ARF1(ADP-ribosylation factor 1)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

基因染色体位置

基因染色体位置

1q42.13
基因染色体位置图

基因简述

基因简述

ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products, including 6 ARF proteins and 11 ARF-like proteins, constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1, ARF2 and ARF3), class II (ARF4 and ARF5) and class III (ARF6), and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  ADP-核糖基化因子1（ARF1）是人ARF基因家族的一个成员。家族成员编码刺激霍乱毒素的ADP-核糖基转移酶活性，发挥作为磷脂酶D的活化剂的基因产物在囊泡运输作用小鸟嘌呤核苷酸结合蛋白，其中包括6 ARF蛋白和11 ARF样蛋白，构成了家庭RAS超家族。东盟地区论坛蛋白质被归类为I类（ARF1，ARF2和ARF3），II级（ARF4和ARF5）和III（ARF6）类，每一类都有一个共同的基因组织成员。所述ARF1蛋白定位于高尔基体和具有内高尔基体运输中心作用。已发现了该基因编码的蛋白质相同的多个可变剪接转录变异体。 [由RefSeq的，2008年7月提供]

OMIM数据库中对ARF1基因的介绍     Wikipedia数据库中对ARF1基因的介绍

基因序列

基因序列

ARF1基因的碱基序列：[NCBI]

基因突变

基因突变

ARF1基因的碱基突变：           显示全部snp
rs6920       rs13338       rs14892       rs708125       rs708126       rs822725       rs822726       rs822727       rs822728       rs822732       rs822733       rs822734       rs822741       rs1048503       rs1048504       rs1188975       rs1771466       rs1803041       rs1803141       rs1803143       rs1832733       rs2070960       rs3210485       rs3738681       rs3738682       rs3754355       rs3754356       rs3754357       rs3754358       rs3754359       rs3768327       rs3768329       rs3768330       rs3768331       rs3820624       rs6694537       rs7531973      
rs11420776       rs11541554       rs11541556       rs11541557       rs11541558       rs11541562       rs11576568       rs11582265       rs11582704       rs12029076       rs12128981       rs41270179       rs41304008       rs55686465       rs55954688       rs56003736       rs60245137       rs60434323       rs61737797       rs72756221       rs72756224       rs73092942       rs73092944       rs73092948       rs73092953       rs73092954       rs73092957       rs73092959       rs74140914       rs74140915       rs74140916       rs74140918       rs74140919       rs74140920       rs74140923       rs74140924       rs74140925       rs74140953       rs74140954       rs74140955       rs74140956       rs74140957       rs74140959       rs74140960       rs74140961       rs76298113       rs76865338       rs76904171       rs77084929       rs77571032       rs77944238       rs78044256       rs78445387       rs78593148       rs78698634       rs79077765       rs79172508       rs111791585       rs111913120       rs112104801       rs112401439       rs112615324       rs112958994       rs112977005       rs113063082       rs113470196       rs113597226       rs113612894       rs113688673       rs113698704       rs114719657       rs114741819       rs114893377       rs115113469       rs115359398       rs115388234       rs115403594       rs115647813       rs116167748       rs116255732       rs116271163       rs116310529       rs116438423       rs117024647       rs117028801       rs117527601       rs117557365       rs117741092       rs117832221       rs117972114       rs118063156       rs138003565       rs138021613       rs138465651       rs138522441       rs138872498       rs138970398       rs139432130       rs139664315       rs139734880       rs139782920       rs139866128       rs140445676       rs140605599       rs140627450       rs141769989       rs141922842       rs141962428       rs141980219       rs142007288       rs142418933       rs142552660       rs143219597       rs143310687       rs143463838       rs143545613       rs143714855       rs143956326       rs143994218       rs144083555       rs144244496       rs144283575       rs144506745       rs145061958       rs145096108       rs145339426       rs145664954       rs145716642       rs146400368       rs146725028       rs146827674       rs147118089       rs147354087       rs147361238       rs147516885       rs147571768       rs147852605       rs148104986       rs148364166       rs148416492       rs148909619       rs149161835       rs149483340       rs149597044       rs149650053       rs149870497       rs150361570       rs150507258       rs150674534       rs150861841       rs151241631       rs180823844       rs180924220       rs181137048       rs181583151       rs181613537       rs181720624       rs181959195       rs181993401       rs182129906       rs182360923       rs182737956       rs182794534       rs182964692       rs183378628       rs183383265       rs183490175       rs183631631       rs183737434       rs183937457       rs184012798       rs184154397       rs184526515       rs184582928       rs184971411       rs184995384       rs185058639       rs185608851       rs185732595       rs185747528       rs185819366       rs186173462       rs186274135       rs186306550       rs186421978       rs186630111       rs186642862       rs187026506       rs187257280       rs187290486       rs187703170       rs187898639       rs187966915       rs188267598       rs188299143       rs188504506       rs188514091       rs188744771       rs189047528       rs189174790       rs189197150       rs189314731       rs189416140       rs190017241       rs190070574       rs190223947       rs190655227       rs190713298       rs190720228       rs190956243       rs190969663       rs190988870       rs191226104       rs191312262       rs191358228       rs191471860       rs191518376       rs191540999       rs191562404       rs192793671       rs193051254       rs199599231       rs199638762       rs200443433       rs200482095       rs200601102       rs200690064       rs200897192       rs201067408       rs201163189       rs201369768       rs201797905       rs201854692       rs201883341       rs202149186       rs202182320       rs202220531       rs367780730       rs368007905       rs368033068       rs368278171       rs368437375       rs368524793       rs369031105       rs369190394       rs369406797       rs369646198       rs369759823       rs370463658       rs370671237       rs370867199       rs371394465       rs371465731       rs371617800       rs371749303       rs371761353       rs371767087       rs372012030       rs373235197       rs373278091       rs373532921       rs373715936       rs373902191       rs374058258       rs374548874       rs375115515       rs375387304       rs375556877       rs375875865       rs375926182       rs376465077       rs377173283       rs377716619       rs397812351       rs527486345       rs527616203       rs528436726       rs528902399       rs528949880       rs528966005       rs529450250       rs529590332       rs529619815       rs529769042       rs530016939       rs530422615       rs530513739       rs531003299       rs531279299       rs531340365       rs531464824       rs531464979       rs531471427       rs531523370       rs531945582       rs532003675       rs532064037       rs532346144       rs532484617       rs532549997       rs532852550       rs532960010       rs533072312       rs533136493       rs533198655       rs533286861       rs533302236       rs533350846       rs533410937       rs533473581       rs533762266       rs533863230       rs533984626       rs534318618       rs534372729       rs534668423       rs534963135       rs535151775       rs535211590       rs535223325       rs535286760       rs535462991       rs535639833       rs535717120       rs536228723       rs536308691       rs536352994       rs536709138       rs536772767       rs537047757       rs537109123       rs537167396       rs537648948       rs537771970       rs537836021       rs537897365       rs538004456       rs538105971       rs538336689       rs538626102       rs538722003       rs539504677       rs539655251       rs539707758       rs540023978       rs540224948       rs540285627       rs540332311       rs540407067       rs540468715       rs540746510       rs540851978       rs540911586       rs541766022       rs541965227       rs542103568       rs542166732       rs542190911       rs542243644       rs542253298       rs542305017       rs542775659       rs542838794       rs543056287       rs543254202       rs544116588       rs544205122       rs544263833       rs544582756       rs544657513       rs544720596       rs544917656       rs544962869       rs545256038       rs545424727       rs545634637       rs545733239       rs545733342       rs546135210       rs546263867       rs546601294       rs546662786       rs546662893       rs546725771       rs546788784       rs546805625       rs546982162       rs547445170       rs547506683       rs547738774       rs548143947       rs548587025       rs548672072       rs548735959       rs548800807       rs548816746       rs548867962       rs548879731       rs549421254       rs549568902       rs549946165       rs550062351       rs550219266       rs550638037       rs550748750       rs550800168       rs551132235       rs551265703       rs551594260       rs551735653       rs552633189       rs552986915       rs553175261       rs553236724       rs553292564       rs553722674       rs554035684       rs554365538       rs554494125       rs554648509       rs555105464       rs555173592       rs555238680       rs555244231       rs555300200       rs555307225       rs555310854       rs555513672       rs555569455       rs555696095       rs555853250       rs556008685       rs556384738       rs556559961       rs556722826       rs557097702       rs557224358       rs557636077       rs557700020       rs557759351       rs557821076       rs558162954       rs559288298       rs559511463       rs559682667       rs559744868       rs559783427       rs559809416       rs560041250       rs560178180       rs560272783       rs560609119       rs560882764       rs561080486       rs561162493       rs561224888       rs561622315       rs561966838       rs562027309       rs562030249       rs562091520       rs562150561       rs562260823       rs562299506       rs562500420       rs562533215       rs562882116       rs563032375       rs563064036       rs563306023       rs563501825       rs563593871       rs563629772       rs564128136       rs564355410       rs564360770       rs564430100       rs564599279       rs564696841       rs564696874       rs565168649       rs565434714       rs565511779       rs565554616       rs565745827       rs566091714       rs566228177       rs566288974       rs566673918       rs567212242       rs567478294       rs567491415       rs567551884       rs567589483       rs567665392       rs567693214       rs567725435       rs567919051       rs567980068       rs568202758       rs568466904       rs568578695       rs568655334       rs568716304       rs568854378       rs568918854       rs568988721       rs569038087       rs569052059       rs569525222       rs570147191       rs570207184       rs570272319       rs570385484       rs570544858       rs570730438       rs570794893       rs570857367       rs570915025       rs571131009       rs571194077       rs571255053       rs571299202       rs571623240       rs571721074       rs571784332       rs572208899       rs573066110       rs573070940       rs573088663       rs573214182       rs573251300       rs573368435       rs573706903       rs574182209       rs574581844       rs574645236       rs575071589       rs575120238       rs575493853       rs575640121       rs575642024       rs575705716       rs575996771       rs576441823       rs576639514       rs576719211       rs576840789       rs576856190       rs576912401       rs577182995       rs577185000       rs577247156       rs577626893       rs577969843       rs578074868       rs745371226       rs745638410       rs746041095       rs746117851       rs746211512       rs746250685       rs746936604       rs747063787       rs747344148       rs747469592       rs747640292       rs748152912       rs748951714       rs749353761       rs749994289       rs750093483       rs750719848       rs750890801       rs751395152       rs751420953       rs751547585       rs751656654       rs751679760       rs752069371       rs752138967       rs752583036       rs752867627       rs752915360       rs753396348       rs754126054       rs754134486       rs754248760       rs754506796       rs754859607       rs755237018       rs755663535       rs756404286       rs757653610       rs758439811       rs758944972       rs759638959       rs760365227       rs760445481       rs760840584       rs761151232       rs761910680       rs762183426       rs762388073       rs762419898       rs762769241       rs763048237       rs763615109       rs764037349       rs764142633       rs764690724       rs765536091       rs765917983       rs765973759       rs766057583       rs766906376       rs766959640       rs767176898       rs767885108       rs768348405       rs768803103       rs768860382       rs769527124       rs769901189       rs769925136       rs771140686       rs771191633       rs771901253       rs772867236       rs773772662       rs774332380       rs774460920       rs775027460       rs775417374       rs776199101       rs776618422       rs776938681       rs777310017       rs777847166       rs778178441       rs778231514       rs779130765       rs779199839       rs780442475       rs780499813       rs781034886       rs781347783       rs781667395      

基因表达

基因表达

ARF1基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank

转录因子

转录因子

      尚未收录相关数据

基因本体信息

ARF1基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ARF1基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000139
P84077(UniProtKB)
TAS
GO:0000287
P84077(UniProtKB)
IEA
GO:0002090
P84077(UniProtKB)
ISS
GO:0003924
P84077(UniProtKB)
TAS
GO:0005057
P84077(UniProtKB)
TAS
GO:0005515
P84077(UniProtKB)
IPI
GO:0005515
P84077(UniProtKB)
IPI
GO:0005515
P84077(UniProtKB)
IPI
GO:0005515
P84077(UniProtKB)
IPI
GO:0005525
P84077(UniProtKB)
IEA
GO:0005770
P84077(UniProtKB)
IEA
GO:0005778
P84077(UniProtKB)
IEA
GO:0005802
P84077(UniProtKB)
IEA
GO:0005829
P84077(UniProtKB)
TAS
GO:0005829
P84077(UniProtKB)
TAS
GO:0005829
P84077(UniProtKB)
TAS
GO:0005829
P84077(UniProtKB)
TAS
GO:0005829
P84077(UniProtKB)
TAS
GO:0005886
P84077(UniProtKB)
TAS
GO:0005925
P84077(UniProtKB)
IDA
GO:0006661
P84077(UniProtKB)
TAS
GO:0006878
P84077(UniProtKB)
IMP
GO:0006892
P84077(UniProtKB)
TAS
GO:0007015
P84077(UniProtKB)
IEA
GO:0007264
P84077(UniProtKB)
IEA
GO:0014069
P84077(UniProtKB)
IEA
GO:0015031
P84077(UniProtKB)
IEA
GO:0019003
P84077(UniProtKB)
IEA
GO:0019886
P84077(UniProtKB)
TAS
GO:0030017
P84077(UniProtKB)
IEA
GO:0030137
P84077(UniProtKB)
IEA
GO:0031252
P84077(UniProtKB)
IDA
GO:0034315
P84077(UniProtKB)
ISS
GO:0034379
P84077(UniProtKB)
IEA
GO:0043005
P84077(UniProtKB)
IEA
GO:0043085
P84077(UniProtKB)
IEA
GO:0044822
P84077(UniProtKB)
IDA
GO:0045211
P84077(UniProtKB)
IEA
GO:0045807
P84077(UniProtKB)
IEA
GO:0045956
P84077(UniProtKB)
IEA
GO:0048471
P84077(UniProtKB)
IEA
GO:0050690
P84077(UniProtKB)
TAS
GO:0050714
P84077(UniProtKB)
IEA
GO:0055108
P84077(UniProtKB)
IEA
GO:0060292
P84077(UniProtKB)
ISS
GO:0060999
P84077(UniProtKB)
IEA
GO:0070062
P84077(UniProtKB)
IDA
GO:0070062
P84077(UniProtKB)
IDA
GO:0070062
P84077(UniProtKB)
IDA
GO:0070142
P84077(UniProtKB)
IEA
GO:0097061
P84077(UniProtKB)
ISS
GO:0097212
P84077(UniProtKB)
IEA
GO:1902307
P84077(UniProtKB)
IEA
GO:1902824
P84077(UniProtKB)
IEA
GO:1902953
P84077(UniProtKB)
IEA
GO:1903725
P84077(UniProtKB)
IEA
GO:1990583
P84077(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控ARF1基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Mammary Neoplasms 0.00272435 1 0 LHGDN
Alzheimer's Disease 0.002367032 1 0 GAD
Occupational Diseases 0.002367032 1 0 GAD
Malignant neoplasm of breast 0.000542884 2 0 BeFree
Breast Carcinoma 0.000542884 2 0 BeFree
Invasive breast carcinoma 0.000542884 2 0 BeFree
Hepatitis C 0.000271442 1 0 BeFree
HIV Infections 0.000271442 1 0 BeFree
Malignant neoplasm of stomach 0.000271442 1 0 BeFree
Neoplasm Metastasis 0.000271442 1 0 BeFree
Pregnancy Complications 0.000271442 1 0 BeFree
Secondary malignant neoplasm of lymph node 0.000271442 1 0 BeFree
Stomach Carcinoma 0.000271442 1 0 BeFree
Triple Negative Breast Neoplasms 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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