ARAF(A-Raf proto-oncogene, serine/threonine kinase)

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

Xp11.3-p11.23
基因染色体位置图

基因简述

基因简述

This proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family, and maybe involved in cell growth and development. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2012]

[中文简述(自动翻译):]  此原癌基因属于丝氨酸/苏氨酸蛋白激酶家族的RAF亚科，并可能参与了细胞生长和发展。另外剪接转录变体编码不同亚型也发现了这种基因。[由RefSeq的，2012年1月提供]

OMIM数据库中对ARAF基因的介绍     Wikipedia数据库中对ARAF基因的介绍

基因序列

基因序列

ARAF基因的碱基序列：[NCBI]

基因突变

基因突变

ARAF基因的碱基突变：           显示全部snp
rs781331960       rs781365647       rs781486338       rs781542979       rs781552146       rs781686176       rs781240605       rs781322933       rs780867304       rs780922452       rs780996530       rs780865351       rs780659300       rs780670855       rs780711176       rs780749477       rs780758789       rs780796257       rs780124992       rs780127695       rs780206875       rs780348121       rs780392324       rs780392848       rs780564206       rs779859676       rs780035176       rs780115698       rs780121164       rs779625869       rs779648831       rs779656098       rs779665380       rs779799263       rs779283787       rs779522126       rs779536112      
rs777769604       rs777809178       rs778002431       rs778119620       rs778205718       rs778488722       rs778514331       rs778667261       rs778786139       rs778980583       rs779045731       rs777385122       rs777457066       rs777520349       rs777673041       rs776827612       rs776910843       rs776912006       rs777024024       rs777037087       rs777093232       rs777175520       rs777175765       rs776073253       rs776408725       rs776439001       rs776490790       rs776540006       rs776560513       rs776577117       rs775904188       rs775921012       rs775949802       rs775966352       rs775984740       rs775988261       rs775997759       rs774931935       rs775128697       rs775214073       rs775219418       rs775441061       rs774526444       rs774536124       rs774656593       rs774684341       rs774700067       rs774850025       rs774853161       rs774136414       rs774178390       rs774324085       rs774386947       rs773749825       rs773785392       rs773815973       rs773875137       rs774003798       rs773388926       rs773486607       rs773650920       rs773696719       rs773740883       rs773303308       rs773318953       rs772870138       rs772981429       rs773119164       rs773124118       rs773133805       rs771900273       rs772013716       rs772162483       rs772172490       rs772352972       rs772382146       rs772504191       rs772745800       rs772779121       rs771822290       rs771826915       rs771600984       rs771625964       rs771259913       rs771326103       rs771396364       rs771482270       rs770499440       rs770823568       rs770926246       rs770936172       rs771127790       rs771246106       rs770405383       rs770445607       rs770447410       rs770472571       rs770073846       rs770223449       rs770315817       rs769320920       rs769391257       rs769569122       rs769591973       rs769771152       rs769785079       rs768995750       rs769020473       rs769230579       rs769318807       rs768545081       rs768707858       rs768961381       rs768240348       rs768265504       rs768276363       rs768334456       rs768457112       rs767445776       rs767450736       rs767525192       rs767742694       rs767772118       rs767351676       rs767410181       rs766967905       rs767252492       rs767264051       rs767276942       rs767292603       rs766393500       rs766479029       rs766556609       rs766573991       rs766585429       rs766682123       rs766876031       rs766950453       rs766226234       rs766305105       rs766317364       rs765367783       rs765492001       rs765633363       rs765643325       rs765906700       rs765916064       rs765976834       rs766074870       rs765207392       rs765069634       rs765113993       rs765133394       rs764907490       rs765027205       rs764666706       rs764756092       rs764809054       rs764853511       rs764520676       rs764585247       rs764627700       rs764637755       rs764281834       rs764348546       rs764471960       rs764098004       rs764252445       rs764255925       rs763548006       rs763604914       rs763811160       rs763947223       rs763988785       rs762248696       rs762249776       rs762622187       rs762815942       rs762844944       rs763056037       rs763218688       rs763339134       rs763351013       rs761717103       rs761893348       rs761923485       rs761931410       rs761939456       rs761605587       rs761686069       rs761480447       rs761521516       rs761203440       rs761271837       rs761339166       rs761115487       rs761117537       rs761174890       rs760979113       rs760613124       rs760779442       rs760805269       rs760815147       rs760847926       rs760190272       rs760280370       rs760360817       rs760446501       rs760490837       rs760524207       rs759912060       rs759985490       rs760150595       rs759617144       rs759638440       rs759778132       rs759839307       rs759903646       rs759594960       rs759484232       rs759554784       rs759472903       rs759466793       rs759472062       rs758729232       rs758823877       rs759062565       rs759100402       rs759275896       rs758499112       rs758512147       rs758558184       rs758605550       rs758399040       rs758447492       rs757678586       rs758004948       rs758018031       rs758229241       rs758233964       rs757311093       rs757426955       rs757062015       rs757208902       rs756864414       rs756992932       rs757049859       rs756771141       rs756786368       rs756794740       rs756684682       rs756687085       rs756741810       rs756181998       rs756419246       rs756483901       rs756511455       rs756671375       rs755898303       rs755914916       rs755941801       rs755969290       rs755693043       rs755892791       rs755586743       rs755638812       rs755675686       rs755528563       rs754922399       rs755147398       rs755229896       rs755308260       rs755324203       rs755329086       rs754549302       rs754716027       rs754787460       rs754794814       rs754803899       rs754420498       rs754547557       rs754104664       rs754144370       rs754272256       rs754332483       rs754412271       rs753847991       rs753945757       rs754040192       rs753607536       rs753329721       rs753515210       rs753550613       rs753171944       rs753185948       rs753276084       rs752936098       rs752937927       rs752973673       rs751985012       rs752231168       rs752282820       rs752678087       rs752699379       rs752848207       rs751749230       rs751815158       rs751893264       rs750855708       rs750893495       rs751114324       rs751184651       rs751559150       rs751634782       rs751707690       rs751709389       rs750598176       rs750635130       rs750651936       rs750670489       rs750765947       rs750158439       rs750251352       rs750411643       rs750559969       rs750570398       rs749630923       rs749678414       rs749734176       rs749784842       rs749829012       rs750008187       rs749304573       rs749347703       rs749435690       rs749564014       rs748685491       rs748716871       rs748829115       rs748893688       rs748995528       rs749120411       rs749134130       rs749214520       rs748492203       rs748580515       rs748627763       rs748240627       rs748299249       rs747850611       rs747863271       rs747904029       rs747994720       rs748003720       rs748127267       rs747694131       rs747707114       rs747761715       rs747470700       rs747676688       rs747252047       rs747425746       rs747148984       rs747224772       rs746987091       rs747076883       rs746855375       rs746574967       rs746605740       rs746691883       rs746021042       rs746126878       rs746296307       rs746478186       rs745710674       rs745726706       rs745997765       rs745998042       rs745434460       rs745515941       rs745536344       rs745346659       rs576251770       rs745341869       rs745346439       rs571234670       rs562812579       rs550399272       rs544848648       rs538541233       rs377336364       rs377675069       rs530561450       rs373428883       rs375468186       rs375687398       rs376043774       rs376069946       rs376147525       rs376276271       rs376771155       rs376805803       rs376873254       rs372151497       rs372462744       rs372758216       rs372763934       rs373018619       rs373156329       rs371017890       rs371119291       rs371146151       rs371173578       rs371247311       rs371444512       rs371819543       rs371865941       rs372033812       rs369700331       rs369811610       rs370026622       rs370203307       rs370327383       rs370446747       rs370587460       rs368024349       rs368550075       rs368665293       rs369107922       rs369477994       rs201871676       rs202121223       rs367636050       rs367956581       rs201394917       rs201555958       rs201857678       rs200660377       rs200882727       rs201204685       rs200237581       rs200466529       rs200542934       rs193224605       rs199513093       rs199527940       rs199723158       rs199870928       rs200151563       rs192546485       rs193144729       rs191688019       rs192006891       rs190214159       rs190764446       rs191296408       rs189666845       rs189699904       rs189855204       rs188247834       rs188382893       rs188499184       rs188561806       rs187706116       rs187909030       rs187225161       rs186861544       rs186803716       rs186800352       rs186479348       rs185676793       rs185381177       rs185177644       rs184888793       rs185025075       rs184385427       rs184671455       rs184861193       rs183389918       rs183656189       rs183789909       rs183374829       rs182791384       rs182662916       rs182258374       rs182065228       rs181095516       rs181459331       rs181794483       rs151113368       rs151191170       rs151030523       rs149635355       rs150631376       rs148802221       rs148814895       rs149184484       rs148450866       rs147086204       rs147548336       rs148135033       rs146665387       rs146772116       rs146376823       rs146356268       rs143523393       rs143528736       rs143620653       rs144376609       rs145056294       rs145939962       rs142950815       rs143159753       rs143306300       rs143311445       rs143463830       rs142304168       rs142914348       rs141965190       rs142277089       rs141631560       rs139914837       rs140123739       rs140761699       rs140920401       rs141126913       rs138292173       rs139093707       rs139161665       rs139796547       rs113508989       rs113512925       rs111857170       rs112114956       rs112568375       rs112667575       rs112763002       rs112933282       rs111600057       rs111825402       rs73496208       rs111385806       rs73206125       rs73494399       rs66838530       rs67832160       rs67867352       rs62636601       rs62636602       rs62636603       rs62636604       rs61665240       rs62622372       rs62636600       rs61103761       rs56202823       rs56322617       rs56014229       rs55852926       rs12556182       rs34574198       rs55846150       rs11551157       rs11797215       rs5953058       rs5906432       rs2855131       rs2855136       rs2858769       rs2854426       rs2854422       rs2854420       rs2854419       rs2854418       rs2854412       rs2283736       rs2187804       rs1050175       rs1130962       rs2071776       rs2071777       rs1050133       rs1050151       rs10066      

基因表达

基因表达

ARAF基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CATCAAGGGACGAAAGACG
59
CAAGGACCTCGACAATGAG
58
CGTGACCAGATTATCTTTATGGTG
60
ACTTGAGGCAGTCAGACAG
59
CAGTGAAGACTCGATGGAG
57
ATACGGATCACCTCAGCTG
59
ATCAAGGGACGAAAGACGG
60
AAGGACCTCGACAATGAGC
60
AGTGAAGACTCGATGGAGC
59
CATACGGATCACCTCAGCT
59
AGTGAAGACTCGATGGAGC
59
ATACGGATCACCTCAGCTG
59
GTGACCAGATTATCTTTATGGTGG
59
ACTTGAGGCAGTCAGACAG
59
ATCAAGGGACGAAAGACGG
60
TCAAGGACCTCGACAATGAG
60
CCGTGACCAGATTATCTTTATGG
59
ACTTGAGGCAGTCAGACAG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

ARAF基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ARAF基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0000165
P10398(UniProtKB)
TAS
GO:0004672
P10398(UniProtKB)
TAS
GO:0004674
P10398(UniProtKB)
IDA
GO:0005057
P10398(UniProtKB)
IEA
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005515
P10398(UniProtKB)
IPI
GO:0005524
P10398(UniProtKB)
IEA
GO:0005575
P10398(UniProtKB)
ND
GO:0005829
P10398(UniProtKB)
TAS
GO:0005829
P10398(UniProtKB)
TAS
GO:0005829
P10398(UniProtKB)
TAS
GO:0005829
P10398(UniProtKB)
TAS
GO:0005829
P10398(UniProtKB)
TAS
GO:0005829
P10398(UniProtKB)
TAS
GO:0006464
P10398(UniProtKB)
TAS
GO:0032006
P10398(UniProtKB)
IMP
GO:0032434
P10398(UniProtKB)
IMP
GO:0033138
P10398(UniProtKB)
IDA
GO:0043066
P10398(UniProtKB)
IDA
GO:0046872
P10398(UniProtKB)
IEA
GO:0000165
Q96II5(UniProtKB)
IEA
GO:0000186
Q96II5(UniProtKB)
IEA
GO:0004709
Q96II5(UniProtKB)
IEA
GO:0005515
Q96II5(UniProtKB)
IPI
GO:0005515
Q96II5(UniProtKB)
IPI
GO:0005524
Q96II5(UniProtKB)
IEA
GO:0005739
Q96II5(UniProtKB)
IEA
GO:0005829
Q96II5(UniProtKB)
IEA
GO:0046872
Q96II5(UniProtKB)
IEA

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控ARAF基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Mammary Neoplasms 0.12 1 0 CTD_human
Adenocarcinoma 0.002995792 1 0 BeFree_LHGDN
melanoma 0.001085767 4 0 BeFree
Glioblastoma 0.000542884 2 0 BeFree
Histiocytosis, Langerhans-Cell 0.000542884 2 0 BeFree
Autistic Disorder 0.000271442 1 0 BeFree
Adenocarcinoma of lung (disorder) 0.000271442 1 0 BeFree
Cone dystrophy 0.000271442 1 0 BeFree
Testicular Germ Cell Tumor 0.000271442 1 0 BeFree
Liver carcinoma 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

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