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This gene encodes a component of high density lipoprotein that has no marked similarity to other apolipoprotein sequences. It has a high degree of homology to plasma retinol-binding protein and other members of the alpha 2 microglobulin protein superfamily of carrier proteins, also known as lipocalins. This glycoprotein is closely associated with the enzyme lecithin:cholesterol acyltransferase - an enzyme involved in lipoprotein metabolism. [provided by RefSeq, Aug 2008]
[中文简述(自动翻译):]  这个基因编码具有没有显着相似性的其他载脂蛋白序列高密度脂蛋白的组分。它具有血浆视黄醇结合蛋白和载体蛋白,也称为脂笼蛋白的α2微球蛋白的蛋白质超家族的其他成员具有高度的同源性。这种糖蛋白是紧密地与酶卵磷脂关联:胆固醇酰基转移酶 - 参与脂蛋白代谢的酶。 [由RefSeq的,2008年8月提供]
APOD基因(以及对应的蛋白质)的细胞分布位置:
APOD基因的本体(GO)信息:
疾病名称 | 关系值 | NofPmids | NofSnps | 来源 |
Glioma | 0.120271442 | 1 | 0 | BeFree_CTD_human |
Learning Disorders | 0.12 | 1 | 0 | CTD_human |
Hypokinesia | 0.12 | 1 | 0 | CTD_human |
Neurodegenerative Disorders | 0.12 | 1 | 0 | CTD_human |
Cerebrovascular accident | 0.080271442 | 2 | 0 | BeFree_RGD |
Status Epilepticus | 0.08 | 1 | 0 | RGD |
Impotence, Vasculogenic | 0.08 | 1 | 0 | RGD |
Alzheimer's Disease | 0.020908413 | 5 | 0 | BeFree_GAD_LHGDN |
Schizophrenia | 0.00617715 | 5 | 0 | BeFree_GAD_LHGDN |
Inflammation | 0.005091382 | 2 | 0 | GAD_LHGDN |
Encephalitis | 0.002995792 | 1 | 0 | BeFree_LHGDN |
Parkinson Disease | 0.002995792 | 2 | 0 | BeFree_LHGDN |
Diabetes Mellitus, Non-Insulin-Dependent | 0.002909916 | 2 | 0 | BeFree_GAD |
fibroma | 0.00272435 | 1 | 0 | LHGDN |
Dermatofibrosarcoma | 0.00272435 | 1 | 0 | LHGDN |
Coronary heart disease | 0.002638474 | 2 | 0 | BeFree_GAD |
Insulin Resistance | 0.002367032 | 1 | 0 | GAD |
Malignant neoplasm of breast | 0.001085767 | 4 | 0 | BeFree |
Breast Carcinoma | 0.001085767 | 4 | 0 | BeFree |
Mental disorders | 0.000542884 | 2 | 0 | BeFree |
Colorectal Carcinoma | 0.000542884 | 2 | 0 | BeFree |
nervous system disorder | 0.000542884 | 2 | 0 | BeFree |
Neurofibrillary degeneration (morphologic abnormality) | 0.000542884 | 2 | 0 | BeFree |
Anaplastic astrocytoma | 0.000542884 | 2 | 0 | BeFree |
Colorectal Cancer | 0.000542884 | 2 | 0 | BeFree |
Adenoma | 0.000271442 | 1 | 0 | BeFree |
Fatty Liver | 0.000271442 | 1 | 0 | BeFree |
Breast Fibrocystic Disease | 0.000271442 | 1 | 0 | BeFree |
Heart failure | 0.000271442 | 1 | 0 | BeFree |
Congestive heart failure | 0.000271442 | 1 | 0 | BeFree |
Hyperinsulinism | 0.000271442 | 1 | 0 | BeFree |
Multiple Sclerosis | 0.000271442 | 1 | 0 | BeFree |
Neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
Obesity | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma | 0.000271442 | 1 | 0 | BeFree |
Prostatic Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Androgen-Insensitivity Syndrome | 0.000271442 | 1 | 0 | BeFree |
Central Nervous System Neoplasms | 0.000271442 | 1 | 0 | BeFree |
Microvascular Angina | 0.000271442 | 1 | 0 | BeFree |
Bromhidrosis | 0.000271442 | 1 | 0 | BeFree |
Reifenstein Syndrome | 0.000271442 | 1 | 0 | BeFree |
stage, prostate cancer | 0.000271442 | 1 | 0 | BeFree |
Pilocytic Astrocytoma | 0.000271442 | 1 | 0 | BeFree |
Malignant neoplasm of prostate | 0.000271442 | 1 | 0 | BeFree |
Alzheimer Disease, Late Onset | 0.000271442 | 1 | 0 | BeFree |
Osteosarcoma of bone | 0.000271442 | 1 | 0 | BeFree |
Prostate carcinoma | 0.000271442 | 1 | 0 | BeFree |
Secondary malignant neoplasm of lymph node | 0.000271442 | 1 | 0 | BeFree |
Central neuroblastoma | 0.000271442 | 1 | 0 | BeFree |
Testicular Feminization | 0.000271442 | 1 | 0 | BeFree |
Tauopathies | 0.000271442 | 1 | 0 | BeFree |
High-Grade Prostatic Intraepithelial Neoplasia | 0.000271442 | 1 | 0 | BeFree |
Non-Neoplastic Disorder | 0.000271442 | 1 | 0 | BeFree |
Liver carcinoma | 0.000271442 | 1 | 0 | BeFree |
Steatohepatitis | 0.000271442 | 1 | 0 | BeFree |
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