CBR1(carbonyl reductase 1)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

21q22.1
基因染色体位置图

基因简述

基因简述

The protein encoded by this gene belongs to the short-chain dehydrogenases/reductases (SDR) family, which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds, such as quinones, prostaglandins, and various xenobiotics. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2013]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于短链脱氢酶/还原酶（SDR）家族，其作为具有羰基的化合物，如醌，前列腺素和各种各样的异生素宽特异性NADPH依赖性氧化还原酶。另外剪接转录变体也发现了这种基因。 [由RefSeq的，2013年11月提供]

OMIM数据库中对CBR1基因的介绍     Wikipedia数据库中对CBR1基因的介绍

基因序列

基因序列

CBR1基因的碱基序列：[NCBI]

基因突变

基因突变

CBR1基因的碱基突变：           显示全部snp
rs9024       rs20572       rs25678       rs998383       rs998384       rs1005111       rs1005694       rs1005695       rs1005696       rs1051543       rs1143663       rs2156406       rs2230191       rs2230192       rs2239859       rs2282500       rs2835265       rs2835266       rs3761354       rs3787726       rs3787728       rs5031013       rs6517327       rs6517328       rs9979814       rs9979957       rs11542168       rs34966276       rs35710857       rs41540212       rs41540715       rs41541813       rs41545115       rs41547112       rs41547416       rs41549312       rs41555214      
rs41556413       rs41557012       rs41557318       rs41563613       rs41563715       rs61759823       rs66638540       rs71196978       rs71330638       rs74484583       rs76413493       rs77573804       rs77642344       rs78058185       rs78554345       rs79905171       rs111862586       rs112597619       rs113287155       rs113589610       rs113888409       rs117272030       rs117302952       rs118126898       rs138094996       rs138602619       rs138635970       rs139372689       rs139773975       rs140103151       rs140395680       rs140432924       rs141259214       rs141295222       rs142412960       rs142777250       rs142778878       rs143175086       rs143215551       rs143566776       rs143775206       rs144194050       rs144439017       rs145472382       rs145765154       rs145767436       rs145871542       rs146234708       rs146559297       rs146570341       rs146758729       rs146879523       rs147149788       rs147159525       rs147519087       rs148056908       rs148205009       rs148759829       rs148867169       rs149334090       rs149755706       rs150206324       rs150365005       rs151043730       rs151101410       rs151318439       rs181425919       rs181553429       rs184407703       rs184719814       rs184806783       rs185960235       rs187761572       rs187807472       rs188402407       rs189271366       rs190160512       rs190589221       rs190861031       rs191556963       rs192717129       rs199906618       rs199962768       rs200192508       rs200223739       rs200408186       rs200615385       rs200695117       rs201334038       rs367743996       rs367857649       rs368199856       rs368608178       rs369228069       rs370632546       rs371089618       rs372571793       rs372726650       rs373092056       rs374191813       rs374271544       rs374414411       rs375697371       rs375784875       rs377102490       rs377569583       rs377645409       rs527619468       rs528673956       rs528721284       rs529746829       rs529825233       rs530322864       rs531140419       rs531545108       rs531633735       rs532271051       rs532348271       rs532685207       rs532865639       rs533241717       rs533248981       rs533716973       rs533734780       rs533864137       rs536331017       rs536811305       rs537530000       rs538134131       rs538821711       rs539224993       rs539890750       rs540101066       rs540183337       rs540823495       rs540946186       rs542811393       rs543054967       rs543716349       rs543800905       rs544001639       rs545112934       rs545432870       rs546119820       rs547110636       rs547298430       rs547398468       rs547794915       rs547877552       rs548000952       rs549280485       rs551377365       rs551669978       rs551908350       rs553204640       rs554248175       rs555028304       rs555114306       rs555328020       rs555473871       rs555514457       rs556184158       rs556896935       rs557925178       rs558437905       rs558896125       rs559267091       rs559448728       rs559624284       rs559844148       rs561020560       rs561254689       rs562522086       rs563909657       rs564684300       rs565147045       rs565597795       rs566117000       rs566205268       rs566479893       rs567412104       rs569886457       rs570206837       rs570886906       rs571566347       rs571954075       rs572763511       rs572847319       rs573951298       rs574515402       rs575118509       rs576524713       rs576964020       rs577105555       rs577749943       rs577840104       rs745481191       rs745656182       rs745672468       rs745692534       rs745950206       rs746216247       rs746336766       rs746699955       rs746822383       rs747107090       rs747389864       rs747591615       rs747665855       rs747881279       rs748123541       rs748129973       rs748156211       rs748300804       rs748338970       rs748473499       rs748541874       rs749029472       rs749119317       rs749509888       rs749558223       rs749690236       rs750434431       rs750436391       rs750689007       rs750938300       rs751141827       rs751302216       rs751331798       rs751602193       rs751633352       rs751812271       rs751827580       rs751952306       rs751985377       rs752049883       rs752113715       rs752394402       rs752649052       rs752970795       rs753192675       rs753341514       rs753541598       rs753663954       rs753856533       rs753889721       rs753977576       rs754253094       rs754600918       rs754618077       rs754702330       rs754868460       rs755019249       rs755543091       rs755677201       rs756161777       rs756250127       rs756683447       rs756729740       rs756819923       rs756821807       rs757086930       rs757208303       rs757294585       rs757494065       rs757911931       rs758058719       rs758236840       rs758328503       rs758492946       rs758678387       rs758768231       rs759097808       rs759118392       rs759316194       rs759348201       rs759352463       rs759475325       rs759878913       rs759895370       rs759895472       rs760237383       rs760249754       rs760263509       rs760444957       rs760456856       rs760643033       rs760841760       rs761398228       rs761407628       rs761599903       rs762056579       rs762177714       rs762469755       rs762501525       rs762808256       rs762932134       rs762942037       rs763111396       rs763204071       rs763329185       rs763443448       rs763727671       rs763742012       rs763746901       rs763855338       rs763917680       rs763917846       rs764197380       rs764687472       rs764885114       rs764936035       rs765126870       rs765253793       rs765270229       rs765482677       rs765787444       rs765843052       rs766413880       rs766432246       rs766572624       rs766693597       rs766768951       rs766890559       rs766929443       rs767338903       rs767375288       rs767383110       rs767860146       rs767914019       rs768453981       rs768515405       rs768603380       rs768922674       rs768928349       rs768953939       rs769114657       rs769401188       rs769526133       rs770036984       rs770198762       rs770734212       rs770896302       rs771180650       rs771357179       rs771751330       rs772044820       rs772053364       rs772097439       rs772480635       rs772592919       rs772652346       rs772797612       rs772888706       rs773365505       rs773560089       rs773738111       rs773828531       rs774277249       rs774437766       rs774636988       rs775082435       rs775176170       rs775470312       rs775491534       rs775778302       rs775837893       rs775955102       rs776354083       rs776655522       rs776688059       rs777221378       rs777409910       rs777670435       rs777679109       rs778116397       rs778239233       rs778356342       rs778680682       rs778704295       rs779074269       rs779228807       rs779368600       rs779831065       rs779948695       rs779953785       rs780185893       rs780387171       rs780496525       rs780517742       rs780692500       rs780703439       rs781084203       rs781208993       rs781536281       rs781553870       rs781647021       rs781715120       rs869145162      

基因表达

基因表达

CBR1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CTTCAAGGTTGCTGATCCC
59
GGGAGTAATTCTGTGCACAC
59
CCTTCAAGGTTGCTGATCC
59
GGGAGTAATTCTGTGCACAC
59
ATTCAAGCTGAAGTGACGA
57
TAGAAGTAGCACAACTTGGG
57
CTTCAAGGTTGCTGATCCC
59
GGGAGTAATTCTGTGCACAC
59
CTTCAAGGTTGCTGATCCC
59
GAGGGAGTAATTCTGTGCAC
58
ATTCAAGCTGAAGTGACGA
57
ATGGCACATATCAGCTTGG
58
CCTTCAAGGTTGCTGATCC
59
GGGAGTAATTCTGTGCACAC
59
CTTCAAGGTTGCTGATCCC
59
GAGGGAGTAATTCTGTGCAC
58
CTTCAAGGTTGCTGATCCC
59
GAGGGAGTAATTCTGTGCAC
58
TATTCAAGCTGAAGTGACGA
57
AGAAGTAGCACAACTTGGG
57

转录因子

转录因子

      尚未收录相关数据

基因本体信息

CBR1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

CBR1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0004090
P16152(UniProtKB)
IDA
GO:0005829
P16152(UniProtKB)
TAS
GO:0016655
P16152(UniProtKB)
IDA
GO:0017144
P16152(UniProtKB)
IDA
GO:0019371
P16152(UniProtKB)
TAS
GO:0030855
P16152(UniProtKB)
IEP
GO:0042373
P16152(UniProtKB)
IDA
GO:0047021
P16152(UniProtKB)
IEA
GO:0050221
P16152(UniProtKB)
TAS
GO:0055114
P16152(UniProtKB)
IDA
GO:0070062
P16152(UniProtKB)
IDA
GO:0070062
P16152(UniProtKB)
IDA
GO:0070062
P16152(UniProtKB)
IDA
GO:0070062
P16152(UniProtKB)
IDA
GO:1903561
P16152(UniProtKB)
IDA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控CBR1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Down Syndrome 0.120814326 4 0 BeFree_CTD_human
Liver carcinoma 0.120542884 2 0 BeFree_CTD_human
Colonic Neoplasms 0.120271442 2 0 BeFree_CTD_human
Cardiomyopathies 0.120271442 2 0 BeFree_CTD_human
Prostatic Neoplasms 0.12 1 0 CTD_human
Muscle Weakness 0.12 1 0 CTD_human
Dermatitis, Irritant 0.12 1 0 CTD_human
Diabetes Mellitus, Experimental 0.08 1 0 RGD
Mammary Neoplasms 0.005091382 2 0 GAD_LHGDN
Malignant neoplasm of breast 0.003724241 6 0 BeFree_GAD
Malignant neoplasm of lung 0.003452799 5 1 BeFree_GAD
Malignant neoplasm of urinary bladder 0.002367032 1 0 GAD
Chronic Obstructive Airway Disease 0.002367032 1 0 GAD
Osteoarthropathy, Primary Hypertrophic 0.001900093 7 0 BeFree
Colorectal Carcinoma 0.001357209 5 0 BeFree
Breast Carcinoma 0.001357209 5 0 BeFree
Malignant tumor of colon 0.001085767 4 0 BeFree
Malignant neoplasm of stomach 0.001085767 4 0 BeFree
Carcinoma of lung 0.001085767 4 1 BeFree
Colon Carcinoma 0.001085767 4 0 BeFree
Stomach Carcinoma 0.001085767 4 0 BeFree
Colorectal Cancer 0.001085767 4 0 BeFree
Carcinogenesis 0.000814326 3 0 BeFree
Ulcerative Colitis 0.000542884 2 0 BeFree
Leukemia, Myelocytic, Acute 0.000542884 2 0 BeFree
Neoplasm Metastasis 0.000542884 2 0 BeFree
Tumor Progression 0.000542884 2 0 BeFree
Diabetes Mellitus, Insulin-Dependent 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Pulmonary Hypertension 0.000271442 1 0 BeFree
leukemia 0.000271442 1 0 BeFree
Acute Promyelocytic Leukemia 0.000271442 1 0 BeFree
Ovarian Carcinoma 0.000271442 1 0 BeFree
polyps 0.000271442 1 0 BeFree
Tuberous Sclerosis 0.000271442 1 0 BeFree
Ureteral obstruction 0.000271442 1 0 BeFree
Small cell carcinoma of lung 0.000271442 1 1 BeFree
Cholangiocarcinoma 0.000271442 1 0 BeFree
Medullary carcinoma of thyroid 0.000271442 1 0 BeFree
Carcinoma, Small Cell 0.000271442 1 1 BeFree
Clubbing of nail 0.000271442 1 0 BeFree
Absence of sensation 0.000271442 1 0 BeFree
Malignant Childhood Neoplasm 0.000271442 1 1 BeFree
Helicobacter pylori (H. pylori) infection in conditions classified elsewhere and of unspecified site 0.000271442 1 0 BeFree
Cortical Dysplasia 0.000271442 1 0 BeFree
Malignant neoplasm of gastrointestinal tract 0.000271442 1 0 BeFree
Drug Resistant Epilepsy 0.000271442 1 0 BeFree
Malignant neoplasm of ovary 0.000271442 1 0 BeFree
Partial Trisomy 0.000271442 1 0 BeFree
Malformations of Cortical Development 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

没有相关文献

基因相关服务

基因相关服务

基因评论

基因评论

我要说两句
热门评论
还没有评论，赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话： 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码，关注微信订阅号，实时查看信息，关注医学生物学动态。

版权所有 © 2016.Genelibs 济南弘晖生物技术有限公司 鲁ICP备13024435号-2