COL1A1(collagen, type I, alpha 1) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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17q21.33
基因染色体位置图

This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. [provided by R. Dalgleish, Feb 2008]

[中文简述(自动翻译):]  该基??因编码类型的亲ALPHA1链I型胶原蛋白的三螺旋结构包括两个ALPHA1链和一个α2链。 I型在大多数结缔组织发现原纤维形成的胶原蛋白,并在骨,角膜,真皮和肌腱丰富。在这个基因的突变与成骨不全症类型I-IV,埃勒斯 - 当洛综合征型VIIA,埃勒斯 - 当洛综合征古典型,卡菲病和特发性骨质疏松症。染色体17和22,其中,该基因与该基因对血小板衍生的生长因子β位于之间的相互易位,与称为隆突性皮肤皮肤肿瘤的特定类型,从生长因子的未经调节的表达产生的相关联。两个转录,从使用备用聚腺苷酸化信号的产生,已经确定了该基因。 [由R.达格利什,2008年2月提供]

COL1A1基因的碱基序列:[NCBI]
COL1A1基因的碱基突变:           显示全部snp
rs10144       rs10407       rs867184       rs909102       rs1007085       rs1007086       rs1057297       rs1059454       rs1059475       rs1061237       rs1061947       rs1061970       rs1062135       rs1064882       rs1107946       rs1135348       rs1800012       rs1800211       rs1800212       rs1800214       rs1800215       rs1800217       rs1800218       rs1800219       rs1800220       rs1800695       rs2075554       rs2075555       rs2075556       rs2075557       rs2075558       rs2075559       rs2141279       rs2249492       rs2253369       rs2256835       rs2269336      
rs2277633       rs2277634       rs2586486       rs2586488       rs2586489       rs2586490       rs2586491       rs2586492       rs2586494       rs2586495       rs2586497       rs2586498       rs2696244       rs2696245       rs2696246       rs2696247       rs2696249       rs2696250       rs2696252       rs2696255       rs2696258       rs2734272       rs2734274       rs2734276       rs2734278       rs2734281       rs2857395       rs2857396       rs2857397       rs3062009       rs3205325       rs3205509       rs5820805       rs8075308       rs8076979       rs8179178       rs9898186       rs9913817       rs10680871       rs11079898       rs11327935       rs11556513       rs11657761       rs12603724       rs12937105       rs12944834       rs12949681       rs16948765       rs16948767       rs17639446       rs17853657       rs17857117       rs28403607       rs28574643       rs34940368       rs35017779       rs35183627       rs35231764       rs35626114       rs41316648       rs41316649       rs41316651       rs41316653       rs41316655       rs41316657       rs41316659       rs41316661       rs41316663       rs41316665       rs41316667       rs41316669       rs41316671       rs41316673       rs41316675       rs41316677       rs41316679       rs41316681       rs41316683       rs41316685       rs41316687       rs41316689       rs41316691       rs41316693       rs41316695       rs41316697       rs41316699       rs41316701       rs41316703       rs41316705       rs41316707       rs41316709       rs41316711       rs41316713       rs41316715       rs41316717       rs41316719       rs41316721       rs41316723       rs41316725       rs41317345       rs41317347       rs41317349       rs41317351       rs41317353       rs41317355       rs41317357       rs41317359       rs41317361       rs41317363       rs41317365       rs59595116       rs62062995       rs62062998       rs62637627       rs66592376       rs66664580       rs67771061       rs67891210       rs71379394       rs72645341       rs72645362       rs72645366       rs72648321       rs72648327       rs72648335       rs72651614       rs72651623       rs72651662       rs72651668       rs72653147       rs72653170       rs72653177       rs72654799       rs72656307       rs72656314       rs72656330       rs72656344       rs72667007       rs72667014       rs72667032       rs72826508       rs73338526       rs73338527       rs73987442       rs73987444       rs73987445       rs73987447       rs73987448       rs73987449       rs73987451       rs74375876       rs74790737       rs75168103       rs75329794       rs75456035       rs75713851       rs76055698       rs76133134       rs77192602       rs77448028       rs77837617       rs78114864       rs78271486       rs78377092       rs78805959       rs78912754       rs79061218       rs79480112       rs79768153       rs111375168       rs111435223       rs111539460       rs111549032       rs111652266       rs111738740       rs111953130       rs112018864       rs112042777       rs112139106       rs112143390       rs112274185       rs112502723       rs112626388       rs112674044       rs112681996       rs112781630       rs112830882       rs112866636       rs112873723       rs112938445       rs113437353       rs113506551       rs113638816       rs113647555       rs113648997       rs113676543       rs113769289       rs113858765       rs113950465       rs113984451       rs114028749       rs114896036       rs115997082       rs116464938       rs116794104       rs116854206       rs117580814       rs117672175       rs117746137       rs117884012       rs137937544       rs137987935       rs138078016       rs138164489       rs138542981       rs138544681       rs138557594       rs138570309       rs138693721       rs138749826       rs139202938       rs139289956       rs139388334       rs139593707       rs139673121       rs139840296       rs139955975       rs139996062       rs140222966       rs140295356       rs140619158       rs141011435       rs141077341       rs141117382       rs141219921       rs141411256       rs141726413       rs141792780       rs141800676       rs141805075       rs141888902       rs141910281       rs142101140       rs142128554       rs142312753       rs142554672       rs142570406       rs143049736       rs143123647       rs143365102       rs143980299       rs143997627       rs144024364       rs144060079       rs144134990       rs144751329       rs144820445       rs144889918       rs144911083       rs144950974       rs145008436       rs145188105       rs145251615       rs145307365       rs145446512       rs145608939       rs146016027       rs146035171       rs146247759       rs146431113       rs146450504       rs146693714       rs146713501       rs146777183       rs146899953       rs147104425       rs147266928       rs147277057       rs147447144       rs147462383       rs147483404       rs147743501       rs147936946       rs147938547       rs148110802       rs148131473       rs148216434       rs148275339       rs148596229       rs148639363       rs148659814       rs148737409       rs149027707       rs149295671       rs149301001       rs149352055       rs149419718       rs149561221       rs149820303       rs149949620       rs149980662       rs150038058       rs150193972       rs150479182       rs150535628       rs150723662       rs150751153       rs150803124       rs150854949       rs151114560       rs151171179       rs151328660       rs180689720       rs181206340       rs181453083       rs181712806       rs181824088       rs182179260       rs182302582       rs182400101       rs182439092       rs183016093       rs183617064       rs184193874       rs184600748       rs184720839       rs185277813       rs185305718       rs185786597       rs186025135       rs186249644       rs186558677       rs186835598       rs187079088       rs187265814       rs187653146       rs188681859       rs188733739       rs188887858       rs188965488       rs189542584       rs189707724       rs189745984       rs190098788       rs190510366       rs190512816       rs191053268       rs191166865       rs191326459       rs191598361       rs191715075       rs192054020       rs192202103       rs192268642       rs192986202       rs193922142       rs193922146       rs193922147       rs193922150       rs193922153       rs193922157       rs199507352       rs199510546       rs199514372       rs199521040       rs199523510       rs199626372       rs199631268       rs199766533       rs199769922       rs199771196       rs199783930       rs199805116       rs199806909       rs199854359       rs199891984       rs199911681       rs200011356       rs200063235       rs200106397       rs200111312       rs200142836       rs200145743       rs200164061       rs200178548       rs200188855       rs200319927       rs200352916       rs200355573       rs200458986       rs200467035       rs200520345       rs200551243       rs200564850       rs200574236       rs200581751       rs200620805       rs200621584       rs200689194       rs200720904       rs200750214       rs200778332       rs200786825       rs200786916       rs200794696       rs200821764       rs200834452       rs200990242       rs201066018       rs201070506       rs201085309       rs201091992       rs201118922       rs201122145       rs201136122       rs201181751       rs201222225       rs201227525       rs201236489       rs201256042       rs201291754       rs201349683       rs201354284       rs201398339       rs201412286       rs201448042       rs201450194       rs201591060       rs201606377       rs201627277       rs201679090       rs201682029       rs201746814       rs201916066       rs201920224       rs201920416       rs201925597       rs201934185       rs201953078       rs201994508       rs202019703       rs202122731       rs202131429       rs202170631       rs202179644       rs202185116       rs202221716       rs202224757       rs267604945       rs367630028       rs367637889       rs367643097       rs367662814       rs367663062       rs367802613       rs367826601       rs367861935       rs367886572       rs367939054       rs367952133       rs367971695       rs368008545       rs368234374       rs368237164       rs368246367       rs368259454       rs368295399       rs368316440       rs368351593       rs368378722       rs368379643       rs368380161       rs368476268       rs368570063       rs368669396       rs368700070       rs368746726       rs368754268       rs368775573       rs368826593       rs368832341       rs369006429       rs369016337       rs369076517       rs369077144       rs369093767       rs369126752       rs369138260       rs369209824       rs369226518       rs369247111       rs369249923       rs369283493       rs369422507       rs369426606       rs369436657       rs369449685       rs369455732       rs369473898       rs369507802       rs369626321       rs369670483       rs369676301       rs369694934       rs369699409       rs369898579       rs369925208       rs369971149       rs370308401       rs370310586       rs370384784       rs370390175       rs370394723       rs370410110       rs370459791       rs370529603       rs370547300       rs370564344       rs370574815       rs370865189       rs370895601       rs370916785       rs370984739       rs370986177       rs371006337       rs371161009       rs371219982       rs371229089       rs371234621       rs371264264       rs371277464       rs371312641       rs371324431       rs371449594       rs371547661       rs371697816       rs371705356       rs371715085       rs371817394       rs371904584       rs371961558       rs372008669       rs372017541       rs372029024       rs372034810       rs372035677       rs372159426       rs372169804       rs372204030       rs372215246       rs372250574       rs372290536       rs372319986       rs372336372       rs372353138       rs372452640       rs372631553       rs372658559       rs372726849       rs372799058       rs372943378       rs372949963       rs372961640       rs372981012       rs372996596       rs373003831       rs373036181       rs373041336       rs373097023       rs373169459       rs373386837       rs373450731       rs373474549       rs373496190       rs373528389       rs373611041       rs373624129       rs373689267       rs373725675       rs373728987       rs373777457       rs373802214       rs373830745       rs373873548       rs374065372       rs374094294       rs374095521       rs374149667       rs374158703       rs374165575       rs374268357       rs374278811       rs374322003       rs374375343       rs374424810       rs374465457       rs374582077       rs374592894       rs374615784       rs374625618       rs374783717       rs374789134       rs374849748       rs374853330       rs374861855       rs374909743       rs374947065       rs374990175       rs374996143       rs375006509       rs375248255       rs375347948       rs375517119       rs375529943       rs375531492       rs375561133       rs375650769       rs375695940       rs375696477       rs375823086       rs375865681       rs375914028       rs375939803       rs376024832       rs376047287       rs376087528       rs376098958       rs376179885       rs376223717       rs376260945       rs376316162       rs376390852       rs376449554       rs376524129       rs376546326       rs376569858       rs376614068       rs376700357       rs376722154       rs376752492       rs376783395       rs376795563       rs376886366       rs376904766       rs376928140       rs376935598       rs376952420       rs376981523       rs376986354       rs377076585       rs377113578       rs377117284       rs377123276       rs377161165       rs377195143       rs377263830       rs377327542       rs377367699       rs377400687       rs377415400       rs377457550       rs377678989       rs377682912       rs377698671       rs527358320       rs527505360       rs527624280       rs527856984       rs527895972       rs528056636       rs528349466       rs528805201       rs528872105       rs529004847       rs529107035       rs529255736       rs529415916       rs529873413       rs530196272       rs530354504       rs530547240       rs530988972       rs531312697       rs531350062       rs531476034       rs531558533       rs531890346       rs531952269       rs532172482       rs532232848       rs532373337       rs532554893       rs532741992       rs532923817       rs532961779       rs533106127       rs533127847       rs533165364       rs533416127       rs533960283       rs534288058       rs534369891       rs534405389       rs534473543       rs534488809       rs534528209       rs534706380       rs534823075       rs534976382       rs535236489       rs535566624       rs535579723       rs535610699       rs535613016       rs535736033       rs536196631       rs536312322       rs536652371       rs536806940       rs536939800       rs536973075       rs537060488       rs537139983       rs537224877       rs537589365       rs537980468       rs538068477       rs538187447       rs538224838       rs538343091       rs539049418       rs539228158       rs539456400       rs539689232       rs539738236       rs539778428       rs539791931       rs540027833       rs540190726       rs540488544       rs540596243       rs540637433       rs540756728       rs540794703       rs540822949       rs540903804       rs541301232       rs541387778       rs541492969       rs541912343       rs541971520       rs542133917       rs542174021       rs542355971       rs542486331       rs542615921       rs542721613       rs542766871       rs542979909       rs543160156       rs543172732       rs543185462       rs543333192       rs543348331       rs543571027       rs543701268       rs543735501       rs543780101       rs543809032       rs544344420       rs544409032       rs544574036       rs544610865       rs544760880       rs544922468       rs544994820       rs545033057       rs545378589       rs545518162       rs545843572       rs545946740       rs546009199       rs546069715       rs546112377       rs546269276       rs546629502       rs546697625       rs546881087       rs547392903       rs547744241       rs547759590       rs548004473       rs548048698       rs548069648       rs548254882       rs548470115       rs548928043       rs549195968       rs549319519       rs549697786       rs550053089       rs550265501       rs550290978       rs550291465       rs550354578       rs550433160       rs550861419       rs550898576       rs550900991       rs551247305       rs551499703       rs551536386       rs551706871       rs551796751       rs551886422       rs552043533       rs552047891       rs552087944       rs552379629       rs552450147       rs552851442       rs553014869       rs553014882       rs553051786       rs553175744       rs553233250       rs553267263       rs553852405       rs554031884       rs554217471       rs554392703       rs554507703       rs554507974       rs554858996       rs555018883       rs555557362       rs555687273       rs555722335       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rs766849757       rs766861178       rs766870668       rs766891244       rs766909363       rs766946555       rs767097534       rs767179550       rs767179998       rs767247910       rs767250343       rs767286483       rs767338988       rs767426779       rs767525556       rs767543736       rs767579512       rs767600051       rs767685211       rs767754125       rs767789242       rs767871687       rs767894727       rs767924851       rs767935978       rs767937112       rs767953699       rs767972000       rs768022207       rs768067831       rs768091337       rs768124847       rs768156884       rs768163538       rs768214952       rs768261337       rs768279079       rs768314156       rs768328923       rs768386140       rs768460126       rs768572265       rs768576692       rs768606617       rs768628904       rs768745696       rs768782428       rs768785416       rs768801354       rs768803524       rs768808806       rs768810493       rs768894081       rs768896689       rs768943464       rs768947449       rs769021257       rs769106952       rs769158560       rs769167761       rs769192549       rs769202328       rs769237597       rs769256210       rs769282969       rs769363726       rs769401430       rs769410207       rs769437710       rs769483364       rs769568268       rs769571473       rs769601541       rs769619568       rs769623296       rs769634537       rs769682651       rs769687470       rs769689009       rs769737039       rs769771226       rs769791947       rs769827847       rs769834236       rs769867566       rs769875560       rs769959780       rs769990458       rs770033774       rs770034178       rs770034541       rs770083936       rs770125257       rs770169695       rs770277944       rs770279478       rs770279565       rs770295048       rs770326881       rs770355998       rs770369572       rs770407108       rs770414874       rs770426648       rs770450635       rs770454346       rs770457399       rs770492541       rs770506745       rs770509004       rs770568983       rs770596593       rs770620601       rs770674562       rs770687908       rs770730399       rs770748533       rs770822473       rs770826227       rs770877546       rs770906687       rs770907666       rs770925126       rs770952893       rs770997235       rs771009515       rs771076396       rs771080064       rs771103708       rs771177331       rs771310430       rs771333800       rs771340677       rs771489142       rs771503894       rs771512754       rs771552286       rs771593907       rs771596805       rs771619112       rs771641402       rs771647906       rs771674885       rs771753188       rs771778976       rs771860399       rs771918127       rs771938766       rs771990895       rs772010597       rs772033648       rs772060459       rs772121804       rs772170340       rs772205244       rs772223365       rs772257463       rs772297818       rs772353130       rs772472043       rs772473313       rs772536528       rs772604284       rs772638625       rs772644181       rs772655468       rs772659730       rs772730977       rs772732511       rs772750234       rs772769221       rs772792964       rs772798322       rs772854760       rs772890478       rs772906802       rs772908846       rs772922151       rs772929903       rs772949511       rs772971553       rs773058438       rs773147153       rs773177409       rs773193800       rs773264811       rs773279512       rs773286290       rs773295886       rs773305791       rs773330028       rs773343407       rs773428245       rs773552128       rs773562150       rs773571012       rs773594442       rs773654206       rs773668904       rs773740614       rs773753538       rs773763288       rs773802092       rs773917407       rs773946543       rs773957707       rs773993310       rs774001209       rs774008765       rs774021641       rs774034198       rs774042330       rs774045142       rs774095910       rs774182176       rs774210351       rs774212977       rs774281966       rs774295754       rs774298199       rs774382706       rs774412298       rs774442705       rs774445892       rs774459732       rs774547182       rs774635267       rs774664983       rs774687433       rs774708577       rs774754830       rs774771584       rs774785014       rs774838723       rs775025619       rs775026377       rs775041050       rs775055638       rs775069938       rs775095655       rs775106436       rs775115701       rs775117452       rs775128963       rs775132104       rs775140599       rs775208392       rs775212226       rs775246452       rs775282061       rs775349207       rs775378880       rs775462973       rs775514708       rs775541942       rs775550896       rs775577229       rs775610309       rs775633992       rs775665256       rs775720440       rs775763927       rs775764038       rs775809193       rs775888350       rs775895075       rs775914893       rs775965149       rs775976809       rs775985897       rs775998962       rs776151666       rs776156011       rs776229611       rs776240525       rs776240941       rs776313594       rs776336757       rs776355079       rs776364144       rs776387246       rs776418188       rs776541846       rs776544779       rs776573776       rs776580061       rs776596093       rs776602674       rs776611767       rs776620528       rs776631611       rs776648996       rs776659807       rs776786081       rs776786397       rs776830248       rs776855573       rs776961507       rs777014027       rs777014529       rs777033013       rs777060894       rs777072491       rs777150332       rs777173486       rs777175694       rs777189172       rs777265470       rs777283854       rs777284370       rs777316269       rs777336526       rs777376523       rs777395953       rs777447829       rs777571745       rs777589249       rs777634236       rs777644312       rs777717587       rs777730902       rs777869109       rs777883502       rs777955759       rs777989389       rs778036108       rs778062061       rs778077946       rs778151591       rs778220640       rs778235832       rs778266654       rs778301848       rs778356720       rs778395663       rs778415109       rs778417218       rs778439228       rs778463556       rs778523177       rs778627822       rs778644341       rs778654271       rs778733293       rs778734618       rs778735744       rs778814970       rs778866846       rs778902601       rs779002822       rs779030403       rs779081896       rs779085174       rs779085451       rs779096006       rs779121150       rs779150342       rs779153248       rs779239471       rs779337831       rs779388180       rs779393629       rs779431236       rs779431392       rs779532711       rs779570039       rs779586218       rs779590911       rs779620095       rs779679661       rs779748851       rs779767483       rs779768325       rs779782138       rs779813816       rs779846520       rs779952705       rs779973284       rs780061488       rs780182943       rs780190493       rs780217716       rs780234027       rs780242725       rs780245431       rs780248845       rs780286127       rs780292455       rs780297962       rs780311548       rs780332639       rs780348912       rs780422688       rs780452624       rs780472683       rs780560514       rs780608934       rs780618538       rs780633753       rs780678795       rs780694801       rs780745594       rs780775891       rs780807961       rs780831066       rs780905804       rs780908692       rs780931952       rs780989411       rs781000537       rs781051294       rs781086475       rs781088369       rs781091217       rs781139112       rs781141299       rs781246479       rs781258296       rs781287389       rs781291565       rs781299924       rs781374109       rs781401626       rs781457915       rs781491172       rs781495963       rs781595724       rs781614679       rs781680401       rs781719159       rs781734891       rs781760900       rs781774588      

COL1A1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTGGAAGAGTGGAGAGTACTG
59
GTCTCCATGTTGCAGAAGAC
59
CTGGAAGAGTGGAGAGTACTG
59
GTCTCCATGTTGCAGAAGAC
59
TGCATGATTGCTAGTCTGG
58
GGAAAGTCACAGCATATTCCA
58
GGAAAGAATGGAGATGATGGG
59
ACTGAAACCTCTGTGTCCC
59
TGACTGGAAGAGTGGAGAG
58
GTCTCCATGTTGCAGAAGAC
59
GGTGACAAGGGTGAAAGTG
59
ACAGGTCTTCTGTACTTACGG
59
TCTTGGTTTGGTTGTCAGG
58
CATCATTTCCACGAGCACC
59
GCTAAAGGTGCCAATGGTG
60
CTGTTACCCTTGGGACCAG
60
GTTCAGCTTTGTGGACCTC
59
ATTGGTGGGATGTCTTCGT
59
CAAGTGTGCCTCTTAGACC
58
TCAGTAGTGACTGCAACCC
59
      尚未收录相关数据

COL1A1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

COL1A1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0001501
P02452(UniProtKB)
IMP
GO:0001501
P02452(UniProtKB)
IMP
GO:0001501
P02452(UniProtKB)
IMP
GO:0001568
P02452(UniProtKB)
IMP
GO:0001649
P02452(UniProtKB)
IEA
GO:0001957
P02452(UniProtKB)
IEA
GO:0001958
P02452(UniProtKB)
IEA
GO:0005201
P02452(UniProtKB)
IEA
GO:0005515
P02452(UniProtKB)
IPI
GO:0005515
P02452(UniProtKB)
IPI
GO:0005515
P02452(UniProtKB)
IPI
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005576
P02452(UniProtKB)
TAS
GO:0005584
P02452(UniProtKB)
IMP
GO:0005584
P02452(UniProtKB)
IMP
GO:0005615
P02452(UniProtKB)
IDA
GO:0005788
P02452(UniProtKB)
TAS
GO:0005788
P02452(UniProtKB)
TAS
GO:0005788
P02452(UniProtKB)
TAS
GO:0005788
P02452(UniProtKB)
TAS
GO:0005788
P02452(UniProtKB)
TAS
GO:0005794
P02452(UniProtKB)
IEA
GO:0007596
P02452(UniProtKB)
TAS
GO:0007601
P02452(UniProtKB)
IMP
GO:0007605
P02452(UniProtKB)
IMP
GO:0010718
P02452(UniProtKB)
IDA
GO:0010812
P02452(UniProtKB)
IEA
GO:0015031
P02452(UniProtKB)
IEA
GO:0030141
P02452(UniProtKB)
IEA
GO:0030168
P02452(UniProtKB)
TAS
GO:0030198
P02452(UniProtKB)
TAS
GO:0030199
P02452(UniProtKB)
IMP
GO:0030199
P02452(UniProtKB)
IMP
GO:0030199
P02452(UniProtKB)
IMP
GO:0030199
P02452(UniProtKB)
IMP
GO:0030335
P02452(UniProtKB)
IDA
GO:0030574
P02452(UniProtKB)
TAS
GO:0031012
P02452(UniProtKB)
IDA
GO:0031960
P02452(UniProtKB)
IEA
GO:0032355
P02452(UniProtKB)
IEA
GO:0032964
P02452(UniProtKB)
IMP
GO:0034504
P02452(UniProtKB)
IDA
GO:0034505
P02452(UniProtKB)
IMP
GO:0042493
P02452(UniProtKB)
IEA
GO:0042542
P02452(UniProtKB)
IEA
GO:0042802
P02452(UniProtKB)
IDA
GO:0043434
P02452(UniProtKB)
IEA
GO:0043589
P02452(UniProtKB)
IMP
GO:0044344
P02452(UniProtKB)
IEA
GO:0044691
P02452(UniProtKB)
IEA
GO:0045893
P02452(UniProtKB)
IDA
GO:0046872
P02452(UniProtKB)
IEA
GO:0048407
P02452(UniProtKB)
IDA
GO:0048706
P02452(UniProtKB)
IMP
GO:0050776
P02452(UniProtKB)
TAS
GO:0050900
P02452(UniProtKB)
TAS
GO:0051591
P02452(UniProtKB)
IEA
GO:0055093
P02452(UniProtKB)
IEA
GO:0060325
P02452(UniProtKB)
IEA
GO:0060346
P02452(UniProtKB)
IEA
GO:0060351
P02452(UniProtKB)
IEA
GO:0070208
P02452(UniProtKB)
IEA
GO:0071230
P02452(UniProtKB)
IEA
GO:0071260
P02452(UniProtKB)
IEA
GO:0071260
P02452(UniProtKB)
IEA
GO:0071300
P02452(UniProtKB)
IEA
GO:0071306
P02452(UniProtKB)
IEA
GO:0071356
P02452(UniProtKB)
IEA
GO:0071364
P02452(UniProtKB)
IEA
GO:0071560
P02452(UniProtKB)
IEA
GO:0090263
P02452(UniProtKB)
IDA
GO:1902618
P02452(UniProtKB)
IEA
GO:0031012
P02452(UniProtKB)
IDA
GO:0031012
P02452(UniProtKB)
ISS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控COL1A1基因的相关microRNA:      显示全部miRNA


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Osteogenesis imperfecta type III (disorder) 0.562442977 22 9 BeFree_CLINVAR_CTD_human_MGD_ORPHANET_UNIPROT
Cortical Congenital Hyperostosis 0.484353001 6 1 BeFree_CLINVAR_CTD_human_LHGDN_ORPHANET_UNIPROT
Osteogenesis imperfecta type IV (disorder) 0.481900093 17 3 BeFree_CLINVAR_CTD_human_ORPHANET_UNIPROT
Ehlers-Danlos syndrome type 1 0.480271442 2 1 BeFree_CLINVAR_CTD_human_ORPHANET_UNIPROT
Lobstein's Disease 0.327871814 40 9 BeFree_CLINVAR_MGD_UNIPROT
Osteogenesis imperfecta, dominant perinatal lethal 0.322171535 36 1 BeFree_CTD_human_MGD_UNIPROT
Osteogenesis Imperfecta 0.315633557 130 29 BeFree_CLINVAR_CTD_human_GAD_LHGDN
EHLERS-DANLOS SYNDROME, ARTHROCHALASIA TYPE 0.24 0 0 CTD_human_ORPHANET
Osteoporosis 0.190496532 38 0 BeFree_CTD_human_GAD_LHGDN
Dermatofibrosarcoma Protuberans 0.130857675 40 0 BeFree_ORPHANET
Malignant neoplasm of breast 0.122909916 3 17 BeFree_GAD_GWASCAT
Liver Cirrhosis 0.122638474 4 0 BeFree_CTD_human_GAD
Oral Submucous Fibrosis 0.122367032 2 0 CTD_human_GAD
Spontaneous abortion 0.12 1 0 CTD_human
Aneurysm, Dissecting 0.12 1 0 CTD_human
Aortic Valve Insufficiency 0.12 1 0 CTD_human
Calcinosis 0.12 1 0 CTD_human
Fibrosis 0.12 1 0 CTD_human
Heart valve disease 0.12 1 0 CTD_human
Hypertensive disease 0.12 1 0 CTD_human
Keloid 0.12 1 0 CTD_human
Nephrotic Syndrome 0.12 1 0 CTD_human
Left Ventricular Hypertrophy 0.12 1 0 CTD_human
Osteogenesis imperfecta, recessive perinatal lethal 0.12 0 26 CLINVAR
Nephrogenic Fibrosing Dermopathy 0.12 1 0 CTD_human
OI/EDS Combined Syndrome 0.12 0 1 CLINVAR
Non-alcoholic Fatty Liver Disease 0.080542884 3 0 BeFree_RGD
Arteriovenous fistula 0.08 1 0 RGD
Bladder neck obstruction 0.08 1 0 RGD
Cholestasis 0.08 2 0 RGD
Diabetic Nephropathy 0.08 1 0 RGD
Biliary cirrhosis 0.08 1 0 RGD
Liver Cirrhosis, Experimental 0.08 4 0 RGD
Liver neoplasms 0.08 1 0 RGD
Pulmonary Fibrosis 0.08 1 0 RGD
Ureteral obstruction 0.08 1 0 RGD
Pancreatitis, Chronic 0.08 1 0 RGD
hypertensive nephropathy 0.08 1 0 RGD
Osteoporosis, Postmenopausal 0.024484645 13 0 BeFree_GAD
Otosclerosis 0.013440067 12 0 BeFree_GAD_LHGDN
Ehlers-Danlos Syndrome 0.011158911 14 0 BeFree_LHGDN
Myopia 0.010011012 4 0 BeFree_GAD
beta Thalassemia 0.009825446 3 0 GAD_LHGDN
Uterine Prolapse 0.009468128 4 0 GAD
Premature Birth 0.009468128 4 0 GAD
Degenerative polyarthritis 0.009087065 9 0 BeFree_GAD_LHGDN
Dermatofibrosarcoma 0.008444493 4 0 BeFree_LHGDN
Systemic Scleroderma 0.008434561 12 0 BeFree_LHGDN
Multiple Myeloma 0.008173051 3 0 LHGDN
Pathological fracture 0.007101096 3 0 GAD
Mammary Neoplasms 0.0054487 2 0 LHGDN
Bone Diseases 0.005091382 2 0 GAD_LHGDN
Congenital clubfoot 0.005091382 1 0 GAD_LHGDN
Urinary Incontinence 0.005091382 1 0 GAD_LHGDN
Metabolic Bone Disorder 0.004734064 2 0 GAD
Inflammation 0.004734064 2 0 GAD
Periodontitis 0.004734064 2 0 GAD
Pre-Eclampsia 0.004734064 2 0 GAD
Osteosarcoma 0.002995792 2 0 BeFree_LHGDN
Sarcoma 0.002995792 2 0 BeFree_LHGDN
Hip Dislocation, Congenital 0.002909916 3 0 BeFree_GAD
Arthritis, Psoriatic 0.00272435 1 0 LHGDN
Asthma 0.00272435 1 0 LHGDN
Dental Calculus 0.00272435 1 0 LHGDN
Arthropathy 0.00272435 1 0 LHGDN
Fibroid Tumor 0.00272435 1 0 LHGDN
Chronic Obstructive Airway Disease 0.00272435 1 0 LHGDN
Sarcoidosis 0.00272435 1 0 LHGDN
Syringomyelia 0.00272435 1 0 LHGDN
Epidermolysis Bullosa Dystrophica 0.00272435 1 0 LHGDN
Idiopathic Pulmonary Fibrosis 0.00272435 1 0 LHGDN
Connective Tissue Diseases 0.002638474 2 0 BeFree_GAD
Myocardial Infarction 0.002638474 1 0 BeFree_GAD
Lumbar disc disease 0.002638474 1 0 BeFree_GAD
Achondroplasia 0.002367032 1 0 GAD
Alcoholic Intoxication, Chronic 0.002367032 1 0 GAD
Alzheimer's Disease 0.002367032 1 0 GAD
Uterine Cervical Incompetence 0.002367032 1 0 GAD
Chorioamnionitis 0.002367032 1 0 GAD
Colles' Fracture 0.002367032 1 0 GAD
Deafness 0.002367032 1 0 GAD
Pituitary dwarfism 0.002367032 1 0 GAD
Fetal Diseases 0.002367032 1 0 GAD
Fetal Membranes, Premature Rupture 0.002367032 1 0 GAD
Hearing Loss, Partial 0.002367032 1 0 GAD
Male infertility 0.002367032 1 0 GAD
Insulin Resistance 0.002367032 1 0 GAD
Intervertebral Disk Displacement 0.002367032 1 0 GAD
Premature Obstetric Labor 0.002367032 1 0 GAD
leukemia 0.002367032 1 0 GAD
Musculoskeletal Diseases 0.002367032 1 0 GAD
Osteoarthritis of hip 0.002367032 1 0 GAD
Osteopenia 0.002367032 1 0 GAD
Pregnancy Complications, Hematologic 0.002367032 1 0 GAD
Dermatologic disorders 0.002367032 1 0 GAD
Thalassemia 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Myopia, Degenerative 0.002367032 1 0 GAD
Malignant Bone Neoplasm 0.002367032 1 0 GAD
Hepatitis B, Chronic 0.002367032 1 0 GAD
hearing impairment 0.002367032 1 0 GAD
Coronary Artery Disease 0.002367032 1 0 GAD
Infection of amniotic sac and membranes, unspecified, unspecified trimester, not applicable or unspecified 0.002367032 1 0 GAD
Aortic Stiffness 0.002367032 1 0 GAD
Infection 0.002367032 1 0 GAD
Hearing Loss 0.002367032 1 0 GAD
Increased susceptibility to fractures 0.001900093 7 0 BeFree
Giant Cell Fibroblastoma 0.001357209 5 0 BeFree
Scleroderma 0.001085767 4 0 BeFree
Severe myopia 0.001085767 4 0 BeFree
Pain 0.000814326 3 0 BeFree
Hearing Loss, Mixed Conductive-Sensorineural 0.000814326 3 0 BeFree
Glaucoma, Primary Open Angle 0.000814326 3 0 BeFree
Eosinophilia-Myalgia Syndrome 0.000542884 2 0 BeFree
Bruck syndrome 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 17 BeFree
Brittle Bone Disorder 0.000542884 2 0 BeFree
Cutaneous Fibrous Histiocytoma 0.000271442 1 0 BeFree
Collagen Diseases 0.000271442 1 0 BeFree
Crohn Disease 0.000271442 1 0 BeFree
Diabetes Mellitus 0.000271442 1 0 BeFree
Diabetes Mellitus, Non-Insulin-Dependent 0.000271442 1 0 BeFree
Fibrosarcoma 0.000271442 1 0 BeFree
Hepatitis B 0.000271442 1 0 BeFree
Leishmaniasis, Cutaneous 0.000271442 1 0 BeFree
Leukemia, Lymphocytic, Acute, L1 0.000271442 1 0 BeFree
Malocclusion 0.000271442 1 0 BeFree
Marfan Syndrome 0.000271442 1 0 BeFree
Nodule 0.000271442 1 0 BeFree
Obesity 0.000271442 1 0 BeFree
Oral Manifestations 0.000271442 1 0 BeFree
Ptosis 0.000271442 1 0 BeFree
Scoliosis, unspecified 0.000271442 1 0 BeFree
Skin Neoplasms 0.000271442 1 0 BeFree
Urinary Stress Incontinence 0.000271442 1 1 BeFree
Foot Ulcer 0.000271442 1 0 BeFree
Idiopathic osteoporosis 0.000271442 1 0 BeFree
Uveal melanoma 0.000271442 1 0 BeFree
Fibrosis, Liver 0.000271442 1 0 BeFree
Sclerosteosis 0.000271442 1 0 BeFree
Ehlers-Danlos Syndrome, Type IV 0.000271442 1 0 BeFree
Lipodermatosclerosis 0.000271442 1 0 BeFree
Idiopathic osteoarthritis 0.000271442 1 0 BeFree
Hereditary Connective Tissue Disorder 0.000271442 1 0 BeFree
Blue sclera 0.000271442 1 0 BeFree
Congenital scoliosis 0.000271442 1 0 BeFree
Osteosarcoma of bone 0.000271442 1 0 BeFree
Acquired scoliosis 0.000271442 1 0 BeFree
Hyperuricemia 0.000271442 1 0 BeFree
Malignant neoplasm of kidney 0.000271442 1 0 BeFree
Diffuse Scleroderma 0.000271442 1 0 BeFree
Epithelioma 0.000271442 1 0 BeFree
Renal carcinoma 0.000271442 1 0 BeFree
Tendinopathy 0.000271442 1 0 BeFree
Conventional Dermatofibrosarcoma Protuberans 0.000271442 1 0 BeFree
CAMPOMELIC DYSPLASIA 0.000271442 1 0 BeFree
Osteogenesis Imperfecta, Type V 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree
Nonalcoholic Steatohepatitis 0.000271442 1 0 BeFree
Metastatic Dermatofibrosarcoma Protuberans 0.000271442 1 0 BeFree
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