0 GAD
Nausea 0.002367032 1 0 GAD
Occupational Diseases 0.002367032 1 0 GAD
Ocular Motility Disorders 0.002367032 1 0 GAD
Osteoarthritis of hip 0.002367032 1 0 GAD
Pain, Intractable 0.002367032 1 0 GAD
Pleural Neoplasms 0.002367032 1 0 GAD
Pregnancy Complications 0.002367032 1 0 GAD
Restless Legs Syndrome 0.002367032 1 0 GAD
Shock 0.002367032 1 0 GAD
Speech Disorders 0.002367032 1 0 GAD
Stomach Neoplasms 0.002367032 1 0 GAD
Thyroid Neoplasm 0.002367032 1 0 GAD
Bronchial Hyperreactivity 0.002367032 1 0 GAD
Migraine with Aura 0.002367032 1 0 GAD
Amyloid Neuropathies, Familial 0.002367032 1 0 GAD
Leiomyomatosis 0.002367032 1 0 GAD
Medullary carcinoma 0.002367032 1 0 GAD
Oxidative Stress 0.002367032 1 0 GAD
Physical aggression 0.002367032 1 0 GAD
Response to pain finding 0.002367032 1 0 GAD
Dyslexia 0.002367032 1 0 GAD
Premenstrual Dysphoric Disorder 0.002367032 1 0 GAD
Postoperative Nausea and Vomiting 0.002367032 1 0 GAD
Malignant neoplasm of esophagus 0.002367032 1 0 GAD
Hyperhomocysteinemia 0.002367032 1 0 GAD
Vasospasm, Intracranial 0.002367032 1 0 GAD
Sleep Disorders 0.002367032 1 0 GAD
Genomic Instability 0.002367032 1 0 GAD
Acute Coronary Syndrome 0.002367032 1 0 GAD
Testicular Germ Cell Tumor 0.002367032 1 0 GAD
Cirrhosis 0.002367032 1 0 GAD
Maduromycosis 0.002367032 1 0 GAD
Weight Loss Adverse Event 0.002367032 1 0 GAD
Borderline Personality Disorder 0.002171535 8 2 BeFree
Nicotine Dependence 0.002171535 8 1 BeFree
Chronic pain 0.002171535 8 2 BeFree
Malignant neoplasm of endometrium 0.001900093 7 1 BeFree
Uterine Corpus Cancer 0.001900093 7 1 BeFree
Bronchopulmonary Dysplasia 0.001628651 6 1 BeFree
Presenile dementia 0.001628651 6 0 BeFree
Violence 0.001628651 6 1 BeFree
Tardive Dyskinesia 0.001628651 6 1 BeFree
Affective Disorders, Psychotic 0.001357209 5 1 BeFree
Drug abuse 0.001357209 5 0 BeFree
Irritable Bowel Syndrome 0.001357209 5 1 BeFree
nervous system disorder 0.001357209 5 2 BeFree
Post-Traumatic Stress Disorder 0.001357209 5 1 BeFree
Temporomandibular Joint Dysfunction Syndrome 0.001357209 5 1 BeFree
Chronic schizophrenia 0.001357209 5 1 BeFree
Memory impairment 0.001357209 5 1 BeFree
Absence of pain sensation 0.001357209 5 0 BeFree
Autism Spectrum Disorders 0.001357209 5 2 BeFree
TIBIAL MUSCULAR DYSTROPHY, TARDIVE 0.001357209 5 1 BeFree
Atrial Septal Defects 0.001085767 4 1 BeFree
Schizoaffective Disorder 0.001085767 4 0 BeFree
Conduct Disorder 0.001085767 4 1 BeFree
Drug usage 0.001085767 4 1 BeFree
Manic 0.001085767 4 1 BeFree
Mixed anxiety and depressive disorder 0.001085767 4 1 BeFree
Ichthyosis Bullosa of Siemens 0.001085767 4 1 BeFree
Cancer pain 0.001085767 4 1 BeFree
Substance abuse problem 0.001085767 4 0 BeFree
Bipolar I disorder 0.001085767 4 0 BeFree
Malignant tumor of colon 0.000814326 3 1 BeFree
Female Breast Carcinoma 0.000814326 3 1 BeFree
Delusions 0.000814326 3 2 BeFree
Ovarian Carcinoma 0.000814326 3 1 BeFree
Hearing Loss, Mixed Conductive-Sensorineural 0.000814326 3 0 BeFree
Psychiatric symptom 0.000814326 3 0 BeFree
Malignant neoplasm of female breast 0.000814326 3 1 BeFree
Bipolar II disorder 0.000814326 3 0 BeFree
Pain Disorder 0.000814326 3 0 BeFree
Metabolic Syndrome X 0.000814326 3 0 BeFree
Carcinoma of lung 0.000814326 3 1 BeFree
Colon Carcinoma 0.000814326 3 1 BeFree
Carcinoma of bladder 0.000814326 3 0 BeFree
homicidal 0.000814326 3 2 BeFree
Acute postoperative pain 0.000814326 3 0 BeFree
Bulimia Nervosa 0.000814326 3 1 BeFree
Arteriosclerosis 0.000542884 2 0 BeFree
Non-Small Cell Lung Carcinoma 0.000542884 2 4 BeFree
Colorectal Carcinoma 0.000542884 2 0 BeFree
Coronary Arteriosclerosis 0.000542884 2 2 BeFree
Coronary heart disease 0.000542884 2 1 BeFree
Eclampsia 0.000542884 2 1 BeFree
Fatigue 0.000542884 2 1 BeFree
Neuralgia 0.000542884 2 0 BeFree
Polycystic Ovary Syndrome 0.000542884 2 0 BeFree
Stress, Psychological 0.000542884 2 0 BeFree
Substance Use Disorders 0.000542884 2 0 BeFree
Tobacco Dependence 0.000542884 2 0 BeFree
Spina Bifida 0.000542884 2 1 BeFree
Apathy 0.000542884 2 1 BeFree
Dysphoric mood 0.000542884 2 3 BeFree
Extrapyramidal sign 0.000542884 2 0 BeFree
Generalized Anxiety Disorder 0.000542884 2 0 BeFree
Endometriosis of uterus 0.000542884 2 0 BeFree
Abnormal involuntary movement 0.000542884 2 1 BeFree
Inattention 0.000542884 2 0 BeFree
Opiate Addiction 0.000542884 2 2 BeFree
Cocaine Dependence 0.000542884 2 1 BeFree
Premenopausal breast cancer 0.000542884 2 2 BeFree
manic symptom 0.000542884 2 0 BeFree
Schizophrenia and related disorders 0.000542884 2 0 BeFree
Invasive breast carcinoma 0.000542884 2 0 BeFree
Impulsive aggression 0.000542884 2 1 BeFree
Mild cognitive disorder 0.000542884 2 1 BeFree
Generalized vitiligo 0.000542884 2 0 BeFree
Cognitive changes 0.000542884 2 3 BeFree
Paranoia 0.000542884 2 0 BeFree
VITILIGO-ASSOCIATED MULTIPLE AUTOIMMUNE DISEASE SUSCEPTIBILITY 1 (finding) 0.000542884 2 0 BeFree
Alcohol Withdrawal Delirium 0.000271442 1 0 BeFree
Anaplasia 0.000271442 1 0 BeFree
Anemia, Sickle Cell 0.000271442 1 2 BeFree
Anorexia 0.000271442 1 0 BeFree
Behavior Disorders 0.000271442 1 0 BeFree
Depression, Bipolar 0.000271442 1 0 BeFree
Cannabis Abuse 0.000271442 1 0 BeFree
Rectal Carcinoma 0.000271442 1 0 BeFree
Squamous cell carcinoma 0.000271442 1 2 BeFree
Carpal Tunnel Syndrome 0.000271442 1 1 BeFree
Neck Pain 0.000271442 1 0 BeFree
Endogenous depression 0.000271442 1 0 BeFree
Disruptive Behavior Disorder 0.000271442 1 0 BeFree
Dizziness 0.000271442 1 0 BeFree
Endometrial Hyperplasia 0.000271442 1 3 BeFree
Epilepsy 0.000271442 1 3 BeFree
Breast Fibrocystic Disease 0.000271442 1 0 BeFree
Flushing 0.000271442 1 3 BeFree
Hepatitis C 0.000271442 1 0 BeFree
Disruptive, Impulse Control, and Conduct Disorders 0.000271442 1 0 BeFree
Liver diseases 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Lymphoma, Follicular 0.000271442 1 1 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Dental Fluorosis, Acquired 0.000271442 1 0 BeFree
Narcissism 0.000271442 1 0 BeFree
Nausea and vomiting 0.000271442 1 0 BeFree
Neonatal Abstinence Syndrome 0.000271442 1 0 BeFree
Neurotic Disorders 0.000271442 1 0 BeFree
Ovarian Diseases 0.000271442 1 0 BeFree
Pituitary Diseases 0.000271442 1 0 BeFree
Psychoses, Drug 0.000271442 1 1 BeFree
Paranoid Schizophrenia 0.000271442 1 0 BeFree
Schizophreniform Disorders 0.000271442 1 0 BeFree
Sciatica 0.000271442 1 1 BeFree
Stereotyped Behavior 0.000271442 1 0 BeFree
Vertigo 0.000271442 1 0 BeFree
Seasonal Affective Disorder 0.000271442 1 0 BeFree
Polydipsia 0.000271442 1 0 BeFree
Depressive Syndrome 0.000271442 1 0 BeFree
somatization 0.000271442 1 0 BeFree
Central nervous system depression (disorder) 0.000271442 1 0 BeFree
Drug withdrawal syndrome 0.000271442 1 1 BeFree
Disorder of endocrine ovary 0.000271442 1 0 BeFree
Acute onset pain 0.000271442 1 2 BeFree
Kleine-Levin Syndrome 0.000271442 1 0 BeFree
childhood brain tumor 0.000271442 1 0 BeFree
Myalgia 0.000271442 1 0 BeFree
Catch - Finding of sensory dimension of pain 0.000271442 1 1 BeFree
Psychological symptom 0.000271442 1 0 BeFree
Emotional disorder 0.000271442 1 1 BeFree
Free-floating anxiety 0.000271442 1 0 BeFree
Mechanical pain 0.000271442 1 1 BeFree
Pancreatic carcinoma 0.000271442 1 0 BeFree
Alcohol withdrawal syndrome 0.000271442 1 0 BeFree
Alcohol or Other Drugs use 0.000271442 1 0 BeFree
Desquamative interstitial pneumonia 0.000271442 1 1 BeFree
Selenium deficiency 0.000271442 1 0 BeFree
Prodrome 0.000271442 1 0 BeFree
anxiety generalized 0.000271442 1 0 BeFree
Impaired glucose tolerance 0.000271442 1 0 BeFree
Malignant Childhood Neoplasm 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Squamous cell carcinoma of esophagus 0.000271442 1 0 BeFree
Prolapsed lumbar disc 0.000271442 1 1 BeFree
Sexual abuse 0.000271442 1 1 BeFree
Obesity, Abdominal 0.000271442 1 1 BeFree
Malignant neoplasm of pancreas 0.000271442 1 0 BeFree
Chronic tension-type headache 0.000271442 1 1 BeFree
Chronic low back pain 0.000271442 1 0 BeFree
Respiratory distress 0.000271442 1 0 BeFree
Neurodegenerative Disorders 0.000271442 1 0 BeFree
Aggressive personality 0.000271442 1 1 BeFree
Secondary malignant neoplasm of lymph node 0.000271442 1 0 BeFree
Excessive daytime somnolence 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Anxiety state 0.000271442 1 1 BeFree
Malignant neoplasm of kidney 0.000271442 1 0 BeFree
Ovarian failure 0.000271442 1 0 BeFree
Narcolepsy-Cataplexy Syndrome 0.000271442 1 0 BeFree
Chronic Daily Headache 0.000271442 1 0 BeFree
psychological distress 0.000271442 1 0 BeFree
perfectionism 0.000271442 1 0 BeFree
Carcinogenicity 0.000271442 1 0 BeFree
social stress 0.000271442 1 0 BeFree
Treatment related secondary malignancy 0.000271442 1 0 BeFree
Ischemic stroke 0.000271442 1 0 BeFree
Chronic pain syndrome 0.000271442 1 0 BeFree
Chronic Cancer Pain 0.000271442 1 1 BeFree
Hereditary Nonpolyposis Colorectal Cancer 0.000271442 1 0 BeFree
Sporadic Breast Carcinoma 0.000271442 1 0 BeFree
Renal carcinoma 0.000271442 1 0 BeFree
Attention deficit-hyperactivity 0.000271442 1 1 BeFree
Ovarian Insufficiency 0.000271442 1 0 BeFree
Xenograft Model 0.000271442 1 0 BeFree
Benign Prostatic Hyperplasia 0.000271442 1 0 BeFree
COGNITIVE FUNCTION 1, SOCIAL 0.000271442 1 0 BeFree
Coronary Artery Disease 0.000271442 1 1 BeFree
Stimulant dependence 0.000271442 1 0 BeFree
Executive dysfunction 0.000271442 1 0 BeFree
headache severe 0.000271442 1 0 BeFree
Nociceptive Pain 0.000271442 1 0 BeFree
Ischemic Cerebrovascular Accident 0.000271442 1 0 BeFree
dowling-degos disease 0.000271442 1 0 BeFree
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