CBX3(chromobox homolog 3) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

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基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

7p15.2
基因染色体位置图

基因简述

基因简述

At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]

[中文简述(自动翻译):]  在核膜，核纤层和异是邻近内核膜。由该基因编码的蛋白结合的DNA和是异的一个组成部分。这种蛋白也可以结合拉明B受体，在内核膜中发现的完整的膜蛋白。所编码的蛋白质的双重结合功能可以解释异的与内核膜的关联。这种蛋白质结合的赖氨酸9甲基化位点组蛋白H3的尾巴。这种蛋白也招募到的紫外线诱导的DNA损伤和双链断裂站点。两个转录变异体编码相同的蛋白质，但在5‘UTR不同，已发现了这种基因。[由RefSeq的，2011年3月提供]

OMIM数据库中对CBX3基因的介绍     Wikipedia数据库中对CBX3基因的介绍

基因序列

基因序列

CBX3基因的碱基序列：[NCBI]

基因突变

基因突变

CBX3基因的碱基突变：           显示全部snp
rs7186       rs2288561       rs2288562       rs2391265       rs3735554       rs3757667       rs3757668       rs3757671       rs3757672       rs5883019       rs6949939       rs6955003       rs7793815       rs7793849       rs9768418       rs9768454       rs9769357       rs9769954       rs10085828       rs10156063       rs10233641       rs10247665       rs10277455       rs10279800       rs11554894       rs11971676       rs11972057       rs11979254       rs11981735       rs12532361       rs12672942       rs13230913       rs13238876       rs16870111       rs17153400       rs28407029       rs28519579      
rs35254059       rs36032567       rs55657742       rs56021640       rs56186484       rs70943278       rs70943279       rs73281550       rs73281551       rs73281554       rs73281562       rs73281563       rs73683263       rs73683264       rs74321701       rs75988840       rs76847182       rs76853718       rs77270165       rs77597952       rs77752192       rs78244699       rs78391041       rs78856917       rs79395803       rs79477886       rs79501180       rs79503307       rs79898568       rs80001940       rs80352496       rs111259750       rs111382546       rs111761581       rs111871239       rs111891412       rs111907229       rs112074869       rs112412904       rs112485832       rs112928113       rs113133824       rs113532000       rs113618008       rs113632993       rs113844882       rs113945730       rs113950013       rs114229557       rs114505254       rs114889109       rs115044286       rs115053938       rs115094732       rs115238999       rs115725846       rs115829318       rs116146970       rs116668835       rs116947159       rs117091957       rs117232097       rs117264396       rs117565979       rs117641933       rs117723070       rs117802671       rs118013246       rs118066525       rs118125475       rs137887285       rs138249007       rs138567018       rs138775659       rs138800614       rs138832599       rs139005383       rs139015469       rs139133255       rs139661119       rs139872420       rs140154884       rs140324309       rs140557242       rs140575524       rs140718854       rs140809582       rs141024126       rs141628788       rs141646491       rs141871278       rs141925857       rs141936134       rs142267744       rs142537315       rs142550836       rs142685680       rs142847133       rs143224601       rs143272288       rs143604069       rs143670407       rs143791073       rs144342176       rs144437057       rs144581757       rs145178503       rs145395285       rs145872193       rs145972943       rs146346849       rs146854300       rs147214544       rs147791694       rs148042933       rs148411396       rs148438009       rs149218467       rs149594731       rs149908387       rs150070836       rs150452989       rs150547103       rs150719027       rs151101852       rs180956892       rs181215176       rs181300726       rs181370157       rs181537806       rs181865277       rs181904482       rs182290639       rs182369741       rs182377644       rs182421248       rs182585378       rs182708029       rs183208055       rs183586982       rs183714575       rs183952353       rs184151588       rs184267440       rs184550155       rs184577418       rs184581869       rs184720192       rs184967893       rs185090224       rs185328561       rs185405929       rs186029408       rs186247543       rs186263580       rs186759051       rs186820821       rs186877501       rs187435406       rs187778922       rs187827370       rs188086092       rs188244976       rs188633021       rs188703145       rs188757407       rs188822196       rs188896172       rs189258793       rs189467571       rs189527838       rs189561275       rs189796414       rs190293844       rs190297137       rs190520743       rs190942692       rs191109734       rs191206664       rs191280706       rs191342675       rs191357884       rs191785721       rs191976883       rs192219048       rs192479687       rs192714146       rs192837231       rs192881539       rs199646600       rs200014310       rs200128779       rs200166027       rs200410047       rs200600284       rs200791010       rs201005996       rs201165333       rs201557283       rs201575603       rs202084579       rs202161524       rs367780574       rs368201219       rs368394999       rs368584614       rs368955032       rs369210080       rs369332718       rs369857587       rs369884481       rs370029780       rs370499819       rs370877360       rs371590498       rs372000704       rs372035189       rs372413972       rs372464446       rs372560427       rs372622465       rs372721894       rs372760990       rs372876793       rs372921828       rs373262978       rs373331689       rs373816861       rs374505442       rs374663838       rs375282406       rs375625389       rs375902099       rs375914282       rs376381300       rs376487206       rs376571594       rs376630956       rs376924238       rs377228409       rs527294636       rs527418017       rs527908616       rs528024567       rs528248270       rs528360863       rs528486286       rs528559019       rs528737309       rs528850554       rs528894978       rs529200935       rs529241478       rs529462460       rs529472443       rs529507561       rs529576160       rs529833280       rs530013959       rs530051425       rs530114160       rs530117129       rs530415141       rs530419495       rs530652812       rs530735681       rs530804358       rs530942916       rs531053552       rs531210376       rs531336951       rs531812893       rs531897227       rs531901975       rs531909260       rs532023444       rs532214410       rs532339891       rs532375363       rs532376553       rs532406990       rs532647271       rs532832984       rs532950916       rs532997721       rs533155794       rs533243204       rs533542924       rs533636446       rs534152383       rs534275369       rs534280361       rs534365488       rs534373592       rs534484135       rs534519771       rs534591703       rs534788088       rs534865104       rs534886735       rs534899639       rs535080177       rs535267864       rs535298845       rs535454513       rs535527230       rs535662869       rs535725584       rs535748605       rs535758118       rs535995523       rs536098431       rs536158771       rs536325264       rs536359656       rs536599038       rs536614209       rs536729236       rs536813566       rs536856982       rs537093787       rs537161081       rs537198518       rs537328604       rs537408192       rs537509790       rs537520116       rs537693274       rs538137745       rs538193195       rs538280773       rs538356956       rs538498956       rs538561730       rs538696426       rs538815981       rs538989496       rs539071538       rs539101950       rs539345515       rs539412704       rs539481375       rs539497722       rs539525095       rs539615297       rs539653491       rs539726420       rs539729557       rs540177563       rs540255874       rs540482624       rs540482661       rs540502792       rs540585296       rs540674041       rs540717937       rs540866352       rs541058585       rs541141900       rs541694472       rs541774780       rs541861090       rs541931816       rs541986335       rs542794415       rs543171866       rs543273759       rs543288919       rs543343409       rs543357291       rs543438090       rs543513408       rs543522649       rs543608737       rs543700760       rs543900752       rs543917453       rs544112485       rs544233757       rs544395963       rs544410579       rs544423595       rs544563324       rs544709672       rs544726979       rs544958556       rs545579038       rs545662478       rs545666453       rs545754169       rs545866076       rs546049938       rs546204428       rs546227209       rs546274708       rs546499173       rs546654277       rs546683968       rs546778885       rs546938130       rs546981912       rs547048478       rs547112525       rs547168397       rs547172614       rs547542587       rs547580717       rs547838130       rs547853175       rs547874016       rs547976914       rs548007688       rs548075928       rs548110391       rs548289201       rs548471329       rs549026572       rs549029670       rs549302502       rs549416869       rs549563127       rs549744099       rs549936180       rs550222847       rs550228313       rs550631962       rs550708821       rs550761204       rs550798350       rs550872875       rs550917113       rs551048987       rs551403150       rs551798317       rs551806094       rs551836988       rs551907984       rs551990185       rs552127686       rs552334603       rs552922553       rs553001708       rs553106002       rs553141622       rs553215147       rs553660829       rs553912628       rs554197268       rs554207062       rs554309670       rs554318585       rs554355215       rs554412791       rs554449577       rs554525807       rs554530939       rs555123976       rs555300910       rs555396062       rs555454055       rs555606857       rs555802564       rs555992869       rs556012006       rs556029542       rs556050161       rs556080441       rs556194884       rs556357724       rs557067252       rs557068940       rs557201539       rs557244253       rs557304664       rs557646271       rs557853907       rs557967491       rs558168019       rs558254000       rs558256395       rs558437773       rs558509108       rs558543587       rs558808955       rs559185651       rs559297701       rs559297760       rs559358878       rs559365534       rs559457704       rs559626535       rs559639000       rs559840314       rs559907152       rs560344866       rs560368423       rs560476367       rs560649713       rs560691557       rs561094204       rs561376303       rs561733435       rs561756374       rs562220988       rs562609472       rs562807847       rs562824416       rs563053656       rs563082690       rs563164402       rs563219634       rs563231932       rs563244637       rs563325696       rs563371614       rs563400163       rs563687492       rs563802670       rs563818011       rs563840184       rs563860877       rs563983354       rs564310108       rs564419880       rs564591519       rs564615424       rs564809666       rs564871677       rs564905361       rs565160187       rs565392435       rs565455800       rs565555916       rs565626917       rs565663654       rs565672843       rs565791139       rs565879825       rs566121293       rs566588604       rs566601320       rs566739502       rs566816058       rs567114694       rs567182254       rs567613645       rs567649697       rs567806647       rs567967488       rs568043681       rs568072230       rs568198570       rs568530380       rs568573942       rs568817931       rs568820769       rs568908392       rs569181374       rs569339011       rs569411317       rs569495722       rs569536839       rs569584417       rs569606982       rs569648461       rs570094820       rs570098706       rs570477508       rs570591008       rs570803331       rs570840086       rs571205137       rs571359419       rs571562692       rs571628520       rs571673313       rs571680493       rs571686331       rs571794216       rs571920233       rs572000719       rs572413925       rs572700048       rs572933554       rs572966340       rs573004577       rs573160144       rs573247307       rs573322129       rs573879052       rs573890030       rs573901028       rs574290972       rs574373697       rs574462316       rs574469349       rs574579244       rs574759608       rs575001172       rs575028529       rs575065667       rs575108350       rs575109916       rs575255428       rs575617958       rs575635789       rs575647352       rs575797483       rs575805413       rs575808040       rs575922978       rs575959807       rs576173198       rs576314334       rs576678371       rs576730581       rs576789570       rs576833016       rs576860321       rs577035399       rs577143001       rs577381042       rs577493254       rs577762508       rs578056443       rs578139828       rs578165440       rs745666259       rs745745464       rs745949209       rs746229930       rs746387846       rs746557261       rs746627330       rs746686796       rs746804235       rs747054756       rs747643126       rs747661278       rs747695069       rs747704314       rs747954852       rs748257690       rs748426965       rs748552169       rs749336313       rs749477806       rs749669569       rs749984703       rs750059523       rs750171741       rs750238315       rs750539865       rs750652310       rs750818911       rs750979706       rs751022345       rs751134339       rs751559785       rs751634866       rs751693245       rs751767454       rs751862497       rs752332120       rs752508670       rs752852652       rs753307021       rs753665991       rs753824971       rs753943134       rs754842375       rs754927630       rs755610639       rs755762446       rs755853094       rs755932262       rs755973845       rs756577908       rs756638023       rs756702887       rs757066251       rs757490264       rs757524224       rs757674203       rs757690570       rs757898551       rs758225153       rs758862262       rs758980737       rs759188575       rs759296306       rs759917188       rs760321538       rs760636512       rs760770510       rs761717953       rs761876785       rs762011516       rs762146098       rs762553190       rs762628517       rs762704799       rs762818575       rs762822118       rs763173135       rs763426427       rs763502231       rs763596820       rs763740327       rs763936052       rs764002292       rs764094445       rs764315652       rs764317451       rs764405458       rs764726411       rs764927854       rs765061985       rs765471385       rs765558045       rs765839751       rs765959395       rs766045487       rs766495519       rs766630755       rs766908720       rs767087967       rs767121792       rs767568353       rs767779702       rs767821675       rs768198099       rs768288217       rs768605300       rs768825479       rs768869344       rs768878661       rs769187448       rs769212843       rs769275453       rs769756418       rs769903763       rs769942392       rs770266352       rs770320418       rs770410400       rs770801413       rs770843081       rs771008947       rs771247002       rs771351914       rs771446834       rs771547915       rs772030902       rs772125116       rs772240792       rs772403539       rs772667673       rs772797729       rs773511953       rs773527822       rs773812435       rs773826070       rs774040447       rs774507846       rs774977820       rs775005053       rs775068117       rs775077746       rs775850433       rs776038560       rs776117134       rs776123337       rs776140361       rs776205408       rs776489024       rs776648455       rs776811915       rs777095115       rs777446751       rs777667765       rs778109690       rs778150747       rs778244272       rs778816351       rs778834492       rs779064259       rs779243081       rs779381861       rs779666542       rs779867839       rs779939069       rs780011395       rs780028680       rs780117410       rs780811182       rs780891120       rs781051786       rs781287189       rs781351620       rs781643434       rs76847182       rs568908392      

基因表达

基因表达

CBX3基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TAACTCTCAGAAAGCTGGCA
59
CTCGTTTCCTCATAGCATCTC
58
CTGAAGTGGAAGGGATTTACAG
59
GGTTTGTCAGCAGCATCTC
59
GAGATGCTGCTGACAAACC
59
CATCAATTCTCCACTGCTGTC
59
AAGTACTAGATCGACGTGTAGTG
60
CCCAAGTATTGTCAGCATCTG
59
AACTCTCAGAAAGCTGGCA
59
GGTTTGTCAGCAGCATCTC
59
GAGATGCTGCTGACAAACC
59
CATCAATTCTCCACTGCTGTC
59
AGTACTAGATCGACGTGTAGTG
59
CCCAAGTATTGTCAGCATCTG
59
TAACTCTCAGAAAGCTGGCA
59
GGTTTGTCAGCAGCATCTC
59
GAGATGCTGCTGACAAACC
59
CAATTCTCCACTGCTGTCTG
59
ATTTCCTGAAGTGGAAGGGA
59
GGTTTGTCAGCAGCATCTC
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CBX3基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CBX3基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000775
Q13185(UniProtKB)
IDA
GO:0000779
Q13185(UniProtKB)
ISS
GO:0000784
Q13185(UniProtKB)
IDA
GO:0000785
Q13185(UniProtKB)
IDA
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005515
Q13185(UniProtKB)
IPI
GO:0005634
Q13185(UniProtKB)
IDA
GO:0005634
Q13185(UniProtKB)
IDA
GO:0005635
Q13185(UniProtKB)
ISS
GO:0005637
Q13185(UniProtKB)
NAS
GO:0005719
Q13185(UniProtKB)
IDA
GO:0005720
Q13185(UniProtKB)
IDA
GO:0005819
Q13185(UniProtKB)
IDA
GO:0006338
Q13185(UniProtKB)
NAS
GO:0006351
Q13185(UniProtKB)
IEA
GO:0019899
Q13185(UniProtKB)
IPI
GO:0019904
Q13185(UniProtKB)
IPI
GO:0019904
Q13185(UniProtKB)
IPI
GO:0031618
Q13185(UniProtKB)
ISS
GO:0035985
Q13185(UniProtKB)
IEA
GO:0042802
Q13185(UniProtKB)
IPI
GO:0042802
Q13185(UniProtKB)
IPI
GO:0045892
Q13185(UniProtKB)
IDA
GO:0045892
Q13185(UniProtKB)
IMP
GO:0048511
Q13185(UniProtKB)
IEA
GO:0071549
Q13185(UniProtKB)
IEA
GO:1990226
Q13185(UniProtKB)
IPI
GO:0005634
S4R2Y4(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CBX3基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Precancerous Conditions 0.000271442 1 0 BeFree
Seminoma 0.000271442 1 0 BeFree
Teratoma 0.000271442 1 0 BeFree
Adenocarcinoma of lung (disorder) 0.000271442 1 0 BeFree
Embryonal Carcinoma 0.000271442 1 0 BeFree
Malignant neoplasm of lung 0.000271442 1 0 BeFree
Dyskeratosis Congenita 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Carcinoma of lung 0.000271442 1 0 BeFree
Localized Malignant Neoplasm 0.000271442 1 0 BeFree
High-Grade Prostatic Intraepithelial Neoplasia 0.000271442 1 0 BeFree
Invasive Carcinoma 0.000271442 1 0 BeFree
Localized Carcinoma 0.000271442 1 0 BeFree

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