CGA(glycoprotein hormones, alpha polypeptide)

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

6q14-q21
基因染色体位置图

The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]

[中文简述(自动翻译):]  

CGA基因的碱基序列:[NCBI]
CGA基因的碱基突变:           显示全部snp
rs6155       rs6631       rs932742       rs1055409       rs1983841       rs2011192       rs2025486       rs2031365       rs2031366       rs2242602       rs2274137       rs2274138       rs3828759       rs4706286       rs4706287       rs4986869       rs4986870       rs6924373       rs6924434       rs6926846       rs7738290       rs7739548       rs7740951       rs7741514       rs7745823       rs7751610       rs7759783       rs9342104       rs9344672       rs9344673       rs9344674       rs9344675       rs9351113       rs9444470       rs9444471       rs9444472       rs9986555      
rs11380231       rs11547901       rs12664322       rs13192118       rs16878311       rs34283595       rs35431724       rs35436814       rs36041112       rs57158408       rs57198561       rs58260165       rs58447011       rs59698344       rs71014987       rs71553498       rs71553499       rs71859822       rs73499717       rs73499719       rs73753695       rs73753696       rs73754908       rs73754909       rs73754910       rs73754911       rs74811245       rs75633904       rs77122732       rs77805765       rs77846138       rs78037167       rs78244211       rs78590098       rs79131513       rs79238859       rs79859382       rs111334858       rs111429440       rs111504328       rs111633133       rs112302681       rs112406495       rs112465509       rs113530868       rs113592041       rs113601994       rs114348965       rs114485483       rs114948501       rs115444171       rs115482860       rs115697313       rs116128551       rs116555312       rs117247092       rs117807592       rs138182949       rs138468791       rs138510445       rs138953798       rs139097763       rs139164110       rs139301442       rs139368248       rs139646095       rs139810378       rs140519845       rs140639339       rs141386751       rs142577982       rs142609787       rs142673245       rs142907318       rs143207409       rs143780652       rs143936978       rs144073369       rs144191580       rs144696676       rs144984429       rs145483058       rs145503313       rs145923049       rs146255293       rs146274286       rs146694274       rs147272976       rs147748826       rs147925867       rs148084248       rs148402856       rs148435935       rs149370979       rs149689235       rs149741195       rs150816870       rs180866058       rs181149688       rs181584703       rs181739338       rs182020453       rs182380510       rs182787233       rs182957636       rs183111370       rs183638396       rs184094751       rs184194781       rs184269271       rs184648997       rs184875154       rs184942595       rs185971147       rs185994130       rs186357697       rs186475201       rs186558451       rs186652195       rs187255551       rs187767190       rs188014180       rs188243166       rs188263513       rs189021540       rs189681313       rs189695106       rs190955977       rs191106291       rs191233621       rs191775331       rs192001828       rs192121099       rs192368384       rs192382535       rs192981823       rs200412903       rs200419004       rs201131836       rs201187778       rs202107896       rs202123656       rs367727555       rs368149375       rs368530753       rs368908633       rs369003016       rs370148190       rs371381178       rs372548569       rs373317335       rs373897638       rs375406024       rs376588601       rs376830594       rs397705341       rs397737024       rs398002172       rs527282552       rs527316309       rs527351380       rs528726389       rs528761266       rs529537539       rs529941743       rs529981971       rs530061452       rs530173584       rs530846044       rs531280986       rs531372625       rs532013539       rs532367344       rs532796300       rs532810220       rs533430211       rs533606765       rs533644361       rs534012036       rs534644162       rs535009183       rs535126573       rs535154372       rs535291972       rs535490976       rs536311624       rs536498211       rs536551319       rs537698082       rs537731490       rs537956209       rs538162864       rs538282967       rs538479857       rs538715032       rs538930115       rs538939512       rs539106558       rs539166576       rs539692654       rs539885021       rs540754808       rs540791645       rs540977356       rs541968183       rs542585802       rs542650062       rs542899324       rs543131652       rs543363499       rs544052966       rs544121269       rs544435409       rs544478625       rs544572359       rs544713734       rs546022308       rs547310895       rs547311336       rs547485056       rs547565497       rs548184799       rs548269987       rs548529897       rs548536715       rs548785071       rs548877670       rs549096498       rs549665774       rs549799215       rs549867047       rs550101396       rs551008347       rs551042864       rs551086626       rs551251794       rs552205735       rs552408173       rs552756537       rs552978865       rs553955877       rs554674843       rs554871773       rs555114598       rs555362488       rs555546352       rs556870920       rs557012455       rs557087318       rs557314867       rs557543061       rs558158247       rs558194930       rs558713673       rs559571009       rs560555514       rs560690929       rs562207953       rs562288352       rs562320917       rs562905433       rs563664915       rs563671604       rs563703822       rs564279581       rs564340075       rs564470118       rs564618283       rs564726560       rs565203037       rs565799156       rs565878789       rs565902091       rs567102355       rs567327547       rs567470372       rs567529754       rs568080487       rs568583046       rs568783779       rs568811742       rs568846933       rs569272964       rs569455421       rs570046965       rs570169014       rs570209328       rs571010356       rs571118391       rs571340390       rs571443804       rs571528759       rs571575306       rs571813061       rs572323603       rs572771115       rs572989208       rs573291775       rs573330679       rs573515118       rs574000763       rs575395474       rs575591524       rs576903544       rs577193582       rs577425797       rs577821152       rs745325225       rs745838602       rs746721592       rs746995347       rs747532786       rs747948475       rs748215278       rs748376783       rs749001820       rs749409684       rs749491316       rs750122278       rs750514575       rs750515377       rs750908292       rs752122024       rs752689348       rs753054490       rs753953514       rs755232607       rs756101000       rs756147637       rs757013584       rs757113041       rs757240244       rs757370471       rs757851845       rs758439462       rs758954772       rs760112588       rs760584468       rs761085184       rs761576938       rs762070649       rs762154861       rs762316251       rs763064410       rs763639075       rs764168369       rs764470302       rs765035006       rs765486294       rs766598729       rs766785728       rs767955999       rs767994516       rs768499764       rs768732919       rs769144847       rs769198130       rs769570201       rs769728558       rs769877495       rs771399516       rs771573898       rs771897260       rs773060124       rs773891609       rs774683133       rs774888642       rs775116542       rs775554062       rs775989025       rs777020415       rs777502297       rs777733310       rs778561589       rs779070530       rs779785267       rs780203780       rs781108998       rs781214526       rs781221994       rs781348125       rs781547088      

CGA基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TGCTCTCAAACTCCTGAGC
60
GTGCATTCTGGGCAATCTG
60
CATGTTCTCCATTCCGCTC
59
CCATGCACTGAAGTATTGGG
59
TTCGGATCCACAGTCAACC
60
CTGTAGTAATCCATGGCGC
59
GCTAAATCATATAACAGGGTCACAG
60
AATAACAAGTACTGCAGTGGC
59
ATAACAGGGTCACAGTAATGG
58
TAACAAGTACTGCAGTGGC
58
AATCCCTCTTCGGATCCAC
59
TAGTAATCCATGGCGCTCC
59
ATGTTCTCCATTCCGCTCC
60
CCCATGCACTGAAGTATTGG
59
TTCGGATCCACAGTCAACC
60
TGTAGTAATCCATGGCGCT
59
TTTCTGGTCACATTGTCGG
58
CAATCCTGCACATCAGGAG
58
CCAAATTTGTGATTGCCCAG
58
CCATGCACTGAAGTATTGGG
59
      尚未收录相关数据

CGA基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CGA基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0005179
A0A087WYZ4(UniProtKB)
IEA
GO:0005576
A0A087WYZ4(UniProtKB)
IEA
GO:0005623
A0A087WYZ4(UniProtKB)
IEA
GO:0006590
A0A087WYZ4(UniProtKB)
IEA
GO:0008406
A0A087WYZ4(UniProtKB)
IEA
GO:0030878
A0A087WYZ4(UniProtKB)
IEA
GO:0032275
A0A087WYZ4(UniProtKB)
IEA
GO:0032870
A0A087WYZ4(UniProtKB)
IEA
GO:0046621
A0A087WYZ4(UniProtKB)
IEA
GO:0046884
A0A087WYZ4(UniProtKB)
IEA
GO:0048589
A0A087WYZ4(UniProtKB)
IEA
GO:0005179
A0A0D9SFJ6(UniProtKB)
IEA
GO:0005576
A0A0D9SFJ6(UniProtKB)
IEA
GO:0005179
A0A0D9SGA7(UniProtKB)
IEA
GO:0005576
A0A0D9SGA7(UniProtKB)
IEA
GO:0005179
A0A0R4J2F0(UniProtKB)
IEA
GO:0005576
A0A0R4J2F0(UniProtKB)
IEA
GO:0005179
P01215(UniProtKB)
IMP
GO:0005515
P01215(UniProtKB)
IPI
GO:0005515
P01215(UniProtKB)
IPI
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005576
P01215(UniProtKB)
TAS
GO:0005796
P01215(UniProtKB)
TAS
GO:0007165
P01215(UniProtKB)
TAS
GO:0007267
P01215(UniProtKB)
TAS
GO:0008284
P01215(UniProtKB)
NAS
GO:0016486
P01215(UniProtKB)
TAS
GO:0030335
P01215(UniProtKB)
NAS
GO:0045944
P01215(UniProtKB)
NAS
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控CGA基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Adrenal Gland Diseases 0.12 1 0 CTD_human
Hemiplegia 0.12 1 0 CTD_human
Oligospermia 0.12 1 0 CTD_human
Ovarian Diseases 0.12 1 0 CTD_human
Uterine Diseases 0.12 1 0 CTD_human
Disease Progression 0.12 1 0 CTD_human
Thyroid cancer, follicular 0.12 1 0 CTD_human
Malignant neoplasm of prostate 0.005819831 6 0 BeFree_GAD
Down Syndrome 0.00408156 6 0 BeFree_LHGDN
Malignant neoplasm of breast 0.003995683 7 0 BeFree_GAD
Mammary Neoplasms 0.003810118 5 0 BeFree_LHGDN
Colorectal Neoplasms 0.00272435 1 0 LHGDN
Pregnancy, Tubal 0.00272435 1 0 LHGDN
Malignant neoplasm of urinary bladder 0.002638474 2 0 BeFree_GAD
Malignant neoplasm of lung 0.002638474 2 3 BeFree_GAD
Autistic Disorder 0.002367032 1 0 GAD
Chronic Obstructive Airway Disease 0.002367032 1 0 GAD
Tobacco Use Disorder 0.002367032 1 0 GAD
Breast Carcinoma 0.001628651 6 0 BeFree
Amnesia, Transient Global 0.001085767 4 0 BeFree
Prostate carcinoma 0.001085767 4 0 BeFree
Choriocarcinoma 0.000814326 3 0 BeFree
Adenoma 0.000542884 2 0 BeFree
Adrenal Gland Neoplasms 0.000542884 2 0 BeFree
Nevus 0.000542884 2 0 BeFree
Melanocytic nevus 0.000542884 2 0 BeFree
Ovarian Carcinoma 0.000542884 2 0 BeFree
Pituitary Adenoma 0.000542884 2 0 BeFree
Aortic Aneurysm, Thoracic 0.000542884 2 0 BeFree
Follicular thyroid carcinoma 0.000542884 2 0 BeFree
Endometrial Carcinoma 0.000542884 2 0 BeFree
Benign melanocytic nevus 0.000542884 2 0 BeFree
Benign Prostatic Hyperplasia 0.000542884 2 0 BeFree
AURAL ATRESIA, CONGENITAL 0.000542884 2 0 BeFree
Anemia, Hemolytic 0.000271442 1 0 BeFree
Aortic Aneurysm 0.000271442 1 0 BeFree
Rheumatoid Arthritis 0.000271442 1 0 BeFree
Malignant neoplasm of endometrium 0.000271442 1 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Carcinoma, Papillary 0.000271442 1 0 BeFree
Cardiovascular Diseases 0.000271442 1 0 BeFree
Hemophilia B 0.000271442 1 0 BeFree
Ehlers-Danlos Syndrome 0.000271442 1 0 BeFree
Yolk Sac Tumor 0.000271442 1 0 BeFree
Gynecomastia 0.000271442 1 0 BeFree
Male infertility 0.000271442 1 0 BeFree
Leprosy, Lepromatous 0.000271442 1 0 BeFree
Lesch-Nyhan Syndrome 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Acute Promyelocytic Leukemia 0.000271442 1 0 BeFree
Leukopenia 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Neuroblastoma 0.000271442 1 0 BeFree
Neurofibromatosis 1 0.000271442 1 0 BeFree
Neutropenia 0.000271442 1 0 BeFree
Prostatic Neoplasms 0.000271442 1 0 BeFree
Retinoblastoma 0.000271442 1 0 BeFree
Giant Cell Arteritis 0.000271442 1 0 BeFree
Trisomy 0.000271442 1 0 BeFree
von Willebrand Disease 0.000271442 1 0 BeFree
Ovarian Hyperstimulation Syndrome 0.000271442 1 0 BeFree
Synovial Cyst 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 0 BeFree
Thyroid Gland Follicular Adenoma 0.000271442 1 0 BeFree
Complete trisomy 18 syndrome 0.000271442 1 0 BeFree
Liver Failure, Acute 0.000271442 1 0 BeFree
Agenesis of corpus callosum 0.000271442 1 0 BeFree
Follicular adenoma 0.000271442 1 0 BeFree
Undifferentiated carcinoma 0.000271442 1 0 BeFree
Germ cell tumor 0.000271442 1 0 BeFree
Trophoblastic Tumor, Placental Site 0.000271442 1 0 BeFree
Carcinoma of Male Breast 0.000271442 1 0 BeFree
Gastrointestinal Stromal Tumors 0.000271442 1 0 BeFree
Stickler syndrome (disorder) 0.000271442 1 0 BeFree
Severe hereditary factor VIII deficiency disease 0.000271442 1 0 BeFree
Antithrombin III Deficiency 0.000271442 1 0 BeFree
Endometriosis of uterus 0.000271442 1 0 BeFree
3 beta-Hydroxysteroid dehydrogenase deficiency 0.000271442 1 0 BeFree
pseudohermaphrodite (non-specific) 0.000271442 1 0 BeFree
Activated Protein C Resistance 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 3 BeFree
Carcinoma of bladder 0.000271442 1 0 BeFree
Familial Retinoblastoma 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
hormone related neoplasm/cancer 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Myxoid cyst 0.000271442 1 0 BeFree
Nonseminomatous germ cell tumor 0.000271442 1 0 BeFree
Mediastinal (Thymic) Large B-Cell Lymphoma 0.000271442 1 0 BeFree
Apocrine Gland Carcinoma 0.000271442 1 0 BeFree
Hypoparathyroidism familial isolated 0.000271442 1 0 BeFree
Uterine Corpus Cancer 0.000271442 1 0 BeFree
Epidermolysa bullosa simplex and limb girdle muscular dystrophy 0.000271442 1 0 BeFree
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