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The eukaryotic cell cycle is governed by cyclin-dependent protein kinases (CDKs) whose activities are regulated by cyclins and CDK inhibitors. The 8 species of cyclins reported in mammals, cyclins A through H, share a conserved amino acid sequence of about 90 residues called the cyclin box. The amino acid sequence of cyclin G is well conserved among mammals. The nucleotide sequence of cyclin G1 and cyclin G2 are 53% identical. Unlike cyclin G1, cyclin G2 contains a C-terminal PEST protein destabilization motif, suggesting that cyclin G2 expression is tightly regulated through the cell cycle. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  真核细胞周期是由细胞周期依赖性蛋白激酶(CDK的),其活动受细胞周期蛋白和CDK抑制剂调节控制。在哺乳动物中报道了8种细胞周期蛋白的,细胞周期蛋白A至H,共享约90残基被称为细胞周期蛋白盒的保守氨基酸序列。细胞周期蛋白G的氨基酸序列是公哺乳动物中是保守的。细胞周期蛋白G1和细胞周期蛋白G2的核苷酸序列53%相同。不像蛋白G1,细胞周期蛋白G2包含一个C-末端PEST蛋白质不稳定基序,这表明细胞周期蛋白G2表达通过细胞周期紧密调节。 [由RefSeq的,2008年7月提供]
CCNG2基因(以及对应的蛋白质)的细胞分布位置:
CCNG2基因的本体(GO)信息:
| 疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
| Malignant neoplasm of ovary | 0.002909916 | 3 | 0 | BeFree_GAD |
| ovarian neoplasm | 0.00272435 | 1 | 0 | LHGDN |
| Rheumatoid Arthritis | 0.002367032 | 1 | 1 | GAD |
| Narcolepsy | 0.002367032 | 1 | 0 | GAD |
| Secondary malignant neoplasm of lymph node | 0.000814326 | 3 | 0 | BeFree |
| Ovarian Carcinoma | 0.000542884 | 2 | 0 | BeFree |
| Malignant neoplasm of breast | 0.000271442 | 1 | 0 | BeFree |
| Renal Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Esophageal Neoplasms | 0.000271442 | 1 | 0 | BeFree |
| Glioblastoma | 0.000271442 | 1 | 0 | BeFree |
| Glioma | 0.000271442 | 1 | 0 | BeFree |
| Myeloid Leukemia, Chronic | 0.000271442 | 1 | 0 | BeFree |
| Multiple Myeloma | 0.000271442 | 1 | 0 | BeFree |
| Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Obesity | 0.000271442 | 1 | 0 | BeFree |
| Gestational Diabetes | 0.000271442 | 1 | 0 | BeFree |
| Esophageal carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of mouth | 0.000271442 | 1 | 0 | BeFree |
| Lip and Oral Cavity Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Laryngeal Squamous Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of esophagus | 0.000271442 | 1 | 0 | BeFree |
| Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
| Epithelial ovarian cancer | 0.000271442 | 1 | 0 | BeFree |
| Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Central neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
| Malignant neoplasm of kidney | 0.000271442 | 1 | 0 | BeFree |
| Renal carcinoma | 0.000271442 | 1 | 0 | BeFree |
| Triple Negative Breast Neoplasms | 0.000271442 | 1 | 0 | BeFree |
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