AMELX(amelogenin, X-linked) 转至新版数据库

基因基本信息

基因基本信息

基因简称(symbol)
    [HGNC]     [GeneCards]     [NCBI]
基因种类(locus group)
同源简称(alias symbol)
基因家族代码(gene_family_id)
    [HGNC]     [GenScript]
omim代码
entrez码
    [Vega]
vega基因码
ensembl基因码
    [Ensembl]
基因家族(gene family)
refseq数据库代号

更多...

基因种类(locus_type)
基因名称状态(status)
location_sortable
同源基因名称(alias name)
基因名称批准使用时间(date_approved_reserved)
基因简称更名时间(date_symbol_changed)
基因名称更名时间(date_name_changed)
更新时间(date_modified)
ucsc码
ena
ccds数据码
uniprot数据码
pubmed代码
mgd码
rgd码
生命科学数据库(lsdb)
更新时间(date modified)
cosmic
mirbase
基因曾用简称(prev symbol)
基因曾用名称(prev name)
homeodb
cosmic
snornabase
bioparadigms slc
orphanet
假基因信息(pseudogeneorg)
horde id
merops
imgt
iuphar
kznf基因类别
mamit-trnadb
cd
LncRNA数据库
酶代码
中间纤维数据库

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基因染色体位置

基因染色体位置

Xp22.31-p22.1
基因染色体位置图

基因简述

基因简述

This gene encodes a member of the amelogenin family of extracellular matrix proteins. Amelogenins are involved in biomineralization during tooth enamel development. Mutations in this gene cause X-linked amelogenesis imperfecta. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

[中文简述(自动翻译):]  该基因编码的釉原蛋白家族细胞外基质蛋白中的一员。 Amelogenins是牙釉质发育过程中涉及的生物矿化。突变这个基因导致X连锁amelogenesis不全。在多个转录剪接变异体导致编码不同亚型。 [由RefSeq的，2008年7月提供]

OMIM数据库中对AMELX基因的介绍     Wikipedia数据库中对AMELX基因的介绍

基因序列

基因序列

AMELX基因的碱基序列：[NCBI]

基因突变

基因突变

AMELX基因的碱基突变：           显示全部snp
rs780941596       rs781175862       rs781662544       rs780693229       rs780818544       rs780365505       rs780598313       rs779831463       rs779934052       rs780336512       rs779655130       rs779785692       rs779323924       rs779172647       rs779253128       rs779277633       rs779075042       rs778814190       rs778592437       rs778689286       rs778715775       rs778441921       rs778170205       rs778080525       rs778112293       rs777719857       rs777654066       rs777172917       rs777235911       rs777274203       rs776762719       rs777018247       rs776692529       rs776624092       rs776675035       rs776551701       rs776437048      
rs776065625       rs775957398       rs775826448       rs775768556       rs775163233       rs774922647       rs774986458       rs774798326       rs774792121       rs774439738       rs774054710       rs773812418       rs773760898       rs773295163       rs773668995       rs773277711       rs773210099       rs773193332       rs772861040       rs773161383       rs772844760       rs772586009       rs772491184       rs772080502       rs771933695       rs771907722       rs771775925       rs771416423       rs771336026       rs771385765       rs771211286       rs770771001       rs771054226       rs770571238       rs770491805       rs770333397       rs769808912       rs769567581       rs769670776       rs769182484       rs769206570       rs769158903       rs768768651       rs768435519       rs768417162       rs768186118       rs768159489       rs768133135       rs767901808       rs767746664       rs767687974       rs767685604       rs767502016       rs767414187       rs767197248       rs766963883       rs767136874       rs766873495       rs766939481       rs766401250       rs765687165       rs765441386       rs765395137       rs765306052       rs764959956       rs765286677       rs764950545       rs764911951       rs764860638       rs764237259       rs764805160       rs764111119       rs764153884       rs764063679       rs763879193       rs763844854       rs763630956       rs763177333       rs763006746       rs762731577       rs762338830       rs762327479       rs762158191       rs761524591       rs761996476       rs761389595       rs761478010       rs761293454       rs760940170       rs760833895       rs760816970       rs760773555       rs760714398       rs760691566       rs760464147       rs760321133       rs760209734       rs760145611       rs760125073       rs759964053       rs759949751       rs759784894       rs759477208       rs759170832       rs758945581       rs758813809       rs758774073       rs758391877       rs758376502       rs758319461       rs758319153       rs758160581       rs758182909       rs757918555       rs757235287       rs757604788       rs757151709       rs757162750       rs756968232       rs756696851       rs756431625       rs756541454       rs756297837       rs755871234       rs755797941       rs755674508       rs755554117       rs755272228       rs755158864       rs755035318       rs754995405       rs754937993       rs754945811       rs754887083       rs754750624       rs754639418       rs754292311       rs754218426       rs754022687       rs753863554       rs753643916       rs753460403       rs753327781       rs753353107       rs753003209       rs752708064       rs752525169       rs752442424       rs752443593       rs752404330       rs752308034       rs752151612       rs752106972       rs751602067       rs751652555       rs751474750       rs751462537       rs751302355       rs750746199       rs751135700       rs750739349       rs750626855       rs750389899       rs750299843       rs750270295       rs750108771       rs749967892       rs749844204       rs749650835       rs749729180       rs749486136       rs749309419       rs749213434       rs749192334       rs749154172       rs748638870       rs748483718       rs748301023       rs748166713       rs747710271       rs747518238       rs747112409       rs746714110       rs746586312       rs746508249       rs746272574       rs745846151       rs745822682       rs745626684       rs745396130       rs745320292       rs546491617       rs550452317       rs431825177       rs538583130       rs375383821       rs376830760       rs374272157       rs373812581       rs373800800       rs373394187       rs372488657       rs372332800       rs369891804       rs371530769       rs369247345       rs368149347       rs368528630       rs367556910       rs201968803       rs201515468       rs201340651       rs201127558       rs200884777       rs200842202       rs200715488       rs200163085       rs200101076       rs193109828       rs192708703       rs192423084       rs191399494       rs191283789       rs190979631       rs190765372       rs190519078       rs189693213       rs189269778       rs188870538       rs188865418       rs188715671       rs188239171       rs187878160       rs187559058       rs187280112       rs186757333       rs186498436       rs186211236       rs185908195       rs185763648       rs184827613       rs184371797       rs184363677       rs184311581       rs183940749       rs183365414       rs183198858       rs182747238       rs182720635       rs182609965       rs181659103       rs181617517       rs181540792       rs181251476       rs180981314       rs150971901       rs180886848       rs150631365       rs149923681       rs149205639       rs149068672       rs148259441       rs148733869       rs147804735       rs147768666       rs147108420       rs146287857       rs147013110       rs146067760       rs145680107       rs145299463       rs144955572       rs143860203       rs143417337       rs142884100       rs142795990       rs142015350       rs140683312       rs139757230       rs139566596       rs139502132       rs139137288       rs138892868       rs138249749       rs112174012       rs111367666       rs104894734       rs76204911       rs78962455       rs34793505       rs41305177       rs34506169       rs17878486       rs16986396       rs12834615       rs11299160       rs10126400       rs7052450       rs6654939       rs6530435       rs5979395       rs5979394       rs5934997       rs5934996       rs5933871       rs3810738       rs2106416       rs1265860       rs946252       rs946251       rs929190      

基因表达

基因表达

AMELX基因在不同组织中的表达：    [UniProt]

基因在不同组织中的表达图

基因引物

基因引物

正向引物序列
正向引物Tm值
反向引物序列
反向引物Tm值
rank
TTTATTTGCCTGCCTCCTG
58
TAACCATAGGAAGGGTACGG
58
TCAATGTTGACAGGACTGC
58
AACCATAGGAAGGGTACGG
59
TTTATTTGCCTGCCTCCTG
58
AACCATAGGAAGGGTACGG
59
CACCCTGGTTATATCAACTTCAG
59
GGGTAAGCACTAATGCAGTC
59
CCCTGGTTATATCAACTTCAGC
59
CATAGGAAGGGTACGGTGG
59
CTATCAATGTTGACAGGACTGC
60
CATAGGAAGGGTACGGTGG
59
CCCTGGTTATATCAACTTCAGC
59
CCATAGGAAGGGTACGGTG
59
ACTTCAGCTATGAGGTGCT
58
ATGGGCTCGTAACCATAGG
59
ACAGGACTGCATTAGTGCT
59
ATGGGCTCGTAACCATAGG
59
TATCAATGTTGACAGGACTGC
59
CCATAGGAAGGGTACGGTG
59

转录因子

转录因子

      尚未收录相关数据

基因本体信息

AMELX基因（以及对应的蛋白质）的细胞分布位置：

[UniProt]     [GenomeNet]

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
  • 溶酶体
  • 内涵体
  • 细胞核
  • 细胞质
  • 液泡
  • 细胞膜
  • 细胞外基质
  • 内质网
  • 线粒体
  • 高尔基体
  • 细胞骨架

AMELX基因的本体（GO）信息：

GO库代码
对应的蛋白质
来源代码
GO:0001649
Q99217(UniProtKB)
ISS
GO:0001837
Q99217(UniProtKB)
ISS
GO:0002062
Q99217(UniProtKB)
ISS
GO:0005515
Q99217(UniProtKB)
IPI
GO:0005578
Q99217(UniProtKB)
IDA
GO:0007155
Q99217(UniProtKB)
ISS
GO:0007165
Q99217(UniProtKB)
TAS
GO:0008083
Q99217(UniProtKB)
ISS
GO:0008283
Q99217(UniProtKB)
ISS
GO:0009986
Q99217(UniProtKB)
ISS
GO:0030345
Q99217(UniProtKB)
IMP
GO:0030345
Q99217(UniProtKB)
IDA
GO:0030345
Q99217(UniProtKB)
IDA
GO:0031214
Q99217(UniProtKB)
TAS
GO:0032967
Q99217(UniProtKB)
ISS
GO:0034505
Q99217(UniProtKB)
IMP
GO:0034505
Q99217(UniProtKB)
ISS
GO:0042475
Q99217(UniProtKB)
ISS
GO:0042802
Q99217(UniProtKB)
ISS
GO:0046848
Q99217(UniProtKB)
ISS
GO:0050801
Q99217(UniProtKB)
TAS
GO:0070166
Q99217(UniProtKB)
IMP
GO:0070172
Q99217(UniProtKB)
TAS

基因相互作用关系

基因相互作用关系

基因与其他基因之间的相互作用关系图
序号 作用方式 资源库来源/分值 基因名称 基因名称

基因相关microRNA

基因相关microRNA

可能调控AMELX基因的相关microRNA：     

基因通路图

基因通路图

基因的通路属性图
通路基因列表

基因相关疾病

基因相关疾病

疾病名称 关系值 NofPmids NofSnps 来源
疾病名称 关系值 NofPmids NofSnps 来源
Amelogenesis Imperfecta hypomaturation type 0.12 0 0 ORPHANET
AMELOGENESIS IMPERFECTA, HYPOPLASTIC/HYPOMATURATION, X-LINKED 1 0.12 0 0 CTD_human
Amelogenesis Imperfecta, Hypomaturation Type, with Snow-Capped Teeth 0.12 3 0 UNIPROT
Hypocalcemia 0.08 1 0 RGD
Amelogenesis Imperfecta 0.008977445 15 0 BeFree_LHGDN
Dental caries 0.002909916 3 0 BeFree_GAD
Hematocrit level 0.002367032 1 1 GAD
Hepatitis, Autoimmune 0.001085767 4 0 BeFree
Hypercholesterolemia, Familial 0.000814326 3 0 BeFree
Malignant neoplasm of prostate 0.000814326 3 0 BeFree
Prostate carcinoma 0.000814326 3 0 BeFree
Leukemia, Myelocytic, Acute 0.000542884 2 0 BeFree
Xenograft Model 0.000542884 2 0 BeFree
Congenital Abnormality 0.000271442 1 0 BeFree
Arthritis 0.000271442 1 0 BeFree
Malignant neoplasm of breast 0.000271442 1 0 BeFree
Primary biliary cirrhosis 0.000271442 1 0 BeFree
Colorectal Carcinoma 0.000271442 1 0 BeFree
Lupus Erythematosus, Systemic 0.000271442 1 0 BeFree
Seizures 0.000271442 1 0 BeFree
Severe Combined Immunodeficiency 0.000271442 1 0 BeFree
Chronic pain 0.000271442 1 0 BeFree
Caries (morphologic abnormality) 0.000271442 1 0 BeFree
Breast Carcinoma 0.000271442 1 0 BeFree
Adenocarcinoma of large intestine 0.000271442 1 0 BeFree
Tumor Angiogenesis 0.000271442 1 0 BeFree
Colorectal Cancer 0.000271442 1 0 BeFree

基因相关文献

基因相关文献

基因相关服务

基因相关服务

基因评论

基因评论

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