CDK9(cyclin-dependent kinase 9) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

9q34.1
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质是细胞周期蛋白依赖性蛋白激酶（CDK）家族的一个成员。 CDK家族成员是高度相似酿酒酵母CDC28的基因产物，和粟酒裂殖酵母CDC2，并称为重要的细胞周期调节。这种激酶被认为是该多蛋白复合物TAK / P-TEFB，它是RNA聚合酶II指导转录和通过磷酸化的RNA聚合酶II的最大亚基的C末端结构域的功能延伸因子的成分。该蛋白质形成复合带，由其调节亚基周期T或细胞周期蛋白K. HIV-1的Tat蛋白调节被发现与该蛋白和细胞周期蛋白T，它建议在艾滋病这种蛋白的一个可能参与相互作用。 [由RefSeq的，2008年7月提供]

OMIM数据库中对CDK9基因的介绍     Wikipedia数据库中对CDK9基因的介绍

基因序列

基因序列

CDK9基因的碱基序列：[NCBI]

基因突变

基因突变

CDK9基因的碱基突变：           显示全部snp
rs8083       rs10460       rs1056472       rs1056473       rs2297214       rs3217730       rs3217731       rs3217732       rs3217733       rs3217734       rs3217735       rs3217736       rs3217737       rs3217738       rs3217739       rs3217740       rs3217741       rs3217742       rs3217743       rs3217744       rs3217745       rs3217746       rs3217747       rs3217748       rs3217749       rs3217750       rs3217751       rs3217752       rs7038902       rs10739697       rs10819306       rs10987727       rs10987728       rs10987729       rs11403971       rs11554104       rs17849564      
rs41316970       rs55640715       rs62587186       rs71380090       rs74376942       rs75386293       rs76742743       rs78317863       rs78405386       rs78857012       rs79648690       rs111297623       rs111384955       rs111479929       rs111834678       rs112272252       rs112278465       rs112443266       rs113604114       rs114028917       rs114465623       rs117478783       rs137949299       rs137963296       rs138685144       rs139206714       rs139278925       rs139560305       rs139856271       rs140058017       rs140078754       rs140701825       rs141070146       rs141577691       rs141597514       rs141709101       rs142044111       rs142085286       rs142566286       rs142704308       rs143544541       rs143718708       rs145338923       rs145381917       rs145740677       rs145899134       rs145977259       rs146248974       rs146297416       rs146765767       rs147073375       rs147693126       rs147936446       rs148032528       rs148244006       rs148342102       rs148443856       rs148919029       rs149456430       rs149950953       rs150060991       rs150246091       rs150564713       rs151087657       rs180685162       rs183267477       rs184296831       rs184616297       rs185111954       rs186886518       rs187547268       rs188112707       rs189441022       rs189495293       rs190633494       rs191368880       rs192286723       rs192958171       rs199764560       rs199872640       rs199885166       rs200127201       rs200268442       rs200376810       rs200589213       rs200868761       rs200917975       rs201025809       rs201136315       rs201184806       rs201259013       rs201475786       rs201862836       rs202049005       rs202170960       rs368336604       rs368523668       rs368750293       rs368784318       rs368789139       rs368797981       rs369043963       rs369561959       rs369777754       rs369965026       rs370044826       rs370526696       rs370750864       rs371317161       rs371684202       rs372067927       rs372079457       rs372145564       rs372276530       rs372545692       rs372696713       rs372825047       rs373394121       rs373459693       rs373517826       rs374405732       rs374516629       rs374585241       rs374586573       rs375012308       rs375388761       rs375458528       rs375548421       rs375572085       rs376244572       rs376698069       rs376812602       rs377000414       rs377085296       rs377243893       rs377539796       rs377758149       rs528334536       rs528403143       rs528738131       rs528961894       rs529276597       rs530304130       rs530352853       rs530690120       rs530938305       rs531064734       rs531127027       rs531341510       rs532334862       rs532603756       rs533121983       rs533145001       rs533180808       rs534193663       rs534407254       rs534510748       rs534880553       rs535039188       rs536203650       rs536460935       rs536792354       rs536856552       rs538521254       rs538585577       rs539167606       rs539189318       rs539422456       rs539486052       rs539785975       rs540712857       rs541022601       rs542079733       rs542466634       rs542635366       rs543799859       rs544755732       rs544759408       rs544840251       rs545030944       rs545129866       rs545390659       rs545485800       rs545948727       rs546438470       rs546674123       rs546689924       rs546924290       rs546949961       rs547262511       rs547771602       rs548015558       rs548636139       rs548699255       rs548924028       rs549094764       rs549917196       rs549980498       rs550315214       rs550376694       rs550439902       rs550641734       rs550716049       rs550907477       rs551042711       rs552379480       rs554378034       rs556088007       rs556489645       rs556627227       rs556710309       rs556880977       rs557627689       rs558093842       rs558381284       rs558508103       rs558654262       rs559881586       rs560331821       rs560433423       rs561652393       rs562230141       rs562230474       rs562298370       rs562638413       rs563333929       rs563946978       rs564175592       rs564361553       rs564493865       rs564572361       rs564712203       rs565594788       rs566601726       rs567188145       rs567498379       rs567829669       rs567892441       rs567953778       rs568443841       rs568509308       rs568912005       rs569838695       rs569874524       rs570125365       rs570477616       rs570610324       rs570906261       rs571805959       rs572065012       rs572591176       rs572778243       rs573466515       rs573473931       rs573934552       rs574082027       rs575961189       rs576021592       rs576089830       rs576121481       rs576155177       rs577501513       rs745340199       rs745632670       rs745709237       rs745870791       rs745944666       rs745986749       rs746145143       rs746216061       rs746257072       rs746324387       rs746598695       rs746864836       rs747091098       rs747148423       rs747301138       rs747387277       rs747453571       rs747730447       rs747946620       rs747970657       rs747985794       rs748038622       rs748237241       rs748288731       rs748495865       rs748529804       rs748596903       rs749147935       rs749397034       rs749487652       rs749596460       rs749639384       rs749683780       rs749896017       rs749940295       rs749950582       rs749983819       rs749997551       rs750486411       rs750537619       rs750748568       rs750834413       rs751056570       rs751365977       rs751626173       rs751860076       rs751991570       rs752013238       rs752243000       rs752475388       rs752524938       rs752582972       rs752720167       rs752742844       rs752910860       rs752912301       rs753143249       rs753255887       rs753378672       rs753417800       rs753542894       rs753758776       rs753912033       rs753944760       rs754288051       rs754446615       rs754778321       rs754831384       rs754937212       rs755014396       rs755047732       rs755547628       rs755748657       rs755776114       rs755852257       rs755920229       rs755939591       rs756145683       rs756164503       rs756177544       rs756194891       rs756684461       rs756774882       rs756913144       rs756987735       rs757201394       rs757281821       rs757364410       rs757653989       rs757703558       rs757705410       rs757828715       rs757889331       rs758087169       rs758230646       rs758268441       rs758316825       rs758446860       rs758843054       rs759014029       rs759089495       rs759142793       rs759417363       rs759496397       rs759675808       rs759866908       rs759915993       rs760023385       rs760231401       rs760251322       rs760282666       rs760668207       rs760683797       rs760988808       rs761228208       rs761350967       rs761402308       rs761535526       rs761561096       rs761765306       rs761776626       rs761794166       rs762026448       rs762157126       rs762456826       rs762673744       rs762773250       rs763097185       rs763144479       rs763279861       rs763329642       rs763433765       rs763517666       rs763581624       rs763730809       rs763822642       rs763885651       rs764472088       rs764624212       rs764921447       rs764963508       rs765016720       rs765076795       rs765192342       rs765527912       rs765530478       rs765581062       rs765744959       rs765767956       rs765921647       rs766106317       rs766161082       rs766316927       rs766337146       rs766340319       rs766414012       rs766848600       rs766939296       rs767163242       rs767223715       rs767241242       rs767296801       rs767418586       rs767620581       rs767851738       rs768088819       rs768162338       rs768177225       rs768527415       rs768794966       rs768849649       rs768949456       rs769050794       rs769065822       rs769082728       rs769188538       rs769375453       rs769429948       rs769930999       rs770049111       rs770058883       rs770089754       rs770113642       rs770239486       rs770506343       rs770616688       rs770752687       rs770932885       rs771132092       rs771187222       rs771220295       rs771229305       rs771561004       rs771708473       rs771759708       rs771995185       rs772280389       rs772377103       rs772437157       rs772498938       rs772642497       rs772694126       rs773045544       rs773135587       rs773263896       rs773403021       rs773489224       rs773619937       rs773778565       rs773818931       rs774013467       rs774177908       rs774385639       rs774630568       rs774633888       rs774680949       rs774716173       rs774801281       rs774881075       rs774932151       rs775012342       rs775163113       rs775287060       rs775530641       rs775691097       rs775692100       rs775710179       rs775765477       rs775815842       rs775888687       rs776011945       rs776066835       rs776278851       rs776332336       rs776385767       rs776586015       rs776797894       rs776813335       rs776932315       rs776976149       rs776977894       rs777029408       rs777066206       rs777252301       rs777544420       rs777679934       rs777704617       rs777735060       rs777773341       rs777792275       rs777924310       rs777977604       rs778384628       rs778441641       rs778441690       rs778462348       rs778878328       rs778916606       rs778962712       rs779013986       rs779029217       rs779167622       rs779209522       rs779299478       rs779479066       rs779551319       rs779676185       rs780038803       rs780095447       rs780150458       rs780150586       rs780276638       rs780402171       rs780602892       rs780615861       rs781103819       rs781196606       rs781197980       rs781314206       rs781408491       rs781515520       rs781568641       rs781588545       rs781754223      

基因表达

基因表达

CDK9基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTGAAGAAGGTGCTGATGG
58
ATCTTGATCTCCCGCAAGG
59
TGAAGAAGGTGCTGATGGA
58
ATCTTGATCTCCCGCAAGG
59
CAGAAACAAGATCCTGCATAGG
59
CAAAGTCTGCCAGCTTCAG
59
CCCTCATCAGTCAGCTCTG
59
ATAGTTGTCCACGTTTGGC
58
CCCTCATCAGTCAGCTCTG
59
CATAGTTGTCCACGTTTGGC
59
ACGCTGTCTGAGATCAAGAG
59
CCTATGCAGGATCTTGTTTCTG
59
CTGAAGAAGGTGCTGATGGA
59
ATCTTGATCTCCCGCAAGG
59
GAAACAAGATCCTGCATAGGG
58
CAAAGTCTGCCAGCTTCAG
59
CCCTCATCAGTCAGCTCTG
59
TCATAGTTGTCCACGTTTGG
58

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CDK9基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CDK9基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000979
P50750(UniProtKB)
IEA
GO:0001223
P50750(UniProtKB)
IPI
GO:0003677
P50750(UniProtKB)
IDA
GO:0003682
P50750(UniProtKB)
ISS
GO:0004672
P50750(UniProtKB)
TAS
GO:0004674
P50750(UniProtKB)
TAS
GO:0004693
P50750(UniProtKB)
IDA
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005515
P50750(UniProtKB)
IPI
GO:0005524
P50750(UniProtKB)
IEA
GO:0005654
P50750(UniProtKB)
IDA
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005654
P50750(UniProtKB)
TAS
GO:0005737
P50750(UniProtKB)
IEA
GO:0006281
P50750(UniProtKB)
IEA
GO:0006282
P50750(UniProtKB)
IDA
GO:0006366
P50750(UniProtKB)
TAS
GO:0006367
P50750(UniProtKB)
TAS
GO:0006368
P50750(UniProtKB)
TAS
GO:0006368
P50750(UniProtKB)
TAS
GO:0006468
P50750(UniProtKB)
IDA
GO:0008023
P50750(UniProtKB)
IDA
GO:0008024
P50750(UniProtKB)
IDA
GO:0008024
P50750(UniProtKB)
IDA
GO:0008283
P50750(UniProtKB)
TAS
GO:0008353
P50750(UniProtKB)
IDA
GO:0010613
P50750(UniProtKB)
IEA
GO:0016020
P50750(UniProtKB)
IDA
GO:0016301
P50750(UniProtKB)
TAS
GO:0016605
P50750(UniProtKB)
IDA
GO:0031056
P50750(UniProtKB)
IDA
GO:0031297
P50750(UniProtKB)
IDA
GO:0033129
P50750(UniProtKB)
IMP
GO:0042493
P50750(UniProtKB)
IEA
GO:0042795
P50750(UniProtKB)
TAS
GO:0043231
P50750(UniProtKB)
IDA
GO:0045944
P50750(UniProtKB)
IMP
GO:0045944
P50750(UniProtKB)
TAS
GO:0050434
P50750(UniProtKB)
TAS
GO:0051147
P50750(UniProtKB)
IMP
GO:0071157
P50750(UniProtKB)
IDA
GO:0071345
P50750(UniProtKB)
IDA
GO:0097322
P50750(UniProtKB)
IDA
GO:1900364
P50750(UniProtKB)
IMP
GO:1903839
P50750(UniProtKB)
IDA
GO:2001168
P50750(UniProtKB)
IMP
GO:0007346
P50750(UniProtKB)
IMP
GO:0004672
X6RE90(UniProtKB)
IEA
GO:0005524
X6RE90(UniProtKB)
IEA
GO:0006468
X6RE90(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CDK9基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Diabetes Mellitus, Experimental 0.08 1 0 RGD
HIV Infections 0.00434307 16 0 BeFree
Neuroblastoma 0.002995792 1 0 BeFree_LHGDN
Mammary Neoplasms 0.00272435 1 0 LHGDN
Malignant neoplasm of breast 0.000814326 3 0 BeFree
leukemia 0.000814326 3 0 BeFree
Liver carcinoma 0.000814326 3 0 BeFree
Cytomegalovirus Infections 0.000542884 2 0 BeFree
Heart failure 0.000542884 2 0 BeFree
Congestive heart failure 0.000542884 2 0 BeFree
Virus Diseases 0.000542884 2 0 BeFree
Solid tumour 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Glioblastoma 0.000271442 1 0 BeFree
Influenza 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Lung diseases 0.000271442 1 0 BeFree
Lymphoma 0.000271442 1 0 BeFree
Lymphoma, Follicular 0.000271442 1 0 BeFree
Multiple Myeloma 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Pancreatic Neoplasm 0.000271442 1 0 BeFree
Respiratory Syncytial Virus Infections 0.000271442 1 0 BeFree
Septicemia 0.000271442 1 0 BeFree
Adenocarcinoma of lung (disorder) 0.000271442 1 0 BeFree
Ki-1+ Anaplastic Large Cell Lymphoma 0.000271442 1 0 BeFree
Neuroectodermal Tumor, Primitive 0.000271442 1 0 BeFree
Sepsis 0.000271442 1 0 BeFree
Metastatic melanoma 0.000271442 1 1 BeFree
Extraosseous Ewings sarcoma-primitive neuroepithelial tumor 0.000271442 1 0 BeFree
Respiratory syncytial virus (RSV) infection in conditions classified elsewhere and of unspecified site 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Hematologic Neoplasms 0.000271442 1 0 BeFree
Carcinogenesis 0.000271442 1 0 BeFree
Leukemogenesis 0.000271442 1 0 BeFree
Prostate carcinoma 0.000271442 1 0 BeFree
Ewings sarcoma-primitive neuroectodermal tumor (PNET) 0.000271442 1 0 BeFree
Central neuroblastoma 0.000271442 1 0 BeFree
Cardiomyopathies 0.000271442 1 0 BeFree
Inflammatory disorder 0.000271442 1 0 BeFree
NUT Midline Carcinoma 0.000271442 1 0 BeFree
Transient Myeloproliferative Disorder of Down Syndrome 0.000271442 1 0 BeFree

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