CHMP4A(charged multivesicular body protein 4A) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

14q12
基因染色体位置图

基因简述

基因简述

CHMP4A belongs to the chromatin-modifying protein/charged multivesicular body protein (CHMP) family. These proteins are components of ESCRT-III (endosomal sorting complex required for transport III), a complex involved in degradation of surface receptor proteins and formation of endocytic multivesicular bodies (MVBs). Some CHMPs have both nuclear and cytoplasmic/vesicular distributions, and one such CHMP, CHMP1A (MIM 164010), is required for both MVB formation and regulation of cell cycle progression (Tsang et al., 2006 [PubMed 16730941]).[supplied by OMIM, Mar 2008]

[中文简述(自动翻译):]  CHMP4A属于染色质修饰蛋白/被控泡体蛋白（CHMP）的家庭。这些蛋白质是ESCRT-III（运输三需要内体排序复合），涉及表面受体蛋白的降解和地层内吞多泡体（MVBs）的复合物的组成部分。一些CHMPs兼得核和细胞质/水疱分布，和一种这样的CHMP，CHMP1A（MIM 164010），需要为MVB形成和细胞周期进展的调节两者（Tsang等人，2006 [搜索PubMed 16730941]）。[由供给OMIM，2008年3月]

OMIM数据库中对CHMP4A基因的介绍     Wikipedia数据库中对CHMP4A基因的介绍

基因序列

基因序列

CHMP4A基因的碱基序列：[NCBI]

基因突变

基因突变

CHMP4A基因的碱基突变：           显示全部snp
rs2875       rs1242012       rs1242013       rs1242014       rs1242015       rs1997996       rs2295317       rs2295318       rs2295319       rs2295320       rs2295321       rs2295322       rs3215610       rs3783441       rs4597237       rs4982871       rs8006816       rs8007272       rs10136993       rs10144791       rs11428547       rs11629429       rs12436892       rs12589157       rs12886146       rs17101962       rs17693590       rs71119065       rs71119066       rs71119067       rs74037008       rs75958407       rs76057705       rs76444629       rs76856094       rs77308632       rs79864431      
rs111479143       rs112292340       rs112390617       rs112658169       rs113112914       rs113171145       rs113657063       rs113913060       rs113997187       rs114715888       rs117408687       rs117552046       rs138885207       rs138896560       rs138949012       rs139705419       rs140361770       rs140566221       rs141054901       rs141920693       rs141941051       rs141982789       rs142073286       rs143526205       rs143736280       rs143942402       rs143967186       rs144176103       rs144411001       rs144854155       rs145042317       rs145119541       rs145143053       rs145254894       rs145600912       rs145806351       rs146309316       rs146361381       rs146389065       rs146804911       rs146847578       rs147406718       rs147600552       rs148036845       rs148081915       rs148589696       rs148607483       rs148953184       rs149130187       rs149482795       rs149642194       rs149955578       rs151089933       rs151144043       rs181203318       rs182688302       rs182976930       rs184050906       rs184559870       rs186290545       rs187396310       rs187523568       rs188138293       rs189129112       rs189983903       rs190711050       rs190832518       rs191985418       rs193295259       rs199498643       rs199856180       rs200162662       rs200207999       rs200540451       rs200913312       rs201017397       rs201257287       rs201480938       rs201515371       rs201938761       rs201973376       rs367709493       rs367911559       rs368002204       rs368362642       rs368413494       rs368781852       rs368915647       rs369059007       rs369172011       rs369343628       rs370252431       rs370444152       rs370750839       rs370925626       rs370939325       rs371040827       rs371123322       rs371342323       rs371848768       rs371924940       rs371942693       rs372219627       rs372362553       rs372507694       rs372524634       rs372623480       rs372702436       rs373027314       rs373464425       rs373571782       rs373966291       rs374063034       rs374152302       rs374613616       rs374691508       rs374883618       rs375056533       rs375099803       rs375214759       rs375380712       rs375389578       rs375497293       rs376398125       rs377089196       rs377515704       rs377678343       rs377711229       rs398024581       rs527253160       rs527605096       rs527917582       rs529526792       rs529565317       rs531116002       rs531446483       rs532377444       rs533260134       rs533438540       rs533615873       rs534511022       rs535009869       rs536322257       rs536585978       rs537259375       rs537411394       rs537771236       rs538400003       rs538535430       rs538774416       rs539101924       rs540321477       rs540510121       rs541560498       rs542195687       rs542225085       rs543544398       rs543583284       rs543733484       rs544957773       rs545132098       rs545849726       rs546746128       rs547976444       rs548068435       rs548535729       rs548725295       rs551096220       rs553133337       rs553275958       rs555122889       rs555204117       rs555343065       rs555779151       rs555871967       rs556148801       rs556369622       rs556937941       rs557101582       rs557330728       rs557891163       rs557952885       rs558216270       rs558859530       rs558909413       rs559083348       rs559092320       rs560144999       rs560248281       rs560846611       rs561605129       rs562679757       rs562710046       rs562884470       rs563556421       rs563719275       rs564185743       rs564523733       rs565611621       rs565976722       rs566663771       rs566670263       rs566788599       rs567324608       rs567498735       rs567537375       rs568664979       rs569085037       rs569301549       rs569325694       rs570415849       rs571031692       rs571272812       rs571817320       rs571866093       rs572392589       rs572434863       rs572453234       rs573991898       rs574532063       rs575738905       rs575777962       rs576790627       rs576836401       rs577795626       rs578035809       rs745322383       rs745565324       rs745690705       rs745737788       rs745842019       rs745921478       rs745988233       rs746172867       rs746466932       rs746706935       rs746736121       rs746785073       rs746813444       rs747027739       rs747043171       rs747071344       rs747242236       rs747322251       rs747541492       rs747834799       rs747885783       rs747889785       rs747941364       rs748140622       rs748186033       rs748457977       rs748473647       rs748501281       rs748665711       rs748842541       rs748962147       rs749017330       rs749051297       rs749148547       rs749224432       rs749273781       rs749277897       rs749360328       rs749550755       rs749603690       rs749607924       rs749901850       rs750160396       rs750214495       rs750800977       rs750942020       rs751028623       rs751032912       rs751117443       rs751315520       rs751364719       rs751563297       rs751596961       rs751698495       rs751896145       rs751896768       rs751983750       rs752044400       rs752178530       rs752669499       rs752826422       rs753028426       rs753083568       rs753138859       rs753607949       rs753646844       rs753844558       rs753987448       rs754056488       rs754218241       rs754252657       rs754307869       rs754404587       rs754404734       rs754452200       rs754875485       rs754927249       rs754963764       rs755163433       rs755218619       rs755232170       rs755272045       rs755299003       rs755467451       rs755772533       rs755822554       rs756096425       rs756401755       rs756403727       rs756581101       rs756904046       rs756939556       rs756959163       rs757251775       rs757409020       rs757686902       rs757811080       rs757883054       rs757926155       rs758120405       rs758122222       rs758186178       rs758343224       rs758387253       rs758519935       rs758572495       rs758729412       rs758770893       rs758925197       rs758953039       rs759074043       rs759105612       rs759156588       rs759281065       rs759912537       rs760109067       rs760111939       rs760132790       rs760234379       rs760308333       rs760415246       rs760579803       rs760656021       rs761027347       rs761084506       rs761084532       rs761275172       rs761439917       rs761454982       rs761832708       rs761987435       rs762042465       rs762088409       rs762226492       rs762408161       rs762435968       rs762459227       rs762766080       rs762970351       rs763146098       rs763361911       rs763559842       rs763810595       rs764177509       rs764385329       rs764417489       rs764525280       rs764546223       rs764577380       rs764599103       rs764846229       rs765000052       rs765269280       rs765616109       rs765676760       rs765685878       rs765957054       rs766142791       rs766355178       rs766509120       rs766562619       rs766834674       rs766923570       rs767092868       rs767142539       rs767145967       rs767754561       rs767863464       rs767994888       rs768063531       rs768224762       rs768279836       rs768442286       rs768445146       rs768483643       rs768494678       rs768815816       rs768837042       rs768962135       rs769182213       rs769256837       rs769316309       rs769357581       rs769517081       rs769620913       rs769802310       rs770007542       rs770110589       rs770202043       rs770403232       rs770462288       rs770750463       rs770765405       rs770826445       rs770903534       rs771064684       rs771177184       rs771472519       rs771651000       rs771762799       rs771866720       rs771963260       rs772101723       rs772306782       rs772562479       rs772669721       rs772685677       rs772731452       rs772740993       rs772780946       rs772800808       rs773170560       rs773224040       rs773307111       rs773364907       rs773725812       rs773963236       rs774111147       rs774307454       rs774318483       rs774361010       rs774384424       rs774439460       rs774660880       rs775015101       rs775066431       rs775152959       rs775184294       rs775423727       rs775458110       rs775967663       rs776019197       rs776074107       rs776076407       rs776090877       rs776144329       rs776278461       rs776577836       rs776846184       rs776935654       rs777020587       rs777527256       rs777582416       rs777608388       rs777950324       rs778044294       rs778096168       rs778161956       rs778393755       rs778516233       rs778615525       rs778641533       rs778649136       rs778668678       rs778790488       rs779239834       rs779290833       rs779457072       rs779819562       rs779824118       rs779952199       rs780071229       rs780202346       rs780202707       rs780253706       rs780267441       rs780604543       rs780740011       rs780957463       rs781010478       rs781067601       rs781369712       rs781415843       rs781466784       rs869308803      

基因表达

基因表达

CHMP4A基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
ATGCAGAAGTCCTTCGTACC
60
CTACCTTGTCAATGTCCATGTC
59
ATGTGGATGAGGATGAACTG
57
CGCCCACATTTAACAACTC
57
ATGCAGAAGTCCTTCGTACC
60
CTACCTTGTCAATGTCCATGTC
59
AACAGCCAAGAAGTATGGGA
59
GCATTCTCAATGGCCTCAC
59
GAAGTATGGGACCAAGAATAAGAG
59
AATGTCCCGTCAGTTTGTG
58
CAATGCAGAAGTCCTTCGT
58
ACCTTGTCAATGTCCATGTC
58
ATGCAGAAGTCCTTCGTACC
60
CTACCTTGTCAATGTCCATGTC
59
AGGGATCTAAGGGAAGAAGG
58
ATCAGTATCTTCTCTGTCTCCT
58
CAATGCAGAAGTCCTTCGT
58
ACCTTGTCAATGTCCATGTC
58
GGACAACATGGGAAGAAGG
58
GATCAGTATCTTCTCTGTCTCCT
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CHMP4A基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CHMP4A基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0005622
E9PQ80(UniProtKB)
IEA
GO:0007034
E9PQ80(UniProtKB)
IEA
GO:0005622
E9PQI5(UniProtKB)
IEA
GO:0007034
E9PQI5(UniProtKB)
IEA
GO:0005622
H0YI89(UniProtKB)
IEA
GO:0007034
H0YI89(UniProtKB)
IEA
GO:0005622
H0YIN6(UniProtKB)
IEA
GO:0007034
H0YIN6(UniProtKB)
IEA
GO:0000815
Q9BY43(UniProtKB)
TAS
GO:0000815
Q9BY43(UniProtKB)
IDA
GO:0000815
Q9BY43(UniProtKB)
IDA
GO:0000920
Q9BY43(UniProtKB)
IMP
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005515
Q9BY43(UniProtKB)
IPI
GO:0005634
Q9BY43(UniProtKB)
IDA
GO:0005737
Q9BY43(UniProtKB)
IDA
GO:0005737
Q9BY43(UniProtKB)
IDA
GO:0005829
Q9BY43(UniProtKB)
TAS
GO:0005829
Q9BY43(UniProtKB)
TAS
GO:0005829
Q9BY43(UniProtKB)
TAS
GO:0006620
Q9BY43(UniProtKB)
IMP
GO:0006900
Q9BY43(UniProtKB)
IGI
GO:0006900
Q9BY43(UniProtKB)
IMP
GO:0006914
Q9BY43(UniProtKB)
TAS
GO:0006997
Q9BY43(UniProtKB)
IMP
GO:0007080
Q9BY43(UniProtKB)
IMP
GO:0008289
Q9BY43(UniProtKB)
IEA
GO:0009898
Q9BY43(UniProtKB)
IDA
GO:0010324
Q9BY43(UniProtKB)
IMP
GO:0016197
Q9BY43(UniProtKB)
TAS
GO:0019058
Q9BY43(UniProtKB)
TAS
GO:0030117
Q9BY43(UniProtKB)
IMP
GO:0030496
Q9BY43(UniProtKB)
IDA
GO:0030659
Q9BY43(UniProtKB)
IEA
GO:0031902
Q9BY43(UniProtKB)
IEA
GO:0036258
Q9BY43(UniProtKB)
TAS
GO:0039702
Q9BY43(UniProtKB)
TAS
GO:0039702
Q9BY43(UniProtKB)
IGI
GO:0039702
Q9BY43(UniProtKB)
IDA
GO:0042802
Q9BY43(UniProtKB)
IMP
GO:0042803
Q9BY43(UniProtKB)
IPI
GO:0051117
Q9BY43(UniProtKB)
IPI
GO:0051258
Q9BY43(UniProtKB)
IMP
GO:0051260
Q9BY43(UniProtKB)
IMP
GO:0070062
Q9BY43(UniProtKB)
IDA
GO:0097320
Q9BY43(UniProtKB)
IGI
GO:0097320
Q9BY43(UniProtKB)
IMP
GO:1901215
Q9BY43(UniProtKB)
IMP
GO:1902902
Q9BY43(UniProtKB)
IMP
GO:0005768
Q9BY43(UniProtKB)
IDA
GO:0005886
Q9BY43(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CHMP4A基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Cataract 0.000542884 2 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Mumps 0.000271442 1 0 BeFree
Bilateral cataracts (disorder) 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

没有相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2