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The androgen receptor gene is more than 90 kb long and codes for a protein that has 3 major functional domains: the N-terminal domain, DNA-binding domain, and androgen-binding domain. The protein functions as a steroid-hormone activated transcription factor. Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. This gene contains 2 polymorphic trinucleotide repeat segments that encode polyglutamine and polyglycine tracts in the N-terminal transactivation domain of its protein. Expansion of the polyglutamine tract causes spinal bulbar muscular atrophy (Kennedy disease). Mutations in this gene are also associated with complete androgen insensitivity (CAIS). Two alternatively spliced variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
[中文简述(自动翻译):]  雄激素受体基因是超过90 kb的长码为具有3个主要的功能域的蛋白质的N-末端结构域,DNA结合域,和雄激素结合结构域。该蛋白质用作类固醇激素激活的转录因子。在结合的激素配体,受体从辅助蛋白解离,易位到细胞核中,二聚化,然后刺激的雄激素应答基因的转录。该基因包含编码多聚和聚甘氨酸束在其蛋白的N端反式激活结构域2多态型三核苷酸重复段。多聚谷氨酰胺道的膨胀导致脊髓延髓肌萎缩症(肯尼迪病)。在这个基因的突变也与完整的雄激素不敏感(CAIS)有关。两个编码不同同种型选择性剪接的变体已有描述。 [由RefSeq的,2008年7月提供]
AR基因(以及对应的蛋白质)的细胞分布位置:
AR基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Androgen-Insensitivity Syndrome | 0.541871118 | 185 | 10 | BeFree_CLINVAR_CTD_human_GAD_LHGDN_MGD_UNIPROT |
Reifenstein Syndrome | 0.375472187 | 79 | 18 | BeFree_CLINVAR_ORPHANET_UNIPROT |
Prostatic Neoplasms | 0.320998992 | 226 | 2 | BeFree_CTD_human_GAD_LHGDN_RGD |
Bulbo-Spinal Atrophy, X-Linked | 0.280097452 | 140 | 1 | BeFree_CLINVAR_GAD_ORPHANET |
Malignant neoplasm of prostate | 0.28 | 1372 | 12 | BeFree_CLINVAR_GAD |
Hypospadias 1, X-Linked | 0.24 | 0 | 2 | CLINVAR_CTD_human |
Hypertensive disease | 0.202638474 | 5 | 0 | BeFree_CTD_human_GAD_RGD |
Male infertility | 0.187371256 | 55 | 1 | BeFree_CTD_human_GAD_LHGDN |
Mammary Neoplasms | 0.165493578 | 38 | 0 | BeFree_CTD_human_GAD_LHGDN |
Atrophy, Muscular, Spinobulbar | 0.149858606 | 110 | 0 | BeFree_ORPHANET |
Liver carcinoma | 0.136968811 | 26 | 0 | BeFree_CTD_human_GAD_LHGDN |
Alopecia | 0.134202192 | 7 | 0 | CTD_human_GAD |
Insulin Resistance | 0.127101096 | 4 | 0 | CTD_human_GAD |
Autistic Disorder | 0.12554839 | 4 | 0 | BeFree_CTD_human_GAD |
Female infertility | 0.124734064 | 3 | 0 | CTD_human_GAD |
Prostatic Intraepithelial Neoplasias | 0.12408156 | 7 | 0 | BeFree_CTD_human_LHGDN |
Neoplasm Recurrence, Local | 0.122367032 | 2 | 0 | CTD_human_GAD |
Bulbospinal neuronopathy, X-linked recessive | 0.121900093 | 7 | 0 | BeFree_CTD_human |
leukemia | 0.120814326 | 3 | 0 | BeFree_CTD_human |
Bulbospinal Neuronopathy | 0.120814326 | 3 | 0 | BeFree_ORPHANET |
Astrocytoma | 0.12 | 1 | 0 | CTD_human |
Gestational Diabetes | 0.12 | 1 | 0 | CTD_human |
Breast Neoplasms, Male | 0.12 | 2 | 0 | CTD_human |
Malignant neoplasm of breast | 0.098610816 | 161 | 0 | BeFree_GAD |
Prostatic Hyperplasia | 0.095545589 | 8 | 0 | BeFree_GAD_LHGDN_RGD |
Osteoporosis | 0.089087065 | 8 | 0 | BeFree_GAD_LHGDN_RGD |
Diabetes Mellitus, Non-Insulin-Dependent | 0.08554839 | 4 | 0 | BeFree_GAD_MGD |
Obesity | 0.083995683 | 6 | 0 | BeFree_GAD_MGD |
Diabetes Mellitus, Experimental | 0.08 | 1 | 0 | RGD |
Prostate carcinoma | 0.08 | 1357 | 7 | BeFree |
Sarcopenia | 0.08 | 1 | 0 | RGD |
Testicular Feminization | 0.060184151 | 213 | 5 | BeFree_GAD |
Polycystic Ovary Syndrome | 0.041267891 | 27 | 1 | BeFree_GAD_LHGDN |
Breast Carcinoma | 0.039901955 | 147 | 0 | BeFree |
Oligospermia | 0.033485834 | 22 | 0 | BeFree_GAD |
Malignant neoplasm of ovary | 0.025450861 | 25 | 0 | BeFree_GAD |
Endometrial Neoplasms | 0.025099593 | 8 | 0 | GAD_LHGDN |
Hypospadias | 0.023341458 | 25 | 0 | BeFree_GAD_LHGDN |
Carcinogenesis | 0.022258234 | 82 | 0 | BeFree |
Cryptorchidism | 0.02099817 | 16 | 0 | BeFree_GAD_LHGDN |
Neoplasm Metastasis | 0.020020685 | 56 | 0 | BeFree_GAD_LHGDN |
androgen independent prostate cancer | 0.018110661 | 58 | 1 | BeFree_GAD |
Azoospermia | 0.015635346 | 19 | 0 | BeFree_GAD |
Fibroid Tumor | 0.013907006 | 7 | 0 | BeFree_GAD_LHGDN |
Virilism | 0.013148762 | 32 | 0 | BeFree_GAD |
Adenocarcinoma | 0.012344368 | 21 | 0 | BeFree_GAD_LHGDN |
Androgenetic Alopecia | 0.012334436 | 28 | 4 | BeFree_GAD |
Klinefelter Syndrome | 0.011996981 | 11 | 0 | BeFree_GAD_LHGDN |
Muscular Atrophy | 0.011973237 | 17 | 0 | BeFree_LHGDN |
ovarian neoplasm | 0.011711727 | 7 | 0 | BeFree_LHGDN |
Benign Prostatic Hyperplasia | 0.010510288 | 30 | 4 | BeFree_GAD |
Tumor Progression | 0.010314791 | 38 | 1 | BeFree |
Endometriosis | 0.010282454 | 4 | 0 | BeFree_GAD |
Testicular Neoplasms | 0.010282454 | 7 | 0 | BeFree_GAD |
Hormone refractory prostate cancer | 0.008957582 | 33 | 0 | BeFree |
Ovarian Failure, Premature | 0.008544182 | 4 | 0 | BeFree_GAD_LHGDN |
Acne Vulgaris | 0.00764398 | 4 | 0 | BeFree_GAD |
Alzheimer's Disease | 0.00764398 | 5 | 0 | BeFree_GAD |
Motor Neuron Disease | 0.007600372 | 28 | 0 | BeFree |
Metastatic Prostate Carcinoma | 0.007600372 | 28 | 0 | BeFree |
Ovarian Carcinoma | 0.007328931 | 27 | 0 | BeFree |
Chromosome Aberrations | 0.007101096 | 3 | 0 | GAD |
Animal Mammary Neoplasms | 0.007101096 | 3 | 0 | GAD |
Uterine Neoplasms | 0.007101096 | 3 | 0 | GAD |
Ovarian Diseases | 0.006981544 | 18 | 1 | BeFree_GAD |
Carcinoma of Male Breast | 0.006981544 | 17 | 2 | BeFree_GAD |
Rheumatoid Arthritis | 0.006905599 | 8 | 0 | BeFree_GAD |
Hyperandrogenism | 0.006634157 | 8 | 0 | BeFree_GAD |
Liver neoplasms | 0.006362715 | 8 | 0 | BeFree_GAD |
Neurodegenerative Disorders | 0.006243163 | 23 | 0 | BeFree |
Congenital adrenal hyperplasia | 0.00617715 | 5 | 1 | BeFree_GAD_LHGDN |
Esophageal Neoplasms | 0.005905708 | 4 | 0 | BeFree_GAD_LHGDN |
Endometrial Carcinoma | 0.005895776 | 13 | 0 | BeFree_GAD |
Metabolic Syndrome X | 0.005819831 | 4 | 0 | BeFree_GAD |
Bladder Neoplasm | 0.005634266 | 4 | 0 | BeFree_GAD_LHGDN |
Coronary Artery Disease | 0.005634266 | 3 | 0 | BeFree_GAD_LHGDN |
Malignant neoplasm of urinary bladder | 0.005624334 | 13 | 0 | BeFree_GAD |
Malignant neoplasm of esophagus | 0.00554839 | 4 | 0 | BeFree_GAD |
Penile hypospadias | 0.005428837 | 20 | 0 | BeFree |
Left Ventricular Hypertrophy | 0.005362824 | 1 | 0 | BeFree_GAD_LHGDN |
Alcoholic Intoxication, Chronic | 0.005276948 | 4 | 0 | BeFree_GAD |
Anoxia | 0.005091382 | 2 | 0 | GAD_LHGDN |
Hypertrophic Cardiomyopathy | 0.005091382 | 1 | 0 | GAD_LHGDN |
Head and Neck Neoplasms | 0.005091382 | 1 | 0 | GAD_LHGDN |
Hyperplasia | 0.005091382 | 2 | 0 | GAD_LHGDN |
Lymphoma, Non-Hodgkin | 0.005091382 | 2 | 0 | GAD_LHGDN |
Mammographic Density | 0.005005506 | 2 | 0 | BeFree_GAD |
Epithelial ovarian cancer | 0.004810009 | 10 | 0 | BeFree_GAD |
Diabetic Retinopathy | 0.004734064 | 2 | 0 | GAD |
Infertility | 0.004734064 | 2 | 0 | GAD |
Microsatellite Instability | 0.004734064 | 2 | 0 | GAD |
Mental Depression | 0.004538567 | 9 | 0 | BeFree_GAD |
Turner Syndrome | 0.004353001 | 6 | 0 | BeFree_LHGDN |
Gynecomastia | 0.004267125 | 8 | 1 | BeFree_GAD |
Hypogonadism | 0.004267125 | 8 | 0 | BeFree_GAD |
Substance Withdrawal Syndrome | 0.004267125 | 8 | 0 | BeFree_GAD |
Triple Negative Breast Neoplasms | 0.004071628 | 15 | 0 | BeFree |
Male Pseudohermaphroditism | 0.003800186 | 14 | 0 | BeFree |
Malignant neoplasm of male breast | 0.003800186 | 14 | 2 | BeFree |
Prostate cancer recurrent | 0.003528744 | 13 | 0 | BeFree |
Malignant tumor of colon | 0.003452799 | 4 | 0 | BeFree_GAD |
Mixed Salivary Gland Tumor | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Spinal Muscular Atrophy | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Thrombocytosis | 0.003267234 | 2 | 0 | BeFree_LHGDN |
Pulmonary Sclerosing Hemangioma | 0.003267234 | 2 | 0 | BeFree_LHGDN |
Carcinoma of bladder | 0.003257302 | 12 | 0 | BeFree |
Renal Cell Carcinoma | 0.003181358 | 3 | 0 | BeFree_GAD |
Machado-Joseph Disease | 0.003181358 | 4 | 0 | BeFree_GAD |
Schizophrenia | 0.003181358 | 4 | 0 | BeFree_GAD |
Ataxia, Spinocerebellar | 0.003181358 | 3 | 0 | BeFree_GAD |
Invasive Ductal Breast Carcinoma | 0.003181358 | 4 | 0 | BeFree_GAD |
Chordoma | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Stomach Neoplasms | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Adenocarcinoma of prostate | 0.002985861 | 11 | 0 | BeFree |
Atherosclerosis | 0.002909916 | 3 | 0 | BeFree_GAD |
Heart Diseases | 0.002909916 | 2 | 0 | BeFree_GAD |
Myocardial Infarction | 0.002909916 | 2 | 0 | BeFree_GAD |
Degenerative polyarthritis | 0.002909916 | 2 | 0 | BeFree_GAD |
Dyslipidemias | 0.002909916 | 2 | 0 | BeFree_GAD |
Major Depressive Disorder | 0.002909916 | 2 | 0 | BeFree_GAD |
Penis agenesis | 0.002909916 | 3 | 0 | BeFree_GAD |
Spontaneous abortion | 0.00272435 | 1 | 0 | LHGDN |
Long QT Syndrome | 0.00272435 | 1 | 0 | LHGDN |
Malignant neoplasm of endometrium | 0.002714419 | 10 | 0 | BeFree |
Uterine Corpus Cancer | 0.002714419 | 10 | 0 | BeFree |
Rectal Carcinoma | 0.002638474 | 2 | 0 | BeFree_GAD |
Cholelithiasis | 0.002638474 | 2 | 0 | BeFree_GAD |
Colonic Neoplasms | 0.002638474 | 2 | 0 | BeFree_GAD |
Hepatitis C | 0.002638474 | 2 | 0 | BeFree_GAD |
Seminoma | 0.002638474 | 2 | 0 | BeFree_GAD |
Fibroadenoma | 0.002638474 | 1 | 0 | BeFree_GAD |
Cancer of Head and Neck | 0.002638474 | 1 | 0 | BeFree_GAD |
Testicular Germ Cell Tumor | 0.002638474 | 2 | 0 | BeFree_GAD |
Hepatitis B | 0.002442977 | 9 | 0 | BeFree |
Neuromuscular Diseases | 0.002442977 | 9 | 0 | BeFree |
Testicular malignant germ cell tumor | 0.002442977 | 9 | 0 | BeFree |
Abortion, Habitual | 0.002367032 | 1 | 0 | GAD |
Angina Pectoris, Variant | 0.002367032 | 1 | 0 | GAD |
As If Personality | 0.002367032 | 1 | 0 | GAD |
Biliary Tract Neoplasm | 0.002367032 | 1 | 0 | GAD |
Brain Ischemia | 0.002367032 | 1 | 0 | GAD |
Colorectal Neoplasms | 0.002367032 | 1 | 0 | GAD |
Gonadal Dysgenesis, 46,XY | 0.002367032 | 1 | 0 | GAD |
Hirsutism | 0.002367032 | 1 | 0 | GAD |
Lung Neoplasms | 0.002367032 | 1 | 0 | GAD |
Lymphopenia | 0.002367032 | 1 | 0 | GAD |
Myotonic Dystrophy | 0.002367032 | 1 | 0 | GAD |
Neoplasms, Germ Cell and Embryonal | 0.002367032 | 1 | 0 | GAD |
Neoplasms, Hormone-Dependent | 0.002367032 | 1 | 0 | GAD |
Osteoporosis, Postmenopausal | 0.002367032 | 1 | 0 | GAD |
Pre-Eclampsia | 0.002367032 | 1 | 0 | GAD |
Prenatal Exposure Delayed Effects | 0.002367032 | 1 | 0 | GAD |
Sex Chromosome Aberrations | 0.002367032 | 1 | 0 | GAD |
Cerebrovascular accident | 0.002367032 | 1 | 0 | GAD |
Ureteral Neoplasms | 0.002367032 | 1 | 0 | GAD |
Severe Combined Immunodeficiency | 0.002367032 | 1 | 0 | GAD |
Migraine Disorders | 0.002367032 | 1 | 0 | GAD |
Memory impairment | 0.002367032 | 1 | 0 | GAD |
Substance-Related Disorders | 0.002367032 | 1 | 0 | GAD |
Large prostate | 0.002367032 | 1 | 0 | GAD |
body mass | 0.002367032 | 1 | 0 | GAD |
Pregnancy loss | 0.002367032 | 1 | 0 | GAD |
Myoclonic Epilepsies, Progressive | 0.002367032 | 1 | 0 | GAD |
Muscular Disorders, Atrophic | 0.002367032 | 1 | 0 | GAD |
Cholecystolithiasis | 0.002367032 | 1 | 0 | GAD |
Congenital absence of germinal epithelium of testes | 0.002367032 | 1 | 0 | GAD |
Phenotypic heterogeneity | 0.002367032 | 1 | 0 | GAD |
Memory Impairment Adverse Event | 0.002367032 | 1 | 0 | GAD |
Weight Loss Adverse Event | 0.002367032 | 1 | 0 | GAD |
Ovarian Hyperandrogenism | 0.002367032 | 1 | 0 | GAD |
Depressive disorder | 0.002171535 | 8 | 0 | BeFree |
Uterine Fibroids | 0.002171535 | 8 | 0 | BeFree |
Spastic syndrome | 0.002171535 | 8 | 0 | BeFree |
Hepatocarcinogenesis | 0.002171535 | 8 | 0 | BeFree |
Amyotrophic Lateral Sclerosis | 0.001900093 | 7 | 0 | BeFree |
Prostatic Diseases | 0.001900093 | 7 | 1 | BeFree |
Secondary malignant neoplasm of bone | 0.001900093 | 7 | 0 | BeFree |
Ambiguous Genitalia | 0.001900093 | 7 | 1 | BeFree |
Progressive Neoplastic Disease | 0.001900093 | 7 | 0 | BeFree |
Xenograft Model | 0.001900093 | 7 | 0 | BeFree |
46, XY Disorders of Sex Development | 0.001900093 | 7 | 0 | BeFree |
Progressive cGVHD | 0.001900093 | 7 | 0 | BeFree |
Carcinoma, Transitional Cell | 0.001628651 | 6 | 0 | BeFree |
Congenital chromosomal disease | 0.001628651 | 6 | 0 | BeFree |
Muscle Weakness | 0.001628651 | 6 | 0 | BeFree |
Recurrent tumor | 0.001628651 | 6 | 0 | BeFree |
Carcinoma of lung | 0.001628651 | 6 | 0 | BeFree |
Female Breast Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Colorectal Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Myeloid Leukemia, Chronic | 0.001357209 | 5 | 0 | BeFree |
Pituitary Diseases | 0.001357209 | 5 | 0 | BeFree |
Depressive Symptoms | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of testis | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of female breast | 0.001357209 | 5 | 0 | BeFree |
Malignant neoplasm of lung | 0.001357209 | 5 | 0 | BeFree |
Hypogonadotropic hypogonadism | 0.001357209 | 5 | 0 | BeFree |
stage, prostate cancer | 0.001357209 | 5 | 0 | BeFree |
46, XY female | 0.001357209 | 5 | 0 | BeFree |
Colon Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Cardiomyopathy, Familial Idiopathic | 0.001357209 | 5 | 0 | BeFree |
Urothelial Carcinoma | 0.001357209 | 5 | 0 | BeFree |
Congenital Abnormality | 0.001085767 | 4 | 0 | BeFree |
Adenoma | 0.001085767 | 4 | 0 | BeFree |
Coronary Arteriosclerosis | 0.001085767 | 4 | 0 | BeFree |
Mental Retardation | 0.001085767 | 4 | 0 | BeFree |
Nephroblastoma | 0.001085767 | 4 | 0 | BeFree |
nervous system disorder | 0.001085767 | 4 | 0 | BeFree |
Neuroblastoma | 0.001085767 | 4 | 0 | BeFree |
Paresis | 0.001085767 | 4 | 0 | BeFree |
Retinoblastoma | 0.001085767 | 4 | 0 | BeFree |
Disorders of Sex Development | 0.001085767 | 4 | 0 | BeFree |
Thrombocythemia, Essential | 0.001085767 | 4 | 0 | BeFree |
Esophageal carcinoma | 0.001085767 | 4 | 0 | BeFree |
Congenital malformation of genital organs | 0.001085767 | 4 | 1 | BeFree |
Primary physiologic amenorrhea | 0.001085767 | 4 | 0 | BeFree |
Alcohol withdrawal syndrome | 0.001085767 | 4 | 0 | BeFree |
Carcinoma, Small Cell | 0.001085767 | 4 | 0 | BeFree |
Klinefelter's syndrome - male with more than two X chromosomes | 0.001085767 | 4 | 0 | BeFree |
Hypospadias, penoscrotal | 0.001085767 | 4 | 0 | BeFree |
Secondary malignant neoplasm of lymph node | 0.001085767 | 4 | 0 | BeFree |
Central neuroblastoma | 0.001085767 | 4 | 0 | BeFree |
Spinocerebellar Ataxia Type 1 | 0.001085767 | 4 | 0 | BeFree |
Degenerative disorder | 0.001085767 | 4 | 0 | BeFree |
Non-Neoplastic Disorder | 0.001085767 | 4 | 0 | BeFree |
Aortic Valve Insufficiency | 0.000814326 | 3 | 0 | BeFree |
Noninfiltrating Intraductal Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Squamous cell carcinoma | 0.000814326 | 3 | 0 | BeFree |
Coronary heart disease | 0.000814326 | 3 | 0 | BeFree |
Diabetes | 0.000814326 | 3 | 0 | BeFree |
Diabetes Mellitus | 0.000814326 | 3 | 0 | BeFree |
Muscular fasciculation | 0.000814326 | 3 | 0 | BeFree |
Chronic granulomatous disease | 0.000814326 | 3 | 0 | BeFree |
Histiocytosis, Langerhans-Cell | 0.000814326 | 3 | 0 | BeFree |
Lymphoma | 0.000814326 | 3 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000814326 | 3 | 0 | BeFree |
Myopathy | 0.000814326 | 3 | 0 | BeFree |
Thyroid Neoplasm | 0.000814326 | 3 | 0 | BeFree |
Atrophy of testis | 0.000814326 | 3 | 0 | BeFree |
Germ cell tumor | 0.000814326 | 3 | 0 | BeFree |
Papillary thyroid carcinoma | 0.000814326 | 3 | 0 | BeFree |
Pseudovaginal Perineoscrotal Hypospadias | 0.000814326 | 3 | 0 | BeFree |
Familial Motor Neuron Disease | 0.000814326 | 3 | 0 | BeFree |
Motor Neuron Disease, Lower | 0.000814326 | 3 | 0 | BeFree |
Thyroid carcinoma | 0.000814326 | 3 | 0 | BeFree |
Stomach Carcinoma | 0.000814326 | 3 | 0 | BeFree |
21-hydroxylase deficiency | 0.000814326 | 3 | 0 | BeFree |
Apocrine Gland Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Prostate cancer, familial | 0.000814326 | 3 | 1 | BeFree |
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency | 0.000814326 | 3 | 0 | BeFree |
5-Alpha Reductase Deficiency | 0.000814326 | 3 | 0 | BeFree |
Refractory anemias | 0.000542884 | 2 | 0 | BeFree |
Arteriosclerosis | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of thyroid | 0.000542884 | 2 | 0 | BeFree |
Phyllodes Tumor | 0.000542884 | 2 | 0 | BeFree |
Cyst | 0.000542884 | 2 | 0 | BeFree |
Muscular Dystrophy, Duchenne | 0.000542884 | 2 | 0 | BeFree |
Epilepsy | 0.000542884 | 2 | 0 | BeFree |
Glioblastoma | 0.000542884 | 2 | 0 | BeFree |
Hematological Disease | 0.000542884 | 2 | 0 | BeFree |
Herpes Simplex Infections | 0.000542884 | 2 | 0 | BeFree |
HIV Infections | 0.000542884 | 2 | 0 | BeFree |
Huntington Disease | 0.000542884 | 2 | 0 | BeFree |
Hypopituitarism | 0.000542884 | 2 | 0 | BeFree |
Acute Promyelocytic Leukemia | 0.000542884 | 2 | 0 | BeFree |
Lupus Vulgaris | 0.000542884 | 2 | 0 | BeFree |
Lupus Erythematosus, Discoid | 0.000542884 | 2 | 0 | BeFree |
Lupus Erythematosus, Systemic | 0.000542884 | 2 | 0 | BeFree |
melanoma | 0.000542884 | 2 | 0 | BeFree |
Multiple Endocrine Neoplasia Type 2a | 0.000542884 | 2 | 0 | BeFree |
Meningioma | 0.000542884 | 2 | 0 | BeFree |
Premature Menopause | 0.000542884 | 2 | 0 | BeFree |
Myeloproliferative disease | 0.000542884 | 2 | 0 | BeFree |
Adenomatous Polyposis Coli | 0.000542884 | 2 | 0 | BeFree |
Kaposi Sarcoma | 0.000542884 | 2 | 0 | BeFree |
Scrub Typhus | 0.000542884 | 2 | 0 | BeFree |
Sertoli Cell Tumor | 0.000542884 | 2 | 0 | BeFree |
Dermatologic disorders | 0.000542884 | 2 | 0 | BeFree |
Spinal Diseases | 0.000542884 | 2 | 0 | BeFree |
Ankylosing spondylitis | 0.000542884 | 2 | 0 | BeFree |
Tuberculosis | 0.000542884 | 2 | 0 | BeFree |
Unipolar Depression | 0.000542884 | 2 | 0 | BeFree |
Varicocele | 0.000542884 | 2 | 0 | BeFree |
Fibromatosis, Aggressive | 0.000542884 | 2 | 0 | BeFree |
Atrophic condition of skin | 0.000542884 | 2 | 0 | BeFree |
Testicular hypogonadism | 0.000542884 | 2 | 0 | BeFree |
Cystadenocarcinoma, Serous | 0.000542884 | 2 | 0 | BeFree |
Ganglioglioma | 0.000542884 | 2 | 0 | BeFree |
Fibrous Dysplasia | 0.000542884 | 2 | 0 | BeFree |
Congenital hypoplasia of penis | 0.000542884 | 2 | 0 | BeFree |
Erythroblastosis | 0.000542884 | 2 | 0 | BeFree |
Invasive Lobular Breast Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Squamous cell carcinoma of esophagus | 0.000542884 | 2 | 0 | BeFree |
Cervix carcinoma | 0.000542884 | 2 | 0 | BeFree |
High-Grade Squamous Intraepithelial Lesions | 0.000542884 | 2 | 0 | BeFree |
Adenocarcinoma of colon | 0.000542884 | 2 | 0 | BeFree |
Congenital phimosis | 0.000542884 | 2 | 0 | BeFree |
Pallidoluysian degeneration | 0.000542884 | 2 | 0 | BeFree |
Acquired phimosis | 0.000542884 | 2 | 0 | BeFree |
Lupus Erythematosus | 0.000542884 | 2 | 0 | BeFree |
Adolescent idiopathic scoliosis | 0.000542884 | 2 | 0 | BeFree |
Motor symptoms | 0.000542884 | 2 | 0 | BeFree |
Reactive thrombocytosis | 0.000542884 | 2 | 0 | BeFree |
pseudohermaphrodite (non-specific) | 0.000542884 | 2 | 0 | BeFree |
Lower Urinary Tract Symptoms | 0.000542884 | 2 | 0 | BeFree |
Hereditary Breast and Ovarian Cancer Syndrome | 0.000542884 | 2 | 0 | BeFree |
Acne | 0.000542884 | 2 | 0 | BeFree |
Dentatorubral-Pallidoluysian Atrophy | 0.000542884 | 2 | 0 | BeFree |
Subfertility, Male | 0.000542884 | 2 | 0 | BeFree |
Invasive breast carcinoma | 0.000542884 | 2 | 0 | BeFree |
Sarcoma | 0.000542884 | 2 | 0 | BeFree |
Large cell neuroendocrine carcinoma | 0.000542884 | 2 | 0 | BeFree |
Salivary duct carcinoma | 0.000542884 | 2 | 0 | BeFree |
Cancer Cell Growth | 0.000542884 | 2 | 0 | BeFree |
Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Prostatic Hypertrophy | 0.000542884 | 2 | 0 | BeFree |
Testicular dysgenesis syndrome | 0.000542884 | 2 | 0 | BeFree |
Refractory anemia, without ringed sideroblasts, without excess blasts | 0.000542884 | 2 | 0 | BeFree |
Proliferative Inflammatory Atrophy | 0.000542884 | 2 | 0 | BeFree |
Prostatic Cancer, Castration-Resistant | 0.000542884 | 2 | 0 | BeFree |
Acquired Immunodeficiency Syndrome | 0.000271442 | 1 | 0 | BeFree |
Amenorrhea | 0.000271442 | 1 | 0 | BeFree |
Anaplasia | 0.000271442 | 1 | 0 | BeFree |
Aplastic Anemia | 0.000271442 | 1 | 0 | BeFree |
Anxiety Disorders | 0.000271442 | 1 | 0 | BeFree |
Aortic Aneurysm | 0.000271442 | 1 | 0 | BeFree |
Arthritis | 0.000271442 | 1 | 0 | BeFree |
Ataxia Telangiectasia | 0.000271442 | 1 | 0 | BeFree |
Ataxias, Hereditary | 0.000271442 | 1 | 0 | BeFree |
Carcinoid Tumor | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of skin | 0.000271442 | 1 | 0 | BeFree |
Non-Small Cell Lung Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Cardiomyopathy, Dilated | 0.000271442 | 1 | 0 | BeFree |
Malignant tumor of cervix | 0.000271442 | 1 | 0 | BeFree |
Decreased Libido | 0.000271442 | 1 | 0 | BeFree |
Diabetes Mellitus, Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
Endocrine System Diseases | 0.000271442 | 1 | 0 | BeFree |
Endometrial Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Eosinophilia | 0.000271442 | 1 | 0 | BeFree |
Breast Fibrocystic Disease | 0.000271442 | 1 | 0 | BeFree |
Fragile X Syndrome | 0.000271442 | 1 | 0 | BeFree |
Psychosexual identity disorder | 0.000271442 | 1 | 0 | BeFree |
Angiolymphoid hyperplasia | 0.000271442 | 1 | 0 | BeFree |
IGA Glomerulonephritis | 0.000271442 | 1 | 0 | BeFree |
Cardiac Arrest | 0.000271442 | 1 | 0 | BeFree |
Hodgkin Disease | 0.000271442 | 1 | 0 | BeFree |
Hydrophthalmos | 0.000271442 | 1 | 0 | BeFree |
Immunologic Deficiency Syndromes | 0.000271442 | 1 | 0 | BeFree |
Incontinence | 0.000271442 | 1 | 0 | BeFree |
Ischemia | 0.000271442 | 1 | 0 | BeFree |
Seborrheic keratosis | 0.000271442 | 1 | 0 | BeFree |
Kidney Calculi | 0.000271442 | 1 | 0 | BeFree |
Kidney Diseases | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
Leukemia, T-Cell | 0.000271442 | 1 | 0 | BeFree |
Liver Cirrhosis | 0.000271442 | 1 | 0 | BeFree |
Reticulosarcoma | 0.000271442 | 1 | 0 | BeFree |
Medulloblastoma | 0.000271442 | 1 | 0 | BeFree |
Mesothelioma | 0.000271442 | 1 | 0 | BeFree |
Multiple Myeloma | 0.000271442 | 1 | 0 | BeFree |
Muscular Dystrophy | 0.000271442 | 1 | 0 | BeFree |
Nephritis, Interstitial | 0.000271442 | 1 | 0 | BeFree |
neurofibroma | 0.000271442 | 1 | 0 | BeFree |
Acoustic Neuroma | 0.000271442 | 1 | 0 | BeFree |
Oculocerebrorenal Syndrome | 0.000271442 | 1 | 0 | BeFree |
Pain | 0.000271442 | 1 | 0 | BeFree |
Bullous pemphigoid | 0.000271442 | 1 | 0 | BeFree |
Peritonitis | 0.000271442 | 1 | 0 | BeFree |
Polycythemia Vera | 0.000271442 | 1 | 0 | BeFree |
prostatitis | 0.000271442 | 1 | 0 | BeFree |
Sarcoidosis | 0.000271442 | 1 | 0 | BeFree |
Supernumerary structure | 0.000271442 | 1 | 0 | BeFree |
Thymoma | 0.000271442 | 1 | 0 | BeFree |
Thyroiditis | 0.000271442 | 1 | 0 | BeFree |
Transsexualism | 0.000271442 | 1 | 0 | BeFree |
Wiskott-Aldrich Syndrome | 0.000271442 | 1 | 0 | BeFree |
Diffuse Large B-Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Polycystic Kidney, Autosomal Dominant | 0.000271442 | 1 | 0 | BeFree |
Polymyositis | 0.000271442 | 1 | 0 | BeFree |
Acute leukemia | 0.000271442 | 1 | 0 | BeFree |
Chronic sinusitis | 0.000271442 | 1 | 0 | BeFree |
Congenital heart block | 0.000271442 | 1 | 0 | BeFree |
Small cell carcinoma of lung | 0.000271442 | 1 | 0 | BeFree |
Acquired porencephaly | 0.000271442 | 1 | 0 | BeFree |
Adenocarcinoma of lung (disorder) | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of mouth | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of brain | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of endocrine gland | 0.000271442 | 1 | 0 | BeFree |
Secondary malignant neoplasm of lung | 0.000271442 | 1 | 0 | BeFree |
Hypertrophy of clitoris | 0.000271442 | 1 | 0 | BeFree |
Adrenoleukodystrophy | 0.000271442 | 1 | 0 | BeFree |
Liver Failure, Acute | 0.000271442 | 1 | 0 | BeFree |
Aicardi's syndrome | 0.000271442 | 1 | 0 | BeFree |
Ki-1+ Anaplastic Large Cell Lymphoma | 0.000271442 | 1 | 0 | BeFree |
Trophoblastic Tumor, Placental Site | 0.000271442 | 1 | 0 | BeFree |
Follicular thyroid carcinoma | 0.000271442 | 1 | 0 | BeFree |
Carcinoma, Lobular | 0.000271442 | 1 | 0 | BeFree |
Cystadenoma, Serous | 0.000271442 | 1 | 0 | BeFree |
Nerve Sheath Tumors | 0.000271442 | 1 | 0 | BeFree |
Lip and Oral Cavity Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Neurologic Symptoms | 0.000271442 | 1 | 0 | BeFree |
Congenital hernia | 0.000271442 | 1 | 0 | BeFree |
Pancreatic carcinoma | 0.000271442 | 1 | 0 | BeFree |
Disorder of male reproductive system | 0.000271442 | 1 | 0 | BeFree |
Hepatitis, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
Gonadal Dysgenesis, 45,X | 0.000271442 | 1 | 0 | BeFree |
Multiple tumors | 0.000271442 | 1 | 0 | BeFree |
Secondary pulmonary hypertension | 0.000271442 | 1 | 0 | BeFree |
Bilateral inguinal hernia | 0.000271442 | 1 | 0 | BeFree |
Vulvar Vestibulitis | 0.000271442 | 1 | 0 | BeFree |
Disorder of neutrophils | 0.000271442 | 1 | 0 | BeFree |
Virchow's node (disorder) | 0.000271442 | 1 | 0 | BeFree |
Carcinoma breast stage IV | 0.000271442 | 1 | 0 | BeFree |
Liver and Intrahepatic Biliary Tract Carcinoma | 0.000271442 | 1 | 0 | BeFree |
bilateral breast cancer | 0.000271442 | 1 | 0 | BeFree |
Focal Nodular Hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Lymphoid hyperplasia | 0.000271442 | 1 | 0 | BeFree |
Malignant Fibrous Histiocytoma | 0.000271442 | 1 | 0 | BeFree |
Histiocytic sarcoma | 0.000271442 | 1 | 0 | BeFree |
Summer-Type Hypersensitivity Pneumonitis | 0.000271442 | 1 | 0 | BeFree |
Idiopathic hirsutism | 0.000271442 | 1 | 0 | BeFree |
Deficiency of testosterone biosynthesis | 0.000271442 | 1 | 0 | BeFree |
Precocious pubarche | 0.000271442 | 1 | 0 | BeFree |
Carcinoma ex pleomorphic adenoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Malignant mesothelioma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of pancreas | 0.000271442 | 1 | 0 | BeFree |
Disseminated Malignant Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Common acute lymphoblastic leukemia | 0.000271442 | 1 | 0 | BeFree |
Juvenile Myelomonocytic Leukemia | 0.000271442 | 1 | 0 | BeFree |
Hematopoietic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Nephrolithiasis | 0.000271442 | 1 | 0 | BeFree |
Polyradiculoneuropathy, Chronic Inflammatory Demyelinating | 0.000271442 | 1 | 0 | BeFree |
Hereditary gingival fibromatosis | 0.000271442 | 1 | 0 | BeFree |
Female infertility associated with anovulation | 0.000271442 | 1 | 0 | BeFree |
Osteoarthritis, Knee | 0.000271442 | 1 | 0 | BeFree |
Neonatal Systemic lupus erythematosus | 0.000271442 | 1 | 0 | BeFree |
Impaired exercise tolerance | 0.000271442 | 1 | 0 | BeFree |
XX males | 0.000271442 | 1 | 0 | BeFree |
Hypospadias, perineal | 0.000271442 | 1 | 0 | BeFree |
Secondary malignant neoplasm of liver | 0.000271442 | 1 | 0 | BeFree |
Overweight | 0.000271442 | 1 | 0 | BeFree |
Mood Disorders | 0.000271442 | 1 | 0 | BeFree |
Recurrent Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Malignant Glioma | 0.000271442 | 1 | 0 | BeFree |
Congenital scoliosis | 0.000271442 | 1 | 0 | BeFree |
Loss of scalp hair | 0.000271442 | 1 | 0 | BeFree |
Leukemogenesis | 0.000271442 | 1 | 0 | BeFree |
Monocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Tumor Initiation | 0.000271442 | 1 | 0 | BeFree |
Terminal illness | 0.000271442 | 1 | 0 | BeFree |
Skin carcinoma | 0.000271442 | 1 | 0 | BeFree |
airway disease | 0.000271442 | 1 | 0 | BeFree |
Pyloric Stenosis, Hypertrophic | 0.000271442 | 1 | 0 | BeFree |
Subfertility | 0.000271442 | 1 | 0 | BeFree |
Poorly differentiated carcinoma | 0.000271442 | 1 | 0 | BeFree |
Biliary Tract Cancer | 0.000271442 | 1 | 0 | BeFree |
Primary malignant neoplasm of brain | 0.000271442 | 1 | 0 | BeFree |
Malignant Squamous Cell Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Heredodegenerative Disorders, Nervous System | 0.000271442 | 1 | 0 | BeFree |
Chromosome 11p deletion syndrome | 0.000271442 | 1 | 0 | BeFree |
Fat redistribution | 0.000271442 | 1 | 0 | BeFree |
Breast adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Cardiomyopathies | 0.000271442 | 1 | 0 | BeFree |
Erdheim-Chester Disease | 0.000271442 | 1 | 0 | BeFree |
Stromal Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Ischemic stroke | 0.000271442 | 1 | 0 | BeFree |
Denys-Drash Syndrome | 0.000271442 | 1 | 0 | BeFree |
Arthritis, Collagen-Induced | 0.000271442 | 1 | 0 | BeFree |
Mental Retardation, X-Linked | 0.000271442 | 1 | 0 | BeFree |
Endometrial adenocarcinoma | 0.000271442 | 1 | 0 | BeFree |
Ductal Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Intratubular malignant germ cells | 0.000271442 | 1 | 0 | BeFree |
X-Linked Combined Immunodeficiency Diseases | 0.000271442 | 1 | 0 | BeFree |
Small cell carcinoma of prostate | 0.000271442 | 1 | 0 | BeFree |
Eosinophilic disorder | 0.000271442 | 1 | 0 | BeFree |
Fibrous histiocytoma of tendon sheath | 0.000271442 | 1 | 0 | BeFree |
M5b Acute differentiated monocytic leukemia | 0.000271442 | 1 | 0 | BeFree |
Hereditary Malignant Neoplasm | 0.000271442 | 1 | 0 | BeFree |
Malignant Phyllodes Tumor of Prostate | 0.000271442 | 1 | 0 | BeFree |
Prostate Phyllodes Tumor | 0.000271442 | 1 | 0 | BeFree |
Sporadic Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Metastatic Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Autism Spectrum Disorders | 0.000271442 | 1 | 0 | BeFree |
Salivary Gland Pleomorphic Adenoma | 0.000271442 | 1 | 0 | BeFree |
Skin Carcinogenesis | 0.000271442 | 1 | 0 | BeFree |
Tumor-Associated Process | 0.000271442 | 1 | 0 | BeFree |
Tumor Angiogenesis | 0.000271442 | 1 | 0 | BeFree |
Glioblastoma Multiforme | 0.000271442 | 1 | 0 | BeFree |
Disorder characterized by eosinophilia | 0.000271442 | 1 | 0 | BeFree |
Carcinoma of Endocrine Gland | 0.000271442 | 1 | 0 | BeFree |
NEPHROLITHIASIS, CALCIUM OXALATE | 0.000271442 | 1 | 0 | BeFree |
NEUROTICISM | 0.000271442 | 1 | 0 | BeFree |
Azoospermia, Nonobstructive | 0.000271442 | 1 | 0 | BeFree |
LATERAL MENINGOCELE SYNDROME | 0.000271442 | 1 | 0 | BeFree |
Prostate Cancer, Hereditary, 7 | 0.000271442 | 1 | 0 | BeFree |
FRIEDREICH ATAXIA 1 | 0.000271442 | 1 | 0 | BeFree |
PORENCEPHALY, FAMILIAL | 0.000271442 | 1 | 0 | BeFree |
Philadelphia chromosome-positive acute lymphoblastic leukemia | 0.000271442 | 1 | 0 | BeFree |
Triple-Negative Breast Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Vestibulodynia | 0.000271442 | 1 | 0 | BeFree |
Sex Differentiation Disorders | 0.000271442 | 1 | 0 | BeFree |
46, XX Testicular Disorders of Sex Development | 0.000271442 | 1 | 0 | BeFree |
Limb ischemia | 0.000271442 | 1 | 0 | BeFree |
Cervical Intraepithelial Neoplasia Grade 2/3 | 0.000271442 | 1 | 0 | BeFree |
Dysplastic nodule | 0.000271442 | 1 | 0 | BeFree |
Ischemic Cerebrovascular Accident | 0.000271442 | 1 | 0 | BeFree |
Sclerosing Polycystic Adenosis | 0.000271442 | 1 | 0 | BeFree |
Juvenile arthritis | 0.000271442 | 1 | 0 | BeFree |
Neutrophilia (disorder) | 0.000271442 | 1 | 0 | BeFree |
Juvenile rheumatoid arthritis | 0.000271442 | 1 | 0 | BeFree |
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