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This gene encodes one of seven subunits of the human Arp2/3 protein complex. The Arp2/3 protein complex has been implicated in the control of actin polymerization in cells and has been conserved through evolution. The exact role of the protein encoded by this gene, the p16 subunit, has yet to be determined. Alternatively spliced transcript variants encoding different isoforms have been observed for this gene. [provided by RefSeq, Jul 2012]
[中文简述(自动翻译):]  该基因编码的7个亚基的人类的Arp2 / 3蛋白质复合物中的一个。所述的Arp2 / 3蛋白质复合物已经牵涉于肌动蛋白聚合在细胞中的控制,并已通过进化保守的。由该基因,所述p16蛋白亚基编码的蛋白质的确切作用,还有待确定。编码不同同种型的可变剪接转录物变体已经观察到这种基因。 [由RefSeq的,2012年7月提供]
ARPC5基因(以及对应的蛋白质)的细胞分布位置:
ARPC5基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Rhabdomyosarcoma | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
invasive cancer | 0.000271442 | 1 | 0 | BeFree |
Squamous cell carcinoma of the head and neck | 0.000271442 | 1 | 0 | BeFree |
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