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CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010]
[中文简述(自动翻译):]  CD2]是在所有外周血T细胞上表达的人T淋巴细胞系(由休厄尔等,1986 [搜索PubMed 3490670]总结。)的表面抗原。它是最早的T细胞标志物之一,是存在于胸腺细胞的95%以上;它也对某些天然杀伤细胞,但不是在B淋巴细胞中找到。针对CD2单克隆抗体抑制与绵羊红细胞玫瑰花结的形成,这表明CD2是红细胞受体或与它密切相关的。[通过OMIM,2010年7月供给]
CD2基因(以及对应的蛋白质)的细胞分布位置:
CD2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Rheumatoid Arthritis | 0.122367032 | 2 | 0 | CTD_human_GAD |
| Nephrotic Syndrome | 0.12 | 1 | 0 | CTD_human |
| Thrombosis | 0.12 | 1 | 0 | CTD_human |
| Chronic Lymphocytic Leukemia | 0.002995792 | 2 | 0 | BeFree_LHGDN |
| Infection | 0.00272435 | 1 | 0 | LHGDN |
| Leukemia, Myelocytic, Acute | 0.000542884 | 2 | 0 | BeFree |
| Autoimmune Diseases | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Experimental Autoimmune Encephalomyelitis | 0.000271442 | 1 | 0 | BeFree |
| Eosinophilia | 0.000271442 | 1 | 0 | BeFree |
| Influenza | 0.000271442 | 1 | 0 | BeFree |
| leukemia | 0.000271442 | 1 | 0 | BeFree |
| Acute lymphocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
| Acute Promyelocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
| Lupus Vulgaris | 0.000271442 | 1 | 0 | BeFree |
| Lupus Erythematosus, Discoid | 0.000271442 | 1 | 0 | BeFree |
| Lupus Erythematosus, Systemic | 0.000271442 | 1 | 0 | BeFree |
| Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
| Brazilian purpuric fever | 0.000271442 | 1 | 0 | BeFree |
| Lupus Erythematosus | 0.000271442 | 1 | 0 | BeFree |
| X-Linked Lymphoproliferative Disorder | 0.000271442 | 1 | 0 | BeFree |
| Eosinophilic disorder | 0.000271442 | 1 | 0 | BeFree |
| Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
| Disorder characterized by eosinophilia | 0.000271442 | 1 | 0 | BeFree |
| Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.000271442 | 1 | 0 | BeFree |
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