CFD基因详情-基因数据库-基因云馆

CFD(complement factor D (adipsin))

基因简称(symbol)

CFD [HGNC] [GeneCards] [NCBI]

基因种类(locus group)

protein-coding gene

同源简称(alias symbol)

ADN

基因家族代码(gene_family_id)

492 [HGNC] [GenScript]

omim代码

134350

entrez码

1675 [Vega]

vega基因码

ensembl基因码

ENSG00000197766 [Ensembl]

基因家族(gene family)

Complement system

refseq数据库代号

NM_001928

更多...

基因种类(locus_type)

gene with protein product

基因名称状态(status)

Approved

location_sortable

19p13.3

同源基因名称(alias name)

基因名称批准使用时间(date_approved_reserved)

1992-10-21T00:00:00Z

基因简称更名时间(date_symbol_changed)

2006-02-10T00:00:00Z

基因名称更名时间(date_name_changed)

2006-02-10T00:00:00Z

更新时间(date_modified)

2015-04-22T00:00:00Z

ucsc码

uc002lqc.3

ena

M84526

ccds数据码

CCDS12046

uniprot数据码

P00746

pubmed代码

1374388

mgd码

MGI:87931

rgd码

RGD:2498

生命科学数据库(lsdb)

CFDbase: Mutation registry for Factor D deficiency (previously known as DFbase)|http://rna.uta.fi/DFbase/|LRG_46|http://www.lrg-sequence.org/LRG/LRG_46

更新时间(date modified)

2015-04-22T00:00:00Z

cosmic

CFD

mirbase

基因曾用简称(prev symbol)

DF|PFD

基因曾用名称(prev name)

D component of complement (adipsin)|properdin factor D

homeodb

cosmic

CFD

snornabase

bioparadigms slc

orphanet

221187

假基因信息(pseudogeneorg)

horde id

merops

S01.191

imgt

iuphar

kznf基因类别

mamit-trnadb

cd

LncRNA数据库

酶代码

中间纤维数据库

收起

19p13.3

The protein encoded by this gene is a member of the trypsin family of peptidases. The encoded protein is a component of the alternative complement pathway best known for its role in humoral suppression of infectious agents. This protein is also a serine protease that is secreted by adipocytes into the bloodstream. Finally, the encoded protein has a high level of expression in fat, suggesting a role for adipose tissue in immune system biology. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):] 由该基因编码的蛋白质是胰蛋白酶家族肽酶的成员。所编码的蛋白质是其在感染剂的体液抑制作用最知名的补体旁路途径的组分。这种蛋白也由脂肪细胞分泌到血液中的丝氨酸蛋白酶。最后，编码的蛋白质具有在脂肪表达水平高，这表明在免疫系统生物学脂肪组织的作用。 [由RefSeq的，2008年7月提供]

OMIM数据库中对CFD基因的介绍 Wikipedia数据库中对CFD基因的介绍

CFD基因的碱基序列：[NCBI]

CFD基因的碱基突变：显示全部snp

rs8953 rs8953 rs10506 rs10506 rs1135146 rs1135146 rs1624707 rs1624707 rs1624783 rs1624783 rs1626564 rs1626564 rs1629038 rs1629038 rs1651897 rs1651897 rs1683561 rs1683561 rs1683562 rs1683562 rs1683563 rs1683563 rs1683564 rs1683564 rs2230216 rs2230216 rs3826945 rs3826945 rs3834645 rs3834645 rs3842427 rs8107095 rs8107095 rs9304953 rs9304953 rs10407668 rs10407668

rs10469327 rs12150957 rs12150957 rs12985692 rs12985692 rs28591229 rs28591229 rs35186399 rs35186399 rs55855648 rs55855648 rs56236063 rs56236063 rs57197777 rs59681293 rs59681293 rs62132300 rs62132300 rs62132301 rs62132301 rs71335275 rs71335275 rs71335276 rs71335276 rs71743169 rs71743169 rs72984024 rs72984024 rs73492555 rs73492555 rs74176357 rs74176357 rs74490515 rs74490515 rs77956610 rs77956610 rs78422012 rs78422012 rs78866371 rs78866371 rs78984618 rs78984618 rs111560995 rs111560995 rs111800430 rs111800430 rs112469647 rs112469647 rs112639467 rs112639467 rs113208478 rs113208478 rs113257297 rs113257297 rs113320292 rs113320292 rs113372839 rs113372839 rs113730361 rs114518487 rs114518487 rs114709522 rs114709522 rs115260417 rs115260417 rs116035956 rs116035956 rs116135466 rs116135466 rs116425485 rs116425485 rs116451501 rs116451501 rs116938070 rs116938070 rs138342648 rs138342648 rs138470231 rs138859256 rs138859256 rs139048452 rs139048452 rs139122457 rs139122457 rs139666945 rs139666945 rs139756616 rs139756616 rs139992067 rs139992067 rs140312924 rs140312924 rs140532505 rs140532505 rs141885392 rs141885392 rs142668981 rs142668981 rs142940924 rs142940924 rs143199006 rs143199006 rs143479761 rs143479761 rs144077943 rs144077943 rs144932643 rs144932643 rs145060143 rs145060143 rs145297122 rs145297122 rs146182779 rs146182779 rs146314090 rs146314090 rs146447185 rs146447185 rs147192616 rs147192616 rs148038950 rs148038950 rs148617871 rs148617871 rs150488724 rs150488724 rs150557105 rs150557105 rs150646348 rs150646348 rs150784046 rs150784046 rs151302019 rs151302019 rs180778801 rs180778801 rs181369145 rs181369145 rs182067009 rs182067009 rs182219847 rs182219847 rs182593675 rs182593675 rs182650401 rs182650401 rs183218514 rs183218514 rs183946107 rs183946107 rs185125554 rs185125554 rs185476946 rs185476946 rs185568925 rs185568925 rs185649590 rs185649590 rs185719755 rs185719755 rs186278129 rs186278129 rs187211507 rs187211507 rs187336311 rs187336311 rs188277685 rs188277685 rs188344668 rs188344668 rs189642145 rs189642145 rs190087201 rs190087201 rs191674545 rs191674545 rs191774823 rs191774823 rs192328667 rs192328667 rs192462031 rs192462031 rs193047313 rs193047313 rs199541702 rs199541702 rs199583783 rs199583783 rs200372790 rs200372790 rs200917507 rs200917507 rs201046554 rs201046554 rs201362518 rs201362518 rs201477386 rs201477386 rs201757567 rs201757567 rs367549537 rs367549537 rs367763802 rs367763802 rs367853218 rs367853218 rs368253378 rs368253378 rs368577538 rs368577538 rs368581009 rs368581009 rs368754028 rs368754028 rs370047005 rs370047005 rs370100594 rs370100594 rs370120478 rs370120478 rs370162906 rs370162906 rs370546435 rs370546435 rs370580178 rs370580178 rs370726124 rs370726124 rs370962604 rs370962604 rs371290415 rs371290415 rs371606125 rs371606125 rs372044601 rs372044601 rs372377545 rs372377545 rs372482606 rs372482606 rs372646121 rs372646121 rs372735615 rs372735615 rs372792553 rs372792553 rs373019471 rs373019471 rs373034607 rs373034607 rs373339878 rs373339878 rs373872274 rs373872274 rs374520010 rs374520010 rs375658157 rs375658157 rs375772213 rs375772213 rs376159080 rs376159080 rs376221139 rs376221139 rs376448914 rs376448914 rs377191884 rs377191884 rs377242441 rs377242441 rs377388343 rs377388343 rs398033671 rs398033671 rs527344705 rs527344705 rs527409009 rs527409009 rs527675939 rs527675939 rs528066304 rs528066304 rs528784814 rs528784814 rs529019501 rs529019501 rs529179395 rs529179395 rs529356003 rs529356003 rs529438075 rs529438075 rs529786628 rs529786628 rs530405469 rs530405469 rs530769718 rs530769718 rs531078732 rs531078732 rs531082030 rs531082030 rs531143963 rs531143963 rs532022083 rs532022083 rs532888646 rs532888646 rs533102756 rs533102756 rs533268669 rs533268669 rs533431266 rs533431266 rs533512166 rs533512166 rs533964533 rs533964533 rs534009743 rs534009743 rs534031942 rs534031942 rs534062264 rs534062264 rs534307551 rs534307551 rs534366910 rs534366910 rs534426815 rs534426815 rs535195741 rs535195741 rs535978800 rs535978800 rs536048362 rs536048362 rs536049294 rs536049294 rs536049624 rs536049624 rs536239117 rs536239117 rs536376045 rs536376045 rs537721072 rs537721072 rs537724685 rs537724685 rs537964407 rs537964407 rs537987164 rs537987164 rs538171883 rs538171883 rs538454384 rs538454384 rs538700489 rs538700489 rs539418053 rs539418053 rs539779993 rs539779993 rs540048758 rs540048758 rs540111895 rs540111895 rs540425316 rs540425316 rs540548193 rs540548193 rs540742081 rs540742081 rs540805610 rs540805610 rs540805746 rs540805746 rs540867033 rs540867033 rs541187205 rs541187205 rs541476497 rs541476497 rs541559503 rs541559503 rs542731477 rs542731477 rs542788685 rs542788685 rs542862721 rs542862721 rs543102655 rs543102655 rs543169976 rs543169976 rs543396484 rs543396484 rs543819656 rs543819656 rs544537552 rs544537552 rs544993450 rs544993450 rs545069251 rs545069251 rs545182672 rs545182672 rs545442721 rs545442721 rs545543006 rs545543006 rs545723608 rs545723608 rs545902396 rs545902396 rs546097516 rs546097516 rs546618890 rs546618890 rs546913189 rs546913189 rs546920053 rs546920053 rs547872584 rs547872584 rs548060607 rs548060607 rs548308309 rs548308309 rs548535835 rs548535835 rs549591442 rs549591442 rs549752201 rs549752201 rs550242478 rs550242478 rs550593229 rs550593229 rs551728328 rs551728328 rs551934875 rs551934875 rs552334736 rs552334736 rs552526626 rs552526626 rs553102142 rs553102142 rs553374974 rs553374974 rs553493893 rs553493893 rs553772531 rs553772531 rs554450717 rs554450717 rs554518000 rs554518000 rs554654291 rs554654291 rs555096765 rs555096765 rs555307838 rs555307838 rs556805545 rs556805545 rs556963987 rs556963987 rs557037291 rs557037291 rs557086655 rs557086655 rs557149875 rs557149875 rs557349894 rs557349894 rs557498893 rs557498893 rs557750734 rs557750734 rs558900028 rs558900028 rs559092673 rs559092673 rs559584043 rs559584043 rs559813325 rs559813325 rs559852985 rs559852985 rs559877284 rs559877284 rs560223954 rs560223954 rs561120786 rs561120786 rs561582810 rs561582810 rs561897029 rs561897029 rs561976823 rs561976823 rs562088484 rs562088484 rs563556167 rs563556167 rs563618893 rs563618893 rs563857373 rs563857373 rs563928337 rs563928337 rs564081279 rs564081279 rs564333282 rs564333282 rs564337125 rs564337125 rs565430784 rs565430784 rs565504637 rs565504637 rs566060460 rs566060460 rs566157889 rs566157889 rs566232377 rs566232377 rs566487845 rs566487845 rs566621790 rs566621790 rs566628840 rs566628840 rs566694789 rs566694789 rs566879681 rs566879681 rs566879924 rs566879924 rs568013286 rs568013286 rs568522445 rs568522445 rs568626087 rs568626087 rs568854812 rs568854812 rs568857471 rs568857471 rs568872885 rs568872885 rs568994782 rs568994782 rs569594762 rs569594762 rs570169363 rs570169363 rs570230461 rs570230461 rs570901474 rs570901474 rs572752322 rs572752322 rs572981151 rs572981151 rs573044028 rs573044028 rs573107270 rs573107270 rs573216318 rs573216318 rs573323324 rs573323324 rs573504444 rs573504444 rs573664009 rs573664009 rs575257981 rs575257981 rs575372731 rs575372731 rs575456948 rs575456948 rs575597962 rs575597962 rs575619743 rs575619743 rs575631177 rs575631177 rs575659268 rs575659268 rs575907816 rs575907816 rs576008849 rs576008849 rs576072441 rs576072441 rs577293593 rs577293593 rs577356377 rs577356377 rs577370922 rs577370922 rs577452799 rs577452799 rs577832450 rs577832450 rs577960405 rs577960405 rs577967528 rs577967528 rs745350127 rs745350127 rs745851721 rs745851721 rs745876302 rs745876302 rs745950679 rs745950679 rs746144907 rs746144907 rs746199962 rs746199962 rs746251270 rs746251270 rs746502080 rs746502080 rs746531663 rs746531663 rs747051281 rs747051281 rs747310269 rs747310269 rs747489118 rs747489118 rs747665404 rs747665404 rs747853042 rs747853042 rs748165463 rs748165463 rs748220414 rs748220414 rs748294572 rs748294572 rs748778794 rs748778794 rs749061564 rs749061564 rs749278971 rs749278971 rs749391977 rs749391977 rs749583763 rs749583763 rs749588608 rs749588608 rs749867848 rs749867848 rs749986577 rs749986577 rs750039547 rs750039547 rs750243947 rs750243947 rs750491987 rs750491987 rs750817171 rs750817171 rs750872367 rs750872367 rs751064879 rs751064879 rs751307015 rs751307015 rs751358067 rs751358067 rs751710883 rs751710883 rs752454699 rs752454699 rs752612390 rs752612390 rs752760255 rs752760255 rs752800376 rs752800376 rs753097110 rs753097110 rs753260093 rs753260093 rs753424422 rs753424422 rs753471486 rs753471486 rs753720726 rs753720726 rs753907002 rs753907002 rs754068227 rs754068227 rs754202853 rs754202853 rs754255966 rs754255966 rs754456696 rs754456696 rs754468619 rs754468619 rs754703640 rs754703640 rs754899778 rs754899778 rs755207994 rs755207994 rs755225578 rs755225578 rs755261007 rs755261007 rs755280733 rs755280733 rs755619531 rs755619531 rs755819599 rs755819599 rs755875279 rs755875279 rs756054897 rs756054897 rs756367929 rs756367929 rs756381851 rs756381851 rs756601565 rs756601565 rs757020824 rs757020824 rs757038801 rs757038801 rs757371304 rs757371304 rs757547530 rs757547530 rs757822552 rs757822552 rs758032535 rs758032535 rs758482314 rs758482314 rs758677702 rs758677702 rs758730747 rs758730747 rs758829036 rs758829036 rs758990229 rs758990229 rs759176909 rs759176909 rs759228752 rs759228752 rs759506778 rs759506778 rs759560294 rs759560294 rs759955297 rs759955297 rs760448307 rs760448307 rs760499522 rs760499522 rs761028235 rs761028235 rs761081354 rs761081354 rs761268746 rs761268746 rs761527666 rs761527666 rs761662800 rs761662800 rs761715933 rs761715933 rs761983322 rs761983322 rs762190753 rs762190753 rs762346692 rs762346692 rs762384477 rs762384477 rs762540142 rs762540142 rs762667527 rs762667527 rs762944768 rs762944768 rs762996252 rs762996252 rs763026937 rs763026937 rs763654177 rs763654177 rs763972456 rs763972456 rs764006608 rs764006608 rs764059619 rs764059619 rs764493524 rs764493524 rs764710522 rs764710522 rs765135517 rs765135517 rs765239689 rs765239689 rs765740115 rs765740115 rs765922043 rs765922043 rs765984180 rs765984180 rs766215617 rs766215617 rs766312558 rs766312558 rs766530068 rs766530068 rs766722506 rs766722506 rs767229492 rs767229492 rs767284389 rs767284389 rs767330275 rs767330275 rs767561501 rs767561501 rs767989615 rs767989615 rs768042502 rs768042502 rs768267394 rs768267394 rs768322975 rs768322975 rs768671059 rs768671059 rs768724373 rs768724373 rs769255069 rs769255069 rs769311874 rs769311874 rs769363207 rs769363207 rs769507232 rs769507232 rs769805645 rs769805645 rs769903398 rs769903398 rs770049086 rs770049086 rs770225013 rs770225013 rs770359619 rs770359619 rs770407653 rs770407653 rs770984609 rs770984609 rs771039898 rs771039898 rs771107572 rs771107572 rs771257778 rs771257778 rs771324959 rs771324959 rs771429111 rs771429111 rs772071686 rs772071686 rs772108659 rs772108659 rs772161967 rs772161967 rs772216071 rs772216071 rs772426973 rs772426973 rs772757316 rs772757316 rs773139859 rs773139859 rs773193166 rs773193166 rs773246401 rs773246401 rs773293778 rs773293778 rs773419597 rs773419597 rs773492585 rs773492585 rs773904241 rs773904241 rs773957525 rs773957525 rs774281696 rs774281696 rs774853347 rs774853347 rs774965040 rs774965040 rs775029790 rs775029790 rs775324994 rs775324994 rs775586134 rs775586134 rs775639261 rs775639261 rs775678644 rs775678644 rs776077848 rs776077848 rs776100553 rs776100553 rs776528959 rs776528959 rs776550112 rs776550112 rs776791472 rs776791472 rs777293488 rs777293488 rs777431755 rs777431755 rs777863940 rs777863940 rs778061443 rs778061443 rs778089050 rs778089050 rs778118626 rs778118626 rs778144230 rs778144230 rs778236694 rs778236694 rs778291811 rs778291811 rs778552642 rs778552642 rs778744418 rs778744418 rs779126214 rs779126214 rs779202734 rs779202734 rs779303849 rs779303849 rs779523888 rs779523888 rs779781730 rs779781730 rs779993208 rs779993208 rs780098955 rs780098955 rs780270249 rs780270249 rs780439844 rs780439844 rs780464719 rs780464719 rs780942003 rs780942003 rs781192454 rs781192454 rs781404551 rs781404551 rs781602858 rs781602858 rs781604476 rs781604476

CFD基因在不同组织中的表达： [UniProt]

正向引物序列

正向引物Tm值

反向引物序列

反向引物Tm值

rank

TTGAGCACCTACTATATGCAG

57

CTCCTGAGATCCAATGATCC

57

CACCCAAGCAACAAAGTCC

60

TAAAGACCAACCAGATGCAG

58

TCACCCAAGCAACAAAGTC

59

AAAGACCAACCAGATGCAG

58

尚未收录相关数据

CFD基因（以及对应的蛋白质）的细胞分布位置：

[UniProt] [GenomeNet]

溶酶体
内涵体
细胞核
细胞质
液泡
细胞膜
细胞外基质
内质网
线粒体
高尔基体
细胞骨架

CFD基因的本体（GO）信息：

GO库代码

对应的蛋白质

来源代码

GO:0004252

K7ERG9(UniProtKB)

IEA

GO:0006508

K7ERG9(UniProtKB)

IEA

GO:0002576

P00746(UniProtKB)

TAS

GO:0004252

P00746(UniProtKB)

TAS

GO:0004252

P00746(UniProtKB)

TAS

GO:0005576

P00746(UniProtKB)

TAS

GO:0005576

P00746(UniProtKB)

TAS

GO:0005576

P00746(UniProtKB)

TAS

GO:0005615

P00746(UniProtKB)

IEA

GO:0006508

P00746(UniProtKB)

IEA

GO:0006956

P00746(UniProtKB)

TAS

GO:0006957

P00746(UniProtKB)

TAS

GO:0008236

P00746(UniProtKB)

TAS

GO:0031093

P00746(UniProtKB)

TAS

GO:0070062

P00746(UniProtKB)

IDA

GO:0070062

P00746(UniProtKB)

IDA

GO:0070062

P00746(UniProtKB)

IDA

序号	作用方式	资源库来源/分值	基因名称	基因名称

可能调控CFD基因的相关microRNA：

hsa-miR-122 hsa-miR-122* hsa-miR-181a hsa-miR-200b hsa-miR-200b* hsa-miR-34a hsa-miR-34a*

通路基因列表

疾病名称

关系值

NofPmids

NofSnps

来源

疾病名称	关系值	NofPmids	NofSnps	来源
Complement Factor D Deficiency	0.240271442	1	0	BeFree_ORPHANET_UNIPROT
Meningococcal Infections	0.120271442	1	0	BeFree_CTD_human
Endometriosis	0.12	1	0	CTD_human
Glomerulonephritis	0.12	1	0	CTD_human
Immunologic Deficiency Syndromes	0.12	2	0	CTD_human
Ovarian Cysts	0.12	1	0	CTD_human
Neisseriaceae Infections	0.12	1	0	CTD_human
Obesity	0.080271442	2	0	BeFree_RGD
Arthus Reaction	0.08	1	0	RGD
Diabetes Mellitus, Experimental	0.08	1	0	RGD
Coronary heart disease	0.002367032	1	0	GAD
Lymphoma, Non-Hodgkin	0.002367032	1	0	GAD
Age related macular degeneration	0.000542884	2	0	BeFree
Geographic Atrophy	0.000271442	1	0	BeFree
Recurrent bacterial infection	0.000271442	1	0	BeFree
Kashin-Beck Disease	0.000271442	1	0	BeFree