更多...
收起
The protein encoded by this gene is a membrane receptor that is activated by the binding of CD28 or CTLA-4. The activated protein induces T-cell proliferation and cytokine production. This protein can act as a receptor for adenovirus subgroup B and may play a role in lupus neuropathy. [provided by RefSeq, Aug 2011]
[中文简述(自动翻译):]  由该基因编码的蛋白质是由结合CD28或CTLA-4的活化的膜受体。活化的蛋白诱导T细胞增殖和细胞因子产生。这种蛋白质可以充当腺病毒亚组B中的受体和可能在狼疮神经病的作用。 [由RefSeq的,2011年8月提供]
CD80基因(以及对应的蛋白质)的细胞分布位置:
CD80基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Celiac Disease | 0.125005506 | 3 | 2 | BeFree_CTD_human_GAD |
Lupus Erythematosus, Systemic | 0.123995683 | 7 | 1 | BeFree_GAD_GWASCAT |
IGA Glomerulonephritis | 0.122995792 | 2 | 0 | BeFree_CTD_human_LHGDN |
Biliary cirrhosis | 0.12 | 1 | 0 | CTD_human |
Vitiligo | 0.12 | 1 | 0 | CTD_human |
Glioma | 0.080814326 | 4 | 0 | BeFree_RGD |
Experimental Autoimmune Encephalomyelitis | 0.080271442 | 2 | 0 | BeFree_RGD |
Periodontal Diseases | 0.080271442 | 2 | 0 | BeFree_RGD |
Adult T-Cell Lymphoma/Leukemia | 0.08 | 1 | 0 | RGD |
Anti-Glomerular Basement Membrane Disease | 0.08 | 1 | 0 | RGD |
Renal Insufficiency | 0.08 | 0 | 0 | RGD |
Liver carcinoma | 0.008630058 | 6 | 0 | BeFree_GAD_LHGDN |
melanoma | 0.006524536 | 15 | 0 | BeFree_LHGDN |
Neoplasm Metastasis | 0.005991584 | 3 | 0 | BeFree_LHGDN |
Rheumatoid Arthritis | 0.005905708 | 4 | 0 | BeFree_GAD_LHGDN |
Infection | 0.0054487 | 2 | 0 | LHGDN |
Hepatitis C | 0.004734064 | 2 | 0 | GAD |
HIV Infections | 0.004624443 | 8 | 0 | BeFree_LHGDN |
Leukemia, Myelocytic, Acute | 0.004071628 | 15 | 0 | BeFree |
Ulcerative Colitis | 0.003538676 | 4 | 0 | BeFree_LHGDN |
Multiple Sclerosis | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Malignant neoplasm of lung | 0.002909916 | 3 | 0 | BeFree_GAD |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.002909916 | 3 | 0 | BeFree_GAD |
Squamous cell carcinoma | 0.00272435 | 1 | 0 | LHGDN |
Herpes Simplex Infections | 0.00272435 | 1 | 0 | LHGDN |
Stomach Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Thyroiditis | 0.00272435 | 1 | 0 | LHGDN |
Tuberculosis | 0.00272435 | 1 | 0 | LHGDN |
B-Cell Lymphomas | 0.00272435 | 1 | 0 | LHGDN |
Coronary Artery Disease | 0.00272435 | 1 | 0 | LHGDN |
Asthma | 0.002638474 | 2 | 0 | BeFree_GAD |
Malignant neoplasm of urinary bladder | 0.002638474 | 2 | 0 | BeFree_GAD |
Chronic Obstructive Airway Disease | 0.002638474 | 2 | 0 | BeFree_GAD |
Respiratory Syncytial Virus Infections | 0.002638474 | 2 | 0 | BeFree_GAD |
Sarcoidosis | 0.002638474 | 1 | 0 | BeFree_GAD |
Bronchiolitis, Viral | 0.002367032 | 1 | 0 | GAD |
Subacute Sclerosing Panencephalitis | 0.002367032 | 1 | 0 | GAD |
Chronic Lymphocytic Leukemia | 0.001900093 | 7 | 0 | BeFree |
Multiple Myeloma | 0.001900093 | 7 | 0 | BeFree |
Breast Carcinoma | 0.001900093 | 7 | 0 | BeFree |
Malignant neoplasm of breast | 0.001628651 | 6 | 0 | BeFree |
leukemia | 0.001628651 | 6 | 0 | BeFree |
Renal Cell Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of stomach | 0.001357209 | 5 | 0 | BeFree |
Stomach Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Ovarian Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Epithelial ovarian cancer | 0.001085767 | 4 | 0 | BeFree |
Diabetes Mellitus, Insulin-Dependent | 0.000814326 | 3 | 0 | BeFree |
Influenza | 0.000814326 | 3 | 0 | BeFree |
Lymphoma | 0.000814326 | 3 | 0 | BeFree |
Lipoid nephrosis | 0.000814326 | 3 | 0 | BeFree |
Neuroblastoma | 0.000814326 | 3 | 0 | BeFree |
Cervix carcinoma | 0.000814326 | 3 | 0 | BeFree |
Secondary malignant neoplasm of lymph node | 0.000814326 | 3 | 1 | BeFree |
Central neuroblastoma | 0.000814326 | 3 | 0 | BeFree |
Glomerulonephritis, Minimal Change | 0.000814326 | 3 | 0 | BeFree |
Autoimmune Diseases | 0.000542884 | 2 | 0 | BeFree |
Non-Small Cell Lung Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Malignant tumor of cervix | 0.000542884 | 2 | 0 | BeFree |
Primary biliary cirrhosis | 0.000542884 | 2 | 0 | BeFree |
Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Diabetes | 0.000542884 | 2 | 0 | BeFree |
Diabetes Mellitus | 0.000542884 | 2 | 0 | BeFree |
Eczema | 0.000542884 | 2 | 0 | BeFree |
Acute lymphocytic leukemia | 0.000542884 | 2 | 0 | BeFree |
Myeloid Leukemia, Chronic | 0.000542884 | 2 | 0 | BeFree |
Nephrotic Syndrome | 0.000542884 | 2 | 0 | BeFree |
Carcinoma breast stage IV | 0.000542884 | 2 | 0 | BeFree |
Malonic aciduria | 0.000542884 | 2 | 0 | BeFree |
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | 0.000542884 | 2 | 0 | BeFree |
Malignant melanoma of eye | 0.000542884 | 2 | 0 | BeFree |
Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
Carcinoma of lung | 0.000542884 | 2 | 0 | BeFree |
Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Macular dystrophy, corneal type 1 | 0.000542884 | 2 | 0 | BeFree |
IMMUNE SUPPRESSION | 0.000542884 | 2 | 0 | BeFree |
Nasopharyngeal carcinoma | 0.000542884 | 2 | 0 | BeFree |
Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Adenovirus Infections | 0.000271442 | 1 | 0 | BeFree |
Arthritis, Psoriatic | 0.000271442 | 1 | 0 | BeFree |
Brain Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Transitional Cell | 0.000271442 | 1 | 0 | BeFree |
Uterine Cervical Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Eosinophilia | 0.000271442 | 1 | 0 | BeFree |
Esophageal Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Gingival Diseases | 0.000271442 | 1 | 0 | BeFree |
Hepatitis B | 0.000271442 | 1 | 0 | BeFree |
Hodgkin Disease | 0.000271442 | 1 | 0 | BeFree |
Leprosy, Lepromatous | 0.000271442 | 1 | 0 | BeFree |
Lupus Vulgaris | 0.000271442 | 1 | 0 | BeFree |
Lupus Erythematosus, Discoid | 0.000271442 | 1 | 0 | BeFree |
nervous system disorder | 0.000271442 | 1 | 0 | BeFree |
Septicemia | 0.000271442 | 1 | 0 | BeFree |
Dermatologic disorders | 0.000271442 | 1 | 0 | BeFree |
Virus Diseases | 0.000271442 | 1 | 0 | BeFree |
Lymphoma, T-Cell, Cutaneous | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
Esophageal carcinoma | 0.000271442 | 1 | 0 | BeFree |
Dermatitis, Irritant | 0.000271442 | 1 | 0 | BeFree |
Cervical Intraepithelial Neoplasia | 0.000271442 | 1 | 0 | BeFree |
Uveal melanoma | 0.000271442 | 1 | 0 | BeFree |
Malignant ascites | 0.000271442 | 1 | 0 | BeFree |
Functional proteinuria | 0.000271442 | 1 | 0 | BeFree |
Sepsis | 0.000271442 | 1 | 0 | BeFree |
Chronic arthritis | 0.000271442 | 1 | 0 | BeFree |
Axonal neuropathy | 0.000271442 | 1 | 0 | BeFree |
Solid tumour | 0.000271442 | 1 | 0 | BeFree |
Thyroid associated opthalmopathies | 0.000271442 | 1 | 0 | BeFree |
Stable angina | 0.000271442 | 1 | 0 | BeFree |
Lupus Erythematosus | 0.000271442 | 1 | 0 | BeFree |
Neuropathy | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of esophagus | 0.000271442 | 1 | 0 | BeFree |
Primary sclerosing cholangitis | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of bladder | 0.000271442 | 1 | 0 | BeFree |
Varicella zoster | 0.000271442 | 1 | 0 | BeFree |
early pregnancy | 0.000271442 | 1 | 0 | BeFree |
Acute Coronary Syndrome | 0.000271442 | 1 | 0 | BeFree |
Neuroborreliosis | 0.000271442 | 1 | 0 | BeFree |
Sarcoma | 0.000271442 | 1 | 0 | BeFree |
Eosinophilic disorder | 0.000271442 | 1 | 0 | BeFree |
Non-Malignant Ascites Adverse Event | 0.000271442 | 1 | 0 | BeFree |
Disorder characterized by eosinophilia | 0.000271442 | 1 | 0 | BeFree |
Nephrotic syndrome in children | 0.000271442 | 1 | 0 | BeFree |
忘记密码? 点击找回密码.
扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。