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This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  该基??因编码属于RAF / MIL家庭丝氨酸/苏氨酸蛋白激酶的蛋白质。这种蛋白质在调节MAP激酶/ ERK的信号传导途径,从而影响细胞分裂,分化,和分泌的作用。在这个基因的突变与心脸皮肤综合征,这种疾病的特点是心脏畸形,智力低下及鲜明的面容有关。在这个基因的突变也已与各种癌症,包括非何杰金氏淋巴瘤,结肠直肠癌,恶性黑素瘤,甲状腺癌,非小细胞肺癌和肺腺癌相关联。假基因,位于X染色体上,已经确定了这个基因。 [由RefSeq的,2008年7月提供]
BRAF基因(以及对应的蛋白质)的细胞分布位置:
BRAF基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Cardio-facio-cutaneous syndrome | 0.567057489 | 30 | 29 | BeFree_CLINVAR_CTD_human_MGD_ORPHANET_UNIPROT |
melanoma | 0.430771416 | 851 | 6 | BeFree_CLINVAR_CTD_human_GAD_LHGDN |
NOONAN SYNDROME 7 | 0.36 | 2 | 14 | CLINVAR_CTD_human_UNIPROT |
LEOPARD SYNDROME 3 | 0.36 | 1 | 1 | CLINVAR_CTD_human_UNIPROT |
Papillary thyroid carcinoma | 0.324734064 | 348 | 3 | BeFree_CLINVAR_GAD_ORPHANET |
Thyroid Neoplasm | 0.288143256 | 101 | 1 | BeFree_CTD_human_GAD_LHGDN |
Colorectal Cancer | 0.274375073 | 298 | 2 | BeFree_GAD_UNIPROT |
Noonan Syndrome | 0.248458305 | 9 | 0 | BeFree_CTD_human_GAD_ORPHANET |
Adenocarcinoma of lung (disorder) | 0.243528744 | 13 | 3 | BeFree_CLINVAR_CTD_human |
Lymphoma, Non-Hodgkin | 0.242367032 | 3 | 3 | CLINVAR_GAD_UNIPROT |
LEOPARD Syndrome | 0.240814326 | 3 | 2 | BeFree_CLINVAR_ORPHANET |
Craniopharyngioma | 0.240271442 | 1 | 1 | BeFree_CTD_human_ORPHANET |
Colorectal Neoplasms | 0.215741083 | 57 | 1 | BeFree_CTD_human_GAD_LHGDN |
Microsatellite Instability | 0.153138448 | 15 | 0 | CTD_human_GAD |
Carcinogenesis | 0.143886885 | 88 | 1 | BeFree_CTD_human |
Colon Carcinoma | 0.135472187 | 57 | 7 | BeFree_CLINVAR |
Pilocytic Astrocytoma | 0.133572094 | 50 | 1 | BeFree_ORPHANET |
Hairy Cell Leukemia | 0.131672 | 43 | 3 | BeFree_ORPHANET |
Astrocytoma | 0.131615919 | 17 | 1 | BeFree_CTD_human_GAD_LHGDN |
Non-Small Cell Lung Carcinoma | 0.130510288 | 31 | 15 | BeFree_CLINVAR_GAD |
Glioma | 0.129424521 | 28 | 1 | BeFree_CTD_human_GAD |
Lung Neoplasms | 0.127458414 | 3 | 0 | CTD_human_GAD_LHGDN |
Carcinoma of lung | 0.124885954 | 19 | 3 | BeFree_UNIPROT |
Follicular thyroid carcinoma | 0.124071628 | 15 | 2 | BeFree_CLINVAR |
Liver neoplasms | 0.122909916 | 4 | 1 | BeFree_CTD_human_GAD |
Mandibular Neoplasms | 0.122367032 | 2 | 0 | CTD_human_GAD |
Ameloblastoma | 0.121357209 | 5 | 1 | BeFree_CTD_human |
Costello syndrome (disorder) | 0.121357209 | 6 | 0 | BeFree_CTD_human |
Kidney Neoplasm | 0.120542884 | 3 | 1 | BeFree_CTD_human |
Adrenocortical carcinoma | 0.120542884 | 3 | 0 | BeFree_CTD_human |
Neuroendocrine Tumors | 0.120542884 | 3 | 0 | BeFree_CTD_human |
Sezary Syndrome | 0.12 | 1 | 0 | CTD_human |
Lymphoma, T-Cell, Cutaneous | 0.12 | 1 | 0 | CTD_human |
Nonseminomatous germ cell tumor | 0.12 | 0 | 1 | CLINVAR |
Hashimoto-Pritzker syndrome | 0.12 | 0 | 0 | ORPHANET |
Carcinoma, Papillary | 0.08556525 | 61 | 1 | BeFree_GAD_LHGDN |
Colorectal Carcinoma | 0.074103631 | 273 | 2 | BeFree |
Thyroid carcinoma | 0.060151813 | 182 | 2 | BeFree_GAD |
Neoplasm Metastasis | 0.055447544 | 151 | 3 | BeFree_GAD_LHGDN |
Adenocarcinoma | 0.054760159 | 63 | 4 | BeFree_GAD_LHGDN |
Metastatic melanoma | 0.049402421 | 182 | 8 | BeFree |
Colonic Neoplasms | 0.035753177 | 21 | 1 | BeFree_GAD_LHGDN |
Malignant neoplasm of thyroid | 0.032030141 | 118 | 2 | BeFree |
Adenoma | 0.029770186 | 50 | 1 | BeFree_GAD_LHGDN |
Thyroid Nodule | 0.027393223 | 59 | 1 | BeFree_GAD_LHGDN |
Skin Neoplasms | 0.024756087 | 14 | 0 | BeFree_GAD |
Melanocytic nevus | 0.023307782 | 39 | 1 | BeFree_GAD_LHGDN |
polyps | 0.019302167 | 42 | 1 | BeFree_LHGDN |
Malignant tumor of colon | 0.017915164 | 66 | 2 | BeFree |
Secondary malignant neoplasm of lymph node | 0.01737228 | 64 | 1 | BeFree |
Nevus | 0.017250185 | 20 | 1 | BeFree_GAD_LHGDN |
Papillary adenocarcinoma | 0.016569224 | 7 | 0 | GAD |
Neoplasm Invasiveness | 0.016569224 | 7 | 0 | GAD |
Cutaneous Melanoma | 0.016557954 | 61 | 2 | BeFree |
Colorectal cancer metastatic | 0.016286512 | 60 | 1 | BeFree |
ovarian neoplasm | 0.016164417 | 17 | 1 | BeFree_GAD_LHGDN |
Malignant neoplasm of lung | 0.015168407 | 24 | 3 | BeFree_GAD |
Malignant neoplasm of ovary | 0.012182547 | 12 | 1 | BeFree_GAD |
Lymphatic Metastasis | 0.01183516 | 5 | 0 | GAD |
Gastrointestinal Stromal Tumors | 0.011801484 | 16 | 1 | BeFree_GAD_LHGDN |
Squamous cell carcinoma | 0.011530042 | 18 | 0 | BeFree_GAD_LHGDN |
Rectal Neoplasms | 0.010553895 | 7 | 0 | BeFree_GAD |
Hereditary Nonpolyposis Colorectal Cancer | 0.010043349 | 37 | 1 | BeFree |
Hashimoto Disease | 0.009001189 | 9 | 1 | BeFree_GAD |
Anaplastic thyroid carcinoma | 0.007871814 | 29 | 1 | BeFree |
Rectal Carcinoma | 0.007719925 | 11 | 1 | BeFree_GAD |
Hereditary Nonpolyposis Colorectal Neoplasms | 0.007458414 | 3 | 0 | GAD_LHGDN |
Pancreatic Neoplasm | 0.007458414 | 3 | 0 | GAD_LHGDN |
Colonic Polyps | 0.007372538 | 4 | 0 | BeFree_GAD |
Hyperplastic Polyp | 0.007328931 | 27 | 1 | BeFree |
Neoplasm Recurrence, Local | 0.007101096 | 3 | 0 | GAD |
Papillary and follicular adenocarcinoma | 0.007101096 | 3 | 0 | GAD |
Cystadenocarcinoma, Serous | 0.007101096 | 3 | 0 | GAD |
Tumor Progression | 0.007057489 | 26 | 1 | BeFree |
Histiocytosis, Langerhans-Cell | 0.006514605 | 24 | 1 | BeFree |
Precursor Cell Lymphoblastic Leukemia Lymphoma | 0.005720142 | 3 | 0 | BeFree_LHGDN |
Stomach Neoplasms | 0.0054487 | 2 | 0 | LHGDN |
Brain Neoplasms | 0.005352893 | 12 | 1 | BeFree_GAD |
Precancerous Conditions | 0.005276948 | 4 | 1 | BeFree_GAD |
Medullary carcinoma | 0.005276948 | 4 | 0 | BeFree_GAD |
Endometrial Neoplasms | 0.005091382 | 2 | 0 | GAD_LHGDN |
Endometrial Carcinoma | 0.005081451 | 10 | 1 | BeFree_GAD |
Epithelial ovarian cancer | 0.005081451 | 11 | 1 | BeFree_GAD |
Neoplasms, Multiple Primary | 0.004734064 | 2 | 0 | GAD |
Benign melanocytic nevus | 0.004614512 | 17 | 1 | BeFree |
Malignant neoplasm of stomach | 0.004538567 | 9 | 0 | BeFree_GAD |
Ovarian Carcinoma | 0.00434307 | 16 | 1 | BeFree |
Uveal melanoma | 0.00434307 | 16 | 1 | BeFree |
Neurofibromatosis 1 | 0.004267125 | 8 | 1 | BeFree_GAD |
Sarcoma | 0.003800186 | 14 | 1 | BeFree |
Papillary Thyroid Microcarcinoma | 0.003800186 | 14 | 1 | BeFree |
Metastatic malignant neoplasm to brain | 0.003528744 | 13 | 1 | BeFree |
Turcot syndrome (disorder) | 0.003528744 | 13 | 1 | BeFree |
Solid tumour | 0.003528744 | 13 | 1 | BeFree |
Traditional Serrated Adenoma | 0.003528744 | 13 | 1 | BeFree |
Cystadenoma, Serous | 0.003267234 | 2 | 0 | BeFree_LHGDN |
Glioblastoma | 0.003257302 | 12 | 1 | BeFree |
Thyroid Diseases | 0.003181358 | 4 | 1 | BeFree_GAD |
Nasal Polyps | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Epithelioid and spindle cell nevus | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Ganglioglioma | 0.002985861 | 11 | 1 | BeFree |
Erdheim-Chester Disease | 0.002985861 | 11 | 1 | BeFree |
Melanocytic nevus of skin | 0.002985861 | 11 | 1 | BeFree |
Bladder Neoplasm | 0.002909916 | 2 | 0 | BeFree_GAD |
Nodular Goiter | 0.002909916 | 3 | 1 | BeFree_GAD |
Conjunctival Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Mesothelioma | 0.00272435 | 1 | 0 | LHGDN |
Nephrotic Syndrome | 0.00272435 | 1 | 0 | LHGDN |
Pancreatitis | 0.00272435 | 1 | 0 | LHGDN |
Pituitary Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
Angiomyolipoma | 0.00272435 | 1 | 0 | LHGDN |
gliosarcoma | 0.00272435 | 1 | 0 | LHGDN |
Differentiated Thyroid Gland Carcinoma | 0.002714419 | 10 | 1 | BeFree |
Neoplasms, Radiation-Induced | 0.002638474 | 2 | 0 | BeFree_GAD |
Prostatic Neoplasms | 0.002638474 | 2 | 1 | BeFree_GAD |
Oxyphilic Adenoma | 0.002638474 | 2 | 1 | BeFree_GAD |
leukemia | 0.002442977 | 9 | 1 | BeFree |
Neuroblastoma | 0.002442977 | 9 | 1 | BeFree |
Follicular adenoma | 0.002442977 | 9 | 3 | BeFree |
Follicular neoplasm | 0.002442977 | 9 | 2 | BeFree |
Recurrent tumor | 0.002442977 | 9 | 1 | BeFree |
Central neuroblastoma | 0.002442977 | 9 | 1 | BeFree |
Tumors of Adrenal Cortex | 0.002367032 | 1 | 0 | GAD |
Alcoholic Intoxication, Chronic | 0.002367032 | 1 | 0 | GAD |
Articulation Disorders | 0.002367032 | 1 | 0 | GAD |
Carcinoma, Transitional Cell | 0.002367032 | 1 | 0 | GAD |
Neoplastic Cell Transformation | 0.002367032 | 1 | 0 | GAD |
Chromosome Aberrations | 0.002367032 | 1 | 0 | GAD |
Common Bile Duct Neoplasms | 0.002367032 | 1 | 0 | GAD |
Pathological Dilatation | 0.002367032 | 1 | 0 | GAD |
Dyslexia, Acquired | 0.002367032 | 1 | 0 | GAD |
Ectodermal Dysplasia | 0.002367032 | 1 | 0 | GAD |
Eosinophilia | 0.002367032 | 1 | 0 | GAD |
Esophageal Neoplasms | 0.002367032 | 1 | 0 | GAD |
Gingival Neoplasms | 0.002367032 | 1 | 0 | GAD |
Congenital Heart Defects | 0.002367032 | 1 | 0 | GAD |
Hyperplasia | 0.002367032 | 1 | 0 | GAD |
Immunologic Deficiency Syndromes | 0.002367032 | 1 | 0 | GAD |
Language Disorders | 0.002367032 | 1 | 0 | GAD |
Maxillary Neoplasms | 0.002367032 | 1 | 0 | GAD |
Mouth Neoplasms | 0.002367032 | 1 | 0 | GAD |
Nasopharyngeal Neoplasms | 0.002367032 | 1 | 0 | GAD |
Neoplasms, Germ Cell and Embryonal | 0.002367032 | 1 | 0 | GAD |
Testicular Neoplasms | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Tongue Neoplasms | 0.002367032 | 1 | 0 | GAD |
malignant neoplasm of frontal lobe | 0.002367032 | 1 | 1 | GAD |
Hyperpigmentation | 0.002367032 | 1 | 0 | GAD |
Cystadenocarcinoma, Mucinous | 0.002367032 | 1 | 0 | GAD |
Nerve Sheath Tumors | 0.002367032 | 1 | 0 | GAD |
Craniofacial Abnormalities | 0.002367032 | 1 | 0 | GAD |
Papillomavirus Infections | 0.002367032 | 1 | 0 | GAD |
Chromosomal Instability | 0.002367032 | 1 | 0 | GAD |
Necrotic changes (finding) | 0.002367032 | 1 | 0 | GAD |
Mucinous Adenocarcinoma | 0.002171535 | 8 | 1 | BeFree |
Pleomorphic Xanthoastrocytoma | 0.002171535 | 8 | 1 | BeFree |
Stomach Carcinoma | 0.002171535 | 8 | 0 | BeFree |
Malignant melanoma, metastatic | 0.002171535 | 8 | 2 | BeFree |
Adenocarcinoma of large intestine | 0.002171535 | 8 | 1 | BeFree |
Multiple Myeloma | 0.001900093 | 7 | 2 | BeFree |
Adenomatous Polyposis Coli | 0.001900093 | 7 | 1 | BeFree |
Undifferentiated carcinoma | 0.001900093 | 7 | 1 | BeFree |
Superficial spreading malignant melanoma of skin | 0.001900093 | 7 | 1 | BeFree |
Secondary malignant neoplasm of liver | 0.001900093 | 7 | 0 | BeFree |
Anaplasia | 0.001628651 | 6 | 1 | BeFree |
Lymphoma | 0.001628651 | 6 | 1 | BeFree |
Thyroiditis | 0.001628651 | 6 | 1 | BeFree |
Thyroid Gland Follicular Adenoma | 0.001628651 | 6 | 3 | BeFree |
Dysplastic Nevus | 0.001628651 | 6 | 1 | BeFree |
Medullary carcinoma of thyroid | 0.001628651 | 6 | 0 | BeFree |
Progressive Neoplastic Disease | 0.001628651 | 6 | 1 | BeFree |
Papillary microcarcinoma | 0.001628651 | 6 | 2 | BeFree |
Stage IV Skin Melanoma | 0.001628651 | 6 | 2 | BeFree |
Sessile Serrated Adenoma/Polyp | 0.001628651 | 6 | 1 | BeFree |
Progressive cGVHD | 0.001628651 | 6 | 1 | BeFree |
Malignant neoplasm of endometrium | 0.001357209 | 5 | 1 | BeFree |
Influenza | 0.001357209 | 5 | 1 | BeFree |
keratoacanthoma | 0.001357209 | 5 | 1 | BeFree |
B-Cell Lymphomas | 0.001357209 | 5 | 5 | BeFree |
Central Nervous System Neoplasms | 0.001357209 | 5 | 1 | BeFree |
Secondary malignant neoplasm of lung | 0.001357209 | 5 | 2 | BeFree |
Anaplastic carcinoma | 0.001357209 | 5 | 1 | BeFree |
Sarcoma, Clear Cell | 0.001357209 | 5 | 0 | BeFree |
Cholangiocarcinoma | 0.001357209 | 5 | 0 | BeFree |
Nevi and Melanomas | 0.001357209 | 5 | 1 | BeFree |
Squamous cell carcinoma of skin | 0.001357209 | 5 | 0 | BeFree |
Congenital melanocytic nevus | 0.001357209 | 5 | 1 | BeFree |
Limb-girdle muscular dystrophy type 2A | 0.001357209 | 5 | 0 | BeFree |
Uterine Corpus Cancer | 0.001357209 | 5 | 1 | BeFree |
Serrated polyp | 0.001357209 | 5 | 1 | BeFree |
Low grade serous carcinoma | 0.001357209 | 5 | 0 | BeFree |
Adenocarcinoma of prostate | 0.001085767 | 4 | 0 | BeFree |
Goiter | 0.001085767 | 4 | 0 | BeFree |
Chronic Lymphocytic Leukemia | 0.001085767 | 4 | 1 | BeFree |
Benign Neoplasm | 0.001085767 | 4 | 1 | BeFree |
Germ cell tumor | 0.001085767 | 4 | 0 | BeFree |
Carcinoma, Endometrioid | 0.001085767 | 4 | 1 | BeFree |
childhood brain tumor | 0.001085767 | 4 | 1 | BeFree |
Diffuse Astrocytoma | 0.001085767 | 4 | 1 | BeFree |
Multiple polyps | 0.001085767 | 4 | 1 | BeFree |
Serous cystadenoma, borderline malignancy | 0.001085767 | 4 | 1 | BeFree |
Acral Lentiginous Malignant Melanoma | 0.001085767 | 4 | 1 | BeFree |
Malignant melanoma of conjunctiva | 0.001085767 | 4 | 1 | BeFree |
Malignant neoplasm of pancreas | 0.001085767 | 4 | 0 | BeFree |
Splenic Marginal Zone B-Cell Lymphoma | 0.001085767 | 4 | 2 | BeFree |
Malignant neoplasm of prostate | 0.001085767 | 4 | 0 | BeFree |
Prostate carcinoma | 0.001085767 | 4 | 0 | BeFree |
Sentinel node (disorder) | 0.001085767 | 4 | 1 | BeFree |
Lymphocytic infiltration | 0.001085767 | 4 | 1 | BeFree |
Metanephric adenoma | 0.001085767 | 4 | 1 | BeFree |
Dysembryoplastic neuroepithelial tumor | 0.001085767 | 4 | 1 | BeFree |
Adenoma of large intestine | 0.001085767 | 4 | 0 | BeFree |
Primary Lesion | 0.001085767 | 4 | 1 | BeFree |
Xenograft Model | 0.001085767 | 4 | 1 | BeFree |
Rectal Tumors | 0.001085767 | 4 | 0 | BeFree |
Liver carcinoma | 0.001085767 | 4 | 0 | BeFree |
Endometriosis | 0.000814326 | 3 | 0 | BeFree |
Exanthema | 0.000814326 | 3 | 0 | BeFree |
Keratosis | 0.000814326 | 3 | 1 | BeFree |
Leukemia, Myelocytic, Acute | 0.000814326 | 3 | 0 | BeFree |
Nodule | 0.000814326 | 3 | 1 | BeFree |
oligodendroglioma | 0.000814326 | 3 | 0 | BeFree |
Adenoma, Villous | 0.000814326 | 3 | 0 | BeFree |
Pancreatic carcinoma | 0.000814326 | 3 | 0 | BeFree |
stage III melanoma | 0.000814326 | 3 | 0 | BeFree |
Tubular adenoma | 0.000814326 | 3 | 1 | BeFree |
Nodular melanoma | 0.000814326 | 3 | 0 | BeFree |
Anaplastic Oligodendroglioma | 0.000814326 | 3 | 1 | BeFree |
Adenocarcinoma of colon | 0.000814326 | 3 | 1 | BeFree |
Multiple malignancy | 0.000814326 | 3 | 0 | BeFree |
Hematologic Neoplasms | 0.000814326 | 3 | 0 | BeFree |
Tumor Initiation | 0.000814326 | 3 | 1 | BeFree |
Well Differentiated Oligodendroglioma | 0.000814326 | 3 | 0 | BeFree |
Malignant Peripheral Nerve Sheath Tumor | 0.000814326 | 3 | 1 | BeFree |
Intraepithelial Neoplasia | 0.000814326 | 3 | 0 | BeFree |
Polyp of large intestine | 0.000814326 | 3 | 0 | BeFree |
Squamous cell carcinoma of the head and neck | 0.000814326 | 3 | 0 | BeFree |
Mucinous Neoplasm | 0.000814326 | 3 | 0 | BeFree |
Invasive Skin Melanoma | 0.000814326 | 3 | 2 | BeFree |
Non-Neoplastic Disorder | 0.000814326 | 3 | 1 | BeFree |
IMMUNE SUPPRESSION | 0.000814326 | 3 | 1 | BeFree |
Lentigo maligna melanoma | 0.000814326 | 3 | 2 | BeFree |
Experimental Organism Basal Cell Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Anthrax disease | 0.000542884 | 2 | 1 | BeFree |
Arthralgia | 0.000542884 | 2 | 0 | BeFree |
Rheumatoid Arthritis | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of breast | 0.000542884 | 2 | 0 | BeFree |
Renal Cell Carcinoma | 0.000542884 | 2 | 1 | BeFree |
Chordoma | 0.000542884 | 2 | 0 | BeFree |
Congenital chromosomal disease | 0.000542884 | 2 | 1 | BeFree |
Ulcerative Colitis | 0.000542884 | 2 | 0 | BeFree |
Hypothyroidism | 0.000542884 | 2 | 1 | BeFree |
Infratentorial Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Lymphoproliferative Disorders | 0.000542884 | 2 | 1 | BeFree |
Neck Neoplasms | 0.000542884 | 2 | 0 | BeFree |
Panniculitis | 0.000542884 | 2 | 1 | BeFree |
Pituitary Adenoma | 0.000542884 | 2 | 0 | BeFree |
Retinoblastoma | 0.000542884 | 2 | 0 | BeFree |
Seizures | 0.000542884 | 2 | 1 | BeFree |
Dermatologic disorders | 0.000542884 | 2 | 0 | BeFree |
Secondary malignant neoplasm of skin | 0.000542884 | 2 | 0 | BeFree |
Lobular panniculitis | 0.000542884 | 2 | 0 | BeFree |
Stage III Colon Cancer | 0.000542884 | 2 | 1 | BeFree |
Malignant neoplasm of colon stage IV | 0.000542884 | 2 | 1 | BeFree |
Metastatic papillary thyroid carcinoma | 0.000542884 | 2 | 1 | BeFree |
Squamous cell carcinoma of esophagus | 0.000542884 | 2 | 0 | BeFree |
refractory hairy cell leukemia | 0.000542884 | 2 | 0 | BeFree |
Ovarian Teratoma | 0.000542884 | 2 | 0 | BeFree |
high-grade childhood cerebral astrocytoma | 0.000542884 | 2 | 1 | BeFree |
Tubulovillous adenoma | 0.000542884 | 2 | 0 | BeFree |
Struma ovarii, malignant | 0.000542884 | 2 | 1 | BeFree |
Giant Cell Glioblastoma | 0.000542884 | 2 | 1 | BeFree |
Intrahepatic Cholangiocarcinoma | 0.000542884 | 2 | 1 | BeFree |
Multiple nevi | 0.000542884 | 2 | 0 | BeFree |
Poorly differentiated carcinoma | 0.000542884 | 2 | 0 | BeFree |
Biliary Tract Cancer | 0.000542884 | 2 | 1 | BeFree |
Perineurioma | 0.000542884 | 2 | 1 | BeFree |
Hyperkeratosis | 0.000542884 | 2 | 0 | BeFree |
Autoimmune thyroiditis | 0.000542884 | 2 | 1 | BeFree |
Colorectal Traditional Serrated Adenoma | 0.000542884 | 2 | 0 | BeFree |
Hereditary Malignant Neoplasm | 0.000542884 | 2 | 0 | BeFree |
Ovarian Serous Adenocarcinoma | 0.000542884 | 2 | 0 | BeFree |
Pancreatic Ductal Adenocarcinoma | 0.000542884 | 2 | 1 | BeFree |
Primary Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Desmoplastic | 0.000542884 | 2 | 1 | BeFree |
Hereditary Melanoma | 0.000542884 | 2 | 1 | BeFree |
Adenocarcinoma, Endometrioid | 0.000542884 | 2 | 1 | BeFree |
Glioblastoma Multiforme | 0.000542884 | 2 | 1 | BeFree |
Low grade glioma | 0.000542884 | 2 | 0 | BeFree |
Stage III Colon Cancer AJCC v7 | 0.000542884 | 2 | 1 | BeFree |
Colorectal Serrated Adenocarcinoma | 0.000542884 | 2 | 1 | BeFree |
Serrated adenocarcinoma | 0.000542884 | 2 | 1 | BeFree |
Congenital Abnormality | 0.000271442 | 1 | 0 | BeFree |
Acromegaly | 0.000271442 | 1 | 0 | BeFree |
Carcinoid Tumor | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of skin | 0.000271442 | 1 | 0 | BeFree |
Cerebellar Ataxia | 0.000271442 | 1 | 0 | BeFree |
Cerebellar Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
Cystadenoma | 0.000271442 | 1 | 0 | BeFree |
Cystadenoma, Mucinous | 0.000271442 | 1 | 0 | BeFree |
Dermoid Cyst | 0.000271442 | 1 | 0 | BeFree |
Diarrhea | 0.000271442 | 1 | 0 | BeFree |
DiGeorge Syndrome | 0.000271442 | 1 | 0 | BeFree |
Epilepsy | 0.000271442 | 1 | 0 | BeFree |
Epilepsies, Partial | 0.000271442 | 1 | 0 | BeFree |
Fibrosarcoma | 0.000271442 | 1 | 1 | BeFree |
Flatulence | 0.000271442 | 1 | 0 | BeFree |
Giant Cell Tumors | 0.000271442 | 1 | 1 | BeFree |
Hepatolenticular Degeneration | 0.000271442 | 1 | 1 | BeFree |
HIV Infections | 0.000271442 | 1 | 1 | BeFree |
Actinic keratosis | 0.000271442 | 1 | 0 | BeFree |
Myeloid Leukemia, Chronic | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Myelomonocytic, Chronic | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Plasma Cell | 0.000271442 | 1 | 0 | BeFree |
Prolymphocytic Leukemia | 0.000271442 | 1 | 1 | BeFree |
Leukemoid Reaction | 0.000271442 | 1 | 1 | BeFree |
Lymphoma, Follicular | 0.000271442 | 1 | 1 | BeFree |
Medulloblastoma | 0.000271442 | 1 | 0 | BeFree |
Meningioma | 0.000271442 | 1 | 0 | BeFree |
Microphthalmos | 0.000271442 | 1 | 0 | BeFree |
Neoplastic Syndromes, Hereditary | 0.000271442 | 1 | 0 | BeFree |
Nervous System Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Neurilemmoma | 0.000271442 | 1 | 0 | BeFree |
Odontogenic Tumors | 0.000271442 | 1 | 1 | BeFree |
Pain | 0.000271442 | 1 | 0 | BeFree |
Pineal Gland Neoplasm | 0.000271442 | 1 | 1 | BeFree |
Pituitary Diseases | 0.000271442 | 1 | 1 | BeFree |
Plasmacytoma | 0.000271442 | 1 | 1 | BeFree |
Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
Seminoma | 0.000271442 | 1 | 0 | BeFree |
Skin lesion | 0.000271442 | 1 | 0 | BeFree |
Struma Ovarii | 0.000271442 | 1 | 0 | BeFree |
Tuberous Sclerosis | 0.000271442 | 1 | 1 | BeFree |
Xeroderma Pigmentosum | 0.000271442 | 1 | 0 | BeFree |
Diffuse Large B-Cell Lymphoma | 0.000271442 | 1 | 5 | BeFree |
Granular cell tumor | 0.000271442 | 1 | 1 | BeFree |
Synovial Cyst | 0.000271442 | 1 | 0 | BeFree |
Hutchinson's Melanotic Freckle | 0.000271442 | 1 | 0 | BeFree |
Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of rectum | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of mouth | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of anus | 0.000271442 | 1 | 0 | BeFree |
Uterine Cancer | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of brain | 0.000271442 | 1 | 0 | BeFree |
Iron deficiency anemia | 0.000271442 | 1 | 1 | BeFree |
Neurofibromatoses | 0.000271442 | 1 | 1 | BeFree |
Subependymal Giant Cell Astrocytoma | 0.000271442 | 1 | 1 | BeFree |
Embryonal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Adenomatous Polyps | 0.000271442 | 1 | 1 | BeFree |
Mucoepidermoid Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Signet Ring Cell | 0.000271442 | 1 | 1 | BeFree |
Melanoma, Amelanotic | 0.000271442 | 1 | 0 | BeFree |
Nevus, Blue | 0.000271442 | 1 | 0 | BeFree |
Shprintzen syndrome | 0.000271442 | 1 | 0 | BeFree |
Mastocytosis, Systemic | 0.000271442 | 1 | 2 | BeFree |
Dermatitis acneiform | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of penis | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Lewis Lung | 0.000271442 | 1 | 0 | BeFree |
Compound nevus of skin | 0.000271442 | 1 | 0 | BeFree |
Rhabdoid meningioma | 0.000271442 | 1 | 1 | BeFree |
Multiple tumors | 0.000271442 | 1 | 1 | BeFree |
Perianal fistula | 0.000271442 | 1 | 0 | BeFree |
Isovaleryl-CoA dehydrogenase deficiency | 0.000271442 | 1 | 1 | BeFree |
Malignant Childhood Neoplasm | 0.000271442 | 1 | 0 | BeFree |
adult glioblastoma | 0.000271442 | 1 | 1 | BeFree |
Anal carcinoma | 0.000271442 | 1 | 0 | BeFree |
Gallbladder adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Acinar cell carcinoma of pancreas | 0.000271442 | 1 | 0 | BeFree |
Cervical Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Oligodendroglioma, Childhood | 0.000271442 | 1 | 0 | BeFree |
Juvenile Pilocytic Astrocytoma | 0.000271442 | 1 | 1 | BeFree |
Cervix carcinoma | 0.000271442 | 1 | 0 | BeFree |
Adenomatous goiter | 0.000271442 | 1 | 1 | BeFree |
Inflammatory Myofibroblastic Tumor | 0.000271442 | 1 | 1 | BeFree |
Ameloblastic fibroma | 0.000271442 | 1 | 1 | BeFree |
Anaplastic astrocytoma | 0.000271442 | 1 | 0 | BeFree |
Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse | 0.000271442 | 1 | 1 | BeFree |
Histiocytic sarcoma | 0.000271442 | 1 | 1 | BeFree |
Iodine deficiency syndrome | 0.000271442 | 1 | 0 | BeFree |
Human papilloma virus infection | 0.000271442 | 1 | 0 | BeFree |
Adenoma of lung | 0.000271442 | 1 | 1 | BeFree |
Syringocystadenoma | 0.000271442 | 1 | 0 | BeFree |
Stage 0 Skin Melanoma | 0.000271442 | 1 | 1 | BeFree |
Malignant melanoma of iris | 0.000271442 | 1 | 1 | BeFree |
Malignant melanoma of choroid | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of anal margin | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of tongue | 0.000271442 | 1 | 0 | BeFree |
Atypical Endometrial Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Pilocytic astrocytoma of cerebellum | 0.000271442 | 1 | 0 | BeFree |
Hairy cell leukemia variant | 0.000271442 | 1 | 1 | BeFree |
Juvenile Myelomonocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
Trichoepithelioma | 0.000271442 | 1 | 0 | BeFree |
Syringocystadenoma Papilliferum | 0.000271442 | 1 | 0 | BeFree |
Papillary craniopharyngioma | 0.000271442 | 1 | 0 | BeFree |
Desmoplastic infantile astrocytoma | 0.000271442 | 1 | 1 | BeFree |
Leukemia, Prolymphocytic, B-Cell | 0.000271442 | 1 | 0 | BeFree |
Benign neurologic neoplasms | 0.000271442 | 1 | 0 | BeFree |
Stage IV Colorectal Cancer | 0.000271442 | 1 | 0 | BeFree |
Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Terminal illness | 0.000271442 | 1 | 1 | BeFree |
Skin carcinoma | 0.000271442 | 1 | 0 | BeFree |
Dissecting aneurysm of the thoracic aorta | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of kidney | 0.000271442 | 1 | 0 | BeFree |
Central nervous system lesion | 0.000271442 | 1 | 0 | BeFree |
Benign thyroid nodule | 0.000271442 | 1 | 1 | BeFree |
Lafora Disease | 0.000271442 | 1 | 0 | BeFree |
endocrine carcinoma | 0.000271442 | 1 | 1 | BeFree |
premalignant lesion | 0.000271442 | 1 | 1 | BeFree |
Colorectal cancer recurrent | 0.000271442 | 1 | 0 | BeFree |
Rhabdoid Tumor of the Kidney | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung, stage IV | 0.000271442 | 1 | 0 | BeFree |
Advanced cancer | 0.000271442 | 1 | 0 | BeFree |
cancer recurrence | 0.000271442 | 1 | 0 | BeFree |
precancerous lesions | 0.000271442 | 1 | 0 | BeFree |
High weight | 0.000271442 | 1 | 0 | BeFree |
Hurthle Cell Tumor | 0.000271442 | 1 | 1 | BeFree |
Chromosome 17 trisomy | 0.000271442 | 1 | 0 | BeFree |
Stage IV Esophageal Squamous Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Nevus cell nevus | 0.000271442 | 1 | 1 | BeFree |
Myxoid cyst | 0.000271442 | 1 | 0 | BeFree |
Dendritic Cell Sarcoma, Follicular | 0.000271442 | 1 | 0 | BeFree |
Morphologically altered structure | 0.000271442 | 1 | 0 | BeFree |
Neoplasm of temporal lobe | 0.000271442 | 1 | 0 | BeFree |
Poorly Differentiated Thyroid Carcinoma | 0.000271442 | 1 | 1 | BeFree |
Diffuse melanocytosis | 0.000271442 | 1 | 1 | BeFree |
Desmoplastic spindle and epithelioid cell melanocytic nevus of skin | 0.000271442 | 1 | 0 | BeFree |
Pancreatic intraepithelial neoplasia | 0.000271442 | 1 | 2 | BeFree |
Myopericytoma | 0.000271442 | 1 | 1 | BeFree |
Eruptive melanocytic nevi | 0.000271442 | 1 | 0 | BeFree |
Papillary Renal Cell Carcinoma | 0.000271442 | 1 | 1 | BeFree |
Astrocytoma, low grade | 0.000271442 | 1 | 0 | BeFree |
Non-toxic nodular goiter | 0.000271442 | 1 | 1 | BeFree |
Torre-Muir syndrome | 0.000271442 | 1 | 1 | BeFree |
Adenocarcinoma of the gastroesophageal junction | 0.000271442 | 1 | 1 | BeFree |
Colorectal Villous Adenoma | 0.000271442 | 1 | 0 | BeFree |
Desmoplastic melanoma | 0.000271442 | 1 | 0 | BeFree |
High Grade Intraepithelial Neoplasia | 0.000271442 | 1 | 0 | BeFree |
Histiocytic and Dendritic Cell Neoplasm | 0.000271442 | 1 | 1 | BeFree |
Invasive Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Leptomeningeal Melanoma | 0.000271442 | 1 | 0 | BeFree |
Metastatic Malignant Peripheral Nerve Sheath Tumor | 0.000271442 | 1 | 1 | BeFree |
Optic Nerve Astrocytoma | 0.000271442 | 1 | 0 | BeFree |
Spindle Cell Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Thyroid Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Epithelioma | 0.000271442 | 1 | 0 | BeFree |
Mature Teratoma | 0.000271442 | 1 | 0 | BeFree |
Oncocytic Neoplasm | 0.000271442 | 1 | 1 | BeFree |
Renal carcinoma | 0.000271442 | 1 | 1 | BeFree |
Tumor of the Pineal Region | 0.000271442 | 1 | 1 | BeFree |
Anal squamous cell carcinoma | 0.000271442 | 1 | 0 | BeFree |
Mammary Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Colorectal Signet Ring Cell Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Radiation Recall Dermatitis | 0.000271442 | 1 | 0 | BeFree |
SKIN/HAIR/EYE PIGMENTATION, VARIATION IN, 2 (disorder) | 0.000271442 | 1 | 0 | BeFree |
NEPHROTIC SYNDROME, TYPE 3 | 0.000271442 | 1 | 0 | BeFree |
Plasma Cell Neoplasm | 0.000271442 | 1 | 1 | BeFree |
Urachal adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Stage III Skin Melanoma | 0.000271442 | 1 | 0 | BeFree |
Intramucosal Adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Stage IV Colorectal Cancer AJCC v7 | 0.000271442 | 1 | 0 | BeFree |
Papillary Meningioma | 0.000271442 | 1 | 1 | BeFree |
TUMOR PREDISPOSITION SYNDROME | 0.000271442 | 1 | 0 | BeFree |
Micropapillary carcinoma | 0.000271442 | 1 | 0 | BeFree |
Familial Nonmedullary Thyroid Cancer | 0.000271442 | 1 | 1 | BeFree |
Ovarian low malignant potential tumour | 0.000271442 | 1 | 0 | BeFree |
Classical Glioblastoma | 0.000271442 | 1 | 1 | BeFree |
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