CCNA2(cyclin A2) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

4q27
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. In contrast to cyclin A1, which is present only in germ cells, this cyclin is expressed in all tissues tested. This cyclin binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于高度保守的细胞周期蛋白家族，其成员通过细胞周期的特征是急剧周期性的蛋白质丰度。细胞周期蛋白作为CDK激酶的监管。不同细胞周期蛋白表现出不同的表达和降解模式这有助于每个有丝分裂事件的时间协调。在对比细胞周期蛋白A1，这是目前仅在生殖细胞，这种细胞周期蛋白在所有测试的组织中表达。这个周期蛋白结合并激活CDC2或CDK2激酶，从而促进两种细胞周期G1 / S期和G2 / M过渡。 [由RefSeq的，2008年7月提供]

OMIM数据库中对CCNA2基因的介绍     Wikipedia数据库中对CCNA2基因的介绍

基因序列

基因序列

CCNA2基因的碱基序列：[NCBI]

基因突变

基因突变

CCNA2基因的碱基突变：           显示全部snp
rs769235       rs769236       rs1055823       rs1507996       rs3217753       rs3217754       rs3217755       rs3217756       rs3217757       rs3762840       rs80171619       rs112462816       rs112640902       rs116436977       rs117717953       rs138489532       rs140252747       rs181687808       rs185368516       rs186181139       rs186572976       rs190252263       rs190453459       rs199782217       rs200470633       rs371449601       rs375825705       rs397995200       rs527647078       rs527811154       rs529999534       rs532679737       rs534445093       rs536562113       rs537342982       rs538797584       rs540593732      
rs542972752       rs543380286       rs544492413       rs550245263       rs554157578       rs556935490       rs559606088       rs565401520       rs567922354       rs570185494       rs570335275       rs570995801       rs571659772       rs572558423       rs574396532       rs577071672       rs746139675       rs749023800       rs752107050       rs755954478       rs757805445       rs759152556       rs760833157       rs762111748       rs765649058       rs767033569       rs770862166       rs775478831       rs777882672       rs779259401       rs769237       rs769238       rs769239       rs769240       rs769241       rs769242       rs769243       rs769244       rs769245       rs769246       rs769248       rs769249       rs769250       rs769251       rs769252       rs769253       rs769254       rs769255       rs1051881       rs1396080       rs1507987       rs1507988       rs2071486       rs3217758       rs3217759       rs3217760       rs3217761       rs3217762       rs3217763       rs3217764       rs3217765       rs3217766       rs3217767       rs3217768       rs3217769       rs3217770       rs3217771       rs3217772       rs3217773       rs3217774       rs3217775       rs3217776       rs3217777       rs3217778       rs3217779       rs3217780       rs3217781       rs3217782       rs5031014       rs7436040       rs12650127       rs13117978       rs13117986       rs34655655       rs34932724       rs35942869       rs57392792       rs62322622       rs62322623       rs62322624       rs72915963       rs76388456       rs76471490       rs79254801       rs79446862       rs80337507       rs111240582       rs111281266       rs111499975       rs112004858       rs112011422       rs112405446       rs112552992       rs113106031       rs113190999       rs113448823       rs113924029       rs114899657       rs114973771       rs115356360       rs116139349       rs116782449       rs138990136       rs139676936       rs140275604       rs140420596       rs140695662       rs141312936       rs141379119       rs142242489       rs142252401       rs142481279       rs143489679       rs144930379       rs145812656       rs145910336       rs147182750       rs147433128       rs147823966       rs147878070       rs148015288       rs149059650       rs149621340       rs149686084       rs149937033       rs150092301       rs180785364       rs181032306       rs181520027       rs182402802       rs182550014       rs183616634       rs184536514       rs185066716       rs187160387       rs188327001       rs188678368       rs188724135       rs189692113       rs190271331       rs191647601       rs192441657       rs199524406       rs199765041       rs199811392       rs199853275       rs200022667       rs200078687       rs200175803       rs200206351       rs200394944       rs200400486       rs200516052       rs200618568       rs200756267       rs201101230       rs201224124       rs201310057       rs201466775       rs201638431       rs201943832       rs202018156       rs202158297       rs367814159       rs368266173       rs368392641       rs368399089       rs368548554       rs368906532       rs369373809       rs369403322       rs369469569       rs370029186       rs370178349       rs370571856       rs370704722       rs372013591       rs372379287       rs373413178       rs373415242       rs373850462       rs374918067       rs375866565       rs376051959       rs376488849       rs376843753       rs377438764       rs377475341       rs377511727       rs377691288       rs527440736       rs528746053       rs529964740       rs531378613       rs531485009       rs531726293       rs531809506       rs532310474       rs533166200       rs533701450       rs534409022       rs534530611       rs535743148       rs535781764       rs536327566       rs536808129       rs537870734       rs538192147       rs538794460       rs539024839       rs539720464       rs540055881       rs540218592       rs540632706       rs540758624       rs540800077       rs541777543       rs542110510       rs542735986       rs542968589       rs543567732       rs543578205       rs545851481       rs546148344       rs546601223       rs547194202       rs547941906       rs548341818       rs548666437       rs549001068       rs549377974       rs549495039       rs549907729       rs549995122       rs550113320       rs550453069       rs551100409       rs551113401       rs551167564       rs551783769       rs553346887       rs554122581       rs554284100       rs554546961       rs555738599       rs555757234       rs556706240       rs556901561       rs556920628       rs556945082       rs557653500       rs559089990       rs559300681       rs559337897       rs559479723       rs560736729       rs560800583       rs563590428       rs563697679       rs564519657       rs564734459       rs564792475       rs566500206       rs567149295       rs567664051       rs567971221       rs568350890       rs568444209       rs568877013       rs569028278       rs570909867       rs571669071       rs571696362       rs571745836       rs572070376       rs572911780       rs572949131       rs573763214       rs574202999       rs574967604       rs575393227       rs575830447       rs576055979       rs576061494       rs577033058       rs577233575       rs578241292       rs578250642       rs745307268       rs745574961       rs745615345       rs746063225       rs746256012       rs746359059       rs746448743       rs746475533       rs746570518       rs746754770       rs746929651       rs747013132       rs747226357       rs747255270       rs747298248       rs747339409       rs747533838       rs747646576       rs748007213       rs748370398       rs748868039       rs748917790       rs749044752       rs749115043       rs749239926       rs749324326       rs749522181       rs749822977       rs749857004       rs750005162       rs750044692       rs750203991       rs750247192       rs750385370       rs750470499       rs750598338       rs750664389       rs750837485       rs750866939       rs751032291       rs751226309       rs751255089       rs751264133       rs751458182       rs751521188       rs751739171       rs752110564       rs752305454       rs752387878       rs752439359       rs752651357       rs752777555       rs752882999       rs753064389       rs753267757       rs753347036       rs753609531       rs753686186       rs753775857       rs753999037       rs754155366       rs754178369       rs754454820       rs754474201       rs754499029       rs754673374       rs754835875       rs754938060       rs755382269       rs755582640       rs755590052       rs755636747       rs755932933       rs756376701       rs756418898       rs756439384       rs756484028       rs756682560       rs756855281       rs757068837       rs757266991       rs757306594       rs757312369       rs757358346       rs757585851       rs757896752       rs758098987       rs758147266       rs758257071       rs758310981       rs758353782       rs758540488       rs758583433       rs759463605       rs759629987       rs759791470       rs759875417       rs759963439       rs760015473       rs760400347       rs760490256       rs760579961       rs760668162       rs760690278       rs761122967       rs761352345       rs761443767       rs761508544       rs761532498       rs761539659       rs761622428       rs761627971       rs761670960       rs761730636       rs761870224       rs762137651       rs762146835       rs762199564       rs762287419       rs762304434       rs762488495       rs762548324       rs763064965       rs763244939       rs763304102       rs763330345       rs763335932       rs763427765       rs763457015       rs763610093       rs764163813       rs764229367       rs764339086       rs764417302       rs764430823       rs764626513       rs764812450       rs764900320       rs765097633       rs765156734       rs765213780       rs765340466       rs765557163       rs765651222       rs765954111       rs766002721       rs766013419       rs766175146       rs766337790       rs766543347       rs766583616       rs766625234       rs766711975       rs767052237       rs767064378       rs767158418       rs767316185       rs767321696       rs767365609       rs767670935       rs767762684       rs767930012       rs768000961       rs768161510       rs768307852       rs768348252       rs768369229       rs768409361       rs768593531       rs768779689       rs768810687       rs769130304       rs769148655       rs769473260       rs769491313       rs769522699       rs769627949       rs769819111       rs769958780       rs770197303       rs770483789       rs770489544       rs770657777       rs770863746       rs771001230       rs771290221       rs771377470       rs771476010       rs771579900       rs771622457       rs771803520       rs772000562       rs772097508       rs772368171       rs772496110       rs772507554       rs772900561       rs772943583       rs773046506       rs773319898       rs773694004       rs773740799       rs773876155       rs774150508       rs774324136       rs774377841       rs774522287       rs774718459       rs774718623       rs774772784       rs774778412       rs774868110       rs774950274       rs775017474       rs775274179       rs775390118       rs775406517       rs775599255       rs775603318       rs775684601       rs775761154       rs776408693       rs776412937       rs776472243       rs776494631       rs776541235       rs776616171       rs777203965       rs777213656       rs777235937       rs777725892       rs777753608       rs777870825       rs777991915       rs777992077       rs778353739       rs778370868       rs778460904       rs778497334       rs778565779       rs779011879       rs779119584       rs779576613       rs779606000       rs779616663       rs779707812       rs780269767       rs780635306       rs780748760       rs781326696       rs781410030       rs781649136      

基因表达

基因表达

CCNA2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GTTCCTGTCTTCCATGTCAG
58
TCAAACTTTGAGGCTAACAGC
59
TGCCATCAGTTATTGCTGG
58
GTATTAATGATTCAGGCCAGCT
59
GTTCCTGTCTTCCATGTCAG
58
TCAAACTTTGAGGCTAACAGC
59
GCCATCAGTTATTGCTGGA
58
CGTATTAATGATTCAGGCCAG
57
GCCATCAGTTATTGCTGGA
58
CGTATTAATGATTCAGGCCAG
57
TGCCATCAGTTATTGCTGG
58
GTATTAATGATTCAGGCCAGCT
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CCNA2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CCNA2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000079
P20248(UniProtKB)
IEA
GO:0001939
P20248(UniProtKB)
IEA
GO:0001940
P20248(UniProtKB)
IEA
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005515
P20248(UniProtKB)
IPI
GO:0005634
P20248(UniProtKB)
IDA
GO:0005654
P20248(UniProtKB)
IDA
GO:0005654
P20248(UniProtKB)
TAS
GO:0005737
P20248(UniProtKB)
IDA
GO:0005794
P20248(UniProtKB)
IDA
GO:0007067
P20248(UniProtKB)
IEA
GO:0007095
P20248(UniProtKB)
TAS
GO:0007265
P20248(UniProtKB)
IEP
GO:0016032
P20248(UniProtKB)
IEA
GO:0019901
P20248(UniProtKB)
IEA
GO:0031100
P20248(UniProtKB)
IEA
GO:0033762
P20248(UniProtKB)
IEA
GO:0036120
P20248(UniProtKB)
IEA
GO:0044320
P20248(UniProtKB)
IEA
GO:0045893
P20248(UniProtKB)
IEA
GO:0048146
P20248(UniProtKB)
IEA
GO:0051301
P20248(UniProtKB)
IEA
GO:0071314
P20248(UniProtKB)
IEA
GO:0071373
P20248(UniProtKB)
IEA
GO:0071392
P20248(UniProtKB)
IEA
GO:0071456
P20248(UniProtKB)
IEA
GO:0071732
P20248(UniProtKB)
IEA
GO:0090102
P20248(UniProtKB)
IEA
GO:1990314
P20248(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CCNA2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Peripheral Neuropathy 0.12 1 0 CTD_human
Intellectual Disability 0.12 1 0 CTD_human
Diabetes Mellitus, Experimental 0.08 1 0 RGD
Myocardial Infarction 0.08 1 0 RGD
Mammary Neoplasms 0.008173051 3 0 LHGDN
Liver carcinoma 0.00408156 6 0 BeFree_LHGDN
Adenocarcinoma 0.00272435 1 0 LHGDN
Barrett Esophagus 0.00272435 1 0 LHGDN
Fibrosis 0.00272435 1 0 LHGDN
Giant Cell Tumors 0.00272435 1 0 LHGDN
Mixed Salivary Gland Tumor 0.00272435 1 0 LHGDN
Stomach Neoplasms 0.00272435 1 0 LHGDN
Ganglioglioma 0.00272435 1 0 LHGDN
Malformations of Cortical Development 0.00272435 1 0 LHGDN
Precursor Cell Lymphoblastic Leukemia Lymphoma 0.00272435 1 0 LHGDN
Malignant neoplasm of breast 0.002714419 10 0 BeFree
Carcinogenesis 0.002714419 10 0 BeFree
Malignant neoplasm of lung 0.002638474 2 0 BeFree_GAD
Malignant neoplasm of ovary 0.002638474 2 0 BeFree_GAD
Breast Carcinoma 0.002442977 9 0 BeFree
Malignant neoplasm of urinary bladder 0.002367032 1 0 GAD
Chronic Obstructive Airway Disease 0.002367032 1 0 GAD
Hepatitis B 0.001085767 4 0 BeFree
Ischemia 0.001085767 4 0 BeFree
Renal Cell Carcinoma 0.000814326 3 0 BeFree
leukemia 0.000814326 3 0 BeFree
Neoplasm Metastasis 0.000814326 3 0 BeFree
Glioblastoma 0.000542884 2 0 BeFree
Primary malignant neoplasm of liver 0.000542884 2 0 BeFree
Malignant neoplasm of stomach 0.000542884 2 0 BeFree
Multiple Myeloma 0.000542884 2 0 BeFree
Osteosarcoma 0.000542884 2 0 BeFree
Retinal Diseases 0.000542884 2 0 BeFree
Fibrosis, Liver 0.000542884 2 0 BeFree
Sepsis 0.000542884 2 0 BeFree
Osteosarcoma of bone 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Stomach Carcinoma 0.000542884 2 0 BeFree
Invasive breast carcinoma 0.000542884 2 0 BeFree
Arteriosclerosis 0.000271442 1 0 BeFree
Rheumatoid Arthritis 0.000271442 1 0 BeFree
Atherosclerosis 0.000271442 1 0 BeFree
Bone Diseases 0.000271442 1 0 BeFree
Malignant tumor of colon 0.000271442 1 0 BeFree
Non-Small Cell Lung Carcinoma 0.000271442 1 0 BeFree
Carcinoma, Transitional Cell 0.000271442 1 0 BeFree
Colorectal Neoplasms 0.000271442 1 0 BeFree
Endometriosis 0.000271442 1 0 BeFree
Heart Diseases 0.000271442 1 0 BeFree
Atrial Septal Defects 0.000271442 1 0 BeFree
Herpes Simplex Infections 0.000271442 1 0 BeFree
Leukemia, Myelocytic, Acute 0.000271442 1 0 BeFree
Acute Promyelocytic Leukemia 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Monoclonal Gammopathy of Undetermined Significance 0.000271442 1 0 BeFree
Myocarditis 0.000271442 1 0 BeFree
Nephroblastoma 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
Retinopathy of Prematurity 0.000271442 1 0 BeFree
Systemic Scleroderma 0.000271442 1 0 BeFree
Hepatic necrosis 0.000271442 1 0 BeFree
Congenital heart disease 0.000271442 1 0 BeFree
Proliferative diabetic retinopathy 0.000271442 1 0 BeFree
Embryonal Carcinoma 0.000271442 1 0 BeFree
Renal Pelvis and Ureter Urothelial Carcinoma 0.000271442 1 0 BeFree
Liver and Intrahepatic Biliary Tract Carcinoma 0.000271442 1 0 BeFree
Restenosis 0.000271442 1 0 BeFree
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse 0.000271442 1 0 BeFree
Adenocarcinoma of colon 0.000271442 1 0 BeFree
Malignant neoplasm of liver 0.000271442 1 0 BeFree
Vulval intraepithelial neoplasia 0.000271442 1 0 BeFree
Multiple malignancy 0.000271442 1 0 BeFree
Ischemic cardiomyopathy 0.000271442 1 0 BeFree
Malignant neoplasm of prostate 0.000271442 1 0 BeFree
Endometrial Carcinoma 0.000271442 1 0 BeFree
Colon Carcinoma 0.000271442 1 0 BeFree
Cardiomyopathies 0.000271442 1 0 BeFree
ovarian neoplasm 0.000271442 1 0 BeFree
Chronic inflammatory disorder 0.000271442 1 0 BeFree
Smoldering myeloma 0.000271442 1 0 BeFree
androgen independent prostate cancer 0.000271442 1 0 BeFree
Idiopathic Pulmonary Fibrosis 0.000271442 1 0 BeFree
Asymptomatic multiple myeloma 0.000271442 1 0 BeFree
Early Hepatocellular Carcinoma 0.000271442 1 0 BeFree
Inflammatory cardiomyopathy 0.000271442 1 0 BeFree
Experimental Organism Basal Cell Carcinoma 0.000271442 1 0 BeFree

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