ARF6(ADP-ribosylation factor 6) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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14q21.3
基因染色体位置图

This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的人类ARF基因家族,它是在RAS超家族的部分的构件。 ARF的基因编码刺激霍乱毒素的ADP-核糖基转移酶活性,并在囊泡运输和作为该基因的产物被定位于质膜的磷脂酶D的活化剂发挥作用小鸟嘌呤核苷酸结合蛋白,并调节囊泡运输,重塑膜脂的,和信令,导致肌动蛋白重塑通路。该基因的假基因位于[由RefSeq的,2008年7月提供] 7号染色体

ARF6基因的碱基序列:[NCBI]
ARF6基因的碱基突变:           显示全部snp
rs15382       rs1064615       rs3100898       rs3100908       rs3100909       rs3126180       rs3179189       rs8012313       rs11552918       rs61732572       rs61734985       rs61755563       rs61755575       rs61758874       rs72680046       rs73273802       rs73275404       rs74711338       rs75400672       rs75618848       rs75672063       rs76302504       rs77308076       rs111484414       rs112017635       rs112211624       rs112755109       rs112858996       rs113960725       rs114395201       rs114513764       rs114990188       rs115892318       rs117146976       rs117302051       rs117373659       rs117650746      
rs118174578       rs138151813       rs138800769       rs138807394       rs138905564       rs140339761       rs140399482       rs140492524       rs140506930       rs140819900       rs141035771       rs141900404       rs141992302       rs143656735       rs144888092       rs145045252       rs145059127       rs145570777       rs146326091       rs147968439       rs148543337       rs149310850       rs150130970       rs150646777       rs150659935       rs181163514       rs181594154       rs182367262       rs182736285       rs183371046       rs183471540       rs183494601       rs184420714       rs184860348       rs185946318       rs186566342       rs187777195       rs187956517       rs188785257       rs189279224       rs190349237       rs190716215       rs190843251       rs191326708       rs192253781       rs192393000       rs192855008       rs192856974       rs199598489       rs200695445       rs201401465       rs201725640       rs368010518       rs369105384       rs369138632       rs371217905       rs371547662       rs372474363       rs372949566       rs373061714       rs373412874       rs375262270       rs375413551       rs375473057       rs376018460       rs527464763       rs527539648       rs527738749       rs528118484       rs528132510       rs528941926       rs529007760       rs529326920       rs530276908       rs530379898       rs530462938       rs530504148       rs531582622       rs531794083       rs532731427       rs532852555       rs533135797       rs533776196       rs533819997       rs533841476       rs533916032       rs534300134       rs534880102       rs534953772       rs535089265       rs535482315       rs535698691       rs535745763       rs536111990       rs536319235       rs537248754       rs537310276       rs537902204       rs537919229       rs537960015       rs538512094       rs539051494       rs539101567       rs539420370       rs539504801       rs540226077       rs541365147       rs542052987       rs542177000       rs542418640       rs542464282       rs543014201       rs543325218       rs543595827       rs543810832       rs544191647       rs544618605       rs544729252       rs546431753       rs546502089       rs547169128       rs547230601       rs547553457       rs547566936       rs548311221       rs548383619       rs548696241       rs548797330       rs548834969       rs549308060       rs549769124       rs551024365       rs551262981       rs551336313       rs552109866       rs552712480       rs552741821       rs552803515       rs553231953       rs553513509       rs553878753       rs554347117       rs554905833       rs555436280       rs555505994       rs556067033       rs556070544       rs556216835       rs556561734       rs557017124       rs557231179       rs557474672       rs557878288       rs557954266       rs558678193       rs559015031       rs559451823       rs560637464       rs560814967       rs562015741       rs562805900       rs562847169       rs563068263       rs563305846       rs563503027       rs563611120       rs564112546       rs564217389       rs564356070       rs564509428       rs565297462       rs566425091       rs566439290       rs566980328       rs567044312       rs567460586       rs567789986       rs569062453       rs569187172       rs569578819       rs569642342       rs569887439       rs570343509       rs570493819       rs570557132       rs570569222       rs572228711       rs572391602       rs572623999       rs572734042       rs573370245       rs574002524       rs574175855       rs574521612       rs575053502       rs575259203       rs576310474       rs576615115       rs577569307       rs577733616       rs577846423       rs577964352       rs578011899       rs745628393       rs745683323       rs747694604       rs748042646       rs748114612       rs748170831       rs749008836       rs749233938       rs749309161       rs750730156       rs751003183       rs752233598       rs752466709       rs752673573       rs753315410       rs753915241       rs754412742       rs754637279       rs754692332       rs755570395       rs755693781       rs756048522       rs757158549       rs757165904       rs757772096       rs757936468       rs758254684       rs758835566       rs760817062       rs761695417       rs761927063       rs762265071       rs762830845       rs763451475       rs763604943       rs764556170       rs765182402       rs765630104       rs765793301       rs766708308       rs767302736       rs768345984       rs769571499       rs769861336       rs772166799       rs774416954       rs774810229       rs776640440       rs776747690       rs778869182       rs779804891       rs780782180       rs781260800       rs796563362      

ARF6基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CACTGTGGGTTTCAACGTG
60
ATCCCATACGTTGAACTTGAC
59
GCACCGCATTATCAATGAC
58
CTTGTTGGCGAAGATGAGG
59
TGCACCGCATTATCAATGAC
59
TTGTTGGCGAAGATGAGGA
59
      尚未收录相关数据

ARF6基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ARF6基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0001726
P62330(UniProtKB)
IDA
GO:0001889
P62330(UniProtKB)
IEA
GO:0003924
P62330(UniProtKB)
TAS
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005515
P62330(UniProtKB)
IPI
GO:0005525
P62330(UniProtKB)
TAS
GO:0005768
P62330(UniProtKB)
TAS
GO:0005768
P62330(UniProtKB)
IDA
GO:0005769
P62330(UniProtKB)
IEA
GO:0005794
P62330(UniProtKB)
IEA
GO:0005886
P62330(UniProtKB)
IDA
GO:0005886
P62330(UniProtKB)
IDA
GO:0005886
P62330(UniProtKB)
IDA
GO:0005925
P62330(UniProtKB)
IDA
GO:0005938
P62330(UniProtKB)
IDA
GO:0006928
P62330(UniProtKB)
TAS
GO:0007049
P62330(UniProtKB)
IEA
GO:0007155
P62330(UniProtKB)
TAS
GO:0007264
P62330(UniProtKB)
IEA
GO:0015031
P62330(UniProtKB)
IEA
GO:0016020
P62330(UniProtKB)
IDA
GO:0016192
P62330(UniProtKB)
TAS
GO:0030139
P62330(UniProtKB)
IDA
GO:0030496
P62330(UniProtKB)
IEA
GO:0030838
P62330(UniProtKB)
IMP
GO:0030866
P62330(UniProtKB)
IMP
GO:0031527
P62330(UniProtKB)
IDA
GO:0031529
P62330(UniProtKB)
IDA
GO:0031996
P62330(UniProtKB)
IPI
GO:0032154
P62330(UniProtKB)
IEA
GO:0033028
P62330(UniProtKB)
IEA
GO:0034394
P62330(UniProtKB)
ISS
GO:0035020
P62330(UniProtKB)
IDA
GO:0036010
P62330(UniProtKB)
IMP
GO:0043209
P62330(UniProtKB)
IEA
GO:0047485
P62330(UniProtKB)
IEA
GO:0048261
P62330(UniProtKB)
TAS
GO:0051301
P62330(UniProtKB)
IEA
GO:0051489
P62330(UniProtKB)
IDA
GO:0055038
P62330(UniProtKB)
IDA
GO:0060998
P62330(UniProtKB)
ISS
GO:0070062
P62330(UniProtKB)
IDA
GO:0070062
P62330(UniProtKB)
IDA
GO:0070062
P62330(UniProtKB)
IDA
GO:0090004
P62330(UniProtKB)
ISS
GO:0090162
P62330(UniProtKB)
IEA
GO:0097284
P62330(UniProtKB)
IEA
GO:2000171
P62330(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ARF6基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Mammary Neoplasms 0.0054487 2 0 LHGDN
Glioma 0.003267234 2 0 BeFree_LHGDN
melanoma 0.002995792 2 0 BeFree_LHGDN
Neoplasm Metastasis 0.001900093 7 0 BeFree
Malignant neoplasm of breast 0.001357209 5 0 BeFree
Breast Carcinoma 0.001357209 5 0 BeFree
HIV Infections 0.000814326 3 0 BeFree
Invasive breast carcinoma 0.000814326 3 0 BeFree
Cyst 0.000271442 1 0 BeFree
Ischemia 0.000271442 1 0 BeFree
Liver neoplasms 0.000271442 1 0 BeFree
Pregnancy Complications 0.000271442 1 0 BeFree
Seizures 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lung 0.000271442 1 0 BeFree
Niemann-Pick Disease, Type C 0.000271442 1 0 BeFree
Vesicular Stomatitis 0.000271442 1 0 BeFree
Epilepsy, Myoclonic, Infantile 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree
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