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BRDT is similar to the RING3 protein family. It possesses 2 bromodomain motifs and a PEST sequence (a cluster of proline, glutamic acid, serine, and threonine residues), characteristic of proteins that undergo rapid intracellular degradation. The bromodomain is found in proteins that regulate transcription. Several transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Jun 2011]
[中文简述(自动翻译):]  BRDT类似于RING3蛋白家族。它具有2溴区基序和一个PEST序列(脯氨酸,谷氨酸,丝氨酸和苏氨酸残基簇),它经历快速细胞内降解的蛋白质的特性。该布罗莫是在调节转录蛋白质中。已发现该基因编码多种亚型几个抄本变形。 [由RefSeq的,2011年6月提供]
BRDT基因(以及对应的蛋白质)的细胞分布位置:
BRDT基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Azoospermia | 0.002638474 | 2 | 0 | BeFree_GAD |
Oligospermia | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Subfertility | 0.000271442 | 1 | 0 | BeFree |
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