ANKK1(ankyrin repeat and kinase domain containing 1) 转至新版数据库

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

收起

11q23.2
基因染色体位置图

The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID:1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of ANKK1 gene (PMIDs: 18621654, 15146457), where it causes a nonconservative amino acid substitution. It is not clear if this gene plays any role in neuropsychiatric disorders previously associated with Taq1A RFLP. [provided by RefSeq, Sep 2009]

[中文简述(自动翻译):]  由该基因编码的蛋白质属于丝氨酸/苏氨酸蛋白激酶家族,和蛋白激酶超家族参与信号转导通路。该基因是紧密相连的DRD2基因(GeneID:1813)于CHR 11,并指定TaqIA一个很好的研究限制性片段长度多态性(RFLP),最初是与DRD2基因有关,但后来被确定为位于外显子8的ANKK1基因(PMIDs:18621654,15146457),在那里它会导致非保守氨基酸取代。如果这个基因在神经精神障碍预先用Taq1A RFLP相关的任何作用目前尚不清楚。 [由RefSeq的,2009年09月提供]

ANKK1基因的碱基序列:[NCBI]
ANKK1基因的碱基突变:           显示全部snp
rs877137       rs877138       rs1800497       rs2587553       rs2587555       rs2734847       rs2734848       rs2734849       rs2859545       rs4412783       rs4590907       rs4938012       rs4938013       rs4938014       rs4938015       rs4938016       rs6589375       rs7104979       rs7105965       rs7107223       rs7118900       rs7119146       rs7122228       rs7122884       rs7123797       rs7929146       rs7944809       rs7944911       rs7945132       rs10891543       rs10891544       rs10891545       rs10891546       rs10891547       rs10891548       rs11214594       rs11214595      
rs11214597       rs11214598       rs11214599       rs11604671       rs11823773       rs12224538       rs12283701       rs12286468       rs12289164       rs12360992       rs12419751       rs12800370       rs12800571       rs12800720       rs12801947       rs12807729       rs17115439       rs17115457       rs17115461       rs17600713       rs34298987       rs34601878       rs34716641       rs34863235       rs34983219       rs35023999       rs35488601       rs35657708       rs35877321       rs45466992       rs45612940       rs55699907       rs55787008       rs55849504       rs56005821       rs56006094       rs56047699       rs56299709       rs56339158       rs56947174       rs57840711       rs57972373       rs58224139       rs59592568       rs61492892       rs71477207       rs73557236       rs74694633       rs74937448       rs75252750       rs75375416       rs75455436       rs75619076       rs75698063       rs76776816       rs76868518       rs77077463       rs77145822       rs77485056       rs78124723       rs78136394       rs78229381       rs78294376       rs78343810       rs78723699       rs79128514       rs79697484       rs79729047       rs79893539       rs80141781       rs111327013       rs111334073       rs111411852       rs111421478       rs111599946       rs111613156       rs111789052       rs111849946       rs112038210       rs112100454       rs112103551       rs112214553       rs112241077       rs112318042       rs112490516       rs113005509       rs113371710       rs113584199       rs113826933       rs113906301       rs114634738       rs114700049       rs114931186       rs114962468       rs114976452       rs115800217       rs115874929       rs115878013       rs116253809       rs116255469       rs116301531       rs116403820       rs116747150       rs116860190       rs117124358       rs117211128       rs117352857       rs117599758       rs137912023       rs138608171       rs138608984       rs139014628       rs139054194       rs139195339       rs139270089       rs139374310       rs139841238       rs139904975       rs140060656       rs140187145       rs140261766       rs140803658       rs140819428       rs140888888       rs140953403       rs141224166       rs141919233       rs142254936       rs142311408       rs142312937       rs142328839       rs142374328       rs142433124       rs142615708       rs143395565       rs143482544       rs143752738       rs144268981       rs144613657       rs144753967       rs144826110       rs145595688       rs145957636       rs146143203       rs146480879       rs146498786       rs147474296       rs147886949       rs148011471       rs148171600       rs148218727       rs148532545       rs148862167       rs148904173       rs149265424       rs149650539       rs149987192       rs150042047       rs150137286       rs150352049       rs150627679       rs150678579       rs151031287       rs151227592       rs181016170       rs181290878       rs181651283       rs181883517       rs182667275       rs183156766       rs183404288       rs183544007       rs184252223       rs184325306       rs184429656       rs184645039       rs184857460       rs184964179       rs185098406       rs185694634       rs186045677       rs186633697       rs186677042       rs186810304       rs187491400       rs188212551       rs188381597       rs188406956       rs188850620       rs189087444       rs189173179       rs189187004       rs189203413       rs189730476       rs190009110       rs190030322       rs190515016       rs190581039       rs190853485       rs192344530       rs192444793       rs192587080       rs192740232       rs192829760       rs199570081       rs199582150       rs199662373       rs199747130       rs199783502       rs199896606       rs199986656       rs199995142       rs200005080       rs200099073       rs200103052       rs200273061       rs200344768       rs200473079       rs200549519       rs200624485       rs200699123       rs200745528       rs200848219       rs200848862       rs201008406       rs201092692       rs201098042       rs201120012       rs201185165       rs201207634       rs201257762       rs201291015       rs201489078       rs201580434       rs201608349       rs201856441       rs201891002       rs201901607       rs201933022       rs202009146       rs202206437       rs202222056       rs267602696       rs267602697       rs367585993       rs367599961       rs367629143       rs367944155       rs367992103       rs368013869       rs368179456       rs368483324       rs368657217       rs368774233       rs368854368       rs368972146       rs369034375       rs369211659       rs369229013       rs369359821       rs369403733       rs369480293       rs369606725       rs369753671       rs369803292       rs370140219       rs370146394       rs370229308       rs370257049       rs370260506       rs370450329       rs370538192       rs370756598       rs370845020       rs370893401       rs370967162       rs371011304       rs371127439       rs371357060       rs371374955       rs371425911       rs371434196       rs371542276       rs371548639       rs371658883       rs371672361       rs371693492       rs371779915       rs371889477       rs371927986       rs372213372       rs372375844       rs372375983       rs372415440       rs372461990       rs372467643       rs372776088       rs372845149       rs373051400       rs373295480       rs373311747       rs373818636       rs373849007       rs373856752       rs373888683       rs373974422       rs374171189       rs374405889       rs374434021       rs374577982       rs374674911       rs374980288       rs374985284       rs375233628       rs375251188       rs375367141       rs375817372       rs375843671       rs375875018       rs375895682       rs375917085       rs376025379       rs376080076       rs376083353       rs376195155       rs376444957       rs376599631       rs376661130       rs376689251       rs376720069       rs376917707       rs377018695       rs377262479       rs377362450       rs377443317       rs377621768       rs527482474       rs527563731       rs527816093       rs528066691       rs528190275       rs528223767       rs528493392       rs528503908       rs528571685       rs528706694       rs528891737       rs528904369       rs529105798       rs529846460       rs529893800       rs530059726       rs530168609       rs530549465       rs530818161       rs530835710       rs530922563       rs531004486       rs531041451       rs531200975       rs531342920       rs531538356       rs531548268       rs531806602       rs532324351       rs532526670       rs532549594       rs532907853       rs533086046       rs533178221       rs533347208       rs533486914       rs533706000       rs533955431       rs534227613       rs534277847       rs534336933       rs534472707       rs534920143       rs534922469       rs535188032       rs535602626       rs535913227       rs535938237       rs536004180       rs536353851       rs536586639       rs536604235       rs536664287       rs537006404       rs537595518       rs537608034       rs537660012       rs537989739       rs538322395       rs538351331       rs538384101       rs538390734       rs538609167       rs538704036       rs538752260       rs538997919       rs539439204       rs540305930       rs540311663       rs540571046       rs540581246       rs540909576       rs540972917       rs540973002       rs541172883       rs541201148       rs541605810       rs541623455       rs542555626       rs542686972       rs542720897       rs542786384       rs542956597       rs543329539       rs543390926       rs543567673       rs543679524       rs543981526       rs543989529       rs544371519       rs544558347       rs544565569       rs544888188       rs544904141       rs545012068       rs545233316       rs545659245       rs545702309       rs545925009       rs545943210       rs546196832       rs546761740       rs546828439       rs546909611       rs547140030       rs547155475       rs547157310       rs547220937       rs547885547       rs548327411       rs548499152       rs548605784       rs548890487       rs548902967       rs548932920       rs549132402       rs549457096       rs549933881       rs550220566       rs550568398       rs551241953       rs551259689       rs551638193       rs551774128       rs551851449       rs552577226       rs552623937       rs552899614       rs552913646       rs552946228       rs553170003       rs553234761       rs553522121       rs553777847       rs553782514       rs553843033       rs554171750       rs554233180       rs554442253       rs554464632       rs554799863       rs555230607       rs555294019       rs555490493       rs555529266       rs555754435       rs555996580       rs556237092       rs556578276       rs556827862       rs556889071       rs556979499       rs557153939       rs558224126       rs558241176       rs558423348       rs558454981       rs558649991       rs558913172       rs559226869       rs559839708       rs559901781       rs559931943       rs560069921       rs560243767       rs560291331       rs560302762       rs560430939       rs561069186       rs561227329       rs561438663       rs561588687       rs561651360       rs561844753       rs562101454       rs562149590       rs562162745       rs562309450       rs562442818       rs562504154       rs563161739       rs563371213       rs563761119       rs563764091       rs563826955       rs564113486       rs564127431       rs564355960       rs564396536       rs564538160       rs564717313       rs564794313       rs564853896       rs565039039       rs565434995       rs565700593       rs566041628       rs566056674       rs566266603       rs566279005       rs566340446       rs566701242       rs566736297       rs566764295       rs567021359       rs567327813       rs567372060       rs567384089       rs567443651       rs567602432       rs567763343       rs567923936       rs568094706       rs568108650       rs568242765       rs568526110       rs568730201       rs568795029       rs569015676       rs569017315       rs569080621       rs569702532       rs569959437       rs570011941       rs570078679       rs570470666       rs570999136       rs571088308       rs571184191       rs571311306       rs571374032       rs571407923       rs571482101       rs571695934       rs571708466       rs571984122       rs572196730       rs572330453       rs572485580       rs572602753       rs572665249       rs572680584       rs573349413       rs573683578       rs573967499       rs574962365       rs575194800       rs575543511       rs575662964       rs576022535       rs576630220       rs576969390       rs577345549       rs577726173       rs577839226       rs577943707       rs577971928       rs745319156       rs745375509       rs745509772       rs745661789       rs745688052       rs745709446       rs745836123       rs745898839       rs745998002       rs746160993       rs746175705       rs746286015       rs746405597       rs746484784       rs746512232       rs746810790       rs746825984       rs746867767       rs746946713       rs747016489       rs747222225       rs747313017       rs747315358       rs747431363       rs747460465       rs747507046       rs747682799       rs747740456       rs747828811       rs747871327       rs747909885       rs748104280       rs748183613       rs748225627       rs748449030       rs748510327       rs748655600       rs748677947       rs748741541       rs748889388       rs748891836       rs748945337       rs749026743       rs749107081       rs749145473       rs749315416       rs749486188       rs749542760       rs749549783       rs749672480       rs749723673       rs749805635       rs749849059       rs749895054       rs750066376       rs750102788       rs750122749       rs750249198       rs750295808       rs750392041       rs750469108       rs750700049       rs751021149       rs751094655       rs751262148       rs751344795       rs751399807       rs751405790       rs751543797       rs751601411       rs751745565       rs751757498       rs751893680       rs752026138       rs752191051       rs752321920       rs752421459       rs752543600       rs752600844       rs752607191       rs752663041       rs752755426       rs752893588       rs752944884       rs753012655       rs753060269       rs753097769       rs753165961       rs753308199       rs753463597       rs753702547       rs753749929       rs753870135       rs753990582       rs754110855       rs754141107       rs754272864       rs754594883       rs754614871       rs754689421       rs754746606       rs754981267       rs755210488       rs755322242       rs755428982       rs755567864       rs755664137       rs755727113       rs755742742       rs755794208       rs755871724       rs755882106       rs756006435       rs756137100       rs756224912       rs756250479       rs756305840       rs756412729       rs756414586       rs757065955       rs757194170       rs757199134       rs757210309       rs757311568       rs757386062       rs757511479       rs757598463       rs757998438       rs758040982       rs758081480       rs758090485       rs758186532       rs758194853       rs758224977       rs758330991       rs758647732       rs758657165       rs758753125       rs758859054       rs758884619       rs758905204       rs758918594       rs759009323       rs759222838       rs759401413       rs759484432       rs759484490       rs759853241       rs759932696       rs759973935       rs759984734       rs759985767       rs760021366       rs760177292       rs760323991       rs760355089       rs760424591       rs760473928       rs760555606       rs760609097       rs760664294       rs760737435       rs760834011       rs760851649       rs760983332       rs761103021       rs761119338       rs761182876       rs761318999       rs761353002       rs761504873       rs761528851       rs761556263       rs761574984       rs761764250       rs762136964       rs762261977       rs762307884       rs762324123       rs762467513       rs762488989       rs762838778       rs762879240       rs762904450       rs763014604       rs763071653       rs763198483       rs763284159       rs763382471       rs763475951       rs763567025       rs763823018       rs763876795       rs763885896       rs763956667       rs763962543       rs764020314       rs764024565       rs764114256       rs764167206       rs764432409       rs764568482       rs764568661       rs764581391       rs764713503       rs764865469       rs764920531       rs765015422       rs765043339       rs765090507       rs765099713       rs765134129       rs765157742       rs765213302       rs765409298       rs765529414       rs765549397       rs765724932       rs766047837       rs766264073       rs766309204       rs766353530       rs766436729       rs766574145       rs766798510       rs766803430       rs767086566       rs767125783       rs767142506       rs767292061       rs767343068       rs767390633       rs767524618       rs767569803       rs767728135       rs767910276       rs768126694       rs768301944       rs768361670       rs768363214       rs768460251       rs768518656       rs768579058       rs768585529       rs768742229       rs768853026       rs769090343       rs769225984       rs769230164       rs769281005       rs769352838       rs769430211       rs769529971       rs769920822       rs769944298       rs769944370       rs770067206       rs770151569       rs770164219       rs770245667       rs770325532       rs770373484       rs770374358       rs770430581       rs770433770       rs770440138       rs770459701       rs770514908       rs770683785       rs770968848       rs770969694       rs770983683       rs771060056       rs771306482       rs771309001       rs771319801       rs771400471       rs771504640       rs771592036       rs771630599       rs771643471       rs771655767       rs771735925       rs771782185       rs772090369       rs772170574       rs772173553       rs772246720       rs772400827       rs772652925       rs772721743       rs772759363       rs772847732       rs772886559       rs772999561       rs773076411       rs773201249       rs773282594       rs773284460       rs773464053       rs773594486       rs773748715       rs773765126       rs773785910       rs773796958       rs773971137       rs774031844       rs774257167       rs774293394       rs774294438       rs774312122       rs774363217       rs774414528       rs774419815       rs774471207       rs774912504       rs774939626       rs774992704       rs775048985       rs775195626       rs775266427       rs775389248       rs775420902       rs775477797       rs775487122       rs775667496       rs775748000       rs775999058       rs776006454       rs776054755       rs776121430       rs776205916       rs776249480       rs776414479       rs776608837       rs776693749       rs776925300       rs777011321       rs777083250       rs777136605       rs777160724       rs777287461       rs777568475       rs777770244       rs777823114       rs777904607       rs777944210       rs778011522       rs778061889       rs778061993       rs778216005       rs778503691       rs778583811       rs778908684       rs778983207       rs779011394       rs779036343       rs779083285       rs779203170       rs779360079       rs779449194       rs779530025       rs779573357       rs779673107       rs779726205       rs779731641       rs780023844       rs780054479       rs780077714       rs780138274       rs780291642       rs780396307       rs780438636       rs780529370       rs780584250       rs780679850       rs780692423       rs780717496       rs780859079       rs780862065       rs780918392       rs780936187       rs780977702       rs781184379       rs781363250       rs781442189       rs781499658       rs781581458       rs781630961       rs781690793       rs781760767       rs781774558       rs869034590      

ANKK1基因在不同组织中的表达:    [UniProt]

基因在不同组织中的表达图
正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
CAGGACCTAAATATGATGTGTACAG
59
CATGTTGAACCCTGAGTATGG
59
TGATGGACAGTGACTCAGG
59
CATAGATACACAGTTCCTCATCTC
58
CATGAACTTCCTGCACAGC
60
CAGTTTCTTCACTTTGACATGC
59
CAGGACCTAAATATGATGTGTACAG
59
TGTTGAACCCTGAGTATGGT
59
CAGGACCTAAATATGATGTGTACAG
59
ATGTTGAACCCTGAGTATGGT
59
TGATGGACAGTGACTCAGG
59
TCATAGATACACAGTTCCTCATCTC
60
CCATGAACTTCCTGCACAG
59
CAGTTTCTTCACTTTGACATGC
59
GATGGACAGTGACTCAGGA
58
CATAGATACACAGTTCCTCATCTC
58
TTCCTGCACAGCATTAAGC
59
CAGTTTCTTCACTTTGACATGC
59
      尚未收录相关数据

ANKK1基因(以及对应的蛋白质)的细胞分布位置:

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

ANKK1基因的本体(GO)信息:

GO库代码
对应的蛋白质
来源代码
GO:0004672
H0YH32(UniProtKB)
IEA
GO:0005524
H0YH32(UniProtKB)
IEA
GO:0006468
H0YH32(UniProtKB)
IEA
GO:0004674
Q8NFD2(UniProtKB)
IEA
GO:0005524
Q8NFD2(UniProtKB)
IEA
GO:0006468
Q8NFD2(UniProtKB)
IEA
基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

可能调控ANKK1基因的相关microRNA:     


通路基因列表
疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Language Disorders 0.120271442 1 0 BeFree_CTD_human
DOPAMINE RECEPTOR D2, REDUCED BRAIN DENSITY OF 0.12 0 1 CLINVAR
Alcoholic Intoxication, Chronic 0.017078432 19 0 BeFree_GAD_LHGDN
Schizophrenia 0.009087065 7 3 BeFree_GAD_LHGDN
Dyskinetic syndrome 0.005720142 3 0 BeFree_LHGDN
Obesity 0.005276948 4 1 BeFree_GAD
Tobacco Use Disorder 0.004734064 2 1 GAD
Nicotine Dependence 0.004267125 7 2 BeFree_GAD
Marijuana Abuse 0.002909916 3 10 BeFree_GAD
Neuroleptic Malignant Syndrome 0.00272435 1 0 LHGDN
nervous system disorder 0.002638474 2 0 BeFree_GAD
As If Personality 0.002367032 1 0 GAD
Malignant neoplasm of urinary bladder 0.002367032 1 0 GAD
Esophageal Neoplasms 0.002367032 1 0 GAD
Fatigue 0.002367032 1 0 GAD
Head and Neck Neoplasms 0.002367032 1 0 GAD
Hyperphagia 0.002367032 1 0 GAD
Laryngeal neoplasm 0.002367032 1 0 GAD
Mouth Neoplasms 0.002367032 1 0 GAD
Opioid-Related Disorders 0.002367032 1 0 GAD
Pharyngeal Neoplasms 0.002367032 1 0 GAD
Polycystic Ovary Syndrome 0.002367032 1 1 GAD
Psychoses, Substance-Induced 0.002367032 1 0 GAD
Delayed Puberty 0.002367032 1 1 GAD
Precocious Puberty 0.002367032 1 1 GAD
Weight Gain 0.002367032 1 0 GAD
Ovarian Failure, Premature 0.002367032 1 1 GAD
Substance-Related Disorders 0.002367032 1 0 GAD
Thrombophilia 0.002367032 1 1 GAD
Weight Gain Adverse Event 0.002367032 1 0 GAD
Substance Dependence 0.001085767 4 0 BeFree
Antisocial Personality Disorder 0.000814326 3 0 BeFree
Bipolar Disorder 0.000814326 3 0 BeFree
Alexithymia 0.000542884 2 0 BeFree
Mental disorders 0.000542884 2 0 BeFree
Heroin Dependence 0.000542884 2 0 BeFree
Attention deficit hyperactivity disorder 0.000542884 2 1 BeFree
Drug Dependence 0.000542884 2 0 BeFree
alcohol use disorder 0.000271442 1 0 BeFree
Anxiety Disorders 0.000271442 1 1 BeFree
Cocaine Abuse 0.000271442 1 0 BeFree
Mental Depression 0.000271442 1 1 BeFree
Depressive disorder 0.000271442 1 1 BeFree
Diabetes Mellitus, Non-Insulin-Dependent 0.000271442 1 0 BeFree
Epilepsy 0.000271442 1 0 BeFree
Disruptive, Impulse Control, and Conduct Disorders 0.000271442 1 0 BeFree
melanoma 0.000271442 1 0 BeFree
Parkinson Disease 0.000271442 1 0 BeFree
Unipolar Depression 0.000271442 1 1 BeFree
Alcohol abuse 0.000271442 1 0 BeFree
Migraine Disorders 0.000271442 1 0 BeFree
Antisocial behavior 0.000271442 1 0 BeFree
Overweight 0.000271442 1 0 BeFree
Opiate Addiction 0.000271442 1 1 BeFree
Cocaine Dependence 0.000271442 1 0 BeFree
Bipolar I disorder 0.000271442 1 0 BeFree
Major Depressive Disorder 0.000271442 1 1 BeFree
NEUROTICISM 0.000271442 1 1 BeFree
Executive dysfunction 0.000271442 1 0 BeFree
没有相关文献
我要说两句
热门评论
还没有评论,赶快来抢沙发吧。

登陆

用户名:

密    码:

联系方式

山东省济南市 高新区 崇华路359号 三庆世纪财富中心C1115室

电话: 0531-88819269

E-mail: product@genelibs.com

微信公众号

扫一扫右方二维码,关注微信订阅号,实时查看信息,关注医学生物学动态。