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APP基因(以及对应的蛋白质)的细胞分布位置:
APP基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Alzheimer's Disease | 0.600803935 | 269 | 6 | BeFree_CLINVAR_CTD_human_GAD_LHGDN_MGD_UNIPROT |
CEREBRAL AMYLOID ANGIOPATHY, APP-RELATED | 0.48 | 4 | 4 | CLINVAR_CTD_human_ORPHANET_UNIPROT |
Cerebral hemorrhage with amyloidosis, hereditary, Dutch type | 0.24 | 2 | 0 | CTD_human_ORPHANET |
Dementia | 0.150676439 | 33 | 2 | BeFree_CTD_human_GAD_LHGDN |
Down Syndrome | 0.146866321 | 27 | 0 | BeFree_CTD_human_GAD_LHGDN |
Cerebral Amyloid Angiopathy | 0.142870638 | 20 | 1 | BeFree_CTD_human_LHGDN |
Plaque, Amyloid | 0.141172466 | 79 | 2 | BeFree_CTD_human |
Amyloidosis | 0.134416214 | 27 | 0 | BeFree_CTD_human_LHGDN |
Neurodegenerative Disorders | 0.121628651 | 8 | 0 | BeFree_CTD_human |
Anxiety Disorders | 0.121357209 | 5 | 1 | BeFree_CTD_human |
Mild cognitive disorder | 0.121357209 | 6 | 0 | BeFree_CTD_human |
Hereditary Cerebral Amyloid Angiopathy, Dutch Type | 0.121085767 | 4 | 0 | BeFree_ORPHANET |
Amnesia | 0.120814326 | 4 | 0 | BeFree_CTD_human |
Fragile X Syndrome | 0.120271442 | 2 | 0 | BeFree_CTD_human |
Brain Diseases | 0.12 | 1 | 0 | CTD_human |
Cognition Disorders | 0.12 | 4 | 0 | CTD_human |
Learning Disorders | 0.12 | 5 | 0 | CTD_human |
Memory Disorders | 0.12 | 9 | 0 | CTD_human |
Necrosis | 0.12 | 1 | 0 | CTD_human |
Nerve Degeneration | 0.12 | 11 | 0 | CTD_human |
Spinal Cord Diseases | 0.12 | 1 | 0 | CTD_human |
Weight Gain | 0.12 | 1 | 0 | CTD_human |
Muscle Weakness | 0.12 | 1 | 0 | CTD_human |
Premature aging syndrome | 0.12 | 1 | 0 | CTD_human |
Paralysed | 0.12 | 4 | 0 | CTD_human |
Neurogenic Inflammation | 0.12 | 2 | 0 | CTD_human |
ALZHEIMER DISEASE, FAMILIAL, 1 | 0.12 | 0 | 11 | CLINVAR |
Alzheimer Disease, Early-Onset, With Cerebral Amyloid Angiopathy | 0.12 | 0 | 0 | CLINVAR |
Iron deficiency anemia | 0.08 | 1 | 0 | RGD |
Senile Plaques | 0.03040149 | 112 | 2 | BeFree |
Cerebral Hemorrhage | 0.010540083 | 4 | 0 | GAD_LHGDN |
Memory impairment | 0.009500466 | 35 | 0 | BeFree |
Lewy Body Disease | 0.008444493 | 4 | 0 | BeFree_LHGDN |
Presenile dementia | 0.007057489 | 26 | 2 | BeFree |
Amyotrophic Lateral Sclerosis | 0.005991584 | 4 | 1 | BeFree_LHGDN |
Impaired cognition | 0.005971721 | 22 | 2 | BeFree |
Neuroblastoma | 0.005700279 | 21 | 0 | BeFree |
Central neuroblastoma | 0.005700279 | 21 | 0 | BeFree |
Cessation of life | 0.0054487 | 2 | 0 | LHGDN |
Inflammation | 0.0054487 | 2 | 0 | LHGDN |
Familial Alzheimer Disease (FAD) | 0.005157396 | 19 | 2 | BeFree |
Neurofibrillary degeneration (morphologic abnormality) | 0.004885954 | 18 | 0 | BeFree |
melanoma | 0.003538676 | 4 | 0 | BeFree_LHGDN |
Aortic Aneurysm, Abdominal | 0.003528744 | 13 | 0 | BeFree |
AURAL ATRESIA, CONGENITAL | 0.003528744 | 13 | 0 | BeFree |
Encephalitis | 0.003267234 | 3 | 0 | BeFree_LHGDN |
Aneurysm | 0.003257302 | 12 | 0 | BeFree |
Glioblastoma | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Amyloid Neuropathies, Familial | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Cardiovascular Diseases | 0.002909916 | 3 | 0 | BeFree_GAD |
Frontotemporal dementia | 0.002909916 | 3 | 0 | BeFree_GAD |
Anoxia | 0.00272435 | 1 | 0 | LHGDN |
Hereditary Nonpolyposis Colorectal Neoplasms | 0.00272435 | 1 | 0 | LHGDN |
leukemia | 0.00272435 | 1 | 0 | LHGDN |
Prion Diseases | 0.00272435 | 1 | 0 | LHGDN |
Infection | 0.00272435 | 1 | 0 | LHGDN |
Arteriosclerosis | 0.002638474 | 2 | 0 | BeFree_GAD |
Age related macular degeneration | 0.002638474 | 2 | 0 | BeFree_GAD |
Amyloidosis, Familial | 0.002638474 | 2 | 0 | BeFree_GAD |
Oppositional Defiant Disorder | 0.002367032 | 1 | 0 | GAD |
Tobacco Use Disorder | 0.002367032 | 1 | 0 | GAD |
Attention Deficit Disorder | 0.002367032 | 1 | 0 | GAD |
Conduct Disorder | 0.002367032 | 1 | 0 | GAD |
Alzheimer Disease, Early Onset | 0.001900093 | 7 | 1 | BeFree |
Spastic Paraplegia, Hereditary | 0.001628651 | 6 | 0 | BeFree |
Aortic Aneurysm, Thoracic | 0.001628651 | 6 | 0 | BeFree |
Aortic Aneurysm | 0.001357209 | 5 | 0 | BeFree |
HIV Infections | 0.001357209 | 5 | 0 | BeFree |
Diabetes | 0.001085767 | 4 | 0 | BeFree |
Diabetes Mellitus | 0.001085767 | 4 | 0 | BeFree |
Dystonia | 0.001085767 | 4 | 0 | BeFree |
Cerebrovascular accident | 0.001085767 | 4 | 1 | BeFree |
Dystonia Disorders | 0.001085767 | 4 | 0 | BeFree |
Alzheimer Disease, Late Onset | 0.001085767 | 4 | 0 | BeFree |
Cerebral Amyloid Angiopathy, Hereditary | 0.001085767 | 4 | 2 | BeFree |
Malignant neoplasm of breast | 0.000814326 | 3 | 0 | BeFree |
Myopathy | 0.000814326 | 3 | 0 | BeFree |
Obesity | 0.000814326 | 3 | 1 | BeFree |
Trisomy | 0.000814326 | 3 | 0 | BeFree |
Vascular Diseases | 0.000814326 | 3 | 0 | BeFree |
Pick Disease of the Brain | 0.000814326 | 3 | 0 | BeFree |
Breast Carcinoma | 0.000814326 | 3 | 0 | BeFree |
Memory Loss | 0.000814326 | 3 | 0 | BeFree |
Primary biliary cirrhosis | 0.000542884 | 2 | 0 | BeFree |
Malignant neoplasm of stomach | 0.000542884 | 2 | 0 | BeFree |
Parkinson Disease | 0.000542884 | 2 | 0 | BeFree |
Seizures | 0.000542884 | 2 | 0 | BeFree |
Septicemia | 0.000542884 | 2 | 0 | BeFree |
Motor Neuron Disease | 0.000542884 | 2 | 0 | BeFree |
Cerebral atrophy | 0.000542884 | 2 | 0 | BeFree |
Inclusion Body Myositis (disorder) | 0.000542884 | 2 | 0 | BeFree |
Sepsis | 0.000542884 | 2 | 0 | BeFree |
Familial Cerebral Amyloid Angiopathy | 0.000542884 | 2 | 0 | BeFree |
Impaired glucose tolerance | 0.000542884 | 2 | 1 | BeFree |
Atherosclerotic occlusive disease | 0.000542884 | 2 | 0 | BeFree |
Carcinogenesis | 0.000542884 | 2 | 0 | BeFree |
Stomach Carcinoma | 0.000542884 | 2 | 0 | BeFree |
Peroxisome biogenesis disorders | 0.000542884 | 2 | 0 | BeFree |
Dementia, familial Danish | 0.000542884 | 2 | 0 | BeFree |
AMYOTROPHIC LATERAL SCLEROSIS 1 | 0.000542884 | 2 | 0 | BeFree |
Liver carcinoma | 0.000542884 | 2 | 0 | BeFree |
Rheumatoid Arthritis | 0.000271442 | 1 | 0 | BeFree |
Asthma | 0.000271442 | 1 | 0 | BeFree |
Atherosclerosis | 0.000271442 | 1 | 0 | BeFree |
Autistic Disorder | 0.000271442 | 1 | 0 | BeFree |
Azoospermia | 0.000271442 | 1 | 1 | BeFree |
Bacteremia | 0.000271442 | 1 | 0 | BeFree |
Bipolar Disorder | 0.000271442 | 1 | 0 | BeFree |
Colitis | 0.000271442 | 1 | 0 | BeFree |
Colonic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Multi-infarct dementia | 0.000271442 | 1 | 0 | BeFree |
Senile dementia | 0.000271442 | 1 | 0 | BeFree |
Dementia, Vascular | 0.000271442 | 1 | 0 | BeFree |
Diabetes Mellitus, Insulin-Dependent | 0.000271442 | 1 | 0 | BeFree |
Fanconi Anemia | 0.000271442 | 1 | 0 | BeFree |
Fatigue | 0.000271442 | 1 | 0 | BeFree |
Gingival Diseases | 0.000271442 | 1 | 0 | BeFree |
Hamartoma Syndrome, Multiple | 0.000271442 | 1 | 0 | BeFree |
Headache | 0.000271442 | 1 | 0 | BeFree |
Herpes Simplex Infections | 0.000271442 | 1 | 0 | BeFree |
Hydrocephalus, Normal Pressure | 0.000271442 | 1 | 0 | BeFree |
Hypertensive disease | 0.000271442 | 1 | 0 | BeFree |
Hyperthyroidism | 0.000271442 | 1 | 0 | BeFree |
Hypothyroidism | 0.000271442 | 1 | 0 | BeFree |
Male infertility | 0.000271442 | 1 | 1 | BeFree |
Ischemia | 0.000271442 | 1 | 0 | BeFree |
Leukemia, Myelocytic, Acute | 0.000271442 | 1 | 0 | BeFree |
Liver neoplasms | 0.000271442 | 1 | 0 | BeFree |
Moyamoya Disease | 0.000271442 | 1 | 0 | BeFree |
Neoplasm Metastasis | 0.000271442 | 1 | 0 | BeFree |
nervous system disorder | 0.000271442 | 1 | 0 | BeFree |
Osteitis Deformans | 0.000271442 | 1 | 0 | BeFree |
Degenerative polyarthritis | 0.000271442 | 1 | 0 | BeFree |
Ovarian Diseases | 0.000271442 | 1 | 0 | BeFree |
Periodontal Diseases | 0.000271442 | 1 | 0 | BeFree |
Phenylketonurias | 0.000271442 | 1 | 0 | BeFree |
Plague | 0.000271442 | 1 | 0 | BeFree |
polyps | 0.000271442 | 1 | 0 | BeFree |
Psoriasis | 0.000271442 | 1 | 0 | BeFree |
Psychotic Disorders | 0.000271442 | 1 | 0 | BeFree |
Kidney Failure | 0.000271442 | 1 | 0 | BeFree |
Schizophrenia | 0.000271442 | 1 | 0 | BeFree |
Tachycardia | 0.000271442 | 1 | 0 | BeFree |
Tetanus | 0.000271442 | 1 | 0 | BeFree |
Tuberous Sclerosis | 0.000271442 | 1 | 0 | BeFree |
Unipolar Depression | 0.000271442 | 1 | 0 | BeFree |
Polyendocrinopathies, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
Hypokinesia | 0.000271442 | 1 | 0 | BeFree |
Cataract | 0.000271442 | 1 | 0 | BeFree |
Joint swelling | 0.000271442 | 1 | 0 | BeFree |
Tumor Progression | 0.000271442 | 1 | 0 | BeFree |
Germ cell tumor | 0.000271442 | 1 | 0 | BeFree |
General Paralysis | 0.000271442 | 1 | 0 | BeFree |
Niemann-Pick Disease, Type C | 0.000271442 | 1 | 0 | BeFree |
Age-related cognitive decline | 0.000271442 | 1 | 0 | BeFree |
Hepatitis, Autoimmune | 0.000271442 | 1 | 0 | BeFree |
Cerebellar degeneration | 0.000271442 | 1 | 0 | BeFree |
Carotid artery occlusion | 0.000271442 | 1 | 0 | BeFree |
Pili torti-deafness syndrome | 0.000271442 | 1 | 0 | BeFree |
Chronic Periodontitis | 0.000271442 | 1 | 0 | BeFree |
Cortical cataract | 0.000271442 | 1 | 2 | BeFree |
Carcinoma breast stage IV | 0.000271442 | 1 | 0 | BeFree |
Microaneurysm | 0.000271442 | 1 | 0 | BeFree |
Mural thrombus | 0.000271442 | 1 | 0 | BeFree |
Microembolus | 0.000271442 | 1 | 0 | BeFree |
Nicotinamide adenine dinucleotide coenzyme Q reductase deficiency | 0.000271442 | 1 | 0 | BeFree |
Nonorganic psychosis | 0.000271442 | 1 | 0 | BeFree |
Metabolic Syndrome X | 0.000271442 | 1 | 0 | BeFree |
Neurobehavioral Manifestations | 0.000271442 | 1 | 0 | BeFree |
3-Methylglutaconic aciduria type 2 | 0.000271442 | 1 | 0 | BeFree |
Leukemogenesis | 0.000271442 | 1 | 0 | BeFree |
Progressive Neoplastic Disease | 0.000271442 | 1 | 0 | BeFree |
temporal pain | 0.000271442 | 1 | 5 | BeFree |
Frontotemporal Lobar Degeneration | 0.000271442 | 1 | 0 | BeFree |
Classical phenylketonuria | 0.000271442 | 1 | 0 | BeFree |
Carotid Artery Plaque | 0.000271442 | 1 | 0 | BeFree |
Mural thrombus of heart | 0.000271442 | 1 | 0 | BeFree |
Attention deficit hyperactivity disorder | 0.000271442 | 1 | 0 | BeFree |
Poorly Differentiated Thyroid Carcinoma | 0.000271442 | 1 | 0 | BeFree |
Major Depressive Disorder | 0.000271442 | 1 | 0 | BeFree |
Liver regeneration disorder | 0.000271442 | 1 | 0 | BeFree |
CODAS syndrome | 0.000271442 | 1 | 0 | BeFree |
Spastic Ataxia | 0.000271442 | 1 | 0 | BeFree |
DYSTONIA 1, TORSION, AUTOSOMAL DOMINANT | 0.000271442 | 1 | 0 | BeFree |
Dementia, familial British | 0.000271442 | 1 | 0 | BeFree |
Coronary Artery Disease | 0.000271442 | 1 | 0 | BeFree |
Moyamoya disease 1 | 0.000271442 | 1 | 0 | BeFree |
Progressive cGVHD | 0.000271442 | 1 | 0 | BeFree |
Zellweger Spectrum | 0.000271442 | 1 | 0 | BeFree |
Spastic Paraplegia Type 7 | 0.000271442 | 1 | 0 | BeFree |
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