AP1S2(adaptor-related protein complex 1, sigma 2 subunit) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

Xp22
基因染色体位置图

基因简述

基因简述

Adaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2013]

[中文简述(自动翻译):]  适配器蛋白复合物1在位于高尔基复合体，在那里它介导网格蛋白的至膜既招募和跨膜受体的胞质尾部内分选信号的识别涂覆囊泡的胞质面找到。这种复杂的是两个大，一个媒体，一个小adaptin亚基组成的异四聚体。由该基因编码的蛋白质可作为这种复杂的小亚基，并且是adaptin蛋白家族的一个成员。已发现该基因编码不同亚型抄本变形。 [由RefSeq的，2013年1月提供]

OMIM数据库中对AP1S2基因的介绍     Wikipedia数据库中对AP1S2基因的介绍

基因序列

基因序列

AP1S2基因的碱基序列：[NCBI]

基因突变

基因突变

AP1S2基因的碱基突变：           显示全部snp
rs869285594       rs781729328       rs781722023       rs781721200       rs781663464       rs781639167       rs781486489       rs781538228       rs781486175       rs781317452       rs781243066       rs781027153       rs781056895       rs780976525       rs780970976       rs780740364       rs780614117       rs780580566       rs780322529       rs780308831       rs780122192       rs780107799       rs780117399       rs780101139       rs780051708       rs780043511       rs779927273       rs779620700       rs779430035       rs779294539       rs779275714       rs779160574       rs779122926       rs779011616       rs778791472       rs778789721       rs778700579      
rs778337435       rs778337346       rs778244611       rs778212647       rs778191033       rs777874897       rs777786921       rs777581703       rs777280863       rs777218950       rs777111607       rs776984122       rs776982383       rs776832857       rs776927226       rs776583785       rs776479167       rs776474326       rs776346522       rs775923167       rs776309078       rs775841567       rs775768709       rs775496703       rs775459477       rs775448013       rs775364128       rs775276736       rs775092677       rs775066613       rs774966674       rs774792933       rs774765662       rs774486967       rs774629716       rs774344849       rs774341609       rs774166253       rs774138905       rs774136998       rs773966134       rs773958016       rs773658607       rs773639596       rs773621681       rs773535000       rs773123187       rs773265343       rs773116073       rs772965410       rs772911936       rs772833222       rs772683061       rs772734475       rs772657751       rs772453110       rs772341931       rs772166461       rs772219283       rs772031451       rs771941718       rs771658762       rs771614736       rs771497073       rs771450787       rs771475951       rs771387203       rs771351036       rs771279111       rs771117607       rs770804791       rs771024691       rs770795672       rs770732699       rs770683935       rs770517417       rs770504419       rs770480303       rs770320852       rs770199415       rs770262016       rs770076294       rs769906994       rs769643439       rs769602850       rs769499933       rs769397153       rs769444281       rs769373487       rs769371346       rs769220812       rs769244525       rs769132550       rs768949115       rs768890458       rs768772768       rs768714374       rs768675757       rs768611577       rs768427454       rs768384012       rs768149575       rs768089171       rs768036208       rs767774837       rs767704112       rs767506073       rs767305779       rs767384625       rs767277961       rs767179437       rs767055780       rs766995389       rs766833254       rs766802119       rs766767472       rs766718606       rs766440462       rs766440267       rs766408461       rs766209479       rs766200992       rs766149436       rs766049012       rs766141545       rs766027688       rs766000710       rs765854509       rs765638604       rs765569308       rs765416110       rs765231661       rs765005578       rs764983427       rs764846381       rs764798636       rs764752230       rs764724837       rs764716237       rs764686581       rs764679302       rs764484656       rs764483318       rs764325294       rs764295767       rs764063680       rs763821712       rs763763141       rs763717703       rs763565186       rs763508032       rs763252203       rs763125426       rs763084760       rs762747425       rs762733561       rs762709442       rs762599108       rs762486460       rs762438736       rs762372007       rs762083571       rs761874950       rs761850993       rs761796031       rs761779751       rs761607323       rs761573359       rs761484262       rs761438999       rs761415737       rs761386546       rs761302161       rs761160702       rs761135162       rs761041750       rs760915867       rs760660416       rs760700264       rs760538854       rs760511267       rs760479987       rs760306529       rs760281928       rs760072646       rs759869005       rs759762734       rs759601651       rs759476610       rs759340504       rs759323753       rs759184708       rs759178404       rs759156501       rs759073386       rs759089622       rs758840126       rs758681457       rs758784348       rs758673079       rs758471856       rs758080058       rs757951819       rs757896810       rs757692060       rs757254610       rs757225550       rs757161457       rs757069069       rs757157931       rs756756184       rs756993043       rs756612753       rs756611119       rs756443305       rs756346284       rs756335561       rs756310367       rs756134915       rs756133992       rs756075475       rs755971183       rs755956212       rs755826541       rs755794453       rs755437405       rs755378238       rs755358393       rs755205305       rs755163768       rs755082763       rs755097269       rs754961043       rs755046023       rs754954695       rs754786510       rs754761928       rs754662452       rs754627019       rs754587538       rs754534498       rs754494976       rs754176077       rs754129318       rs753935383       rs753820519       rs753697865       rs753372323       rs753239020       rs752962387       rs752708433       rs752785754       rs752849887       rs752537051       rs752409871       rs752384379       rs752224937       rs752155741       rs752102468       rs752081005       rs751786781       rs751859066       rs751591743       rs751546908       rs751485290       rs751256743       rs751253080       rs751057640       rs751023908       rs750988637       rs750876719       rs750785485       rs750727708       rs750603516       rs750553423       rs750521403       rs750314808       rs750268777       rs750241601       rs750122067       rs750033646       rs749930706       rs749881573       rs749618551       rs749708694       rs749504275       rs749490033       rs749486287       rs749351171       rs749281615       rs749184417       rs749017490       rs748891157       rs748784846       rs748641287       rs748566663       rs748041023       rs748565291       rs748019352       rs747872851       rs747872072       rs747739183       rs747711716       rs747569393       rs747531404       rs747450282       rs747408331       rs747298493       rs747167886       rs747043868       rs747059594       rs747038183       rs746895190       rs746781373       rs746682583       rs746437244       rs746421314       rs746298707       rs746237772       rs746219819       rs746145941       rs746104268       rs745943807       rs745884033       rs745917077       rs745882887       rs745450350       rs745344000       rs578050544       rs573328580       rs567453103       rs561264587       rs553162741       rs542901066       rs540433304       rs528636438       rs377210898       rs377529228       rs376525848       rs376685147       rs376217003       rs375816022       rs374652740       rs373565011       rs373093781       rs372822299       rs371886005       rs370352076       rs368784561       rs369699155       rs368156550       rs202012751       rs201372069       rs201233466       rs200944886       rs200941651       rs200662353       rs200535163       rs200525006       rs200146767       rs199896672       rs199871378       rs199661808       rs199590963       rs193271719       rs193180393       rs192878722       rs192600884       rs192306158       rs192291108       rs192172204       rs192141538       rs191930800       rs191905246       rs191851165       rs191845880       rs191737999       rs191608692       rs191281962       rs191188407       rs191072520       rs190986936       rs190676541       rs190612724       rs190602798       rs190283275       rs190127906       rs189994098       rs189978834       rs189742366       rs189695640       rs189678890       rs189455144       rs189364962       rs189351223       rs189237788       rs189075409       rs188861324       rs188571298       rs188453937       rs188420447       rs188307562       rs188221731       rs188172592       rs188098086       rs187917527       rs187909844       rs187812892       rs187591981       rs187557838       rs187555082       rs187552494       rs187324645       rs187068051       rs187004706       rs186994452       rs186991215       rs186853190       rs186523071       rs186517866       rs186400066       rs186308344       rs186192450       rs186165818       rs185576012       rs185150940       rs185145573       rs185015171       rs184906886       rs184826215       rs184732978       rs184699321       rs184687220       rs184490682       rs184356369       rs183945873       rs183783075       rs183778516       rs183704139       rs183658313       rs183319253       rs183189298       rs183176745       rs183071843       rs182698330       rs182901105       rs182673388       rs182317241       rs182227525       rs182146360       rs182117377       rs181964422       rs181873012       rs181687989       rs181489997       rs181448056       rs181444695       rs181337386       rs181150012       rs181057898       rs181039537       rs180701556       rs180674230       rs151337282       rs151209698       rs150829208       rs149774242       rs149711911       rs149236916       rs149178321       rs148367711       rs147715616       rs147285449       rs147146022       rs147089371       rs146903987       rs146286369       rs146015714       rs146003556       rs145737243       rs144700765       rs144579474       rs144203327       rs144182877       rs143372353       rs143031717       rs142670324       rs142652104       rs142528497       rs142438040       rs142340628       rs141789871       rs141399880       rs140198686       rs140466743       rs139491879       rs138664671       rs138370893       rs138327293       rs137964366       rs137903796       rs115811578       rs115634760       rs113802903       rs113498543       rs113465225       rs113272393       rs112635400       rs112067919       rs111706264       rs111503739       rs76439951       rs77260076       rs73635837       rs73635836       rs73441993       rs73202857       rs73202855       rs73202852       rs72614602       rs61741688       rs59216799       rs58890583       rs57440814       rs41309677       rs56876815       rs35656473       rs34644010       rs17216806       rs13440876       rs12156975       rs12009071       rs12156972       rs11559236       rs11385838       rs11355576       rs10616572       rs7892479       rs7881484       rs7878362       rs7066721       rs7061714       rs6632751       rs5980197       rs5936069       rs5936068       rs5936067       rs5936066       rs5934283       rs4830998       rs4830997       rs4830996       rs4830550       rs3788931       rs3788929       rs3761617       rs3048672       rs2795104       rs2523002       rs2214428       rs2189277       rs2040722       rs1064868       rs1858559       rs798180       rs798179       rs798178       rs798177       rs798169       rs798168       rs798167       rs798166       rs764990       rs3652      

基因表达

基因表达

AP1S2基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
GGACAATGAACTAATTACCCTGG
59
TAGTTCACAGACACTGCCG
60
CTCACATTTAATAGATGCCACG
58
GAAATTCTGCATACTCGATGAG
58
CACATTTAATAGATGCCACGTC
58
CTGTGAAATTCTGCATACTCG
58
GGACAATGAACTAATTACCCTGG
59
TCTAGTTCACAGACACTGCC
60
CACATTTAATAGATGCCACGTC
58
CTGTGAAATTCTGCATACTCGA
59
CAGGACAATGAACTAATTACCCTG
60
TAGTTCACAGACACTGCCG
60

转录因子

转录因子

      尚未收录相关数据

基因本体信息

AP1S2基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

AP1S2基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0006886
A6NH01(UniProtKB)
IEA
GO:0008565
A6NH01(UniProtKB)
IEA
GO:0016192
A6NH01(UniProtKB)
IEA
GO:0030117
A6NH01(UniProtKB)
IEA
GO:0006886
F6SFB5(UniProtKB)
IEA
GO:0008565
F6SFB5(UniProtKB)
IEA
GO:0016192
F6SFB5(UniProtKB)
IEA
GO:0030117
F6SFB5(UniProtKB)
IEA
GO:0006886
H0Y673(UniProtKB)
IEA
GO:0008565
H0Y673(UniProtKB)
IEA
GO:0016192
H0Y673(UniProtKB)
IEA
GO:0030117
H0Y673(UniProtKB)
IEA
GO:0006886
H7BZG6(UniProtKB)
IEA
GO:0008565
H7BZG6(UniProtKB)
IEA
GO:0016192
H7BZG6(UniProtKB)
IEA
GO:0030117
H7BZG6(UniProtKB)
IEA
GO:0000139
P56377(UniProtKB)
TAS
GO:0000139
P56377(UniProtKB)
TAS
GO:0000139
P56377(UniProtKB)
TAS
GO:0000139
P56377(UniProtKB)
TAS
GO:0000139
P56377(UniProtKB)
TAS
GO:0000139
P56377(UniProtKB)
TAS
GO:0005515
P56377(UniProtKB)
IPI
GO:0005765
P56377(UniProtKB)
TAS
GO:0005765
P56377(UniProtKB)
TAS
GO:0005794
P56377(UniProtKB)
IDA
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005829
P56377(UniProtKB)
TAS
GO:0005905
P56377(UniProtKB)
IEA
GO:0006886
P56377(UniProtKB)
IEA
GO:0008565
P56377(UniProtKB)
IEA
GO:0016192
P56377(UniProtKB)
IEA
GO:0019886
P56377(UniProtKB)
TAS
GO:0030119
P56377(UniProtKB)
TAS
GO:0030659
P56377(UniProtKB)
TAS
GO:0030659
P56377(UniProtKB)
TAS
GO:0030669
P56377(UniProtKB)
TAS
GO:0032588
P56377(UniProtKB)
TAS
GO:0032588
P56377(UniProtKB)
TAS
GO:0032588
P56377(UniProtKB)
TAS
GO:0032588
P56377(UniProtKB)
TAS
GO:0043231
P56377(UniProtKB)
IDA
GO:0050690
P56377(UniProtKB)
TAS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控AP1S2基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
DANDY-WALKER MALFORMATION WITH MENTAL RETARDATION, BASAL GANGLIA DISEASE, AND SEIZURES 0.440271442 3 6 BeFree_CLINVAR_CTD_human_MGD_ORPHANET
Mental Retardation, X-Linked 0.001085767 4 0 BeFree
Mental Retardation 0.000542884 2 0 BeFree
Muscle hypotonia 0.000542884 2 0 BeFree
Malignant neoplasm of prostate 0.000542884 2 0 BeFree
Prostate carcinoma 0.000542884 2 0 BeFree
Autistic Disorder 0.000271442 1 0 BeFree
Dandy-Walker Syndrome 0.000271442 1 0 BeFree
Hydrocephalus 0.000271442 1 0 BeFree
Seizures 0.000271442 1 0 BeFree
Choreoathetosis 0.000271442 1 0 BeFree
Tumor Progression 0.000271442 1 0 BeFree
Congenital anomaly of face 0.000271442 1 0 BeFree
Basal ganglia calcification 0.000271442 1 0 BeFree
Mammary Neoplasms 0.000271442 1 0 BeFree
Intellectual Disability 0.000271442 1 0 BeFree

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